For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SNVADTAPTFSRRLPIRVRINGEEVEAEVEARTTLLDWLRETLGLTGAKKGCNEGACGACTVLVDGTHMN SCLTLAVQCSGRDVTTVEGLVGPDGELHPVQQAFAEHDAFQCGYCTPGQIVSAVACIAEGYATDEISVRE WMSGNICRCSSYPQITSAVLAAANSSVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0082 | coxS_2 | - | 100% (169) | carbon monoxyde dehydrogenase (small chain), CoxS_2 |
| M. marinum M | MMAR_0834 | coxS_1 | 1e-53 | 62.25% (151) | carbon monoxyde dehydrogenase (small chain), CoxS_1 |
| M. marinum M | MMAR_0621 | coxS_3 | 1e-38 | 50.00% (148) | carbon monoxyde dehydrogenase (small chain), CoxS_3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0381c | - | 2e-36 | 45.51% (156) | carbon monoxyde dehydrogenase small subunit |
| M. gilvum PYR-GCK | Mflv_1570 | - | 9e-41 | 49.02% (153) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0374c | - | 2e-36 | 45.51% (156) | carbon monoxyde dehydrogenase small subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 1e-24 | 38.73% (142) | xanthine dehydrogenase family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0872 | - | 3e-47 | 58.11% (148) | twin-arginine translocation pathway signal |
| M. thermoresistible (build 8) | TH_1272 | - | 2e-40 | 49.33% (150) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) |
| M. ulcerans Agy99 | MUL_4578 | coxS_1 | 7e-54 | 62.25% (151) | carbon monoxyde dehydrogenase (small chain), CoxS_1 |
| M. vanbaalenii PYR-1 | Mvan_5186 | - | 5e-41 | 50.33% (153) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0872|M.smegmatis_MC2_155 MTTHETHDTAEALAWQIRRRTFIGASITVGGAMTLPLLASCSTEDVEPQA
MUL_4578|M.ulcerans_Agy99 --------MDDGLGLRVNRRTFVGTSVAVGGAVAAVTAIPGSERVHQGDG
MMAR_0082|M.marinum_M ------------------------MSNVADTAPTFSRRLP----------
Mflv_1570|M.gilvum_PYR-GCK -------------------------------MHEIP--------------
Mvan_5186|M.vanbaalenii_PYR-1 -------------------------------MHELP--------------
TH_1272|M.thermoresistible__bu -------------------------------VHDHQ--------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0872|M.smegmatis_MC2_155 ESTTVRMSINGEQRVVDVDNRTSLLDMLRERVGLTGTKKGCDQGACGACT
MUL_4578|M.ulcerans_Agy99 HTAVVRLQINGEHREIAVDNRTSLLDMLRERAGLPGTKKGCDQGACGSCT
MMAR_0082|M.marinum_M ----IRVRINGEEVEAEVEARTTLLDWLRETLGLTGAKKGCNEGACGACT
Mflv_1570|M.gilvum_PYR-GCK ----VEVSVNGRRYAATVEPRLTLADYLREKCGLTGTHLGCEHGACGACT
Mvan_5186|M.vanbaalenii_PYR-1 ----VEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTHLGCEHGACGACT
TH_1272|M.thermoresistible__bu ----VELTVNGQRTSAPVESRLTLADFLRERCGLTGTHLGCEHGACGACT
Mb0381c|M.bovis_AF2122/97 --MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCV
Rv0374c|M.tuberculosis_H37Rv --MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCV
MAB_2925c|M.abscessus_ATCC_199 ------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGDCGACT
: :**. * **: .: **: . **:*.
MSMEG_0872|M.smegmatis_MC2_155 IHLNGERVVACLTLAVMHDGAEITTIEGLE----DNGRLHPLQQAFIDRD
MUL_4578|M.ulcerans_Agy99 VLVDGRRINSCLALAVMHDGAQITTIEGLTGSAGPDGRLHPLQQAFIDED
MMAR_0082|M.marinum_M VLVDGTHMNSCLTLAVQCSGRDVTTVEGLVG---PDGELHPVQQAFAEHD
Mflv_1570|M.gilvum_PYR-GCK ALLDGQAVRACLVFAVQVDGQEVTTVEGIAG---ENGELSPVQAAMKECH
Mvan_5186|M.vanbaalenii_PYR-1 VLLDGQAVRSCLIFAVQVDGQEVTTVEGIAG---EDGELSPVQAAMRECH
TH_1272|M.thermoresistible__bu VIMDGAAVRSCLVFAVQADGSEVTTVEGIAS---PDGELSPVQQAMRDCH
Mb0381c|M.bovis_AF2122/97 VEVDGVPVKSCTMLAVMASGHSIRTVEGLAG---PDGQLDPVQEGFMRCH
Rv0374c|M.tuberculosis_H37Rv VEVDGVPVKSCTMLAVMASGHSIRTVEGLAG---PDGQLDPVQEGFMRCH
MAB_2925c|M.abscessus_ATCC_199 VLVDGASQHSCIVPAHRVTDAEIHTVRSLAG----EHDLHPMQRGFIDHA
::* :* * . .: *:..: : * *:* .:
MSMEG_0872|M.smegmatis_MC2_155 ALQCGYCTPGQIMSGVACIREGHANSPEEIRESMSGNICRCGAYVNIVGA
MUL_4578|M.ulcerans_Agy99 ALQCGYCTPGQIMSGVACIAEGHAGSPAEIREWMSGNLCRCGAYPNIVKA
MMAR_0082|M.marinum_M AFQCGYCTPGQIVSAVACIAEGYATDEISVREWMSGNICRCSSYPQITSA
Mflv_1570|M.gilvum_PYR-GCK GLQCGFCTPGFVTSITALLRDNPAPTDTEIREGLSGNFCRCTGYQGIVNA
Mvan_5186|M.vanbaalenii_PYR-1 GLQCGFCTPGFVTSITALLRDNPNPSDEEIREGLSGNFCRCTGYQGIVNA
TH_1272|M.thermoresistible__bu GLQCGFCTPGFVTTITAMLQENPDPTDEEIREGLSGNFCRCTGYQGIIKA
Mb0381c|M.bovis_AF2122/97 GLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRS
Rv0374c|M.tuberculosis_H37Rv GLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRS
MAB_2925c|M.abscessus_ATCC_199 GFQCGFCTAGMVLTAATLTG----DQTEDLGNALKGNLCRCTGYRPIRDA
.:***:**.* : : : : : :.*::*** .* * :
MSMEG_0872|M.smegmatis_MC2_155 VAAVARQGE-----------------------------------------
MUL_4578|M.ulcerans_Agy99 VASVARDD------------------------------------------
MMAR_0082|M.marinum_M VLAAANSSVR----------------------------------------
Mflv_1570|M.gilvum_PYR-GCK VKRAAETTG-----------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 VKRAAETTG-----------------------------------------
TH_1272|M.thermoresistible__bu VRQAAEAMRA----------------------------------------
Mb0381c|M.bovis_AF2122/97 IQWAAAHQTVKAQS------------------------------------
Rv0374c|M.tuberculosis_H37Rv IQWAAAHQTVKAQS------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VCGVVPPRGSVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARI
: ..
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 TRIDTDRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVL
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RFAGQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVH
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 GDKGLGARIADPARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARV
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QHVHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVF
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 APRVGGGFGAKQEMLTEDLVLLAVRVTGAPVVYEFTRSDQFTIAPCRHPM
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCA
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NKRVDAQAVYTNNIPSGAFRGYGLGQVLFGIESALDELARNLGIDPFEFR
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPARNG
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 SDLPAGWKVGEGMAIAMIATVPPRGHVADARAELDARGRYRISVGSAEFG
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAFGSAGTTVAGLA
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGADLLGLTEIAASA
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PEPLSAVGHHEGTPRSVAFNVQAFRVAVRPQTGTVRILQSVQTADAGVVV
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NPQQCRGQVEGGVAQAIGSALYEEILVHDGFVSTTALRNYHIPRLVDVPD
MSMEG_0872|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4578|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0082|M.marinum_M --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 TEVYFADTYDTFGPLGAKSMSESPYNPVAPALANAIRDAVGVRVYRLPMN
MSMEG_0872|M.smegmatis_MC2_155 -----------------
MUL_4578|M.ulcerans_Agy99 -----------------
MMAR_0082|M.marinum_M -----------------
Mflv_1570|M.gilvum_PYR-GCK -----------------
Mvan_5186|M.vanbaalenii_PYR-1 -----------------
TH_1272|M.thermoresistible__bu -----------------
Mb0381c|M.bovis_AF2122/97 -----------------
Rv0374c|M.tuberculosis_H37Rv -----------------
MAB_2925c|M.abscessus_ATCC_199 AARVWRVINDSGGGESS