For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
IHIARTWRGFAGCMAAGFVGVTLIASGTASADPLYPQPPSPAPAPAQAAVPPVQNLNASPGSITNRFAPV PAQVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITPAVTGTVRDYLNGKGVKLE AQRPQGFNALEITLPMPPRWTPVPDPNVPDAFAVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGF VDSQNLLAWRTTNASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVTTAQSQAVAD APATDAIINGFRVAAPTAAGHTPARAGAPAAVAPQTPARAASPAAPAQAPVSIPHHPAAATAPAQAPVPN LTPALQAVPGQVAAAPPVAAAPAPSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0056 | mtc28 | - | 100% (377) | secreted proline rich protein Mtc28 |
| M. marinum M | MMAR_4470 | lpqT | 4e-20 | 31.89% (185) | lipoprotein LpqT |
| M. marinum M | MMAR_4294 | - | 7e-11 | 39.06% (128) | hypothetical protein MMAR_4294 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0041c | mtc28 | 1e-115 | 61.02% (354) | secreted proline rich protein MTC28 (proline rich 28 kDa |
| M. gilvum PYR-GCK | Mflv_0852 | - | 1e-82 | 54.05% (333) | hypothetical protein Mflv_0852 |
| M. tuberculosis H37Rv | Rv0040c | mtc28 | 1e-115 | 61.02% (354) | secreted proline rich protein MTC28 (proline rich 28 kDa |
| M. leprae Br4923 | MLBr_00031 | - | 4e-90 | 57.88% (311) | hypothetical protein MLBr_00031 |
| M. abscessus ATCC 19977 | MAB_4924 | - | 1e-58 | 42.91% (289) | hypothetical protein MAB_4924 |
| M. avium 104 | MAV_0054 | - | 1e-102 | 55.70% (377) | proline-rich 28 kDa antigen |
| M. smegmatis MC2 155 | MSMEG_6919 | - | 8e-79 | 51.21% (330) | proline-rich 28 kDa antigen |
| M. thermoresistible (build 8) | TH_0510 | - | 7e-84 | 56.33% (316) | SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA |
| M. ulcerans Agy99 | MUL_0055 | mtc28 | 0.0 | 98.67% (377) | secreted proline rich protein Mtc28 |
| M. vanbaalenii PYR-1 | Mvan_6055 | - | 1e-82 | 50.84% (356) | hypothetical protein Mvan_6055 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0056|M.marinum_M ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
MUL_0055|M.ulcerans_Agy99 ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
Mb0041c|M.bovis_AF2122/97 ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
Rv0040c|M.tuberculosis_H37Rv ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
MLBr_00031|M.leprae_Br4923 ------------------MIQSTQTWRVLAG---GLAATAMGVTVFAGGT
MAV_0054|M.avium_104 ------------------MIEIVPGHRAVLG---GMVAGLIGLAVAAGGT
MSMEG_6919|M.smegmatis_MC2_155 ------------------MTESARRWRVLS---AGVAAGLAGFVSLAGNT
TH_0510|M.thermoresistible__bu -----------------------------------VAAGLTGILGFAGST
Mflv_0852|M.gilvum_PYR-GCK MDTFVAYRLTTWERTAPKMSESARHWRILAGGIGALAG-IAGVLGVTS-T
Mvan_6055|M.vanbaalenii_PYR-1 ------------------MSEIARHWRVLAGGIGACAAGVAGVLGVAAST
MAB_4924|M.abscessus_ATCC_1997 ------------------MTTTRYSVRFAAA-----TASVAALLAGTAAV
. .. :.
MMAR_0056|M.marinum_M ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPVPA
MUL_0055|M.ulcerans_Agy99 ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPAPA
Mb0041c|M.bovis_AF2122/97 ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
Rv0040c|M.tuberculosis_H37Rv ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
MLBr_00031|M.leprae_Br4923 AAADPSPPAP---PPAIPGVLPPASLPPIQSVTAVPGGITTNNRFVATPQ
MAV_0054|M.avium_104 ASADPLPPAPAPVPAPAPANLGPELVPPSRYLAAPQATTAATQITPATPG
MSMEG_6919|M.smegmatis_MC2_155 ASAEPVLPMPPAPVPSPVVQQAAPLAPAAAPAAAAVPGTSSLGVTNQTPG
TH_0510|M.thermoresistible__bu ASAQPLVPQPPPPPAPATVTQTVTVAAAPVAPVAPVTPVGPVNRTPPVAV
Mflv_0852|M.gilvum_PYR-GCK ASAQPAVPQPTVP-QPVIPQASIPQVSVPAPAAV-------------ASA
Mvan_6055|M.vanbaalenii_PYR-1 ASAQPMIPQPALP-APATVTQTVIVTPDTAPAALGQPGVTPA--TTGAAA
MAB_4924|M.abscessus_ATCC_1997 AMADPQ-PAPVPPVPAATANAAVAPAPNAAPAPAVAPTTS----------
* *:* * * . .
MMAR_0056|M.marinum_M QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
MUL_0055|M.ulcerans_Agy99 QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
Mb0041c|M.bovis_AF2122/97 --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
Rv0040c|M.tuberculosis_H37Rv --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
MLBr_00031|M.leprae_Br4923 -------------APGPAALG---------------------QPPLAVAA
MAV_0054|M.avium_104 -------TPGPAPAPAPAQAP---------------------APAPAPAP
MSMEG_6919|M.smegmatis_MC2_155 VPAATVPTGTVP-TGAVPAAP-------------------AAVPQPAIVP
TH_0510|M.thermoresistible__bu DPATGVAIGTAPAAGTTPALP-------------------VAVPRETIVP
Mflv_0852|M.gilvum_PYR-GCK VPAA--ANALPAAAPVAPAVP-------------------PAPRPPTIVP
Mvan_6055|M.vanbaalenii_PYR-1 VPAG--VSAG-VGAPAAPALP-------------------TRP-VSTIAP
MAB_4924|M.abscessus_ATCC_1997 ---------ANPLQPAAP--------------------------IAGVAP
. ..
MMAR_0056|M.marinum_M AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
MUL_0055|M.ulcerans_Agy99 AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
Mb0041c|M.bovis_AF2122/97 AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
Rv0040c|M.tuberculosis_H37Rv AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
MLBr_00031|M.leprae_Br4923 PVSESLHDYFKAKNIKLVAQKPHGFKALDITLPVPTRWTQVPDPNVPDAF
MAV_0054|M.avium_104 ATSGTIREFLQSKGVKFEAQKPQGFKALDITLPMPARWTQVPDPNVPDAF
MSMEG_6919|M.smegmatis_MC2_155 ATSGTLSEFLAEHGVKMEPQVADNFTALNIVLPMPTNWTKVPDPNVPNAF
TH_0510|M.thermoresistible__bu ARSGTLRDFFTERGVKMEPQAADGFTALNIVLPMPRGWAHVPDPNVPDAF
Mflv_0852|M.gilvum_PYR-GCK ATSGTLAEFFAAKGVTLEPQNSRDFRALNIVLPMPRGWELIPDPNVPNAF
Mvan_6055|M.vanbaalenii_PYR-1 ATSGTLAEFFAAKGVAMEPQSSRDFRALNIVLPKPRGWEHIPDPNVPDAF
MAB_4924|M.abscessus_ATCC_1997 AADGTLSEFFASKNVKVEPLTKSSHGVPRISIPIPNNWANVPDPNVPNAY
. :: :.: :.: . . .. . * :* * * :******:*:
MMAR_0056|M.marinum_M AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
MUL_0055|M.ulcerans_Agy99 AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
Mb0041c|M.bovis_AF2122/97 VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
Rv0040c|M.tuberculosis_H37Rv VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
MLBr_00031|M.leprae_Br4923 AVIADRLG-NSLYTSNAQLVVYNLVGNFDPKEAITHGFVDTQQLSAWQTT
MAV_0054|M.avium_104 AVIADRHG-SSIYSSNAQVVVYKLVGNFDPREAITHGYVDSQKLPAWQPT
MSMEG_6919|M.smegmatis_MC2_155 AVIADRTSK-DLYTPNAQVVVYKLIGDFDPRAAISHGYVDSQKLLGWRTT
TH_0510|M.thermoresistible__bu AVIADRVGG-GFYTSNAQVVVYKLIGDFDPKEAISHGYIDSLQLPAWRTT
Mflv_0852|M.gilvum_PYR-GCK AVLADRVGGNGLYSSNAQVIVYKLIGQFDPREAISHGFVESQKLPAWRTT
Mvan_6055|M.vanbaalenii_PYR-1 AVLADRVGGNGLYSSNAQVVVYKLVGAFDPKEAISHGFIDSQKLPAWRST
MAB_4924|M.abscessus_ATCC_1997 QVIVSKANGTGIYQSNAQLTMSKLIGEFDTNEAVSHGPVEVKALQGWQPT
*:..: . ..* .***: : .*:* :*. *::** :: * .*:.*
MMAR_0056|M.marinum_M NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
MUL_0055|M.ulcerans_Agy99 NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
Mb0041c|M.bovis_AF2122/97 NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
Rv0040c|M.tuberculosis_H37Rv NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
MLBr_00031|M.leprae_Br4923 NASKADFDGFPSSIIEGTYRENGMTLNTSRRHVIASSGPDKYLVSLSVT-
MAV_0054|M.avium_104 NASMADFGGFPSSIVEGTYRDGDLTLNTSRRHVIATSGPDKYLVSLAVT-
MSMEG_6919|M.smegmatis_MC2_155 DMAMGDFYGFPSSFIEGSYTEGSQVLNTSRRHVIATSGDDRYLVSLSVNW
TH_0510|M.thermoresistible__bu AQSMADHHGWPSSLIEGTYRDNSVTLNTSRRHVIATSGSDRYLVSLSVT-
Mflv_0852|M.gilvum_PYR-GCK DASLAEFGGMPSSVIEGTYRENNMTLNTSRRNVIATVGPDNYLVSLAVT-
Mvan_6055|M.vanbaalenii_PYR-1 DASLADFGGMPSSLIEGTYRENNLTLNTSRRHVIATVGPDSYLVSLSVT-
MAB_4924|M.abscessus_ATCC_1997 DASLVTYQGFPSSIVEGTFRQDGETLNTSRRAVIITQGKDRFLVQLAVT-
: . * ***.:**:: :.. .****** ** : * : :**.*:*.
MMAR_0056|M.marinum_M TAQSQAV-ADAPATDAIINGFR------VAAPTAAGHTPARAGAPAAVAP
MUL_0055|M.ulcerans_Agy99 TAQSQAV-ADAPATDAIINGFR------VATPTAAGHTPARAGAATAVAP
Mb0041c|M.bovis_AF2122/97 TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
Rv0040c|M.tuberculosis_H37Rv TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
MLBr_00031|M.leprae_Br4923 TALSQAV-ADAPATNAIVNGFR------VSSPTVSAPVPP----------
MAV_0054|M.avium_104 TDRAVAV-ADAPATDAIVNGFR------VTVPGASAPAPTAAP------V
MSMEG_6919|M.smegmatis_MC2_155 SAANQGISAAADATDAIVSGFR------VSAPAPA---------------
TH_0510|M.thermoresistible__bu TEVDQAV-AAAEATDAIVNGFK------VTSPTRP---------------
Mflv_0852|M.gilvum_PYR-GCK TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVMPLPGA-------
Mvan_6055|M.vanbaalenii_PYR-1 TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVAPLPGT-------
MAB_4924|M.abscessus_ATCC_1997 TTVGNAI-AEAPATDLIVNGLRFGDAAPVTAPVADPNALADPDAVPG---
: : : . **: *:.*:: *
MMAR_0056|M.marinum_M QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPVPNLTPALQAVPGQVAA
MUL_0055|M.ulcerans_Agy99 QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPAPNLTPALQAVPGQVAA
Mb0041c|M.bovis_AF2122/97 ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
Rv0040c|M.tuberculosis_H37Rv ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
MLBr_00031|M.leprae_Br4923 ----------QLGTR-----------------------------------
MAV_0054|M.avium_104 ALPAQAPAVAPVAPAPAPVAPAAPTAPAPAAAPLVPLAQTAPAAPAGLPA
MSMEG_6919|M.smegmatis_MC2_155 ----------PAAPPAAPAP-VAPPALPALPQ-LPGLPG-----------
TH_0510|M.thermoresistible__bu ----------SAPPAPVRAPSAAPVSLPASGAGLPAAQP-----------
Mflv_0852|M.gilvum_PYR-GCK ----------PALPLPAAAPQAPGAPAVAPPPQLLGLQG-----------
Mvan_6055|M.vanbaalenii_PYR-1 ----------PALPLASAPPPAPAVPTVAPAPQLLGLQG-----------
MAB_4924|M.abscessus_ATCC_1997 ------APATPAAGAPAAADPNAPASPAPGVPGLPPLPTLPALVPPAPPA
MMAR_0056|M.marinum_M APPVAAAPAPSR------------------
MUL_0055|M.ulcerans_Agy99 APPVAAAPAPSR------------------
Mb0041c|M.bovis_AF2122/97 -------PVPPR------------------
Rv0040c|M.tuberculosis_H37Rv -------PVPPR------------------
MLBr_00031|M.leprae_Br4923 ------------------------------
MAV_0054|M.avium_104 QPLPNQQHTPSLLAMVPGLPPLPNFSFLQH
MSMEG_6919|M.smegmatis_MC2_155 ------------------------------
TH_0510|M.thermoresistible__bu ------------------------------
Mflv_0852|M.gilvum_PYR-GCK ------------------------------
Mvan_6055|M.vanbaalenii_PYR-1 ------------------------------
MAB_4924|M.abscessus_ATCC_1997 A-----------------------------