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M. bovis AF2122 / 97 Mb0636 (galK)

annotation: galactokinase
coordinates: 713962 - 715053
length: 363

MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTG
WAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRA
ENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHRHAGGEYALRRA
SCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASH
ESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAV
SRTYAAPGAAECC
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0636galK-100% (363)galactokinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0620galK0.099.72% (362) galactokinase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4638-7e-6640.77% (363) galactokinase (GalK)
M. marinum MMMAR_0941galK1e-14071.03% (359) galactokinase, GalK
M. avium 104MAV_4564galK1e-14671.55% (362) galactokinase
M. smegmatis MC2 155MSMEG_3692galK1e-13166.48% (358) galactokinase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0692galK1e-13770.47% (359) galactokinase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0636|M.bovis_AF2122/97            --MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITA
Rv0620|M.tuberculosis_H37Rv         --MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITA
MMAR_0941|M.marinum_M               --MTIRYAAPGRINLIGEHTDYNLGWALPIALPQRAVATFVPDHGDALTA
MUL_0692|M.ulcerans_Agy99           --MTIRYAAPGRINLIGEHTDYNLGWALPIALPQRAVATLVPDHGDALTA
MAV_4564|M.avium_104                --MTVRYAAPGRINLIGEHTDYNLGFALPIALPQRTVASFTPADDDAITV
MSMEG_3692|M.smegmatis_MC2_155      MGDTVTYAAPGRINLIGEHTDYNLGLALPIALPQRVVVRYQPDDSEAITV
MAB_4638|M.abscessus_ATCC_1997      --MTGTWSAPGRVNVIGEHTDYNGGLSLPIAIPQHVDCTLTPRDDQTVRV
                                       *  :.****:*:******** * :****:*::.     * .  :: .

Mb0636|M.bovis_AF2122/97            RSDRA-DGSARIPLDTTPG-QVTGWAAYAAGAIWALRGAGHPVPGGAMSI
Rv0620|M.tuberculosis_H37Rv         RSDRA-DGSARIPLDTTPG-QVTGWAAYAAGAIWALRGAGHPVPGGAMSI
MMAR_0941|M.marinum_M               SSDLM-DGAVRIPLDTVPG-GMSGWAGYVAGVIWALRCAGHPVPGGAMSI
MUL_0692|M.ulcerans_Agy99           SSDLM-DGAVRIPLDTVPG-GVSGWAGYVAGVIWALRCAGHPVSGGAISI
MAV_4564|M.avium_104                VSDRA-DAPVRIPIDTGPG-DVTGWAAYPAGVMWALRTAGHPVPGGAMSI
MSMEG_3692|M.smegmatis_MC2_155      SSAQE-SGDVVVPLDTTPG-DITGWAAYIAGVVWALRDRGHRVEGGRMSI
MAB_4638|M.abscessus_ATCC_1997      TSQQHGRDWVEVPLDRLAHTDIVSWARYPLGVVHEFVKRGNDIHGMDLRL
                                     *       . :*:*  .   : .** *  *.:  :   *: : *  : :

Mb0636|M.bovis_AF2122/97            TSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVG
Rv0620|M.tuberculosis_H37Rv         TSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVG
MMAR_0941|M.marinum_M               SSDVEIGSGLSSSAALECAVLGAITSAAGVEIDRIEQARLAQRAENEYVG
MUL_0692|M.ulcerans_Agy99           SSDVEIGSGLSSSAALECAVLGAITSAAGVEIDRIEQARLAQRAENEYVG
MAV_4564|M.avium_104                TSDVPMGSGLSSSAALECAVLGAISSAAGIRIDATEQARLAQRAENEYVG
MSMEG_3692|M.smegmatis_MC2_155      TSDVEMGSGLASSAALECAVLSALTHGS--DMDRVEQARIAQCAENVYVG
MAB_4638|M.abscessus_ATCC_1997      DGDVPVGAGLSSSAAVECAVAAAIRDTFATELSDSELVDITHRAENDFVG
                                     .** :*:**:****:  ** .*:       :.  * . ::: *** :**

Mb0636|M.bovis_AF2122/97            APTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRA
Rv0620|M.tuberculosis_H37Rv         APTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRA
MMAR_0941|M.marinum_M               APTGLLDQLAALFGAPATALLIDFRDLSLQAVQFDPDAHGVALLLIDSRA
MUL_0692|M.ulcerans_Agy99           APTGLLDQLAALFGAPATALLIDFRDLSVQAVQFDLDAHGVALLLIDSRA
MAV_4564|M.avium_104                APTGLLDQLAALYGRPAAAVLIDFADLAVTPVAFDPDAAGVALLLIDSRE
MSMEG_3692|M.smegmatis_MC2_155      APTGLMDQLASLFGEPGRAMLIDFRELSVHQVPFTPETAGLTLLVMNSRA
MAB_4638|M.abscessus_ATCC_1997      APTGLLDQSASILCTAGHALFLDAETGAHTQVPFDLAAAGLELVVIDTGT
                                    *****:*: *::   .  *:::*    :   * *   : .: *:::::  

Mb0636|M.bovis_AF2122/97            RHRHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARR
Rv0620|M.tuberculosis_H37Rv         RHCHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARR
MMAR_0941|M.marinum_M               RHRHAGGEYAARRASCERAAKALHAPSLRDVAEL--SSLTAIGDPTDARR
MUL_0692|M.ulcerans_Agy99           RHRHAGGEYAARRASCERAAKALHAPSLRDVAEL--SSLTAIGDPIDARH
MAV_4564|M.avium_104                RHTHAGGDYAARRLSCERAAADLSASSLRAAADRGCTDLAAVRDPVDARR
MSMEG_3692|M.smegmatis_MC2_155      PHRHAAGEYAARRASCERVAAALGVESLREVQDRGLDALDAVTDDEDFRR
MAB_4638|M.abscessus_ATCC_1997      RHNHVTSEYATRRQQCQTAASLLEVHSLSAVTDAG--VLDTVADPMLRAR
                                     * *. .:** ** .*: .*  * . **  . :     * :: *     :

Mb0636|M.bovis_AF2122/97            ARHVLTENQRVLDFAAALADS-DFTAAGQLLTASHESMREDFAITTERID
Rv0620|M.tuberculosis_H37Rv         ARHVLTENQRVLDFAAALADS-DFTAAGQLLTASHESMREDFAITTERID
MMAR_0941|M.marinum_M               ARHVLTENRRVHEFVAALRDC-DFTAAGRIFTASHASMRDDFEITTEHID
MUL_0692|M.ulcerans_Agy99           ARHVLTENRRVHEFVAALRDC-DFTAAGRIFTASHASMRDDFEITTEHID
MAV_4564|M.avium_104                ARHVLTENGRVIDCVAALNNS-DYTEAGRIFTASHASMRDDFGITTERID
MSMEG_3692|M.smegmatis_MC2_155      ARHILTENQRVLDVVAALEQS-DFATAGEILTASHASMRDDFEITTAHID
MAB_4638|M.abscessus_ATCC_1997      ARHVVTENARVREVVAILQSGRDPRSIGPILTRGHGSLRDDFAVSTPQLD
                                    ***::*** ** : .* * .  *    * ::* .* *:*:** ::* ::*

Mb0636|M.bovis_AF2122/97            LIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGY
Rv0620|M.tuberculosis_H37Rv         LIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGY
MMAR_0941|M.marinum_M               LIADAAVRAGALGARMTGGGFGGCVIALVAEAGVEAVIAAVHREVRGAGY
MUL_0692|M.ulcerans_Agy99           LIADAAVRAGALGARMTGGGFGGCVIALVVEAGVEAVIAAVHREVRGAGY
MAV_4564|M.avium_104                LIADTALRAGALGARMTGGGFGGCVIALAPVQRAEAIGQAVRRAATQAGF
MSMEG_3692|M.smegmatis_MC2_155      LIADTAVRAGALGARLTGGGFGGCVIALVPEDLADSVAETVRSTVVAAGH
MAB_4638|M.abscessus_ATCC_1997      AAVEASCDSGAHGARMTGGGFGGSVIALAEADSSARIGTAVAQHFSAQHW
                                      .:::  :** ***:*******.****.       :  :*         

Mb0636|M.bovis_AF2122/97            DEPAVSRTYAAPGAAECC-----
Rv0620|M.tuberculosis_H37Rv         DEPAVSRTYAAPGAAECR-----
MMAR_0941|M.marinum_M               PPPAISRAHAAAGAGPLRGNARS
MUL_0692|M.ulcerans_Agy99           PPPAISRAHAAAGAGPLRGNARS
MAV_4564|M.avium_104                AQPVVTRTRAAAGAGPCR-----
MSMEG_3692|M.smegmatis_MC2_155      PEPTISRAQAAPGAGIV------
MAB_4638|M.abscessus_ATCC_1997      PIPQVFVVTPSDGARRIR-----
                                      * :  . .: **