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VDDGLGLRVNRRTFVGTSVAVGGAVAAVTAIPGSERVHQGDGHTAVVRLQINGEHREIAVDNRTSLLDML RERAGLPGTKKGCDQGACGSCTVLVDGRRINSCLALAVMHDGAQITTIEGLTGSAGPDGRLHPLQQAFID EDALQCGYCTPGQIMSGVACIAEGHAGSPAEIREWMSGNLCRCGAYPNIVKAVASVARDD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0834 | coxS_1 | - | 100% (200) | carbon monoxyde dehydrogenase (small chain), CoxS_1 |
| M. marinum M | MMAR_0082 | coxS_2 | 1e-53 | 62.25% (151) | carbon monoxyde dehydrogenase (small chain), CoxS_2 |
| M. marinum M | MMAR_0621 | coxS_3 | 3e-36 | 48.00% (150) | carbon monoxyde dehydrogenase (small chain), CoxS_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0381c | - | 1e-29 | 42.86% (147) | carbon monoxyde dehydrogenase small subunit |
| M. gilvum PYR-GCK | Mflv_0282 | - | 7e-46 | 53.53% (170) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0374c | - | 1e-29 | 42.86% (147) | carbon monoxyde dehydrogenase small subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 7e-21 | 36.49% (148) | xanthine dehydrogenase family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0872 | - | 6e-71 | 65.82% (196) | twin-arginine translocation pathway signal |
| M. thermoresistible (build 8) | TH_1272 | - | 1e-39 | 48.39% (155) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) |
| M. ulcerans Agy99 | MUL_4578 | coxS_1 | 1e-115 | 100.00% (200) | carbon monoxyde dehydrogenase (small chain), CoxS_1 |
| M. vanbaalenii PYR-1 | Mvan_2076 | - | 6e-39 | 48.57% (175) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------MDDGLGLRVNRRTFVGTSVAVGGAVAAVTAIPGSERVHQGDG
MUL_4578|M.ulcerans_Agy99 --------MDDGLGLRVNRRTFVGTSVAVGGAVAAVTAIPGSERVHQGDG
MSMEG_0872|M.smegmatis_MC2_155 MTTHETHDTAEALAWQIRRRTFIGASITVGGAMTLPLLASCSTEDVEPQA
Mflv_0282|M.gilvum_PYR-GCK -------------------------------------MSQ--------PL
Mvan_2076|M.vanbaalenii_PYR-1 -------------------------------------MTTGRTDVTVPPP
TH_1272|M.thermoresistible__bu -------------------------------------------------V
MAB_2925c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCV
Rv0374c|M.tuberculosis_H37Rv --MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCV
MMAR_0834|M.marinum_M HTAVVRLQINGEHREIAVDNRTSLLDMLRERAGLPGTKKGCDQGACGSCT
MUL_4578|M.ulcerans_Agy99 HTAVVRLQINGEHREIAVDNRTSLLDMLRERAGLPGTKKGCDQGACGSCT
MSMEG_0872|M.smegmatis_MC2_155 ESTTVRMSINGEQRVVDVDNRTSLLDMLRERVGLTGTKKGCDQGACGACT
Mflv_0282|M.gilvum_PYR-GCK HTSHIDLTVDGDQRSLDVDNRLTLLDALREKLGATAPKKGCDHGQCGSCT
Mvan_2076|M.vanbaalenii_PYR-1 PTRRIELTVNGVTRTVETDVRSTLLDLLREGLALTGTKKGCDHGLCGACT
TH_1272|M.thermoresistible__bu HDHQVELTVNGQRTSAPVESRLTLADFLRERCGLTGTHLGCEHGACGACT
MAB_2925c|M.abscessus_ATCC_199 ------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGDCGACT
: ::* * **: : **: . **:*.
Mb0381c|M.bovis_AF2122/97 VEVDGVPVKSCTMLAVMASGHSIRTVEGLAG---PDGQLDPVQEGFMRCH
Rv0374c|M.tuberculosis_H37Rv VEVDGVPVKSCTMLAVMASGHSIRTVEGLAG---PDGQLDPVQEGFMRCH
MMAR_0834|M.marinum_M VLVDGRRINSCLALAVMHDGAQITTIEGLTGSAGPDGRLHPLQQAFIDED
MUL_4578|M.ulcerans_Agy99 VLVDGRRINSCLALAVMHDGAQITTIEGLTGSAGPDGRLHPLQQAFIDED
MSMEG_0872|M.smegmatis_MC2_155 IHLNGERVVACLTLAVMHDGAEITTIEGLE----DNGRLHPLQQAFIDRD
Mflv_0282|M.gilvum_PYR-GCK VLVDGRRVTSCLTFAVAADGMRVTTAAGLG----DADTLHPVAQAFQDED
Mvan_2076|M.vanbaalenii_PYR-1 VEVDHERVLSCLTLAVSIDGAAVGTVEGFA----DGEHLDPLQQAFVDHD
TH_1272|M.thermoresistible__bu VIMDGAAVRSCLVFAVQADGSEVTTVEGIAS---PDGELSPVQQAMRDCH
MAB_2925c|M.abscessus_ATCC_199 VLVDGASQHSCIVPAHRVTDAEIHTVRSLAG----EHDLHPMQRGFIDHA
: :: :* * . : * .: * *: ..:
Mb0381c|M.bovis_AF2122/97 GLQCGFCTPGMLITARALLDRNPDP---------------------DEQT
Rv0374c|M.tuberculosis_H37Rv GLQCGFCTPGMLITARALLDRNPDP---------------------DEQT
MMAR_0834|M.marinum_M ALQCGYCTPGQIMSGVACIAEGHAG---------------------SPAE
MUL_4578|M.ulcerans_Agy99 ALQCGYCTPGQIMSGVACIAEGHAG---------------------SPAE
MSMEG_0872|M.smegmatis_MC2_155 ALQCGYCTPGQIMSGVACIREGHAN---------------------SPEE
Mflv_0282|M.gilvum_PYR-GCK AFQCGYCTPGQICSAVGMLDEVKSG---APSFVSDD---LDAPPELTADE
Mvan_2076|M.vanbaalenii_PYR-1 GFQCGYCTPGQLCSARAMLREHARGDLSAASFDPADRDVVDGPQHLSENE
TH_1272|M.thermoresistible__bu GLQCGFCTPGFVTTITAMLQENPDP---------------------TDEE
MAB_2925c|M.abscessus_ATCC_199 GFQCGFCTAGMVLTAATLTGDQTED-------------------------
.:***:**.* : :
Mb0381c|M.bovis_AF2122/97 IREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS---------------
Rv0374c|M.tuberculosis_H37Rv IREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS---------------
MMAR_0834|M.marinum_M IREWMSGNLCRCGAYPNIVKAVASVARDD---------------------
MUL_4578|M.ulcerans_Agy99 IREWMSGNLCRCGAYPNIVKAVASVARDD---------------------
MSMEG_0872|M.smegmatis_MC2_155 IRESMSGNICRCGAYVNIVGAVAAVARQGE--------------------
Mflv_0282|M.gilvum_PYR-GCK IRERMSGNLCRCAAYPNIVAAIGRAADR----------------------
Mvan_2076|M.vanbaalenii_PYR-1 IRERMAGNICRCGAYANIVAAISAVHGAS---------------------
TH_1272|M.thermoresistible__bu IREGLSGNFCRCTGYQGIIKAVRQAAEAMRA-------------------
MAB_2925c|M.abscessus_ATCC_199 LGNALKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPAAARVVTGTEPYTMD
: : : *::*** .* * :: .
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 ELPAGVGHVAVLGSPHPSARITRIDTDRARLLPGVRAVLCYRDDPGVPFS
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 TARHHERTDDPDDTLVFDRVLRFAGQRVAAVVADTPAIAHRALEHIDVEY
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 EVLPAVFDPEMAQLPGAHLVHGDKGLGARIADPARNLVAEVHGEVGDVAA
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 ALARARESGAVVTGSWQTARVQHVHLETHGSVGWQDERGRYVLRTSSQVP
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 FLVRDELCHVFGLAREQVRVFAPRVGGGFGAKQEMLTEDLVLLAVRVTGA
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PVVYEFTRSDQFTIAPCRHPMRVNVTAAADGDGVLTALAVDVLSDAGAYG
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NHSVGVMFHGCNESMAQYRCANKRVDAQAVYTNNIPSGAFRGYGLGQVLF
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 GIESALDELARNLGIDPFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QCLDLAQDALARGAADPARNGSDLPAGWKVGEGMAIAMIATVPPRGHVAD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 ARAELDARGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADT
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 DAVSHDTGAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVL
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 EPDGVRAGADLLGLTEIAASAPEPLSAVGHHEGTPRSVAFNVQAFRVAVR
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PQTGTVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALYEEILVHD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0834|M.marinum_M --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 GFVSTTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAKSMSESPYNPVA
Mb0381c|M.bovis_AF2122/97 --------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------
MMAR_0834|M.marinum_M --------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------
Mflv_0282|M.gilvum_PYR-GCK --------------------------------------
Mvan_2076|M.vanbaalenii_PYR-1 --------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PALANAIRDAVGVRVYRLPMNAARVWRVINDSGGGESS