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MNTEAGHSWLPRTSCDISCVSLGHPAVPRRVPATLRVALRIVWALLLMPGLPLLGVPVPGRSHAQRAYCR LVLRCFGVRITVSGSPIRNLRGVLVVSNHISWLDVFAIGAVLPGSFVARADMFTGPGVEIVARLLKIIPI ERTSLRRLPGVVDTVARRLRAGQTVVAFPEGTTWCGLASGSFYPAMFQAAIDAGRPVQPLRLTYHHVNGA ISTTPAFVGDDTLARSVRRVLAVRRIVASVHVDSLQLPGRDRRALASRCQSAVHAGAAHPAHRPALVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1687 | - | - | 100% (278) | hypothetical protein MMAR_1687 |
| M. marinum M | MMAR_5379 | - | 7e-07 | 30.82% (146) | acyltransferase |
| M. marinum M | MMAR_3834 | plsC | 5e-06 | 21.83% (229) | bifunctional transmembrane phospholipid biosynthesis enzyme |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3052c | - | 1e-110 | 71.79% (280) | hypothetical protein Mb3052c |
| M. gilvum PYR-GCK | Mflv_4256 | - | 7e-93 | 62.74% (263) | phospholipid/glycerol acyltransferase |
| M. tuberculosis H37Rv | Rv3026c | - | 1e-110 | 71.79% (280) | hypothetical protein Rv3026c |
| M. leprae Br4923 | MLBr_01245 | - | 2e-08 | 23.61% (233) | putative transferase |
| M. abscessus ATCC 19977 | MAB_3358c | - | 8e-96 | 61.15% (278) | putative acyltransferase |
| M. avium 104 | MAV_3873 | - | 1e-101 | 66.21% (293) | 1-acylglycerol-3-phosphate O-acyltransferase |
| M. smegmatis MC2 155 | MSMEG_2356 | - | 1e-98 | 67.80% (264) | acyltransferase |
| M. thermoresistible (build 8) | TH_1106 | - | 2e-06 | 28.93% (121) | 1-acylglycerol-3-phosphate O-acyltransferase |
| M. ulcerans Agy99 | MUL_1925 | - | 1e-159 | 100.00% (278) | hypothetical protein MUL_1925 |
| M. vanbaalenii PYR-1 | Mvan_2104 | - | 5e-93 | 62.55% (267) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1687|M.marinum_M --------------------------------------------------
MUL_1925|M.ulcerans_Agy99 --------------------------------------------------
Mb3052c|M.bovis_AF2122/97 --------------------------------------------------
Rv3026c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3873|M.avium_104 --------------------------------------------------
Mflv_4256|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2104|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2356|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3358c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01245|M.leprae_Br4923 MSAFDENGTPKSGPEVRLPGSVAEILASPAGPQVGAFFDLDGTLVAGFTA
TH_1106|M.thermoresistible__bu --------------------------------------------------
MMAR_1687|M.marinum_M --------------------------------------------------
MUL_1925|M.ulcerans_Agy99 --------------------------------------------------
Mb3052c|M.bovis_AF2122/97 --------------------------------------------------
Rv3026c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3873|M.avium_104 --------------------------------------------------
Mflv_4256|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2104|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2356|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3358c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01245|M.leprae_Br4923 VILTHERLRRCDMGVGELLSMIQAGLNHTLGRIEFEDLIGKVSSALRGRL
TH_1106|M.thermoresistible__bu --------------------------------------------------
MMAR_1687|M.marinum_M --------------------------------------------------
MUL_1925|M.ulcerans_Agy99 --------------------------------------------------
Mb3052c|M.bovis_AF2122/97 --------------------------------------------------
Rv3026c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3873|M.avium_104 --------------------------------------------------
Mflv_4256|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2104|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2356|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3358c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01245|M.leprae_Br4923 LTDLEEIGERLFAQRIESRIYPEMRKLVQAHVARGHTVVLSSSALTIQVG
TH_1106|M.thermoresistible__bu --------------------------------------------------
MMAR_1687|M.marinum_M --------------------------------------------------
MUL_1925|M.ulcerans_Agy99 --------------------------------------------------
Mb3052c|M.bovis_AF2122/97 --------------------------------------------------
Rv3026c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3873|M.avium_104 --------------------------------------------------
Mflv_4256|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2104|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2356|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3358c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01245|M.leprae_Br4923 PVARFLGIAHMLTNKFEINEDGMLTGGVVKPILWGPGKAAAVQRFAAEHD
TH_1106|M.thermoresistible__bu --------------------------------------------------
MMAR_1687|M.marinum_M -------------------------MNTEAGHSWLPRTSCDISCVSLGHP
MUL_1925|M.ulcerans_Agy99 -------------------------MNTEAGHSWLPRTSCDISCVSLGHP
Mb3052c|M.bovis_AF2122/97 -----------------------MSAPAVTEHSWLPRATCGVSCVSVGDA
Rv3026c|M.tuberculosis_H37Rv -----------------------MSAPAVTEHSWLPRATCGVSCVSVGDA
MAV_3873|M.avium_104 --------------------------------------------MAAGRP
Mflv_4256|M.gilvum_PYR-GCK -------------------------MTVTDGHAWLQAATCGAGCVDAGAD
Mvan_2104|M.vanbaalenii_PYR-1 -------------------------MTLIHEHAWLQPATCGAGCVHAGAD
MSMEG_2356|M.smegmatis_MC2_155 --------------------------MTTREHPWLPKASCDAGCVHSVEQ
MAB_3358c|M.abscessus_ATCC_199 -------------------------MAPEYAHAWLPKATCDESCMRANLI
MLBr_01245|M.leprae_Br4923 IDLKDSYFYADGDEDVALMYLVGNPRPTNPEGKMAAVAKRRGWPILKFNS
TH_1106|M.thermoresistible__bu --------------------------------------------------
MMAR_1687|M.marinum_M AVPRRVPATLRVALRIVWALLLMPGLPLLGVPVPGRSH----AQRAYCRL
MUL_1925|M.ulcerans_Agy99 AVPRRVPATLRVALRIVWALLLMPGLPLLGVPVPGRSH----AQRAYCRL
Mb3052c|M.bovis_AF2122/97 AQVRRPLVVLRVALRVMLALLLVPGVPLVVMPLPGRTR----VQRIYCRL
Rv3026c|M.tuberculosis_H37Rv AQVRRPLVVLRVALRVMLALLLVPGVPLVVMPLPGRTR----VQRIYCRL
MAV_3873|M.avium_104 AAERRLRVVVRVTLRLLLAVLLAPGWPLLAVPLPGRTR----VQRIYCRL
Mflv_4256|M.gilvum_PYR-GCK GPGRRWVVALRTGVRVSAALTLVTGVWLLALPLPGRSH----LQRGYCRL
Mvan_2104|M.vanbaalenii_PYR-1 GPGRRWVVALRTTVRVVAAVTLFAGVWLLALPLPGRSH----LQRGYCRL
MSMEG_2356|M.smegmatis_MC2_155 --GRRVIVWLRTAARLSAALALLPGMPLLAVPLPGRSH----VQRIYCRL
MAB_3358c|M.abscessus_ATCC_199 DEPGRFTRTFRTTSRIAMAITLLTLAPLLGIPLPGRVR----WQRGYCRL
MLBr_01245|M.leprae_Br4923 RGGVGIGAQLRTLVGLSSVLPLVAGAVGIGVLTGSRRRGANFFTSVFPPL
TH_1106|M.thermoresistible__bu ------------------MWYWLFKYILLGPLLAAIGR------------
: . :
MMAR_1687|M.marinum_M VLRCFGVRITVSGSP-IRNLRGVLVVSNHISWLDVFAIGAVLPG--SFVA
MUL_1925|M.ulcerans_Agy99 VLRCFGVRITVSGSP-IRNLRGVLVVSNHISWLDVFAIGAVLPG--SFVA
Mb3052c|M.bovis_AF2122/97 VLRLFGVRITVSGSP-VRNLRGVLVVSGHVSWLDVFCIGSVLPG--SFVA
Rv3026c|M.tuberculosis_H37Rv VLRLFGVRITVSGSP-VRNLRGVLVVSGHVSWLDVFCIGSVLPG--SFVA
MAV_3873|M.avium_104 VLRCFGVRITVSGNP-IRNLRGVLVVSPHTSWLDVFAIGAVLPG--SFVA
Mflv_4256|M.gilvum_PYR-GCK MLRSLGVRMSVAGGP-VRNLRGVLVVSGHVSWLDVFAIGTVLPG--SFVA
Mvan_2104|M.vanbaalenii_PYR-1 MLRSLGVRMSVSGGP-IRNLRGVLVVSGHVSWLDVFAIGTVLPG--SFVA
MSMEG_2356|M.smegmatis_MC2_155 LLRCLGVRIRLSGGP-IRNLQGVLVVSGHVSWLDIFAIGSVLPG--SFVA
MAB_3358c|M.abscessus_ATCC_199 MLRCLGVRISVSGGP-IRDIRGSLVVAGHVSWVDVFAIGAVLPG--SFVA
MLBr_01245|M.leprae_Br4923 VLAAAGVHLNVIGNENLTMQRPAVFIYNHRNQIDPLIAGALVRGNWIAVA
TH_1106|M.thermoresistible__bu --------PKVEGLENIPDSGAAILASNHLAVMDSFYLPLVVRRRITFLA
: * : :. * :* : :: :*
MMAR_1687|M.marinum_M RADMFTGPGVE-----IVARLLKIIPIERTSLRRLPGVVDTVARRLRAGQ
MUL_1925|M.ulcerans_Agy99 RADMFTGPGVE-----IVARLLKIIPIERTSLRRLPGVVDTVARRLRAGQ
Mb3052c|M.bovis_AF2122/97 RADMFTGRTIG-----IVARILKIIPIERASLRRLPGVVDTIARRLRAGQ
Rv3026c|M.tuberculosis_H37Rv RADMFTGRTIG-----IVARILKIIPIERASLRRLPGVVDTIARRLRAGQ
MAV_3873|M.avium_104 RADMFSGPATG-----VVARILKIIPIERSSLRRLPGVVDAVAHRLRAGQ
Mflv_4256|M.gilvum_PYR-GCK RADLVTWPALG-----PVVRLMKVIPIDRARLRRLPTVVASIADRLRAGQ
Mvan_2104|M.vanbaalenii_PYR-1 RADLVDWPALG-----PIVRIMKVIPIDRARLRRLPAVVAAVAGRLRAGY
MSMEG_2356|M.smegmatis_MC2_155 RADLVEWPALG-----RVARLMKVIPIDRASLRRLPAVVATVADRLRAGR
MAB_3358c|M.abscessus_ATCC_199 RADLIDWPGLG-----VIARMMRVIPIERGNLRTLPRVVGTVAARLRAGQ
MLBr_01245|M.leprae_Br4923 KKELAKNPIIR-----ALGKLTDGVFIDRDDPVGAVETLHAVEDRARKGL
TH_1106|M.thermoresistible__bu KSEYFTGTGVKGRFLAWFYTAVGQVPIDRTNADAAQDALDTAARIIGEGK
: : . : *:* .: : *
MMAR_1687|M.marinum_M TVVAFPEGTTWCGL---------------------------------ASG
MUL_1925|M.ulcerans_Agy99 TVVAFPEGTTWCGL---------------------------------ASG
Mb3052c|M.bovis_AF2122/97 TVVAFPEGTTWCGR--------------PGDDAGRPAARAGAGCSHRGCG
Rv3026c|M.tuberculosis_H37Rv TVVAFPEGTTWCGR--------------PGDDAGRPAARAGAGCSHRGCG
MAV_3873|M.avium_104 TVVAFPEGTTWCGRDGDDAGGGGGPSHTSGDDAGRGAAGGGGGPSHRGRG
Mflv_4256|M.gilvum_PYR-GCK TVVAFPEGTTWCGL---------------------------------GYG
Mvan_2104|M.vanbaalenii_PYR-1 TVVAFPEGTTWCGL---------------------------------GYG
MSMEG_2356|M.smegmatis_MC2_155 TVVAFPEGTTWCGL---------------------------------AHG
MAB_3358c|M.abscessus_ATCC_199 TVVAFPEGTTWCGR---------------------------------AYG
MLBr_01245|M.leprae_Br4923 SILMAPEGTRLDTT---------------------------------EVG
TH_1106|M.thermoresistible__bu LLGMYPEGTRSPDG---------------------------------RLY
: ****
MMAR_1687|M.marinum_M SFYPAMFQAAIDAGRPVQPLRLTYHHVNGA------------ISTTPAFV
MUL_1925|M.ulcerans_Agy99 SFYPAMFQAAIDAGRPVQPLRLTYHHVNGA------------ISTTPAFV
Mb3052c|M.bovis_AF2122/97 AFYPAMFQAAIDAGRPVQPLRLTYHHVDGT------------VSTAPAFV
Rv3026c|M.tuberculosis_H37Rv AFYPAMFQAAIDAGRPVQPLRLTYHHVDGT------------VSTAPAFV
MAV_3873|M.avium_104 AFYPAMFQAAIDAGRPVQPLRLTYQHVDGS------------TSTAPAFV
Mflv_4256|M.gilvum_PYR-GCK RFRPAMFQAAVDAGRPVQPLRVSYRHRDGR------------PSTVPAFV
Mvan_2104|M.vanbaalenii_PYR-1 RFRPAMFQAAIDAGRPVQPLRLSYRHKDGR------------PSTVPAFV
MSMEG_2356|M.smegmatis_MC2_155 PFRPAMFQAAVDAARPVQPLRLTYRHRDGR------------PSTTPAFV
MAB_3358c|M.abscessus_ATCC_199 SFRPAMFQAAVDAQRPVQPLRLTYHHLNGE------------LSTVPAYV
MLBr_01245|M.leprae_Br4923 PFKKGPFRIAMAVGIPIVPIVFRNAEIVAARNSNTINPGMVDVAVLPAIP
TH_1106|M.thermoresistible__bu KGKTGLARLALQTGAPVVPVAMIGTDVVNPPGKRGLRPG--RVQVKIGKP
. : *: . *: *: . . . .
MMAR_1687|M.marinum_M GDDTLARSVR-RVLAVRRIVASVHVDSLQLPGRDRRALASRCQSAVHAGA
MUL_1925|M.ulcerans_Agy99 GDDTLARSVR-RVLAVRRIVASVHVDSLQLPGRDRRALASRCQSAVHAGA
Mb3052c|M.bovis_AF2122/97 GDDTLVRSVC-RLLTVRRTLAWVRVESLQLPGTDRRNLARRCQSAVLAGA
Rv3026c|M.tuberculosis_H37Rv GDDTLVRSVC-RLLTVRRTLAWVRVESLQLPGTDRRNLARRCQSAVLAGA
MAV_3873|M.avium_104 GDETLLGSIR-RLLTVRRTLARVQVESLQLPGTDRRALAGRCQSAVGVAA
Mflv_4256|M.gilvum_PYR-GCK GDDSLLDSIT-RVITARRTVCHISVESLQLPGRDRRELAARCESAVRGHS
Mvan_2104|M.vanbaalenii_PYR-1 GDDTLLTSIK-RVITARRTVCHIHVESLQLPGVDRRDLAARCEAAVRGDA
MSMEG_2356|M.smegmatis_MC2_155 GQDTLLRSVC-RVVTARRTVCHVHVGALQLPGDDRRALAARCEAEVRG--
MAB_3358c|M.abscessus_ATCC_199 GEDTLMASIR-RLTATRMTVAHIRVAGLQLPGESRRDLAARCETAVRAGD
MLBr_01245|M.leprae_Br4923 VDDWTLDALS-ERIAEVRQLYLDILADWPVDELPKAALYTRATKATVKKA
TH_1106|M.thermoresistible__bu MDFSRFEGMAGNRFIERAVIDEVMYELMRLSGQEYVDLYAADVKKAALEA
: .: . : : * .
MMAR_1687|M.marinum_M AHPAHR----------------PALVA-----------------------
MUL_1925|M.ulcerans_Agy99 AHPAHR----------------PALVA-----------------------
Mb3052c|M.bovis_AF2122/97 LGQSGQRPG-------------RRHVPAT---------------------
Rv3026c|M.tuberculosis_H37Rv LGQSGQRPG-------------RRHVPAT---------------------
MAV_3873|M.avium_104 ARRAG--HG-------------RVLVA-----------------------
Mflv_4256|M.gilvum_PYR-GCK APVPRATAAACGGG--------HALVA-----------------------
Mvan_2104|M.vanbaalenii_PYR-1 GSSARRAISGCGGAGFAARGGNHTLVA-----------------------
MSMEG_2356|M.smegmatis_MC2_155 GHERRDART-------------HAIAA-----------------------
MAB_3358c|M.abscessus_ATCC_199 QIPQVHSHHHPEHPE-----RPEPIAA-----------------------
MLBr_01245|M.leprae_Br4923 EPKKGGRTSAAKTTAKKTATKATAAKTANTAVTKSMLTPPTRISDKENPK
TH_1106|M.thermoresistible__bu ADGTGGGKAATS----------SARIPDTAAG------------------
.
MMAR_1687|M.marinum_M ------------------
MUL_1925|M.ulcerans_Agy99 ------------------
Mb3052c|M.bovis_AF2122/97 ------------------
Rv3026c|M.tuberculosis_H37Rv ------------------
MAV_3873|M.avium_104 ------------------
Mflv_4256|M.gilvum_PYR-GCK ------------------
Mvan_2104|M.vanbaalenii_PYR-1 ------------------
MSMEG_2356|M.smegmatis_MC2_155 ------------------
MAB_3358c|M.abscessus_ATCC_199 ------------------
MLBr_01245|M.leprae_Br4923 VPKVVSQDLVVKQPRERS
TH_1106|M.thermoresistible__bu ------------------