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SFVLATPELMTTAAQDLAAIRSTLGEASATAAAPTTALAAAAEDEISTGIAALFGAFGSDYQAISAQAQA FHEQLINLLTASGGAYLSAETAATATVTTGGFPSLVANTTANLQTIADTWTNQTVPILTHAVTGYPQLIS TSLASGNVLPLLAIPANLAQGSATLYQAFSSPVSLSLTSLTPSGISLGVGLGLPQLLALNALGAPVNAGL AAGASGTAIFGALQAGDTMGAISTLADTPANIANGFLNGSQTLSMQLSLPGLSVAADIPFSGLLSPLQPL SLTATTPVLPLLNSLTITGPPVGGLVPSLVQYVPELLATSLGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0111 | - | - | 100% (324) | PE family protein |
| M. marinum M | MMAR_2453 | - | 5e-35 | 32.54% (335) | PE family protein |
| M. marinum M | MMAR_2461 | - | 8e-35 | 35.73% (347) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1673 | PE17 | 2e-37 | 32.52% (329) | PE family protein |
| M. gilvum PYR-GCK | Mflv_1753 | - | 1e-08 | 26.34% (205) | hypothetical protein Mflv_1753 |
| M. tuberculosis H37Rv | Rv1646 | PE17 | 2e-37 | 32.52% (329) | PE family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-10 | 36.26% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_1346 | - | 5e-18 | 28.46% (267) | PE family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4350 | - | 2e-08 | 25.55% (227) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1632 | - | 3e-34 | 32.24% (335) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_4536 | - | 2e-06 | 27.47% (273) | hypothetical protein Mvan_4536 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1673|M.bovis_AF2122/97 ----MS-FLTVAPDMVTAAAGNLESVGS-ALNEAAAAAAPATVGLAAPAA
Rv1646|M.tuberculosis_H37Rv ----MS-FLTVAPDMVTAAAGNLESVGS-ALNEAAAAAAPATVGLAAPAA
MUL_1632|M.ulcerans_Agy99 ----MS-FLNVAPEMVAAAADNVESIGS-ALTAAQAAAAAPTIELVAPAA
MMAR_0111|M.marinum_M ----MS-FVLATPELMTTAAQDLAAIRS-TLGEASATAAAPTTALAAAAE
MLBr_01183|M.leprae_Br4923 ----MPLFLNAEPQALTAAANTLEGLSA-ATVASNAAAAQLTTEIAPPAA
MAV_1346|M.avium_104 ----MS-FVTTRPEALLAVASMLEGLGS-SMDAQNAAAAAPTTSIAPAAA
Mvan_4536|M.vanbaalenii_PYR-1 MHVTVRSYLTAGVALAGASAIALAPVVVPPSSTVSSSPAMSSVAVELSAA
Mflv_1753|M.gilvum_PYR-GCK MYTTLRPYATAGVAMLGASAIAIAPVVV---TPTLPDLKVVSTGVQLNAA
TH_4350|M.thermoresistible__bu MLASIRPYATAGVALVGAGVIAVTPVAP--PPADIQVSRQAVALSAISNP
: : . : . : :
Mb1673|M.bovis_AF2122/97 DRVSAVVAAMLGAYARDFQGISAQIAGFHNQFVGALRGGAAAYASAEAAN
Rv1646|M.tuberculosis_H37Rv DRVSAVVAAMLGAYARDFQGISAQIAGFHNQFVGALRGGAAAYASAEAAN
MUL_1632|M.ulcerans_Agy99 DGVSIAVTAAFWSAAEEFQELGAQAAAFHEQIVALLNTAAAAYAGAEAT-
MMAR_0111|M.marinum_M DEISTGIAALFGAFGSDYQAISAQAQAFHEQLINLLTASGGAYLSAETAA
MLBr_01183|M.leprae_Br4923 DDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN
MAV_1346|M.avium_104 DEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAAN
Mvan_4536|M.vanbaalenii_PYR-1 VNPITAWVDVFAGAATNLGGIGNAILEDPFPLLRQALENVLGYGGTLVSA
Mflv_1753|M.gilvum_PYR-GCK IDPLTPLLELFNSSEVNVAALVDAWLEAPAPILQQIIANQIGYLGQLPDI
TH_4350|M.thermoresistible__bu GDPVVAYGELIANTIGSLQGLGGQFAADPAPVLVKILQNQIANGQLIGSA
: .: .
Mb1673|M.bovis_AF2122/97 VQQTVVN----------------------------------AVNAPAQAL
Rv1646|M.tuberculosis_H37Rv VQQTVVN----------------------------------AVNAPAQAL
MUL_1632|M.ulcerans_Agy99 AKQALLG----------------------------------VVNGPAQAL
MMAR_0111|M.marinum_M TATVTTGGF-----------------------------PSLVANTTANLQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 RVNTSAA----------------------------------ALQGLAPNV
Mvan_4536|M.vanbaalenii_PYR-1 TTGAITGALNYFS---FDNPAGAWPLIEDAFTQLSEGNISGAITTAGEAL
Mflv_1753|M.gilvum_PYR-GCK GAILAQMGTNLVAGLRSPFAEDPSTLEPLHASIYELIVDGIPGAIEPAPP
TH_4350|M.thermoresistible__bu LDEALGFLLQG-----------VEALPGALEEAFALLTQGDLKGAVDAFM
Mb1673|M.bovis_AF2122/97 LGHPLIGPETVGSSAAAVSFG---FGPLLLAGS-DPLLAVPFSYPASLP-
Rv1646|M.tuberculosis_H37Rv LGHPLIGPETVGSSAAAVSFG---FGPLLLAGS-DPLLAVPFSYPASLP-
MUL_1632|M.ulcerans_Agy99 LGHSLVGPTAGGYTAAAADGT---SGGVVGALLGDPLLGVPFSAPYSFD-
MMAR_0111|M.marinum_M TIADTWTNQTVPILTHAVTGYPQLISTSLASGNVLPLLAIPANLAQGSA-
MLBr_01183|M.leprae_Br4923 --------------HDSL--------------------------------
MAV_1346|M.avium_104 IPNAAPAADPPPAGTTSLGTSIGWAQNVGAAASDFITLGEGQFAPVPGA-
Mvan_4536|M.vanbaalenii_PYR-1 LLGPILNIGLPIFTSGALEIPGKIAQNFANVVKSLTSLDTVFPIVLGALG
Mflv_1753|M.gilvum_PYR-GCK QLVPLLEFTTTYLSGVLVGLAGLVMNPVLALGGGIHSVFQSLIGEDADLG
TH_4350|M.thermoresistible__bu MGIIPAALGMIVPLVAGSMIITNTADNFARAVSAVLDVDAMLPTLLGFAG
Mb1673|M.bovis_AF2122/97 ---TPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYG----------
Rv1646|M.tuberculosis_H37Rv ---TPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYG----------
MUL_1632|M.ulcerans_Agy99 ---TPFGPVALTLNGTASPLG-EVVIDSGSLNVPLPLRLG----------
MMAR_0111|M.marinum_M ---TLYQAFSSPVSLSLTSLTPSGISLG--VGLGLPQLLA----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---AGIPNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMG----------
Mvan_4536|M.vanbaalenii_PYR-1 TVMAPMQALGGSLQAAFDALGEGNLIDAVVELINIPASVTGALLNGYTND
Mflv_1753|M.gilvum_PYR-GCK AAINTLINIPTAMADAFLNGGQSMVVTPLLTALGLELPIPGMEVELNFGG
TH_4350|M.thermoresistible__bu PVLSAVDGFVTSGQAVLDGVLAGDPIAVLNAVASTPAVLIDAVLNGSGAL
Mb1673|M.bovis_AF2122/97 LGAVGPALTTMT--------ALQNSG-----------TAFSGAVQSGNLL
Rv1646|M.tuberculosis_H37Rv LGAVGPALTTMT--------ALQNSG-----------TAFSGAVQSGNLL
MUL_1632|M.ulcerans_Agy99 VNALGPAITTAA--------ALQASG-----------TAFSGAVQSGDLL
MMAR_0111|M.marinum_M LNALGAPVNAGL--------AAGASG-----------TAIFGALQAGDTM
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 RGPSIGGLSVPP--------SWAPGG-----------VAPAANATPAQLV
Mvan_4536|M.vanbaalenii_PYR-1 MGTTYPGLFTFS--------ENPGEGGLIQALFVTLPKALAAAIAPEEAV
Mflv_1753|M.gilvum_PYR-GCK LLSPGGSMFNSLNLVFGPGDELPGQGAGLIGSLVALSKVIAKAIGWDGEG
TH_4350|M.thermoresistible__bu LGFLPLPGLLTPATAPIGGPIATLLGIRNAIADALQPVEQIAAASAAAPM
Mb1673|M.bovis_AF2122/97 GAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLGYESVGISVP-VGGLL
Rv1646|M.tuberculosis_H37Rv GAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLGYESVGISVP-VGGLL
MUL_1632|M.ulcerans_Agy99 GAAGALLTAPGSAVNGFLFGQTAISQMVPAPDGSGYTSVDVSVP-VGGLL
MMAR_0111|M.marinum_M GAISTLADTPANIANGFLNGSQTLSMQLSLPG----LSVAADIP-FSGLL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GAGFTSAAPDTAPVTAVPGG-------VPSMATAGRGGYGLGAP-RYGVK
Mvan_4536|M.vanbaalenii_PYR-1 ATAAAEGPADPDAGSGTMITVAEVAETDAAAETEAAAETEAAVV-ADGDT
Mflv_1753|M.gilvum_PYR-GCK NPLAPPLTPQSTLREATDTSLASVSTVTLETGTAAVVDAAEDAESASGGS
TH_4350|M.thermoresistible__bu AAKAEVKAEEEVDAVAAVTSVPGENFRTVNLTTELSTAVENPVAGEPKKS
Mb1673|M.bovis_AF2122/97 APLQPVTVTLT-PTSGMPTAIQLSGTQFGGLLPALLNGF-----------
Rv1646|M.tuberculosis_H37Rv APLQPVTVTLT-PTSGMPTAIQLSGTQFGGLLPALLNGF-----------
MUL_1632|M.ulcerans_Agy99 APTSVATLTLT-PASGAPTAILLDGSKFGGLITGLLDDFVPGF-------
MMAR_0111|M.marinum_M SPLQPLSLTATTPVLPLLNSLTITGPPVGGLVPSLVQYVPELLATSLGP-
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PTVMPKPAI-----------------------------------------
Mvan_4536|M.vanbaalenii_PYR-1 VVEEAPAVVVDEATAPVDGGEEATTPADDVVTAPVDDVVTAPVDEAGDDV
Mflv_1753|M.gilvum_PYR-GCK APESSTAPAVSEDQDGEGVAEEDDTAAYDEAVKDEVETVEEEVEEVAEEA
TH_4350|M.thermoresistible__bu AAVDGVPTTVATEEATTGATESLDPAAATEGDDGLEDDSAKNANGGTDLS
Mb1673|M.bovis_AF2122/97 --------------------------------------------------
Rv1646|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1632|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0111|M.marinum_M --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mvan_4536|M.vanbaalenii_PYR-1 EAAPDETDTADDTAGEDDGDSAGGAGGESGGAGGESGGDD----------
Mflv_1753|M.gilvum_PYR-GCK EEVEEAEVADTDVETETETETEKTEAEKTEKTEAEKTETESGTDAGAE--
TH_4350|M.thermoresistible__bu DGNKATPATTAGDTSADSGSNKAGQSTLRAGVKKATAKASAASSTGGSDE