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MSFLNVAPEMVAAAADNVESIGSALTAAQAAAAAPTIELVAPAADGVSIAVTAAFWSAAEEFQELGAQAA AFHEQIVALLNTAAAAYAGAEATAKQALLGVVNGPAQALLGHSLVGPTAGGYTAAAADGTSGGVVGALLG DPLLGVPFSAPYSFDTPFGPVALTLNGTASPLGEVVIDSGSLNVPLPLRLGVNALGPAITTAAALQASGT AFSGAVQSGDLLGAAGALLTAPGSAVNGFLFGQTAISQMVPAPDGSGYTSVDVSVPVGGLLAPTSVATLT LTPASGAPTAILLDGSKFGGLITGLLDDFVPGF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1632 | - | - | 100% (313) | PE family protein |
| M. ulcerans Agy99 | MUL_3318 | - | 4e-30 | 35.46% (282) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_1145 | - | 2e-29 | 51.39% (144) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1673 | PE17 | 4e-94 | 60.45% (311) | PE family protein |
| M. gilvum PYR-GCK | Mflv_0326 | - | 8e-06 | 30.21% (96) | PE domain-containing protein |
| M. tuberculosis H37Rv | Rv1646 | PE17 | 4e-94 | 60.45% (311) | PE family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-13 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_2231c | - | 1e-06 | 34.38% (96) | PE family protein |
| M. marinum M | MMAR_2453 | - | 1e-170 | 99.36% (313) | PE family protein |
| M. avium 104 | MAV_1346 | - | 8e-16 | 31.49% (289) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0618 | - | 7e-06 | 35.71% (98) | PE family protein |
| M. thermoresistible (build 8) | TH_3688 | - | 9e-05 | 35.16% (91) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_0414 | - | 1e-08 | 35.42% (96) | PE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1632|M.ulcerans_Agy99 --------MS-FLNVAPEMVAAAADNVESIGSALTAAQAAAAAPTIELVA
MMAR_2453|M.marinum_M --------MS-FLNVAPEMVAAAADNVESIGSALTAAQAAAAAPTIELVA
Mb1673|M.bovis_AF2122/97 --------MS-FLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAA
Rv1646|M.tuberculosis_H37Rv --------MS-FLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAA
MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAP
MAV_1346|M.avium_104 --------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAP
Mflv_0326|M.gilvum_PYR-GCK --------MT--LRVVPEGLTAASAAVEALTARMAAAHAAAAPLVTAVLP
Mvan_0414|M.vanbaalenii_PYR-1 --------MT--LRVVPEGLTAAGAAVEALTARMAAAHAAAAPVVTAVLP
MSMEG_0618|M.smegmatis_MC2_155 --------MT--LRVVPEGLTAASSAVEALTARLAAAHAAAAPMISTVLP
MAB_2231c|M.abscessus_ATCC_199 --------MN--LNVVPEGLTATSAAVEALTARLAAAHAAAAPVIGAVVP
TH_3688|M.thermoresistible__bu MLSSIRPYATAGVALVGAGVIAVAPTVTPPLPDIKVPATVASPVQLTVSP
: : *.. : . :.*: : .
MUL_1632|M.ulcerans_Agy99 PAADG---------VSIAVTAAFWSAAEEFQELGAQAAAFHEQIVALLNT
MMAR_2453|M.marinum_M PAADG---------VSIAVTAAFGSAAEEFQELGAQAAAFHEQIVALLNT
Mb1673|M.bovis_AF2122/97 PAADR---------VSAVVAAMLGAYARDFQGISAQIAGFHNQFVGALRG
Rv1646|M.tuberculosis_H37Rv PAADR---------VSAVVAAMLGAYARDFQGISAQIAGFHNQFVGALRG
MLBr_01183|M.leprae_Br4923 PAADD---------VSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLT
MAV_1346|M.avium_104 AAADE---------VSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDT
Mflv_0326|M.gilvum_PYR-GCK PAADA---------VSLQTATGLSANGVEHQSIAARGVEELGRSGVGVGD
Mvan_0414|M.vanbaalenii_PYR-1 PAADV---------VSLQAATGFSARAAEHQSVAAQGVEELGRSGIAVGE
MSMEG_0618|M.smegmatis_MC2_155 PAADA---------VSLQTAAGFSANGAQQSAVAAQGVEELGRSGVGVGE
MAB_2231c|M.abscessus_ATCC_199 PAADP---------VSLETAAGFSARGIEHSGVAAQAVEELGRAGLGVSE
TH_3688|M.thermoresistible__bu IEFYTGLFERTTGNASALVEKFLANPAPILSQIIENQVANLEFAMEVIPT
.* : . . . :
MUL_1632|M.ulcerans_Agy99 AA-------------------AAYAGAEAT-AKQALLGVVNGPAQALLGH
MMAR_2453|M.marinum_M AA-------------------AAYAGAEAT-AKQALLGVVNGPAQALLGH
Mb1673|M.bovis_AF2122/97 GA-------------------AAYASAEAANVQQTVVNAVNAPAQALLGH
Rv1646|M.tuberculosis_H37Rv GA-------------------AAYASAEAANVQQTVVNAVNAPAQALLGH
MLBr_01183|M.leprae_Br4923 SS-------------------SAYAGTETAN-------------------
MAV_1346|M.avium_104 NA-------------------DSYGATEAANRVNTSAAALQGLAPNVIPN
Mflv_0326|M.gilvum_PYR-GCK SA-------------------ASYVSGDAMAATSYLIARG----------
Mvan_0414|M.vanbaalenii_PYR-1 SA-------------------ASYAGGDAMAASSYLIARG----------
MSMEG_0618|M.smegmatis_MC2_155 SG-------------------VSYATGDAQAAASYLTARGL---------
MAB_2231c|M.abscessus_ATCC_199 SA-------------------ASYTTGDMQAAAAYMIARG----------
TH_3688|M.thermoresistible__bu SINDAIEVFNTVGRAQLEIAFQQLAEGDLYGAVQTVQNIMLPVALPLLEA
:
MUL_1632|M.ulcerans_Agy99 SLVGPTAGGYTAAAADGTSGGVVGALLGDPLLGVPFSAPYSFDTPFGPVA
MMAR_2453|M.marinum_M SLVGPTAGGYTAAAADGTSGGVVGALLGDPLLGVPFSAPYSFDTPFGPVA
Mb1673|M.bovis_AF2122/97 PLIGPETVGSSAAAVSFGFGPLLLAGS-DPLLAVPFSYPASLPTPFGPVT
Rv1646|M.tuberculosis_H37Rv PLIGPETVGSSAAAVSFGFGPLLLAGS-DPLLAVPFSYPASLPTPFGPVT
MLBr_01183|M.leprae_Br4923 -----------HDSL-----------------------------------
MAV_1346|M.avium_104 AAPAADPPPAGTTSLGTSIG------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3688|M.thermoresistible__bu LGAPLRPIMMASDNLNRVVQQVIPSLILAGPIALIGPINATMAAAVYVVQ
MUL_1632|M.ulcerans_Agy99 LTLNGTASPLG-EVVIDSGSLNVPLPLRLGVNALG----PAITTAAALQA
MMAR_2453|M.marinum_M LTLNGTASPLG-EVVIDSGSLNVPLPLRLGVNALG----PAITTAAALQA
Mb1673|M.bovis_AF2122/97 MTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVG----PALTTMTALQN
Rv1646|M.tuberculosis_H37Rv MTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVG----PALTTMTALQN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --WAQNVGAAASDFITLGEGQFAPVPGAAGIPNFN----PGLTAATTAGP
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3688|M.thermoresistible__bu SIADGVMSGDPIEVVNALINAPGVVIDGFLNGGYGGVLNGGILSVAGMGP
MUL_1632|M.ulcerans_Agy99 SGTAFSGAVQSGDLLGAAGALLTAPGSAVNGFLFGQTAISQMVPAPDGSG
MMAR_2453|M.marinum_M SGTAFSGAVQSGDLLGAAGALLTAPGSAVNGFLFGQTAISQMVPAPDGSG
Mb1673|M.bovis_AF2122/97 SGTAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLG
Rv1646|M.tuberculosis_H37Rv SGTAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PAPAAPAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGVAPAANATPAQLV
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3688|M.thermoresistible__bu PGPIDLLLTFREQIAQALVPQGPYAPTTSAASAVEESAPPTAQVTKTTLG
MUL_1632|M.ulcerans_Agy99 YTSVDVSVPVGGLLAPTSVATLTLTPASGAPTAILLDGSKFGGLITGLLD
MMAR_2453|M.marinum_M YTSVDVSVPVGGLLAPTSVATLTLTPTSGAPTAILLDGSKFGGLITGLLD
Mb1673|M.bovis_AF2122/97 YESVGISVPVGGLLAPLQPVTVTLTPTSGMPTAIQLSGTQFGGLLPALLN
Rv1646|M.tuberculosis_H37Rv YESVGISVPVGGLLAPLQPVTVTLTPTSGMPTAIQLSGTQFGGLLPALLN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GAGFTSAAPDTAPVTAVPGGVPSMATAG--RGGYGLGAPRYGVKPTVMPK
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3688|M.thermoresistible__bu NNVVDVEVSATSLDTTTSSAAGPEGNSTPVAKTGNDGAGSENPVEQVESE
MUL_1632|M.ulcerans_Agy99 DFVPGF--------------------------------------------
MMAR_2453|M.marinum_M DFVPGF--------------------------------------------
Mb1673|M.bovis_AF2122/97 GF------------------------------------------------
Rv1646|M.tuberculosis_H37Rv GF------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PAI-----------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3688|M.thermoresistible__bu GLSDTGLSDDDSTTALKNDESTTPSGGTDLSNGNKVSPTATTAATTQNGV
MUL_1632|M.ulcerans_Agy99 -----------------------------------------------
MMAR_2453|M.marinum_M -----------------------------------------------
Mb1673|M.bovis_AF2122/97 -----------------------------------------------
Rv1646|M.tuberculosis_H37Rv -----------------------------------------------
MLBr_01183|M.leprae_Br4923 -----------------------------------------------
MAV_1346|M.avium_104 -----------------------------------------------
Mflv_0326|M.gilvum_PYR-GCK -----------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 -----------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155 -----------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 -----------------------------------------------
TH_3688|M.thermoresistible__bu AKNRGLTKASLGDATGGSSGGDSGSATGSSRTTAGSGNTGGSDSGDE