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MALPPPGKDRAAIVTGASSGIGEEFARILSQRGYQVVLVARSADRLEALAGRLGSDTHPLPADLSVRSDR AGLVDRVAALGLVPDILINNAGLSTLGPVAKSVPEQELNLVEVDVAAVVDLCSRFLPAMVERGRGAVLNV ASVAGFAPLPGQAAYGAAKAFVLSYTHSLRGELHGSGVSVTALSPGPVDTSFGDVAGFTQQETESLPKIM WKSVDQVAQAGIDGLAAGKAVVVPGLANRISAELIRVTPPDWMGSIMARIHPAMKRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0254 | - | - | 100% (267) | ketoacyl reductase |
| M. marinum M | MMAR_2367 | - | 1e-47 | 43.48% (253) | ketoacyl reductase |
| M. marinum M | MMAR_3856 | - | 6e-43 | 40.94% (254) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1571 | - | 7e-45 | 41.90% (253) | ketoacyl reductase |
| M. gilvum PYR-GCK | Mflv_0138 | - | 1e-65 | 48.89% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1544 | - | 7e-45 | 41.90% (253) | ketoacyl reductase |
| M. leprae Br4923 | MLBr_00429 | - | 2e-42 | 38.49% (265) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4261c | - | 8e-43 | 42.15% (242) | putative short chain dehydrogenase/reductase |
| M. avium 104 | MAV_3226 | - | 9e-44 | 41.50% (253) | ketoacyl reductase |
| M. smegmatis MC2 155 | MSMEG_4722 | - | 6e-37 | 39.09% (243) | short-chain dehydrogenase |
| M. thermoresistible (build 8) | TH_1383 | - | 3e-39 | 39.75% (244) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4860 | - | 1e-146 | 98.50% (267) | ketoacyl reductase |
| M. vanbaalenii PYR-1 | Mvan_3113 | - | 9e-47 | 43.87% (253) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0254|M.marinum_M MALPPPGKDRAAIVTGASSGIGEEFARILSQRGYQVVLVARSADRLEALA
MUL_4860|M.ulcerans_Agy99 MALPPPGKDRAAIVTGASSGIGEEFARILSQRGYQVVLVARSADRLEALA
Mflv_0138|M.gilvum_PYR-GCK MGLPTPSPTTTAVVTGASSGIGADLARELAARGHGVTLVARREDRLRALA
Mb1571|M.bovis_AF2122/97 MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELA
Rv1544|M.tuberculosis_H37Rv MSLPKPNNQTTVVITGASSGIGVELARGLAGRGFPLMLVARRRERLDELA
MAV_3226|M.avium_104 MSLPKPDIATTVVITGASSGIGAELARGLARRGFPLLLVARRRERLDDLA
Mvan_3113|M.vanbaalenii_PYR-1 MSLAKPSAGTTVVITGASSGIGEHIARGLARRGYSLTLIARRRDRLEALS
MAB_4261c|M.abscessus_ATCC_199 MAATN-SARPVALITGPTSGLGGGFARKYASQGYDVVLVARDEQRLGALA
MSMEG_4722|M.smegmatis_MC2_155 MPVPAPSPDARAVVTGASQNIGEALATELAARGHHLIITARREEVLTSLA
TH_1383|M.thermoresistible__bu MPVPEPTPDARAVITGASQNIGAALATELAARGHNLIVTARRAEVLTELA
MLBr_00429|M.leprae_Br4923 MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLA
* . .::**.:..:* :* : :*. : : ** : * *:
MMAR_0254|M.marinum_M GRLGS----DTHPLPADLSVRSDRAGLVDRVAALGLVPDILINNAGLSTL
MUL_4860|M.ulcerans_Agy99 GRLGS----DTHPLPADLSVRSDRAGLVDRVAALGLVPDILINNAGLSTL
Mflv_0138|M.gilvum_PYR-GCK DELSSSN-VRVEVVACDVADADARAGLFPEIERRGLTVDVLVNNAGIGTI
Mb1571|M.bovis_AF2122/97 DQLRQEHCVGVEVLPLDLADTQARAQLADRL--RSDAIAGLCNSAGFGTS
Rv1544|M.tuberculosis_H37Rv DQLRQEHCVGVEVLPLDLADTQARAQLADRL--RSDAIAGLCNSAGFGTS
MAV_3226|M.avium_104 NEVGGQYSVGVEVLPLDLGDSKARARLAGRL--RSESIAGLCNSAGFGTS
Mvan_3113|M.vanbaalenii_PYR-1 DELCRARSISVDVVALDLNEQSARAEAVERL--RSGAVAGLVNSAGFGTN
MAB_4261c|M.abscessus_ATCC_199 DELTCRFGVYAEALPADLADAADRARVADRL--AAG-VSVLVNNAGFATA
MSMEG_4722|M.smegmatis_MC2_155 QRLTERYGVTVEVRAVDLTDPAARATLCDEL--AEREISILCANAGTATF
TH_1383|M.thermoresistible__bu DRLTDRHGVTVEVRPLDLADPEQRGTLCAEL--AEREISILCANAGVATF
MLBr_00429|M.leprae_Br4923 ARLADKYRVAVEVRPADLTDPSERVKLADEL--TVRPISILCANAGTATF
.: .. . *: * .: * .** .*
MMAR_0254|M.marinum_M GPVAKSVPEQELNLVEVDVAAVVDLCSRFLPAMVERGRGAVLNVASVAGF
MUL_4860|M.ulcerans_Agy99 GPVAKSVPEQEFNLAEVDVAAVVDLCSRFLPAMVERGRGAVFNVASVAGF
Mflv_0138|M.gilvum_PYR-GCK GPVVDSTPEAEIGQVRVNVEAVIDLTTRAVQQMVPRGRGAILNVGSTAGF
Mb1571|M.bovis_AF2122/97 GRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGF
Rv1544|M.tuberculosis_H37Rv GRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGF
MAV_3226|M.avium_104 GVFHELPMERESEEVTLNALALMELTHATLPGMVSRGAGAVLNIASIAGF
Mvan_3113|M.vanbaalenii_PYR-1 GLLQDLPPDRERDQVIVNVLALTELTHAVLPQMVERGAGAVLNIGSIAGF
MAB_4261c|M.abscessus_ATCC_199 GEFWTAAPELLHSQLDVNVTAVMELTRAALPSMIEAGAGTVINVASVAGL
MSMEG_4722|M.smegmatis_MC2_155 GAVKDLDPAGEKAQVQLNVLGVHDLVLAVLPGMVARRAGGILISGSAAGN
TH_1383|M.thermoresistible__bu GPVHKLDPAEEKAQVQLNVLGVHDLVLAVLPGMVQRRAGGILISGSAAGN
MLBr_00429|M.leprae_Br4923 GPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGN
* . ::. .: :* : *: * :: .* **
MMAR_0254|M.marinum_M APLPGQAAYGAAKAFVLSYTHSLRGELHGSGVSVTALSPGPVDTSFGDVA
MUL_4860|M.ulcerans_Agy99 APLPGQAAYGAAKAFVLSYTHSLRGELHGSGVSVTALSPGPVDTSFGDVA
Mflv_0138|M.gilvum_PYR-GCK QPFPGQSGYAATKAFVRTYTDGLRGELAGTGVTVTALHPGPVRTEFLDTA
Mb1571|M.bovis_AF2122/97 QPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIA
Rv1544|M.tuberculosis_H37Rv QPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIA
MAV_3226|M.avium_104 QPVPYMAVYSATKAFVQTFSEAVHEELHGSGVSVTCLCPGPVPTEWAEIA
Mvan_3113|M.vanbaalenii_PYR-1 QPLPGAAVYSATKAYVQTFSEAVHEGLHGTGVSCTALCPGPVPTEWWEIA
MAB_4261c|M.abscessus_ATCC_199 VSG-RGSTYSASKAWVVSFTEGLANGLLGTGVGMHVLCPGFIHTEFHERA
MSMEG_4722|M.smegmatis_MC2_155 SPIPNNATYAASKAFANTFSESLRGELTGVGVHVTLLAPGPVRTELPDPS
TH_1383|M.thermoresistible__bu SPIPNNATYAATKAFANTFSESLRGELKDLGVHVTLLAPGPVRSDLPDPS
MLBr_00429|M.leprae_Br4923 SPIPYNATYAATKAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHD
. : *.*:**:. :::..: * . ** * ** : :. :
MMAR_0254|M.marinum_M GFTQQETES-LPKIMWKSVDQVAQAGIDGLAAGKAVVVPGLANRISAELI
MUL_4860|M.ulcerans_Agy99 GFTPQETES-LPKIMWKSVDQVAQAGIDGLAAGKAVVVPGLANRISAELI
Mflv_0138|M.gilvum_PYR-GCK GMDERTFASAFPKFLWIESREVAEKGIDGLAADRGSVIPGLQNEIPARVF
Mb1571|M.bovis_AF2122/97 S---AERFS-IPL-AQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSG
Rv1544|M.tuberculosis_H37Rv S---AERFS-IPL-AQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSG
MAV_3226|M.avium_104 N---AERFS-IPI-AQVSPRDVAEAAIGGMLTGRRTVVPGVVPKVVSTGG
Mvan_3113|M.vanbaalenii_PYR-1 ----GEKPP-GGK-VAVSVEEVAEAGIAAMREGKRLVVPGLVPKLTGLGG
MAB_4261c|M.abscessus_ATCC_199 G---IEMGT-IPEFMWLQVDDVVNACLHDIAAGKVLIVPGVQYKAITSVT
MSMEG_4722|M.smegmatis_MC2_155 E--QSLVERLIPDFLWIDTEYTAKLSLDGLEHNKMRVVPGVTSKAMSVAS
TH_1383|M.thermoresistible__bu E--ASLVDRLVPDFLWISTEHTAKLSLDGLAANKMRVVPGLTSKAMSVAS
MLBr_00429|M.leprae_Br4923 E--ASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKAMSVAS
. ... : : .: ::**: .
MMAR_0254|M.marinum_M RVTPPDWMGSIMARIHPAMKRQ--
MUL_4860|M.ulcerans_Agy99 RVTPPDWMGSIMARIHPAMKRQ--
Mflv_0138|M.gilvum_PYR-GCK EFLPRRILLPLIRNQHPALRRSRS
Mb1571|M.bovis_AF2122/97 RFAPRSLLLPAIRIGNRLRGGPSR
Rv1544|M.tuberculosis_H37Rv RFAPRSLLLPAIRIGNRLRGGPSR
MAV_3226|M.avium_104 RFAPRSLLLPGIRIGNRFRGGPKR
Mvan_3113|M.vanbaalenii_PYR-1 RFTPRALLLPALRMAAARRR----
MAB_4261c|M.abscessus_ATCC_199 RLIPRGLVRKYNSVVGRGRGRT--
MSMEG_4722|M.smegmatis_MC2_155 GYAPRAIVTPIVGAVYKKLGGG--
TH_1383|M.thermoresistible__bu GYAPRAIVAPIVGAFYKKLGGG--
MLBr_00429|M.leprae_Br4923 RYAPRAIVASIVGNFYKKLGGG--
* :