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VNRRAFLALMAATGAAGAIRGASAPAHAGGDELRDLPEFSSANGVLDTELSAVTNVVELDGRQLTLETFN GQLPGPILRIRPGDNLRVLLKNRIVPVGIPTNNVFMLPYCASKSNDARYDTRRACVHDLWNKWERRQTLA QEDVDINLHTHGLQVSPEDPADNVFLQIGPLNDHQYSYDIPKDQPAGLYWYHPHFHTATAHQGWNGLSGA IIVEGDIDAVPEIAAMRERTIVINELWIADDSGEVPFTVVAPIAGDVPFASFPSVPSSMYYTVNGQLIPD ITMQPGEAQRFRVLNACPHRSIWLHVEGHSLEQIGTDGTPYAAPRTRQHIFLASANRAEFIIKAGEPGRY RIYAEAYDQGHPGGPRPYLPLATLVVRGKPTDTPMPKTLVEPPRMPNLPVSRRRVLVFSGDISGRTGMGI QFLIDGKEMNMDRIDQEVEGGTVEEWTIVNEDVFQHPLHIHINPFQVVDVQGIPAGDTSWAAAYEPDIWW DTFRLPPYGRYTLRTYFRPDVTGKTVYHCHILPHEDRGMMGILLVDPPGQYPKGAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1618 | cueO | - | 100% (546) | multicopper oxidase, type 1, CueO |
| M. marinum M | MMAR_4770 | - | 1e-08 | 23.30% (309) | oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3489 | - | 8e-05 | 26.44% (174) | multicopper oxidase, type 3 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0463c | - | 1e-16 | 23.59% (585) | oxidase (copper-binding protein) |
| M. avium 104 | MAV_3048 | - | 8e-07 | 20.50% (278) | multicopper oxidase family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0341 | - | 7e-09 | 23.30% (309) | oxidase |
| M. vanbaalenii PYR-1 | Mvan_3672 | - | 7e-15 | 23.18% (591) | multicopper oxidase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0341|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3672|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0463c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3048|M.avium_104 --------------------------------------------------
MMAR_1618|M.marinum_M --------------------------------------------------
Mflv_3489|M.gilvum_PYR-GCK MKRSSWHLRAGSVVLGWLVALVMAAIAHPYIALSNWLLIHLLGLGAASNA
MUL_0341|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3672|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0463c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3048|M.avium_104 --------------------------------------------------
MMAR_1618|M.marinum_M --------------------------------------------------
Mflv_3489|M.gilvum_PYR-GCK ILIWSRHFADALLRRSPDPPYPGQVIRLLAFNIGAVTVITGMLGGWWPVV
MUL_0341|M.ulcerans_Agy99 ----------MPVLPTGGHPFGSAQLSRRGFIGAGIAGG--LALAGCGHS
Mvan_3672|M.vanbaalenii_PYR-1 ---------------MNRQSVGTKILTRRTFLAATLAAST-AAMAACGKP
MAB_0463c|M.abscessus_ATCC_199 ------------------MAVSRSQWGRRGFLQLGAATAAAGVLAACGTR
MAV_3048|M.avium_104 ---------------------MMVAVTRRDFCKWGGIAA----LAACAG-
MMAR_1618|M.marinum_M -------------------------MNRRAFLALMAATGAAGAIRGASAP
Mflv_3489|M.gilvum_PYR-GCK LAGGVLVAAVAAVHAGDLMRFLRAALPARFSITVHYYVAAAACLAVGAGL
* . : .
MUL_0341|M.ulcerans_Agy99 QTTQTGET---AMADAIAAAERARPHTG-R--------------TVTASL
Mvan_3672|M.vanbaalenii_PYR-1 TSVNP-------ATDPIAVAEAARPHTG-R--------------TVTAAL
MAB_0463c|M.abscessus_ATCC_199 PVRGPSGQPVGPSSPRVGALEAVRRDGGGR--------------LVPVNL
MAV_3048|M.avium_104 ------------------------PPHGKA--------------DYTLRI
MMAR_1618|M.marinum_M AHAGG---------DELRDLPEFSSANG----------------VLDTEL
Mflv_3489|M.gilvum_PYR-GCK GVAMANSALPGILAERFRTAHAVLNLFGWVGLTVLGTLVTLWPTMLRTRM
* :
MUL_0341|M.ulcerans_Agy99 TPQQAQIDLGGPVVQTLAFGNTVPGPLIRAS-------------VGDEVV
Mvan_3672|M.vanbaalenii_PYR-1 TPGPADIDLGGPVARTLAYNNSVPGPLIRAN-------------VGDELA
MAB_0463c|M.abscessus_ATCC_199 AARPLQLDLAGTTVSTWGYGDQIPGPTIRAR-------------KGEVLR
MAV_3048|M.avium_104 ATGTVELAPG-RVVSTLTYNGQFPGPLLRFM-------------QGRRTW
MMAR_1618|M.marinum_M SAVTNVVELDGRQLTLETFNGQLPGPILRIR-------------PGDNLR
Mflv_3489|M.gilvum_PYR-GCK ADGVERAARRGLPALVLSVAVAVAGAILGSSRVVGVGALSFLTAVGFVLW
: ..*. : *
MUL_0341|M.ulcerans_Agy99 VAVSN-----RLDRTTSVHWHGIALRNDMDG---AEPAT-PNIGADQDFT
Mvan_3672|M.vanbaalenii_PYR-1 ISVTN-----GLDHPSSLHWHGIALRNDMDG---ATPAT-PNIDPSSTFT
MAB_0463c|M.abscessus_ATCC_199 VAVAN-----GLPAPTTVHWHGIALRNDMDG---VPDLTQPQIAAAGSFT
MAV_3048|M.avium_104 VDVYN-----DTDAPEQLHWHGQHIGADVDG---AAEEGTPYVPAHGMRR
MMAR_1618|M.marinum_M VLLKNRIVPVGIPTNNVFMLPYCASKSNDAR---YDTRRACVHDLWNKWE
Mflv_3489|M.gilvum_PYR-GCK PHIDEVRRKRPADFPTLSVLCGVVWLAGSLGYLSVGLLTAPNSMAAATVT
: : .
MUL_0341|M.ulcerans_Agy99 YRFSVPNAGTYWAHPHVGLEDDH------GLYLPFIVDDPTE---PNRYD
Mvan_3672|M.vanbaalenii_PYR-1 YRFSAPHPGTYWAHPHTGLDADY------GLYAPVIIDDAAE---PGRYD
MAB_0463c|M.abscessus_ATCC_199 YEFALAHAGTYWFHPHVGTQLDR------GLYAPLIVEDPDE---RADYD
MAV_3048|M.avium_104 ISFVPGPAGFRFYHTHVVPRADLSRGQYSGLVGPVHIASKDDD--AGAFD
MMAR_1618|M.marinum_M RRQTLAQEDVDINLHTHGLQVSPE-DPADNVFLQIGPLNDHQY--SYDIP
Mflv_3489|M.gilvum_PYR-GCK AAAGPALLAGFLVQVLFGSLAYLIPMVVGGRASALAATAELERGAPWRLS
. . :
MUL_0341|M.ulcerans_Agy99 AEWIVVLDDWTDGVGKS-PQQLFDAFVDPNKPRMQELPGSSTAPSTSTST
Mvan_3672|M.vanbaalenii_PYR-1 AEWIVVLDDWTDGIGSS-PQQLYDGLR----------------PVTGAG-
MAB_0463c|M.abscessus_ATCC_199 TELVVALDDWIDGTGTD-PDKVLAGLR-----------------------
MAV_3048|M.avium_104 QETFLTLKEFEPSLSRG-GDMAVDFLAG----------------------
MMAR_1618|M.marinum_M KDQPAGLYWYHPHFHTATAHQGWNGLSG--------------------AI
Mflv_3489|M.gilvum_PYR-GCK VANFGLLICVLPVPNLVRVAVSALVLVAYGAFLPLLVRAVWLAQRNTGVR
* :
MUL_0341|M.ulcerans_Agy99 TTTTTTPTTKTSTTTTTTGTSKTSPTTTTSATGKPDEESGEVGSSDLLGG
Mvan_3672|M.vanbaalenii_PYR-1 -----------GHSGGMPGMSGTP-----GMPGVPG--VGGVGASQLLGG
MAB_0463c|M.abscessus_ATCC_199 -------------DKGMPGMGHSMG----DMPGMSIG-SMGVSAQAPLGA
MAV_3048|M.avium_104 ----------------------------AQEPDLRERGESSMAASRGRGE
MMAR_1618|M.marinum_M IVEGDIDAVPEIAAMRERTIVINELWIADDSGEVPFTVVAPIAGDVPFAS
Mflv_3489|M.gilvum_PYR-GCK STPGRLDPPPLRQRLGIAAAGFGVVILTAAAGVAADPATLGIGSAPTVTA
:..
MUL_0341|M.ulcerans_Agy99 DAG-DIAYPYYLVNGRIPAAPTSFKAKPGQRIRIRIINVASDTAFRVALA
Mvan_3672|M.vanbaalenii_PYR-1 DAG-DVSYPFYLANGRIPAAPTTLTARPGQRIRMRIINAASDTAFRVALA
MAB_0463c|M.abscessus_ATCC_199 DGG-DVTYPYYLINGRVAADPQSVDYRPGTRVRLRIINAAGDSAFRVAIP
MAV_3048|M.avium_104 QPGYEVGYRAFAINGRMLGHGDPIRVRTGQLVLLHVLNAGATETRSLALP
MMAR_1618|M.marinum_M FPS-VPSSMYYTVNGQLIP---DITMQPGEAQRFRVLNACPHRSIWLHVE
Mflv_3489|M.gilvum_PYR-GCK APTGHTTEVRVRVDG-MRYVPDTITVPAGDRLRITFHNTGTDRHDLVLAN
:* : . .* : . *. :
MUL_0341|M.ulcerans_Agy99 GHTMTVTHTDGYPVIPTQ-VDALLIGMA-----ERYDVIVTAADGVFPLV
Mvan_3672|M.vanbaalenii_PYR-1 GHRMTVTHTDGFPVVPTE-VDALLIGMG-----ERYDALITTGDGVFPFV
MAB_0463c|M.abscessus_ATCC_199 GTPLTVTHTDGFPVQPRQ-TDALLIGMG-----ERIDAIITVGEVSVPLL
MAV_3048|M.avium_104 GHAFTVVALDGNPVPNRAPVPVLWLGAG-----ERVSALVSMTNPGVWVL
MMAR_1618|M.marinum_M GHSLEQIGTDGTPYAAPRTRQHIFLASA-----NRAEFIIKAGEPGRYRI
Mflv_3489|M.gilvum_PYR-GCK GARTDRVAPGVTAVLDAGVIGSDLAGWCSIAGHRQMGMTLTIKAIGTPPV
* . . . .: :. :
MUL_0341|M.ulcerans_Agy99 ASAEGKN------------ALARALL-STGSGTAPDPQFRPAELNKRVG-
Mvan_3672|M.vanbaalenii_PYR-1 ASAEGKN------------ALARALL-STGAGAAPDPTFMPPELQRRVG-
MAB_0463c|M.abscessus_ATCC_199 AAPYGKD------------GYAQLVLRSSGTPVSGSAAEAAAALPKLAAL
MAV_3048|M.avium_104 GDLSDDD------------REHGLGVVVEYAGRAGEPQWVPPPP---FTW
MMAR_1618|M.marinum_M YAEAYDQ------------GHP-----GGPRPYLPLATLVVRGKPTDTPM
Mflv_3489|M.gilvum_PYR-GCK SGHEHELPGHGPDPSLTATDIARSLGGRPGPGFAARDPKLSAAETAEHRV
.
MUL_0341|M.ulcerans_Agy99 TVEMFTATTAVNLGRPDPQMSLPITLGGTMAK----------------YD
Mvan_3672|M.vanbaalenii_PYR-1 TVGVFTAAPEAVLDVSRADVALSARLSGSMAS----------------YD
MAB_0463c|M.abscessus_ATCC_199 DTASLSATEEVTLAVGEPDITYDLRLAGPGNK----------------YS
MAV_3048|M.avium_104 DYRLFAGPHPAPVAPPDHTIDLLIEKRNAADNG--------------FNV
MMAR_1618|M.marinum_M PKTLVEPPRMPNLPVSRRRVLVFSGDISGRTGM--------------GIQ
Mflv_3489|M.gilvum_PYR-GCK TLTVSEVEREVSPGITQRLWTFGGSAPGPTLRGRVGDVFEITLINDGTIG
.
MUL_0341|M.ulcerans_Agy99 WTINGEPYSKTHP---LTVRLGERPTLMFDNPTMMYHPIHLHGHTFQMIK
Mvan_3672|M.vanbaalenii_PYR-1 WTINGRPFEDTVP---LTVMQGQKATLTFTNTTMMWHPMHLHGHTFQVIK
MAB_0463c|M.abscessus_ATCC_199 WTINEKTYNPAEG---LPVREGQRVRLRFINNSMMFHPMHLHGHTFAVRT
MAV_3048|M.avium_104 WTVNGTPFAMDSNQPVLDVERGRRYRLRLRNASDDLHPMHLHRHTFEITR
MMAR_1618|M.marinum_M FLIDGKEMNMDRID--QEVEGGTVEEWTIVNEDVFQHPLHIHINPFQVVD
Mflv_3489|M.gilvum_PYR-GCK HSIDFHAGSLAPDRPMRTIEPGAQLVYRFTATRAGVWLYHCATMPMSVHI
:: : * : * .: :
MUL_0341|M.ulcerans_Agy99 PDGTP------------GARKDTVIVLPG-------QQLRAVLVADNPGY
Mvan_3672|M.vanbaalenii_PYR-1 PDGTP------------GPRKDTVIVLPM-------QELTVALAADNPGV
MAB_0463c|M.abscessus_ATCC_199 ASGAY------------GARKDTVLVAPM-------QTVEVDFDADNPGQ
MAV_3048|M.avium_104 FAGTPT----------AGVRKDVAMLGGY-------QSMEIDFVADQPGL
MMAR_1618|M.marinum_M VQGIPAGDTSWAAAYEPDIWWDTFRLPPYGR-----YTLRTYFRPDVTGK
Mflv_3489|M.gilvum_PYR-GCK ANGMFGAVVIDPPDLSTVDREYLMVQSEFYLGADGGEVDADKVAADTPDL
* . .* ..
MUL_0341|M.ulcerans_Agy99 WVLHCHNSYHREAGMMTLLDYIF---------------------------
Mvan_3672|M.vanbaalenii_PYR-1 WMMHCHNTYHQEAGMMTSLNYSPQPGAAPSHGQRQ---------------
MAB_0463c|M.abscessus_ATCC_199 WLTHCHNIYHGEAGMMTVVSYRQ---------------------------
MAV_3048|M.avium_104 SLLHCHQQIHMDYGLMLLLNGV----------------------------
MMAR_1618|M.marinum_M TVYHCHILPHEDRGMMGILLVDPPGQYPKGAP------------------
Mflv_3489|M.gilvum_PYR-GCK VVFNGYAQQYDHAPLTARVGERVRIWVLAAGPNRGSAFHVVGGQFDTVWA
: : : : . : :
MUL_0341|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3672|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0463c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3048|M.avium_104 --------------------------------------------------
MMAR_1618|M.marinum_M --------------------------------------------------
Mflv_3489|M.gilvum_PYR-GCK EGAYRLRPGAGGSQTLGLFPAQGGFVELSFPEPGNYPFVSHAMVDAERGA
MUL_0341|M.ulcerans_Agy99 --------
Mvan_3672|M.vanbaalenii_PYR-1 --------
MAB_0463c|M.abscessus_ATCC_199 --------
MAV_3048|M.avium_104 --------
MMAR_1618|M.marinum_M --------
Mflv_3489|M.gilvum_PYR-GCK HGVIAVGN