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VTIRYAAPGRINLIGEHTDYNLGWALPIALPQRAVATFVPDHGDALTASSDLMDGAVRIPLDTVPGGMSG WAGYVAGVIWALRCAGHPVPGGAMSISSDVEIGSGLSSSAALECAVLGAITSAAGVEIDRIEQARLAQRA ENEYVGAPTGLLDQLAALFGAPATALLIDFRDLSLQAVQFDPDAHGVALLLIDSRARHRHAGGEYAARRA SCERAAKALHAPSLRDVAELSSLTAIGDPTDARRARHVLTENRRVHEFVAALRDCDFTAAGRIFTASHAS MRDDFEITTEHIDLIADAAVRAGALGARMTGGGFGGCVIALVAEAGVEAVIAAVHREVRGAGYPPPAISR AHAAAGAGPLRGNARS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0941 | galK | - | 100% (366) | galactokinase, GalK |
| M. marinum M | MMAR_3217 | erg12 | 1e-08 | 27.13% (247) | mevalonate kinase, Erg12 |
| M. marinum M | MMAR_3215 | - | 1e-08 | 25.73% (377) | phosphomevalonate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0636 | galK | 1e-140 | 71.03% (359) | galactokinase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0620 | galK | 1e-139 | 70.25% (363) | galactokinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4638 | - | 2e-67 | 40.66% (364) | galactokinase (GalK) |
| M. avium 104 | MAV_4564 | galK | 1e-144 | 72.45% (363) | galactokinase |
| M. smegmatis MC2 155 | MSMEG_3692 | galK | 1e-129 | 66.30% (359) | galactokinase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0692 | galK | 0.0 | 97.54% (366) | galactokinase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0636|M.bovis_AF2122/97 --MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITA
Rv0620|M.tuberculosis_H37Rv --MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITA
MMAR_0941|M.marinum_M --MTIRYAAPGRINLIGEHTDYNLGWALPIALPQRAVATFVPDHGDALTA
MUL_0692|M.ulcerans_Agy99 --MTIRYAAPGRINLIGEHTDYNLGWALPIALPQRAVATLVPDHGDALTA
MAV_4564|M.avium_104 --MTVRYAAPGRINLIGEHTDYNLGFALPIALPQRTVASFTPADDDAITV
MSMEG_3692|M.smegmatis_MC2_155 MGDTVTYAAPGRINLIGEHTDYNLGLALPIALPQRVVVRYQPDDSEAITV
MAB_4638|M.abscessus_ATCC_1997 --MTGTWSAPGRVNVIGEHTDYNGGLSLPIAIPQHVDCTLTPRDDQTVRV
* :.****:*:******** * :****:*::. * . :: .
Mb0636|M.bovis_AF2122/97 RSDRA-DGSARIPLDTTPG-QVTGWAAYAAGAIWALRGAGHPVPGGAMSI
Rv0620|M.tuberculosis_H37Rv RSDRA-DGSARIPLDTTPG-QVTGWAAYAAGAIWALRGAGHPVPGGAMSI
MMAR_0941|M.marinum_M SSDLM-DGAVRIPLDTVPG-GMSGWAGYVAGVIWALRCAGHPVPGGAMSI
MUL_0692|M.ulcerans_Agy99 SSDLM-DGAVRIPLDTVPG-GVSGWAGYVAGVIWALRCAGHPVSGGAISI
MAV_4564|M.avium_104 VSDRA-DAPVRIPIDTGPG-DVTGWAAYPAGVMWALRTAGHPVPGGAMSI
MSMEG_3692|M.smegmatis_MC2_155 SSAQE-SGDVVVPLDTTPG-DITGWAAYIAGVVWALRDRGHRVEGGRMSI
MAB_4638|M.abscessus_ATCC_1997 TSQQHGRDWVEVPLDRLAHTDIVSWARYPLGVVHEFVKRGNDIHGMDLRL
* . :*:* . : .** * *.: : *: : * : :
Mb0636|M.bovis_AF2122/97 TSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVG
Rv0620|M.tuberculosis_H37Rv TSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVG
MMAR_0941|M.marinum_M SSDVEIGSGLSSSAALECAVLGAITSAAGVEIDRIEQARLAQRAENEYVG
MUL_0692|M.ulcerans_Agy99 SSDVEIGSGLSSSAALECAVLGAITSAAGVEIDRIEQARLAQRAENEYVG
MAV_4564|M.avium_104 TSDVPMGSGLSSSAALECAVLGAISSAAGIRIDATEQARLAQRAENEYVG
MSMEG_3692|M.smegmatis_MC2_155 TSDVEMGSGLASSAALECAVLSALTHGS--DMDRVEQARIAQCAENVYVG
MAB_4638|M.abscessus_ATCC_1997 DGDVPVGAGLSSSAAVECAVAAAIRDTFATELSDSELVDITHRAENDFVG
.** :*:**:****: ** .*: :. * . ::: *** :**
Mb0636|M.bovis_AF2122/97 APTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRA
Rv0620|M.tuberculosis_H37Rv APTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRA
MMAR_0941|M.marinum_M APTGLLDQLAALFGAPATALLIDFRDLSLQAVQFDPDAHGVALLLIDSRA
MUL_0692|M.ulcerans_Agy99 APTGLLDQLAALFGAPATALLIDFRDLSVQAVQFDLDAHGVALLLIDSRA
MAV_4564|M.avium_104 APTGLLDQLAALYGRPAAAVLIDFADLAVTPVAFDPDAAGVALLLIDSRE
MSMEG_3692|M.smegmatis_MC2_155 APTGLMDQLASLFGEPGRAMLIDFRELSVHQVPFTPETAGLTLLVMNSRA
MAB_4638|M.abscessus_ATCC_1997 APTGLLDQSASILCTAGHALFLDAETGAHTQVPFDLAAAGLELVVIDTGT
*****:*: *:: . *:::* : * * : .: *:::::
Mb0636|M.bovis_AF2122/97 RHRHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARR
Rv0620|M.tuberculosis_H37Rv RHCHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARR
MMAR_0941|M.marinum_M RHRHAGGEYAARRASCERAAKALHAPSLRDVAEL--SSLTAIGDPTDARR
MUL_0692|M.ulcerans_Agy99 RHRHAGGEYAARRASCERAAKALHAPSLRDVAEL--SSLTAIGDPIDARH
MAV_4564|M.avium_104 RHTHAGGDYAARRLSCERAAADLSASSLRAAADRGCTDLAAVRDPVDARR
MSMEG_3692|M.smegmatis_MC2_155 PHRHAAGEYAARRASCERVAAALGVESLREVQDRGLDALDAVTDDEDFRR
MAB_4638|M.abscessus_ATCC_1997 RHNHVTSEYATRRQQCQTAASLLEVHSLSAVTDAG--VLDTVADPMLRAR
* *. .:** ** .*: .* * . ** . : * :: * :
Mb0636|M.bovis_AF2122/97 ARHVLTENQRVLDFAAALADS-DFTAAGQLLTASHESMREDFAITTERID
Rv0620|M.tuberculosis_H37Rv ARHVLTENQRVLDFAAALADS-DFTAAGQLLTASHESMREDFAITTERID
MMAR_0941|M.marinum_M ARHVLTENRRVHEFVAALRDC-DFTAAGRIFTASHASMRDDFEITTEHID
MUL_0692|M.ulcerans_Agy99 ARHVLTENRRVHEFVAALRDC-DFTAAGRIFTASHASMRDDFEITTEHID
MAV_4564|M.avium_104 ARHVLTENGRVIDCVAALNNS-DYTEAGRIFTASHASMRDDFGITTERID
MSMEG_3692|M.smegmatis_MC2_155 ARHILTENQRVLDVVAALEQS-DFATAGEILTASHASMRDDFEITTAHID
MAB_4638|M.abscessus_ATCC_1997 ARHVVTENARVREVVAILQSGRDPRSIGPILTRGHGSLRDDFAVSTPQLD
***::*** ** : .* * . * * ::* .* *:*:** ::* ::*
Mb0636|M.bovis_AF2122/97 LIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGY
Rv0620|M.tuberculosis_H37Rv LIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGY
MMAR_0941|M.marinum_M LIADAAVRAGALGARMTGGGFGGCVIALVAEAGVEAVIAAVHREVRGAGY
MUL_0692|M.ulcerans_Agy99 LIADAAVRAGALGARMTGGGFGGCVIALVVEAGVEAVIAAVHREVRGAGY
MAV_4564|M.avium_104 LIADTALRAGALGARMTGGGFGGCVIALAPVQRAEAIGQAVRRAATQAGF
MSMEG_3692|M.smegmatis_MC2_155 LIADTAVRAGALGARLTGGGFGGCVIALVPEDLADSVAETVRSTVVAAGH
MAB_4638|M.abscessus_ATCC_1997 AAVEASCDSGAHGARMTGGGFGGSVIALAEADSSARIGTAVAQHFSAQHW
.::: :** ***:*******.****. : :*
Mb0636|M.bovis_AF2122/97 DEPAVSRTYAAPGAAECC-----
Rv0620|M.tuberculosis_H37Rv DEPAVSRTYAAPGAAECR-----
MMAR_0941|M.marinum_M PPPAISRAHAAAGAGPLRGNARS
MUL_0692|M.ulcerans_Agy99 PPPAISRAHAAAGAGPLRGNARS
MAV_4564|M.avium_104 AQPVVTRTRAAAGAGPCR-----
MSMEG_3692|M.smegmatis_MC2_155 PEPTISRAQAAPGAGIV------
MAB_4638|M.abscessus_ATCC_1997 PIPQVFVVTPSDGARRIR-----
* : . .: **