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SVSAEPIFSLLIEHCDTCARWVHPATGRCDDCGAALVPRPVSGRGTVFTYTVNHHRYHPDIPTPYVIALV ELSEQAGLRVAANIVDCEPDSVTCGMPVAIRPERGTGGAPLFAPAGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1628 | - | - | 100% (118) | hypothetical protein MMAR_1628 |
| M. marinum M | MMAR_4731 | - | 1e-14 | 38.32% (107) | 3-ketoacyl-CoA thiolase |
| M. marinum M | MMAR_4248 | - | 6e-10 | 34.78% (92) | hypothetical protein MMAR_4248 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 4e-08 | 47.37% (57) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 9e-15 | 37.38% (107) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 4e-08 | 47.37% (57) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0616 | - | 2e-08 | 40.00% (75) | hypothetical protein MAB_0616 |
| M. avium 104 | MAV_3934 | - | 4e-49 | 80.19% (106) | hypothetical protein MAV_3934 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 7e-15 | 41.30% (92) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4518 | - | 6e-18 | 41.67% (108) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3408 | - | 2e-67 | 97.46% (118) | hypothetical protein MUL_3408 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 1e-14 | 36.45% (107) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1628|M.marinum_M ------------------MSVSAEPIFSLLIEHCDTCARWVHPATGRCDD
MUL_3408|M.ulcerans_Agy99 ------------------MSVSAEPIFSLLIEHCDTCARWVHPATGRCDD
MAV_3934|M.avium_104 --------------------MSDGP---LRIEYCDGCARWVHPASGRCRD
Mflv_2483|M.gilvum_PYR-GCK MSRLP----LPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRY
Mvan_4171|M.vanbaalenii_PYR-1 MSRLP----LPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRY
MSMEG_4814|M.smegmatis_MC2_155 MSQIPG-RPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRY
TH_4518|M.thermoresistible__bu MSAATDQRPVPLLTELNRPYWTGGAAGTWQLQRCDDCERLVHPPALRCPH
Mb3572c|M.bovis_AF2122/97 MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
Rv3542c|M.tuberculosis_H37Rv MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
MAB_0616|M.abscessus_ATCC_1997 MS-VVDIQEGFAKIKADGPSAPRLARDPVNQAMINNWVEAMGDRNPIYVD
:
MMAR_1628|M.marinum_M CGA-ALVPRP--VSGRGTVFTYTVNHHRYHPDIPTPYVIALVELSEQAGL
MUL_3408|M.ulcerans_Agy99 CDA-ALVPRP--VSGRGTVFTYTVNHHRYHPDIPTPYIIALVELSEQAGL
MAV_3934|M.avium_104 CGG-ALVARE--VCGRGTVFTYTVNHHPYNPEIPTPYVIAIVELAEQSDL
Mflv_2483|M.gilvum_PYR-GCK CHSHNMGPRE--VSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRV
Mvan_4171|M.vanbaalenii_PYR-1 CHSHNMGPRE--VSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRV
MSMEG_4814|M.smegmatis_MC2_155 CRSHDLGVRD--VSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRV
TH_4518|M.thermoresistible__bu DHG-VLRYVA--LRGRATVETWTVNEHPFFPGFPPPYVVAFVNPVEDERV
Mb3572c|M.bovis_AF2122/97 DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDP-LGPIIKLFDDAGY
Rv3542c|M.tuberculosis_H37Rv DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDP-LGPIIKLFDDAGY
MAB_0616|M.abscessus_ATCC_1997 EEAAKAAGHPGIVAPPAMAQVWTMAGLYGERSGDDP-LGRVMALLDSAGY
. : . :*: * : : :.
MMAR_1628|M.marinum_M R--VAANIVDCEPDSVTCGMPVAIRPE-----RGTGGAPLFAPAGR----
MUL_3408|M.ulcerans_Agy99 R--VAANIVDCEPDSVTCGMPVTIRPE-----RGTGGAPLFAPAGR----
MAV_3934|M.avium_104 R--VAANIVDCEPDSVTCGMPVTLLPE-----RGSGGAPRFAPA------
Mflv_2483|M.gilvum_PYR-GCK R--LTTNIVDCDPDELELGRVVEVVFE----QNEDVWLPLFRPTAEPETA
Mvan_4171|M.vanbaalenii_PYR-1 R--LTTNIIDCDPDELELGRVVEVVFE----ENDDVWLPLFRPTAETETA
MSMEG_4814|M.smegmatis_MC2_155 R--LTTNIVDCDPQSLELGQPVEVSFQ----HIDDVWLPVFTPSADTTPT
TH_4518|M.thermoresistible__bu R--VLTNLVNVRPEEVTAKMPVRVTFERYTDGDDEVYVPLFEPDL-----
Mb3572c|M.bovis_AF2122/97 IGVVATNCEQTYHRYLLPGEQVSISAE-----LGDVVGPKQTALGEGWFI
Rv3542c|M.tuberculosis_H37Rv IGVVATNCEQTYHRYLLPGEQVSISAE-----LGDVVGPKQTALGEGWFI
MAB_0616|M.abscessus_ATCC_1997 ESVVATNYEQIYHRYLELGEQVTTTNE-----VTEVFGPKQTALGESWFI
: :* : : * : * .
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK ALPDDEIAPQEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSL
Mvan_4171|M.vanbaalenii_PYR-1 PLPEDEIAPQDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSL
MSMEG_4814|M.smegmatis_MC2_155 PAPVEDIAPQDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSL
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 NQHIVWQVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPDAMMRPSSSRD
Rv3542c|M.tuberculosis_H37Rv NQHIVWQVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPDAMMRPSSSRD
MAB_0616|M.abscessus_ATCC_1997 NIHAEWHVGDELVNEMNWRIMKFRPGAKKAADVPQDLDPSKLMRPSWSRD
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TVEACEKAIADAGLTLADIDGLSTYPAMDAMGMGEGGCTVLEGALGIRPT
Mvan_4171|M.vanbaalenii_PYR-1 TVEACEAAIADAGLTLADIDGLSTYPAMDAMGMGEGGVTALEGALGIRPT
MSMEG_4814|M.smegmatis_MC2_155 TIEAAEQAVADAGLTFDDIDGLSTYPGLDIAGMGEGGVSVLEGALGLRPT
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 TAFFWDGVKAHELRIQRLADGSLRHPPVPAVWQDKSVPINYVVSSGRGTV
Rv3542c|M.tuberculosis_H37Rv TAFFWDGVKAHELRIQRLADGSLRHPPVPAVWQDKSVPINYVVSSGRGTV
MAB_0616|M.abscessus_ATCC_1997 SAYFWEGVAAHELRLQKRPDGSLQHPPVPAVWQDKEAPIEYQVASGRGTV
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK WINGGMDTFGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGKA
Mvan_4171|M.vanbaalenii_PYR-1 WINGGMDTFGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGRV
MSMEG_4814|M.smegmatis_MC2_155 WINGGMDTFGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKM
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 FS-----------FVVHHAPKVPGRTVPFVIALVELEEG-----------
Rv3542c|M.tuberculosis_H37Rv FS-----------FVVHHAPKVPGRTVPFVIALVELEEG-----------
MAB_0616|M.abscessus_ATCC_1997 YS-----------YVVHHAPQVPGRTLPFVIALVELDEG-----------
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK SPPGGARVNSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQR
Mvan_4171|M.vanbaalenii_PYR-1 SPPGGTRVNSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQR
MSMEG_4814|M.smegmatis_MC2_155 SPPMSARTNSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQR
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 -------VRMLGELRGADPARVAIGMPVRATYIDFPD------WSLYAWE
Rv3542c|M.tuberculosis_H37Rv -------VRMLGELRGADPARVAIGMPVRATYIDFPD------WSLYAWE
MAB_0616|M.abscessus_ATCC_1997 -------VRMLGELRGVSPDDVQIGLPVRATYLDFPAEGEDPAWTLYAWE
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK ANAALNPTAIYRDPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAV
Mvan_4171|M.vanbaalenii_PYR-1 ANAALNPTAIYRDPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVVSAV
MSMEG_4814|M.smegmatis_MC2_155 ANAALNPTAIYREPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAV
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 PDE-----------------------------------------------
Rv3542c|M.tuberculosis_H37Rv PDE-----------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 AA------------------------------------------------
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK DAAADAPKPPVFFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTRTSL
Mvan_4171|M.vanbaalenii_PYR-1 DAAVDLPKPPVYFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTRTSL
MSMEG_4814|M.smegmatis_MC2_155 DAARDLPRPPIRFEAVGTQIIERLDWDQTTLTHEPQVLGQSAHMWSRTSL
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK RPDDVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIP
Mvan_4171|M.vanbaalenii_PYR-1 RPADVDVAELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDGVIP
MSMEG_4814|M.smegmatis_MC2_155 RPSDVDVAELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIP
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1628|M.marinum_M --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
MAV_3934|M.avium_104 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK LNTHGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVADARVAVVSSGGLTP
Mvan_4171|M.vanbaalenii_PYR-1 LNTHGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVDGARVAVVSSGGLTP
MSMEG_4814|M.smegmatis_MC2_155 LNTHGGQLSHGRTHGMGLIHEAVTQLRGEAGERQVEDARVAVASSGGLTP
TH_4518|M.thermoresistible__bu --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1628|M.marinum_M ----------
MUL_3408|M.ulcerans_Agy99 ----------
MAV_3934|M.avium_104 ----------
Mflv_2483|M.gilvum_PYR-GCK SGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 SGALLLRTAT
MSMEG_4814|M.smegmatis_MC2_155 SGVLLLRRDD
TH_4518|M.thermoresistible__bu ----------
Mb3572c|M.bovis_AF2122/97 ----------
Rv3542c|M.tuberculosis_H37Rv ----------
MAB_0616|M.abscessus_ATCC_1997 ----------