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M. marinum M MMAR_0297 (ctpI)

annotation: cation-transporter ATPase I CtpI
coordinates: 337126 - 341988
length: 1620

KIPGVVNPVANLVAGVTGGAAQVVRAGVQTAADAAGVLQTLASPVVELAAPVVQSVAQTTNRAIGRNGAA
DRAPDGVTPPLRWHSGRRVHFDLDPLLPFPRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGAD
SDTVLDEVCDTAATVAADIFLSGSLSSPNSAPFADPGNPLAVLVPLTAAALDLAALGAAVTGWVIRLPAA
PQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAATTAAANGLTQAVGTPLLDLVQRGLQISEATAHRR
VWRDREPALASPGRPQAPVVPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAGPVE
SYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFAAVLGRGLASEGQLVLDPGALRRL
DRVQVVVIDGAALRGDHRAVLRAQGDEPGWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRG
PSATPAQGLEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVGSTHPPG
TPLLNLVRELRTDRGPVLLITALHRDFASTDTLAALAIADIGVALDDPRAATPWTADIITGTDLAAAVRI
LSAIPVARASSVSSVHLAQGGTTLAGLLLVTGEQAKTTNPASFRRWLNPVNTAAATALLSGSWSAATVLR
LPDPTPQPLTAWHALDPEIVYARLAGGARPMAVDPGTPTWRRLLDDLSYEPLVSPLRGPAHTLAQLAAAT
RHELADPLTPILAVGAAASAIVGSNVDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVVVP
AVATTRRRLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLEVDESLLTGESLPVDKQV
DPVAVNDADRASMLFEGSTIVAGRARAIVVATGAGTAAHRAISAVADVETSAGVQARLRELTSKVLPLTL
AGGASVSVLALMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTAHGALVRAPRTIEALGRV
DTVCFDKTGTLTENRLRVVCAIPSSTSPLDPFIDSADPRSTEVLRAAARATTQPHDGQGHAHATDEAIIV
AANSLEGLDDSAWTVIAEVPFESSRGYAASIGTTGTSNGHPTLMLKGAPETILPRCRFADPDADLEHAEA
LVHSLAERGLRVLAVAKRPWEHDTADDDDTDADAVDAAAHDLELLGYVGLADTARPSARPLIEALVDAQR
NVVLITGDHPITARAIARQLGLPEDVRVVTGAELIGLDEDACAKLAADVQVFARVSPEQKVQIVAALQRC
GRVTAMVGDGANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
LVGGNVGEVLFTIIGTAFGAGRAPVGTRQLLLVNLLTDMFPALAVAITSQYDDPEDDSDLSDEEIEEARR
RRQRAVLTAPTPSLDAPLMRQIANRGVVTAAGATAAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLTR
SHSPLVLATAFGSAGVLIGIIQTPVVSHFFGCTPLGPVAWTGVFSATAGATAVSVLAPKWLAKTVDVALE
HQDWASGSA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0297ctpI-100% (1620)cation-transporter ATPase I CtpI
M. marinum MMMAR_0740ctpH0.036.96% (1618) metal cation transporting p-type ATPase CtpH
M. marinum MMMAR_1228ctpH_10.035.74% (1606) metal cation transporting p-type ATPase CtpH_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0111cctpI0.085.86% (1613) cation-transporter ATPase I
M. gilvum PYR-GCKMflv_0956-1e-8331.16% (873) ATPase, P-type (transporting), HAD superfamily, subfamily IC
M. tuberculosis H37RvRv0107cctpI0.085.73% (1577) cation-transporter ATPase I
M. leprae Br4923MLBr_02671-0.081.67% (1615) putative cation transport ATPase
M. abscessus ATCC 19977MAB_0962-4e-4728.75% (647) cation-transporting ATPase E
M. avium 104MAV_5219-0.084.48% (1592) ATPase, P-type (transporting), HAD superfamily protein, subfamily
M. smegmatis MC2 155MSMEG_3926-3e-8730.40% (944) cation-transporting ATPase Pma1
M. thermoresistible (build 8)TH_2876-1e-17734.43% (1464) PUTATIVE ATPase, P-type (transporting), HAD superfamily,
M. ulcerans Agy99MUL_4826ctpI0.099.32% (1620) cation-transporter ATPase I CtpI
M. vanbaalenii PYR-1Mvan_1651-0.035.67% (1615) ATPase, P-type (transporting), HAD superfamily, subfamily IC

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               MKIPGVVNPVANLVAGVTGGAAQVVRAGVQTAADAAGVLQTLASPVVELA
MUL_4826|M.ulcerans_Agy99           MKIPGVVNPVANLVAGVTGGAVQMVRAGVQTAADAAGVLQTLASPVVELA
Mb0111c|M.bovis_AF2122/97           MKIPG----VATVLGGVTNGVAQTVRAGARLPGSAAAAVQTLASPVLELT
Rv0107c|M.tuberculosis_H37Rv        MKIPG----VATVLGGVTNGVAQTVRAGARLPGSAAAAVQTLASPVLELT
MAV_5219|M.avium_104                -----------------------MVRAGVSTAAGAAGALQTLASPVAELA
MLBr_02671|M.leprae_Br4923          MKIPHVTDPVSNMVG----GMAQVVRASTHAATGAVNTMQMLASPVAEFA
TH_2876|M.thermoresistible__bu      ------MGVLRSTVGGLIGASLRTLQVAAGTALLAGDTVIGAGRTVAGTV
Mvan_1651|M.vanbaalenii_PYR-1       ---------------------------------MVTDVASGAASTAR-AA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               APVVQSVAQTTNRAIGRNGAADRAPDGVTPPLRWHSGRRVHFDLDPLLPF
MUL_4826|M.ulcerans_Agy99           GPVVQSVAQTTNRAIGRNGAADGAPDGVTPPLRWHSGRRVHFDLDPLLPF
Mb0111c|M.bovis_AF2122/97           GPVVQSVVQTTGRAIGVRGSHNESPDGMTPPVRWRSGRRVHFDLDPLLPF
Rv0107c|M.tuberculosis_H37Rv        GPVVQSVVQTTGRAIGVRGSHNESPDGMTPPVRWRSGRRVHFDLDPLLPF
MAV_5219|M.avium_104                GPVIQSMAQTTGRAIGLDGSADGAP-AIVPPVRWHSGRRVHLDLDPLLPF
MLBr_02671|M.leprae_Br4923          WPVVQSVAKSTGRALG-TGHSPNFANRVDPPVRWHNGQRVHLDLDPLLPF
TH_2876|M.thermoresistible__bu      ADLAADVATGAESTAHTTLGLVVEALGGPPARRTSRNDSRHWIEVCGLSG
Mvan_1651|M.vanbaalenii_PYR-1       AGMVQDAAAGAPAAVQTAAAITTEALGGHPVKRSSRLNSHHWIEICGLSG
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               PRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGADSDTVLDEVC
MUL_4826|M.ulcerans_Agy99           PRWHEHAAVVEEPVRRIPGVAKAHVEGALGRLVVELEDGADSDTVLDEVC
Mb0111c|M.bovis_AF2122/97           PRWHEHAAMVEEPVRRIPGVAEAHVEGSLGRLVVELEPDVDSDIAVDEVR
Rv0107c|M.tuberculosis_H37Rv        PRWHEHAAMVEEPVRRIPGVAEAHVEGSLGRLVVELEPDADSDIAVDEVR
MAV_5219|M.avium_104                PRWHEYAPAVEEPVRRIPGVAKAHVEGSLGRLVVELADDADNAAVLDEVR
MLBr_02671|M.leprae_Br4923          PRWHEYAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGKVR
TH_2876|M.thermoresistible__bu      PDADAIAEEVVSALRAVPGVTDVAINHSMARAVVTVETGVPAADLTAVVA
Mvan_1651|M.vanbaalenii_PYR-1       PDADAIADEVLAAVHAVAGVRHAEINRSVARVIVTTEPEGPAENLAQVVA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               DTAATVAADIFLSGSLSSPNSAPFADPGNPLAVLVPLTAAALDLAALGAA
MUL_4826|M.ulcerans_Agy99           DTAATVAADIFLSGSASSPNSAPFADPGNPLAVLVPLTAAALDLAALGAA
Mb0111c|M.bovis_AF2122/97           DVVSAVAADIFLAGSVSSPNSAPFADPGNPLAILVPLTAAAMDLVAMGAT
Rv0107c|M.tuberculosis_H37Rv        DVVSAVAADIFLAGSVSSPNSAPFADPGNPLAILVPLTAAAMDLVAMGAT
MAV_5219|M.avium_104                STVASVAADISWSKAEAAPPSAPFADPGNPLAILVPLTAAALDLVAMGAA
MLBr_02671|M.leprae_Br4923          DVVIALAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALSAA
TH_2876|M.thermoresistible__bu      EAERRART------TEAG-RHRPHTLPWDDALLAARAVGAAAAAVGLGLS
Mvan_1651|M.vanbaalenii_PYR-1       DAERRVRT------GPCGDRHRPLTLPGDDALLAARTLGALAAVAGFGLS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               VTGWVIRLPAAPQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAATTA
MUL_4826|M.ulcerans_Agy99           VTGWVIRLPAAPQTTRAAAALINHQPRMVSLLESRLGRVGTDIALAATTA
Mb0111c|M.bovis_AF2122/97           VTGWVARLPAAPQTTRALAALINHQPRMVSLMESRLGRVGTDIALAATTA
Rv0107c|M.tuberculosis_H37Rv        VTGWVARLPAAPQTTRALAALINHQPRMVSLMESRLGRVGTDIALAATTA
MAV_5219|M.avium_104                VTGWVTRLPAAPQTTRAAAALINHQPRMVSILEARLGRVGTDIALAATTA
MLBr_02671|M.leprae_Br4923          VTGWVTRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSITTA
TH_2876|M.thermoresistible__bu      VTGNVLRFRGLPDFLSAIPTLADHNPGIHRQFERRLGREGTDLLFSLLTS
Mvan_1651|M.vanbaalenii_PYR-1       VTGNALRVPRVMELLAVVPTMAANVPQLRRQFEHRLGRDSTDLLLSLMNA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               AANGLTQAVGTPLLDLVQRGLQISEATAHRRVWRDREPALASPGRPQAPV
MUL_4826|M.ulcerans_Agy99           AANGLTQAVSTPLLDLVQRGLQISEATAHRRVWRDREPALASPGRPQAPV
Mb0111c|M.bovis_AF2122/97           AANGLTQSLGTPLLDLVQRSLQISEAAAHRRVWRDREPALASPRRPQAPV
Rv0107c|M.tuberculosis_H37Rv        AANGLTQSLGTPLLDLVQRSLQISEAAAHRRVWRDREPALASPRRPQAPV
MAV_5219|M.avium_104                AAHGLTQSFGTPLLDLTQRTLQISEAAAHRRVWRDREPQLASPDRPQAPV
MLBr_02671|M.leprae_Br4923          AASGLTQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQAPV
TH_2876|M.thermoresistible__bu      ASAAMTVSPTSAAAEMATRTMMVVEAVHTRRAWRRHEPRLVRHR------
Mvan_1651|M.vanbaalenii_PYR-1       AASALTASPTSAAAEAATRTLLAAEAWDARVAWRRHEPRLAAYP------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               VPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAGPV
MUL_4826|M.ulcerans_Agy99           VPVISSAGVQAQEPRHSWAAAAAGEASHVMVGGSIDAAIDTAKGSMAGPV
Mb0111c|M.bovis_AF2122/97           VPIISSAGAKSQEPRHSWAAAAAGEASHVVVGGSIDAAIDTAKGSRAGPV
Rv0107c|M.tuberculosis_H37Rv        VPIISSAGAKSQEPRHSWAAAAAGEASHVVVGGSIDAAIDTAKGSRAGPV
MAV_5219|M.avium_104                VPVISSA--KSEVPRHSWAAAAAGEASHVVVGGTIDAAMDKAKGSMAGPV
MLBr_02671|M.leprae_Br4923          VPVISSAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKGPV
TH_2876|M.thermoresistible__bu      -------------PSSRRPHRGTLEFG-------------------AGAG
Mvan_1651|M.vanbaalenii_PYR-1       -------------PEGGFPDRGTLEWD-------------------YGPS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               ESYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFAAV
MUL_4826|M.ulcerans_Agy99           ESYVNSAANGALIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFAAV
Mb0111c|M.bovis_AF2122/97           EQYVNQAANGSLIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFAAV
Rv0107c|M.tuberculosis_H37Rv        EQYVNQAANGSLIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQAFAAV
MAV_5219|M.avium_104                ESYVDSAANGSLIAAVSALVAGGGTEDAAAAIEAGVPRAAHMGRQAFAAV
MLBr_02671|M.leprae_Br4923          ESYVDSAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFAAT
TH_2876|M.thermoresistible__bu      ERYADRAVRMGVTAAAVVGAVSRNPTIGGAAALVTAPKPSRAAREAFGCA
Mvan_1651|M.vanbaalenii_PYR-1       ERYAERIGEAGLAAATIIGAVTRNPTIAASAALVTAPKPSRAARDAFGAA
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               LGRGLASE-GQLVLDPGALRRLDRVQVVVIDGAALRGDHRAVLRAQGDEP
MUL_4826|M.ulcerans_Agy99           LGRGLASE-GQLVLDPGALRRLDRVQVVVIDGAALRGDHRSVLRAQGDEP
Mb0111c|M.bovis_AF2122/97           LGRGLANT-GQLVLDPGALRRLDRVRVVVIDGAALRGDNRAVLHAQGDEP
Rv0107c|M.tuberculosis_H37Rv        LGRGLANT-GQLVLDPGALRRLDRVRVVVIDGAALRGDNRAVLHAQGDEP
MAV_5219|M.avium_104                LGRGLANS-GQLVLDPGALRRLDRVKVVVIDGAALRGDHRAVLRVRGEAP
MLBr_02671|M.leprae_Br4923          LGRGLANA-GQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGNTP
TH_2876|M.thermoresistible__bu      MTRGLITHHDALVVRPRALRALDRVDAVVIDPRVLYTDQLAVTRIVGVTN
Mvan_1651|M.vanbaalenii_PYR-1       MTRGLTNQHDVVVVRPRALRHLDRLDAIVIDPRALYTDKLTVTRIVGVTN
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               GWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRGPSATPAQG
MUL_4826|M.ulcerans_Agy99           GWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPLRGPSATPAQG
Mb0111c|M.bovis_AF2122/97           GWDDDRVYEVADALLHGEQAPEPDPDELPATGARLRWAPAQGPSATPAQG
Rv0107c|M.tuberculosis_H37Rv        GWDDDRVYEVADALLHGEQAPEPDPDELPATGARLRWAPAQGPSATPAQG
MAV_5219|M.avium_104                GWDDDRVYEVADALLHGEEAPEPDPDELPATGARLRWVPSQGPSAMPAQG
MLBr_02671|M.leprae_Br4923          GWDDDRVYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPVQG
TH_2876|M.thermoresistible__bu      SDRDRAWRAVQRALDRGGLTP----------------------------G
Mvan_1651|M.vanbaalenii_PYR-1       SRRTHAWEAVRAALDADSMSP----------------------------G
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               LEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTED
MUL_4826|M.ulcerans_Agy99           LEHADLVVDGQTVGNVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTED
Mb0111c|M.bovis_AF2122/97           LEHADLVVDGQCVGSVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTED
Rv0107c|M.tuberculosis_H37Rv        LEHADLVVDGQCVGSVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTED
MAV_5219|M.avium_104                LESADLIVDGDRVGRVDVGWEVDPYAIPLFQTAHRTGARVVLRHVAGTED
MLBr_02671|M.leprae_Br4923          REHADLVVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTED
TH_2876|M.thermoresistible__bu      WHPLSSIAGAPASGRILISPVRDQFAAAVVTEAHRCGRRVLSLDDDGLRS
Mvan_1651|M.vanbaalenii_PYR-1       WHKLSTIPGAGRAGKALVSPVRDPLANAVVTEARRTKPRVVSIADDGLRS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               LSASVGSTHPPGTPLLNLVRELRTDRGPVLLITALHRDFASTDTLAALAI
MUL_4826|M.ulcerans_Agy99           LSASVGSTHPPGTPLLNLVRELRTDPGPVLLITALHRDFASTDTLAALAI
Mb0111c|M.bovis_AF2122/97           LSASVGSTHPPGTPLLKLVRELRADRGPVLLITAVHRDFASTDTLAALAI
Rv0107c|M.tuberculosis_H37Rv        LSASVGSTHPPGTPLLKLVRELRADRGPVLLITAVHRDFASTDTLAALAI
MAV_5219|M.avium_104                LTASVGATHPPGTPLLNVVRELRADRGPVLLITALHRDFASTDTLAALAI
MLBr_02671|M.leprae_Br4923          LSASVGATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAALAI
TH_2876|M.thermoresistible__bu      LARGFDKLYPLGD----SVDESLAAAVAEAKADGATVALFTSPAMTAPHA
Mvan_1651|M.vanbaalenii_PYR-1       LAQGFDRLYPVDG----SIDEALAAAVDELKADGATVALLTTPDLSANQD
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_0297|M.marinum_M               ADIGVALDDPRAATPWTADIITGTDLAAAVRILSAIPVARASSVSSVHLA
MUL_4826|M.ulcerans_Agy99           ADIGVALDDPRAATPWTADIITGTDLAAAVRILSAIPVARASSVSSVHLA
Mb0111c|M.bovis_AF2122/97           ADVGVALDDPRGATPWTADLITGTDLAAAVRILSALPVARAASESAVHLA
Rv0107c|M.tuberculosis_H37Rv        ADVGVALDDPRGATPWTADLITGTDLAAAVRILSALPVARAASESAVHLA
MAV_5219|M.avium_104                ADVGVALDDPRAATAWTADIITGTDLADAVRILSAIPVARSASESAVHLA
MLBr_02671|M.leprae_Br4923          ADVGVALDDPHAATPWTADIITGTDLAAAVRILSALPVARSASESSVHLA
TH_2876|M.thermoresistible__bu      ADITIGLSPDGHPPPWGADVFVP-DLVSMWRILRALPAARSATTKGVRLS
Mvan_1651|M.vanbaalenii_PYR-1       ADLTIGLERPGWPPPWGADVFVP-DLLSVWRILHSLPTARAVTARGVRLS
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_3926|M.smegmatis_MC2_155      -------------------------------------------------M
MMAR_0297|M.marinum_M               QGGTTLAGLLLVTGEQ-AKTTNPASFRRWLNPVNTAAATALLSGSWSAAT
MUL_4826|M.ulcerans_Agy99           QGGTTLAGLLLVTGEQ-ARTTNPASFRRWLNPVNTAAATALLSGSWSAAT
Mb0111c|M.bovis_AF2122/97           QGGTTLAGLLLVTGEQ-DKTTNPASFRRWLNPVNAAAATALVSGMWSAAK
Rv0107c|M.tuberculosis_H37Rv        QGGTTLAGLLLVTGEQ-DKTTNPASFRRWLNPVNAAAATALVSGMWSAAK
MAV_5219|M.avium_104                QGGTTLAGLLLVTGEQ-EKGASPVSFRRWLNPVNAAAATALVAGTFSATR
MLBr_02671|M.leprae_Br4923          QGGTTLAGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVVSASK
TH_2876|M.thermoresistible__bu      ASSTAIGALMLIPGVT----------GNGPDSVNVGVAAGLWSGFRTATK
Mvan_1651|M.vanbaalenii_PYR-1       VSATTLGALMLIPGVP----------GSGPESVSVGVVGALWSGFTAGSK
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          -----------MSDWHARSVREVTDALDTDVTAGLTSEAAEERRHRHGPN
MSMEG_3926|M.smegmatis_MC2_155      RRPADAGGNSNENNWHTMQPDEVLDALGASR-SGLTDSEVERRRAVHGWN
MMAR_0297|M.marinum_M               VLRLPDPTPQPLTAWHALDPEIVYARLAGGARPMAVDPGTPTWRRLLDDL
MUL_4826|M.ulcerans_Agy99           VLRLPDPTPQPLTAWHALDPEIVYARLAGGARPMAVDPGTPTWRRLLDDL
Mb0111c|M.bovis_AF2122/97           VLRMPDPTPQPLTAWHALDPEIVYSRLAGGSRPLAVEPGIPAWRRILDDL
Rv0107c|M.tuberculosis_H37Rv        VLRMPDPTPQPLTAWHALDPEIVYSRLAGGSRPLAVEPGIPAWRRILDDL
MAV_5219|M.avium_104                VLRLPDPTPQPLTAWHALDPEIVYSRLAGGARPLAVET-EPSWRRRLDDL
MLBr_02671|M.leprae_Br4923          VLRLPDPTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRRRLDDL
TH_2876|M.thermoresistible__bu      VFDDSPPEPEPSHDWHALPADEVRRLLP---RPGDGDRQPPAGRDPALMR
Mvan_1651|M.vanbaalenii_PYR-1       VFRDPPPEPESVHDWHAMPVAEVERLLP---RPPD--EEPDVSTGLTDLP
MAB_0962|M.abscessus_ATCC_1997      -----------MATIEGLTISGLTAAEVAERVAQGKTNDVPSRAARSVSD
                                                   .      :         .                 

Mflv_0956|M.gilvum_PYR-GCK          QLTEAAA---------VPVWRKVLRLLADKMTLVLLVAAAVSAVVSREWE
MSMEG_3926|M.smegmatis_MC2_155      RLAAVRK---------QSALVPFIRQFHNVLIYVMSCAAIVTAVLQ-HWV
MMAR_0297|M.marinum_M               SYEPLVSPLRGPAHTLAQLAAATRHELADPLTPILAVGAAASAIVG-SNV
MUL_4826|M.ulcerans_Agy99           SYEPLVSPLRGPAHTLAQLAAATRHELADPLTPILAVGAAASAIVG-SNV
Mb0111c|M.bovis_AF2122/97           SYEPVMAPLRGPARTLAQLAVATRHELADPLTPILAVGAAASAIVG-SNI
Rv0107c|M.tuberculosis_H37Rv        SYEPVMAPLRGPARTLAQLAVATRHELADPLTPILAVGAAASAIVG-SNI
MAV_5219|M.avium_104                SYSPALAPLRAPLQNVLRLASATRTELADPLTPILAVGAAASAIVG-SNI
MLBr_02671|M.leprae_Br4923          SYTRALSPLRKPVTKLARLASATRQEFADPLTPILAVGAAASAIVG-SNI
TH_2876|M.thermoresistible__bu      PVRAAAAAMTWFWQLTRDFTAEMRSNLADPITPLLATGAVASALLG-SPL
Mvan_1651|M.vanbaalenii_PYR-1       PLRALSQAGTWSWHLTRDFVAEMRTNLSDPITPLLATGAVASALLG-SPL
MAB_0962|M.abscessus_ATCC_1997      IVR-------------ANVFTRINAILGVLLIIVLSTGSIINGAFG----
                                                              :   :  ::  .:  .. .     

Mflv_0956|M.gilvum_PYR-GCK          TPVVIMLVVTLNTVLNYVQEARAENSLQALRDMSISYSR-----------
MSMEG_3926|M.smegmatis_MC2_155      DAAVLFAAVLINVVIAYVQEGRAQAALDAIRAMMSPHAT-----------
MMAR_0297|M.marinum_M               DALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVVVPAVATTR
MUL_4826|M.ulcerans_Agy99           DALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQMVRRVVVPAVATTR
Mb0111c|M.bovis_AF2122/97           DALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTR
Rv0107c|M.tuberculosis_H37Rv        DALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTR
MAV_5219|M.avium_104                DALLVAGVMTVNAITGGAQRLRAESAAAELFAEQDQMVRRVVVPAVATTR
MLBr_02671|M.leprae_Br4923          DALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTR
TH_2876|M.thermoresistible__bu      DAALVGGVLLLNAALSAQQQLHAERILRRLMAVQEPSARRRVRMATATGT
Mvan_1651|M.vanbaalenii_PYR-1       DAALVGGVLLANAALSAEQQLHAERILQRLMAVEEPLARRRVG-------
MAB_0962|M.abscessus_ATCC_1997      ------LLIIANSAVGIIQELRAKQILDKLAIVGQTRPL-----------
                                            :  *      *. :*:     :                    

Mflv_0956|M.gilvum_PYR-GCK          --------VRRDGGEHRLPRTELVPGDVVLLEAGDAVPADGRIVSAARLQ
MSMEG_3926|M.smegmatis_MC2_155      --------VTRNGRTLDVEAVELVPGDVVQLAAGDRIPADLRLIGVDGLQ
MMAR_0297|M.marinum_M               R---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLE
MUL_4826|M.ulcerans_Agy99           R---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLE
Mb0111c|M.bovis_AF2122/97           R---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLE
Rv0107c|M.tuberculosis_H37Rv        R---RLEAARHATRTATVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLE
MAV_5219|M.avium_104                R---RLEAARHATRTATVSAKSLRPGDVIDLAAPEVVPADARLLEAEDLE
MLBr_02671|M.leprae_Br4923          R---RLEAAQHATRTVTVSAKSLRAGDVIDLAAPEVVPADARVLVAEDLE
TH_2876|M.thermoresistible__bu      GATGTEATPVEAGPIEEVPANRLRPGDVIEVRVGDVVPADARIMAASNVE
Mvan_1651|M.vanbaalenii_PYR-1       --------PLDQRRNERVSASRLRPGDIIEVHADEVVPADARLIEATNIE
MAB_0962|M.abscessus_ATCC_1997      --------VRRDGAATALAPNEVVLDDIIELGPGDQIVVDGEVIEESALE
                                                     :    :  .*:: :   : : .* .::    ::

Mflv_0956|M.gilvum_PYR-GCK          VAESALTGESAPVDKAVDGLDDTDLPLGDRTNMLYMNTEVTRGRATMVVT
MSMEG_3926|M.smegmatis_MC2_155      VDEAPLTGESAPVWKTIG-VDDEDTSLPDRRSMAYSGTLAIHGQATGVVV
MMAR_0297|M.marinum_M               VDESLLTGESLPVDKQVDPVAVN---DADRASMLFEGSTIVAGRARAIVV
MUL_4826|M.ulcerans_Agy99           VDESLLTGESLPVDKQVDPVAVN---DADRASMLFEGSTIVAGRARAIVV
Mb0111c|M.bovis_AF2122/97           VDESFLTGESLPVDKQVDPVAVN---DPDRASMLFEGSTIVAGHARAIVV
Rv0107c|M.tuberculosis_H37Rv        VDESFLTGESLPVDKQVDPVAVN---DPDRASMLFEGSTIVAGHARAIVV
MAV_5219|M.avium_104                VDESLLTGESLPVDKQVEPVAVN---DPDRASMLFEGSTIVAGHARAIVV
MLBr_02671|M.leprae_Br4923          VDESLLTGESLPVDKRVDPVAIN---DADRASMLFEGSAIVAGHARAIVV
TH_2876|M.thermoresistible__bu      VDESSLTGESLPVPKTAAATPGAP--LAERSGMLYAGTTMVAGTAVAVVT
Mvan_1651|M.vanbaalenii_PYR-1       VDESSLTGESLPVPKQTDPTPGAP--LAERACMLYAGSTLVAGTAVAVVT
MAB_0962|M.abscessus_ATCC_1997      IDESLLTGEADAIEKTIG-------------SQVLSGSFVVAGSGAYRAT
                                    : *: ****: .: *                     .:    * .   ..

Mflv_0956|M.gilvum_PYR-GCK          ATGMDTEVGAIATMLGTAGVSRTPLQQRIDNLAQMLTVVALLVVIVVTVL
MSMEG_3926|M.smegmatis_MC2_155      GTGAQTELGRINHLLTGVAPTATPLLRQISRFGRVLAVVILLLSAATYAL
MMAR_0297|M.marinum_M               ATGAGTAAHRAISAVADVETSAG-VQARLRELTSKVLPLTLAGGASVSVL
MUL_4826|M.ulcerans_Agy99           ATGAGTAAHRAISAVADVETSAG-VQARLRELTSKVLPLTLAGGASVSVL
Mb0111c|M.bovis_AF2122/97           ATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPMTLAGGAAVTAL
Rv0107c|M.tuberculosis_H37Rv        ATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPMTLAGGAAVTAL
MAV_5219|M.avium_104                ATGVGTAAHRAISAVADVETAAG-VQARLRELTSKVLPLTLAGGAAVSTL
MLBr_02671|M.leprae_Br4923          ATGVGTAAHRAISAVADVEVSAG-VQARLRELTSKVLPLTLAGGAAVTGL
TH_2876|M.thermoresistible__bu      AVGPRTEVRRALAMAAERPGEIG-LQRQLAHITKRALPFSVSSGALVGLL
Mvan_1651|M.vanbaalenii_PYR-1       TVGSRTEMRRALAMAPDKSREIG-LQRQLSRITKRALPFSVGGGALVGLL
MAB_0962|M.abscessus_ATCC_1997      KVGREAYAAKLAEEASKFTLVHSELRNGINKILQFITYLLLPAGALIIYT
                                     .*  :                  :   : .:      . :         

Mflv_0956|M.gilvum_PYR-GCK          G-LLRGDTWTELLLTAVSLAVATIPEGLTAVVAFTLAMGASRLARRGAII
MSMEG_3926|M.smegmatis_MC2_155      GVIWRGETLTEMFMMTVALAASAIPEGLPAIMTVTLAIGVQRMSRRRAIV
MMAR_0297|M.marinum_M               A-LMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTAHGALV
MUL_4826|M.ulcerans_Agy99           A-LMRRATLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTAHGALV
Mb0111c|M.bovis_AF2122/97           A-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTARGALV
Rv0107c|M.tuberculosis_H37Rv        A-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTARGALV
MAV_5219|M.avium_104                A-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLSAAQRLTARGALV
MLBr_02671|M.leprae_Br4923          A-LLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTAKGALV
TH_2876|M.thermoresistible__bu      S-VLRGTPIRAAVGSAVSLIVAAVPEGLPLVATLAQLASARRLSGESILI
Mvan_1651|M.vanbaalenii_PYR-1       S-LARGTPLREAVGSSVALTVAAVPEGLPLVATLAQLASARRLTGESVLI
MAB_0962|M.abscessus_ATCC_1997      QLFTTDDSWQESVLRMVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLV
                                      .    .    .   *.  .. :****  : :.:   .. *:  .  ::

Mflv_0956|M.gilvum_PYR-GCK          KQLSAVETLGSTADIATDKTGTLTLNEMTVRRLLLPGREFRVSGEGYSTD
MSMEG_3926|M.smegmatis_MC2_155      CRLPAVEALGSVTVICTDKTGTLTSNEMTVQRVVCGGHDIDVGGVGYAPV
MMAR_0297|M.marinum_M               RAPRTIEALGRVDTVCFDKTGTLTENRLRVVCAIPSSTSP-LDPF-----
MUL_4826|M.ulcerans_Agy99           RAPRTIEALGRVDTVCFDKTGTLTENRLRVVCAIPSSTSP-LDPF-----
Mb0111c|M.bovis_AF2122/97           RSPRTIEALGRVDTICFDKTGTLTENRLRVVCALPSSTAAERDPL-----
Rv0107c|M.tuberculosis_H37Rv        RSPRTIEALGRVDTICFDKTGTLTENRLRVVCALPSSTAAERDPL-----
MAV_5219|M.avium_104                RAPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPDDVNP-HDPF-----
MLBr_02671|M.leprae_Br4923          RSPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPNTRMP-HDPL-----
TH_2876|M.thermoresistible__bu      RNPNSIEALARLQVVCFDKTGTLSENRLQVKAVHP---------------
Mvan_1651|M.vanbaalenii_PYR-1       RNAQSIEAMARLQVVCFDKTGTLSENRLRVKAVRP---------------
MAB_0962|M.abscessus_ATCC_1997      QELPAIEGLARVDTVCADKTGTLTENGMRLADVHFPDR------------
                                        ::* :.    :. ******: * : :                    

Mflv_0956|M.gilvum_PYR-GCK          GKILVS----DGRPLPDLTAPLLAMALCSDASVREG----SLVGDPTEGA
MSMEG_3926|M.smegmatis_MC2_155      GDFSIDGRVIDPSRYPALMEALLAASLCNDASLDVEDEVWVITGDPTEAA
MMAR_0297|M.marinum_M               ------IDSADPRSTEVLRAAARATTQPHDG--------QGHAHATDEAI
MUL_4826|M.ulcerans_Agy99           ------IDSADPRSTEVLRAAARATTQPHDG--------QGHAHATDEAI
Mb0111c|M.bovis_AF2122/97           ------PQTTDAPSAEVLRAAARASTQPHNG--------EGHAHATDEAI
Rv0107c|M.tuberculosis_H37Rv        ------PQTTDAPSAEVLRAAARASTQPHNG--------EGHAHATDEAI
MAV_5219|M.avium_104                ------PELTAPQSAELVRAAARASARPQEG--------QGHAHATDEAI
MLBr_02671|M.leprae_Br4923          ------PDITDPHSAAVLRDAARASTQPHDG--------QGHTHATDEAI
TH_2876|M.thermoresistible__bu      ---------MRGRTETEVLEAALSTTFAEPG--------HRAHHATDEAI
Mvan_1651|M.vanbaalenii_PYR-1       ---------IDGFTEEQALDAALSTIFVRAG--------HRAHHATDDAI
MAB_0962|M.abscessus_ATCC_1997      ----------DGDEDALAVLAQLAADDPRPN-------------ASIAAI
                                                        .  :                     .  . 

Mflv_0956|M.gilvum_PYR-GCK          LVVLAEKGGVDVTGARAAIPRLAEVPFDSEYKYMATFCARSDLDGSGGH-
MSMEG_3926|M.smegmatis_MC2_155      LLVVAKKAGLDHDRETVSHPRVATVPFASENRIMGTLHS--DVDRTP---
MMAR_0297|M.marinum_M               IVAANSLEG----LDDSAWTVIAEVPFESSRGYAASIGTTGTSNGHPT--
MUL_4826|M.ulcerans_Agy99           IVAANSLEG----LNDSAWTVIAEVPFESSRGYAASIGTTGTSNGHPT--
Mb0111c|M.bovis_AF2122/97           LAAASALAGSLSSQGDSEWVVLAEVPFESSRGYAAAIGRVGT-DGIPM--
Rv0107c|M.tuberculosis_H37Rv        LAAASALAGSLSSQGDSEWVVLAEVPFESSRGYAAAIGRVGT-DGIPM--
MAV_5219|M.avium_104                LTAASSLNG----QRDSDWSMIAEVPFESSRGFAAAIGTVGNANGNPSDT
MLBr_02671|M.leprae_Br4923          LTAASSLNS----HTDSTWSLIAEVPFESSRGYAAAIGITGN-GKAPM--
TH_2876|M.thermoresistible__bu      IRAVNG------AAIAAPAQRDGFLPFQAGRPYAAAVRGTRL--------
Mvan_1651|M.vanbaalenii_PYR-1       RRAVHGDED---AADTTEIERDAFLPFQAGRPFAAAIVGTRL--------
MAB_0962|M.abscessus_ATCC_1997      AEAYDTPPG---------WETTAIAPFSSAKKWSGASYGEHG--------
                                      .                   .  ** :     .:              

Mflv_0956|M.gilvum_PYR-GCK          -RCFVKGAPGVLLEHAGSVLGEDGPRPIDPGYRQRIRERVEQLASEGLRT
MSMEG_3926|M.smegmatis_MC2_155      -LIVVKGAPERVLDICDSQRSPHGEEPLDRLYWQRMAA---TTAAQGLRV
MMAR_0297|M.marinum_M               --LMLKGAPETILPRCRFADPDADLEHAEALVHS--------LAERGLRV
MUL_4826|M.ulcerans_Agy99           --LMLKGAPETILPRCRFADPDADLEHAEALVHS--------LAERGLRV
Mb0111c|M.bovis_AF2122/97           --LMLKGAPETILPRCRLADPGVDHEHAESVVRH--------LAEQGLRV
Rv0107c|M.tuberculosis_H37Rv        --LMLKGAPETILPRCRLADPGVDHEHAESVVRH--------LAEQGLRV
MAV_5219|M.avium_104                PVLILKGAPEVILPRCRFADPEADQQRAEAVVRG--------LAEQGLRV
MLBr_02671|M.leprae_Br4923          --LMLKGAPEKILPRCRFADPEADVAHAESLVRH--------LAEQGLRV
TH_2876|M.thermoresistible__bu      ---TIKGAPEVLASALARGD-----SALTRRVEA--------MAAQGLRV
Mvan_1651|M.vanbaalenii_PYR-1       ---TIKGAPEVLASALAQAN-----GPAVAAIDD--------MAAKGLRV
MAB_0962|M.abscessus_ATCC_1997      --NWVIGAPDVLLDPA---------DAIATAAEE--------IGARGLRV
                                        : ***  :                               . .***.

Mflv_0956|M.gilvum_PYR-GCK          LMIAGRDIDHDLPADPDGLQTLVDD-----LTVYAVVGIVDPPRPEAGEA
MSMEG_3926|M.smegmatis_MC2_155      LAIARR-CGAPRNAGTLDIADLDSG-----FTMLGLVGIIDALRPEVAAA
MMAR_0297|M.marinum_M               LAVAKRPWEHDTADDDDTDADAVDAAAHD-LELLGYVGLADTARPSARPL
MUL_4826|M.ulcerans_Agy99           LAVAKRPWEHDTADDDDTDADAVDAAAHD-LELLGYVGLADTARPSARPL
Mb0111c|M.bovis_AF2122/97           LAVAQRTWDNGTTHDDETDADAVDAVAHD-LELIGYVGLADTARPSSRPL
Rv0107c|M.tuberculosis_H37Rv        LAVAQRTWDNGTTHDDETDADAVDAVAHD-LELIGYVGLADTARSSSRPL
MAV_5219|M.avium_104                LAVAQRGWKHDTD-DDDTDADAVDAAAHN-LELLGYVGLADTARASARPL
MLBr_02671|M.leprae_Br4923          LAVAQCSWGHDTTDDNDTDADAVDAAAHD-LELVGYIGLADTARPSSRPL
TH_2876|M.thermoresistible__bu      LAVAGRELSPEQAAAAVADPAVFTELCGSGLSLFGLIGLADTPRPSARGV
Mvan_1651|M.vanbaalenii_PYR-1       IAVAERQLTPEQAAAAAADAAAFEELCRSDLTPIGLLGLADTPRASAQDV
MAB_0962|M.abscessus_ATCC_1997      LLLASAELSVDDAHAPGAVTP------------RALVVLEQKIRPDARET
                                    : :*                              . : : :  *..    

Mflv_0956|M.gilvum_PYR-GCK          IATAHAAGITVHMITGDHLSTAAAVAHDLGIPG--AAASG-ADLDRLDDD
MSMEG_3926|M.smegmatis_MC2_155      VRECHRAGIRVKMITGDHAATAREIGAQLGIGIGKPAVIG-SEIASLNDT
MMAR_0297|M.marinum_M               IEALVDAQRNVVLITGDHPITARAIARQLGLPEDVR-VVTGAELIGLDED
MUL_4826|M.ulcerans_Agy99           IEALVDAQRNVVLITGDHPITARAIARQLGLPEDVR-VVTGAELIGLDED
Mb0111c|M.bovis_AF2122/97           IEALLDAERNVVLITGDHPITARAIARQLGLPADAR-VVTGAELAVLDEE
Rv0107c|M.tuberculosis_H37Rv        IEALLDAERNVVLITGDHPITARAIARQLGLPADAR-VVTGAELAVLDEE
MAV_5219|M.avium_104                IEALLDAERDVVLITGDHPITARAIARQLGLPADAR-VVTGAELAGLDED
MLBr_02671|M.leprae_Br4923          IEALVTAGRNVVLITGDHPITARAIAQQLGLRSDAR-VVNGTELIGLDED
TH_2876|M.thermoresistible__bu      LADLTERGIGVRLITGDHPVTAAVTARELGLDVDGEQVITGAEWETLSAE
Mvan_1651|M.vanbaalenii_PYR-1       LKELGNRGIGVRLITGDHPVTAMVIAGELGLDVTAEQVMTGAEWEGLSAE
MAB_0962|M.abscessus_ATCC_1997      LDYFASQHVSIKVISGDNAVSVSAVAQTLGLTG----AAVDARTLPTDTD
                                    :         : :*:**:  :.   .  **:      .   :     .  

Mflv_0956|M.gilvum_PYR-GCK          TLREQSPSFGVLARVAPEHKIRLVKALQSRGHVVAMTGDGVNDAPALKQA
MSMEG_3926|M.smegmatis_MC2_155      DLQTVVQERDIFARASPEHKLRLVRALQAGGEVVAMTGDGVNDSPALKKA
MMAR_0297|M.marinum_M               ACAKLAADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGANDAAAIRMA
MUL_4826|M.ulcerans_Agy99           ACAKLAADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGANDAAAIRMA
Mb0111c|M.bovis_AF2122/97           AHAKLAADMQVFARVSPEQKVQIVASLQRCGRVTAMVGDGANDAAAIRMA
Rv0107c|M.tuberculosis_H37Rv        AHAKLAADMQVFARVSPEQKVQIVAALQRCGRVTAMVGDGANDAAAIRMA
MAV_5219|M.avium_104                ACAKLVADVQVFARVSPEQKVQIVAALQRCGRVTAMVGDGANDAAAIRMA
MLBr_02671|M.leprae_Br4923          ACAELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGANDAAAIRMA
TH_2876|M.thermoresistible__bu      ERAAAVRSRSVFARMSPEHKIDVVQTLERNGVVTAMVGDGANDAAAIRAA
Mvan_1651|M.vanbaalenii_PYR-1       ERSEAVVSRIVYARMSPEHKIDVVQTLERIGMVTAMVGDGANDAAAIRAA
MAB_0962|M.abscessus_ATCC_1997      KLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKDA
                                           .    .*  *::*  :* :*:  * ..**.***.**  *:: *

Mflv_0956|M.gilvum_PYR-GCK          DIGIAMGITGTDVSKGAANMILTDDNFGTIVAAVREGRGIYANIIKFVKF
MSMEG_3926|M.smegmatis_MC2_155      DVGIAMGCRGTEAAKEAADMVLADDNFATIAAAVSEGRTVYDNIRKFVLF
MMAR_0297|M.marinum_M               DVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
MUL_4826|M.ulcerans_Agy99           DVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
Mb0111c|M.bovis_AF2122/97           DVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
Rv0107c|M.tuberculosis_H37Rv        DVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
MAV_5219|M.avium_104                DVGIGVSGRGSSAARGAADIVLTDQDLSVLLDALVEGRSMWAGVRDAVTI
MLBr_02671|M.leprae_Br4923          DVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTI
TH_2876|M.thermoresistible__bu      SVGVGVATRSSDPARTAADIVLLDGRIEALIDALDEGHHLWRRVQSAVSM
Mvan_1651|M.vanbaalenii_PYR-1       SVGFGVASRGSDPARTAADVVLLDGRIEALLDALDEGKQLWRRVQSAVSM
MAB_0962|M.abscessus_ATCC_1997      DIGVAMG-AGSSASRAVAQIVLLDNKFATLPYVVAEGRRVIGNIERVSNL
                                    .:*..:.  .:. :: .*:::* *  : .:  .: **: :   :     :

Mflv_0956|M.gilvum_PYR-GCK          QLTTAWGFVLIFLVCGSLGLAGGAPFTALQILWVNIIMDGPPALALGVDP
MSMEG_3926|M.smegmatis_MC2_155      MLPTNGGEALVVIAAILFQFT--LPLTPAQVLWINLVTSSTLGLALAFEP
MMAR_0297|M.marinum_M               LVGGNVGEVLFTIIGTAFGAG-RAPVGTRQLLLVNLLTDMFPALAVAITS
MUL_4826|M.ulcerans_Agy99           LVGGNVGEVLFTIIGTAFGAG-RAPVGTRQLLLVNLLTDMFPALAVAITS
Mb0111c|M.bovis_AF2122/97           LVGGNVGEVLFTVIGTAFGAG-RAPVGTRQLLLVNLLTDMFPALAVAVTS
Rv0107c|M.tuberculosis_H37Rv        LVGGNVGEVLFTVIGTAFGAG-RAPVGTRQLLLVNLLTDMFPALAVAVTS
MAV_5219|M.avium_104                LVGGNVGEVLFTIIGTAFGAG-RAPVGTRQLLLVNLLTDMFPALAVAVTS
MLBr_02671|M.leprae_Br4923          LVGGNVGEVVFTIIGTVFGAG-RAPVGTRQLLLVNLLTDMFPALSIAVTS
TH_2876|M.thermoresistible__bu      LLGGNSGEIAFALLTSLLTG--RSVLNARXXXTTAADAEPIPCKARAIPS
Mvan_1651|M.vanbaalenii_PYR-1       LLGGNTGEIAFALITSLLTG--RSVLNARQMLLVNMLTDALPAAALAVSR
MAB_0962|M.abscessus_ATCC_1997      FLTKTVYSVLLALTVGLAGLG-SKIFHYGAVPFPFQPIHVTIAAWFTIGI
                                     :        . :            .                     .  

Mflv_0956|M.gilvum_PYR-GCK          TEPDVMHQKPRPPTERLLNRARLQR----ILVLGMVMTLGTVTVLMLADD
MSMEG_3926|M.smegmatis_MC2_155      PEAGVMRRKPRAPSESLLSRHFAWR----VLLVSVLMAGGALGMFLWE--
MMAR_0297|M.marinum_M               QYDDPEDDSDLSDEEIEEARRRRQR----AVLTAPTPSLDAPLMRQIANR
MUL_4826|M.ulcerans_Agy99           QYDDPEDDSDLSDEEIEEARRRRQR----AVLTAPTPSLDAPLMRQIANR
Mb0111c|M.bovis_AF2122/97           QFAEPDDAEYPTDDAAERAQREHRR----AVLIGPTPSLDAPLLRQIVNR
Rv0107c|M.tuberculosis_H37Rv        QFAEPDDAEYPTDDAAERAQREHRR----AVLIGPTPSLDAPLLRQIVNR
MAV_5219|M.avium_104                QYVEPDEAEYPSAADAEAARREHRR----AVLTGPTPSLDAPLMRQIVTR
MLBr_02671|M.leprae_Br4923          QYEEPGEDEYQTDEEADEARRTHQH----EVLTGPTPSLDAPLMRQIVNR
TH_2876|M.thermoresistible__bu      MVMSGATAHSTDASMCTAIPAISGRRRPNESDRGPTTSWPSASPTSVPVN
Mvan_1651|M.vanbaalenii_PYR-1       QTDTTGQVDLDEAAMWRAIGVRG-----AATTVGATSAWAMASMTGTPQR
MAB_0962|M.abscessus_ATCC_1997      PAFILSLAPNNERAQTGFVRRVMLS----AIPSGLTVGIATFLSYLLARQ
                                                                     .                

Mflv_0956|M.gilvum_PYR-GCK          L-------FPESAGDPLFATTLAFTTFVFYQVFNLLNVRSDTGSAFSRQ-
MSMEG_3926|M.smegmatis_MC2_155      ---------LRSGTSVETARTMAVNAIVAAEMFYLLNNRFLLEPVLNRIG
MMAR_0297|M.marinum_M               G------VVTAAGATAAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLT
MUL_4826|M.ulcerans_Agy99           G------VVTAAGATAAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLT
Mb0111c|M.bovis_AF2122/97           G------VVTAAGATAAWAIGRWTPGTERRTATMGLTALVMTQLAQTLLT
Rv0107c|M.tuberculosis_H37Rv        G------VVTAAGATAAWAIGRWTPGTERRTATMGLTALVMTQLAQTLLT
MAV_5219|M.avium_104                G------AVTAAGATAAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLT
MLBr_02671|M.leprae_Br4923          G------VVTAAGATTAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLT
TH_2876|M.thermoresistible__bu      VSCATDDDTFSSSAIRGSAGRYMSMVSGPRVISAPSIRIMRVRLGIPLGV
Mvan_1651|M.vanbaalenii_PYR-1       A---------STVALIG----LVSTQLAQTLIDSRSPLVVATALGS----
MAB_0962|M.abscessus_ATCC_1997      I---------------LHVSGNSTQASTAALITELVAAVWVLAVVARPYQ
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          TFTNGAIWVSLAAVIVLQVLVVQLDVLQNLFDTTELT---------SAQW
MSMEG_3926|M.smegmatis_MC2_155      LFGNKIAFATVVACTALQLVFTYAPAMNAVFGSTPLG---------YVDW
MMAR_0297|M.marinum_M               RSHSPLVLATAFGSAGVLIGIIQTPVVSHFFGCTPLG---------PVAW
MUL_4826|M.ulcerans_Agy99           RSHSPLVLATAFGSAGVLIGIIQTPVVSHFFGCTPLG---------PVAW
Mb0111c|M.bovis_AF2122/97           RRHSPLVIATALGSAGVLVGIIQTPVISHFFGCTPLG---------PVAW
Rv0107c|M.tuberculosis_H37Rv        RRHSPLVIATALGSAGVLVGIIQTPVISHFSGVPRWDR--------SPGR
MAV_5219|M.avium_104                RRHSPLVVATALGSAGVLVGIVQTPVLSQFFGCTPLG---------PVAW
MLBr_02671|M.leprae_Br4923          RRHSPLVVATALGSAGVLIGIIQTPVISQFFGCTPLG---------PIAW
TH_2876|M.thermoresistible__bu      RGDVRSERATAFDSATEVLSDANHLFCSRTRGFGARVVAHIGGTRQALAW
Mvan_1651|M.vanbaalenii_PYR-1       -----------FATLAGVISTP-----GVSQVFGCTPVGPVG-------W
MAB_0962|M.abscessus_ATCC_1997      WWRVALVALSGLGYVAIFAIPLARKAFMLDPGNLAVTG---------PAL
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          LFAIAVGSSVLVVDEIGK--------------------------------
MSMEG_3926|M.smegmatis_MC2_155      IKAAAVGAPVFGVVELEK--------------------------------
MMAR_0297|M.marinum_M               TGVFSATAGATAVSVLAP--------------------------------
MUL_4826|M.ulcerans_Agy99           TGVFSATAGATAVSALAP--------------------------------
Mb0111c|M.bovis_AF2122/97           TGVFSATAGATAVSALAP--------------------------------
Rv0107c|M.tuberculosis_H37Rv        ASSAPRQEPPQSQRWHRS--------------------------------
MAV_5219|M.avium_104                TGVLGSTAGATAISALAP--------------------------------
MLBr_02671|M.leprae_Br4923          SGVITATAGATAVSVLAP--------------------------------
TH_2876|M.thermoresistible__bu      AQPLRHREAAAHERMVPREGPVGRDTRHSIRWGVRWGVRWGARSGGGGAG
Mvan_1651|M.vanbaalenii_PYR-1       GQAFSATAVAALLSATAPELLN----------------------------
MAB_0962|M.abscessus_ATCC_1997      GIGIAAAAVIEAVWWLQG--------------------------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          -----------------AVVRTARRRRRRRVSGADRPREARPASGR----
MSMEG_3926|M.smegmatis_MC2_155      -----------------FMVR---RRKARAALAGEEPKGGHTAAHR----
MMAR_0297|M.marinum_M               --------------------KWLAKTVDVALEHQDWASGSA---------
MUL_4826|M.ulcerans_Agy99           --------------------KWLAKTVDVALEHQDWASGSA---------
Mb0111c|M.bovis_AF2122/97           --------------------KWLASTVGVVQPDERPDDAEDSDAGG----
Rv0107c|M.tuberculosis_H37Rv        --------------------GWQAQSVSCNLMNALTTRKTLTRVDRTYRR
MAV_5219|M.avium_104                --------------------NWLAKQVAALEPGQQDA-------------
MLBr_02671|M.leprae_Br4923          --------------------QWLNKAFGIAQLNQE---------------
TH_2876|M.thermoresistible__bu      ADRDHRTRLPGAGPRGARLRRPVAQQVPRRLPGQDRHQAGETLSGDRGGQ
Mvan_1651|M.vanbaalenii_PYR-1       --------------RATDAVRKRVADVVESVPVVDDDDAGLDEDGVEGAD
MAB_0962|M.abscessus_ATCC_1997      --------------------KWSGQPRHFWATGDD---------------
                                                                                      

Mflv_0956|M.gilvum_PYR-GCK          ------------------------
MSMEG_3926|M.smegmatis_MC2_155      ------------------------
MMAR_0297|M.marinum_M               ------------------------
MUL_4826|M.ulcerans_Agy99           ------------------------
Mb0111c|M.bovis_AF2122/97           ------------------------
Rv0107c|M.tuberculosis_H37Rv        PR----------------------
MAV_5219|M.avium_104                ------------------------
MLBr_02671|M.leprae_Br4923          ------------------------
TH_2876|M.thermoresistible__bu      RGGGRFHRRRAGRGHIGRALGGDR
Mvan_1651|M.vanbaalenii_PYR-1       R------RRQQ------MDTGGD-
MAB_0962|M.abscessus_ATCC_1997      ------------------------