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MSFLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAAPAADRVSAVVAAMLGAYARDFQGISAQIA GFHNQFVGALRGGAAAYASAEAANVQQTVVNAVNAPAQALLGHPLIGPETVGSSAAAVSFGFGPLLLAGS DPLLAVPFSYPASLPTPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVGPALTTMTALQNSG TAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAISQSIPGPSNLGYESVGISVPVGGLLAPLQPVTV TLTPTSGMPTAIQLSGTQFGGLLPALLNGF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1646 | PE17 | - | 100% (310) | PE FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | 3e-33 | 55.56% (117) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv3590c | PE_PGRS58 | 2e-32 | 36.99% (319) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1673 | PE17 | 1e-172 | 100.00% (310) | PE family protein |
| M. gilvum PYR-GCK | Mflv_0326 | - | 1e-05 | 33.71% (89) | PE domain-containing protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-11 | 38.04% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_2231c | - | 3e-05 | 38.46% (65) | PE family protein |
| M. marinum M | MMAR_2453 | - | 2e-95 | 61.09% (311) | PE family protein |
| M. avium 104 | MAV_1346 | - | 1e-17 | 27.37% (285) | PE family protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1632 | - | 4e-94 | 60.45% (311) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0414 | - | 3e-06 | 34.83% (89) | PE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1646|M.tuberculosis_H37Rv -MSFLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAAPAADRVSA
Mb1673|M.bovis_AF2122/97 -MSFLTVAPDMVTAAAGNLESVGSALNEAAAAAAPATVGLAAPAADRVSA
MMAR_2453|M.marinum_M -MSFLNVAPEMVAAAADNVESIGSALTAAQAAAAAPTIELVAPAADGVSI
MUL_1632|M.ulcerans_Agy99 -MSFLNVAPEMVAAAADNVESIGSALTAAQAAAAAPTIELVAPAADGVSI
Mflv_0326|M.gilvum_PYR-GCK --MTLRVVPEGLTAASAAVEALTARMAAAHAAAAPLVTAVLPPAADAVSL
Mvan_0414|M.vanbaalenii_PYR-1 --MTLRVVPEGLTAAGAAVEALTARMAAAHAAAAPVVTAVLPPAADVVSL
MAB_2231c|M.abscessus_ATCC_199 --MNLNVVPEGLTATSAAVEALTARLAAAHAAAAPVIGAVVPPAADPVSL
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_1346|M.avium_104 MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSA
: . *: : *.. :*.: : **** : ..*** **
Rv1646|M.tuberculosis_H37Rv VVAAMLGAYARDFQGISAQIAGFHNQFVGALRGGAAAYASAEAANVQQTV
Mb1673|M.bovis_AF2122/97 VVAAMLGAYARDFQGISAQIAGFHNQFVGALRGGAAAYASAEAANVQQTV
MMAR_2453|M.marinum_M AVTAAFGSAAEEFQELGAQAAAFHEQIVALLNTAAAAYAGAEAT-AKQAL
MUL_1632|M.ulcerans_Agy99 AVTAAFWSAAEEFQELGAQAAAFHEQIVALLNTAAAAYAGAEAT-AKQAL
Mflv_0326|M.gilvum_PYR-GCK QTATGLSANGVEHQSIAARGVEELGRSGVGVGDSAASYVSGDAMAATSYL
Mvan_0414|M.vanbaalenii_PYR-1 QAATGFSARAAEHQSVAAQGVEELGRSGIAVGESAASYAGGDAMAASSYL
MAB_2231c|M.abscessus_ATCC_199 ETAAGFSARGIEHSGVAAQAVEELGRAGLGVSESAASYTTGDMQAAAAYM
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN-----
MAV_1346|M.avium_104 LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTS
: : . . .. .:: : : :* :
Rv1646|M.tuberculosis_H37Rv VNAVNAPAQALLGHPLIGPETVGSSAAAVSFGFGPLLLAGS-DPLLAVPF
Mb1673|M.bovis_AF2122/97 VNAVNAPAQALLGHPLIGPETVGSSAAAVSFGFGPLLLAGS-DPLLAVPF
MMAR_2453|M.marinum_M LGVVNGPAQALLGHSLVGPTAGGYTAAAADGTSGGVVGALLGDPLLGVPF
MUL_1632|M.ulcerans_Agy99 LGVVNGPAQALLGHSLVGPTAGGYTAAAADGTSGGVVGALLGDPLLGVPF
Mflv_0326|M.gilvum_PYR-GCK IARG----------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 IARG----------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 IARG----------------------------------------------
MLBr_01183|M.leprae_Br4923 -------------------------HDSL---------------------
MAV_1346|M.avium_104 AAALQGLAPNVIPNAAPAADPPPAGTTSLGTSIG----------------
Rv1646|M.tuberculosis_H37Rv SYPASLPTPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVGP
Mb1673|M.bovis_AF2122/97 SYPASLPTPFGPVTMTLNGSFDPLTQQVVFDSGSLTAPAPFVYGLGAVGP
MMAR_2453|M.marinum_M SAPYSFDTPFGPVALTLNGTASPLG-EVVIDSGSLNVPLPLRLGVNALGP
MUL_1632|M.ulcerans_Agy99 SAPYSFDTPFGPVALTLNGTASPLG-EVVIDSGSLNVPLPLRLGVNALGP
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------WAQNVGAAASDFITLGEGQFAPVPGAAGIPNFNP
Rv1646|M.tuberculosis_H37Rv ALTTMTALQNSGTAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAIS
Mb1673|M.bovis_AF2122/97 ALTTMTALQNSGTAFSGAVQSGNLLGAAGALLQAPGNAVTGFLFGQTAIS
MMAR_2453|M.marinum_M AITTAAALQASGTAFSGAVQSGDLLGAAGALLTAPGSAVNGFLFGQTAIS
MUL_1632|M.ulcerans_Agy99 AITTAAALQASGTAFSGAVQSGDLLGAAGALLTAPGSAVNGFLFGQTAIS
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GLTAATTAGPPAPAAPAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGVAP
Rv1646|M.tuberculosis_H37Rv QSIPGPSNLGYESVGISVPVGGLLAPLQPVTVTLTPTSGMPTAIQLSGTQ
Mb1673|M.bovis_AF2122/97 QSIPGPSNLGYESVGISVPVGGLLAPLQPVTVTLTPTSGMPTAIQLSGTQ
MMAR_2453|M.marinum_M QMVPAPDGSGYTSVDVSVPVGGLLAPTSVATLTLTPTSGAPTAILLDGSK
MUL_1632|M.ulcerans_Agy99 QMVPAPDGSGYTSVDVSVPVGGLLAPTSVATLTLTPASGAPTAILLDGSK
Mflv_0326|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2231c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AANATPAQLVGAGFTSAAPDTAPVTAVPGGVPSMATAGRGGYGLGAPRYG
Rv1646|M.tuberculosis_H37Rv FGGLLPALLNGF----
Mb1673|M.bovis_AF2122/97 FGGLLPALLNGF----
MMAR_2453|M.marinum_M FGGLITGLLDDFVPGF
MUL_1632|M.ulcerans_Agy99 FGGLITGLLDDFVPGF
Mflv_0326|M.gilvum_PYR-GCK ----------------
Mvan_0414|M.vanbaalenii_PYR-1 ----------------
MAB_2231c|M.abscessus_ATCC_199 ----------------
MLBr_01183|M.leprae_Br4923 ----------------
MAV_1346|M.avium_104 VKPTVMPKPAI-----