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IQIARTWRVFAGGMATGFIGVVLVTAGKASADPLLPPPPIPAPVSAPATVPPVQNLTALPGGSSNRFSPA PAPAPIASPIPVGAPGSTAVPPLPPPVTPAISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQV PDPNVPDAFVVIADRLGNSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTTNASMANFDGFPS SIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVTTALSQAVTDGPATDAIVNGFQVVAHAAPAQAPA PAPGSAPVGLPGQAPGYPPAGTLTPVPPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0040c | mtc28 | - | 100% (310) | SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA ANTIGEN) |
| M. tuberculosis H37Rv | Rv1016c | lpqT | 8e-22 | 32.46% (228) | lipoprotein LpqT |
| M. tuberculosis H37Rv | Rv2082 | - | 3e-07 | 35.35% (99) | hypothetical protein Rv2082 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0041c | mtc28 | 0.0 | 100.00% (310) | secreted proline rich protein MTC28 (proline rich 28 kDa |
| M. gilvum PYR-GCK | Mflv_0852 | - | 3e-81 | 51.09% (321) | hypothetical protein Mflv_0852 |
| M. leprae Br4923 | MLBr_00031 | - | 5e-98 | 63.60% (283) | hypothetical protein MLBr_00031 |
| M. abscessus ATCC 19977 | MAB_4924 | - | 3e-55 | 42.38% (302) | hypothetical protein MAB_4924 |
| M. marinum M | MMAR_0056 | mtc28 | 1e-115 | 61.02% (354) | secreted proline rich protein Mtc28 |
| M. avium 104 | MAV_0054 | - | 3e-98 | 59.44% (323) | proline-rich 28 kDa antigen |
| M. smegmatis MC2 155 | MSMEG_6919 | - | 2e-77 | 51.91% (314) | proline-rich 28 kDa antigen |
| M. thermoresistible (build 8) | TH_0510 | - | 2e-82 | 55.78% (303) | SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA |
| M. ulcerans Agy99 | MUL_0055 | mtc28 | 1e-115 | 61.30% (354) | secreted proline rich protein Mtc28 |
| M. vanbaalenii PYR-1 | Mvan_6055 | - | 6e-81 | 52.20% (318) | hypothetical protein Mvan_6055 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0040c|M.tuberculosis_H37Rv ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
Mb0041c|M.bovis_AF2122/97 ------------------MIQIARTWRVFAG---GMATGFIGVVLVTAGK
MMAR_0056|M.marinum_M ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
MUL_0055|M.ulcerans_Agy99 ------------------MIHIARTWRGFAG---CMAAGFVGVTLIASGT
MLBr_00031|M.leprae_Br4923 ------------------MIQSTQTWRVLAG---GLAATAMGVTVFAGGT
MAV_0054|M.avium_104 ------------------MIEIVPGHRAVLG---GMVAGLIGLAVAAGGT
MSMEG_6919|M.smegmatis_MC2_155 ------------------MTESARRWRVLS---AGVAAGLAGFVSLAGNT
TH_0510|M.thermoresistible__bu -----------------------------------VAAGLTGILGFAGST
Mflv_0852|M.gilvum_PYR-GCK MDTFVAYRLTTWERTAPKMSESARHWRILAGGIGALAG-IAGVLGVTS-T
Mvan_6055|M.vanbaalenii_PYR-1 ------------------MSEIARHWRVLAGGIGACAAGVAGVLGVAAST
MAB_4924|M.abscessus_ATCC_1997 ------------------MTTTRYSVRFAAA-----TASVAALLAGTAAV
. .. :.
Rv0040c|M.tuberculosis_H37Rv ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
Mb0041c|M.bovis_AF2122/97 ASADPLLPPP---PIPAP-VSAPATVPPVQNLTALPGGSS--NRFSPAPA
MMAR_0056|M.marinum_M ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPVPA
MUL_0055|M.ulcerans_Agy99 ASADPLYPQP---PSPAP-APAQAAVPPVQNLNASPGSIT--NRFAPAPA
MLBr_00031|M.leprae_Br4923 AAADPSPPAP---PPAIPGVLPPASLPPIQSVTAVPGGITTNNRFVATPQ
MAV_0054|M.avium_104 ASADPLPPAPAPVPAPAPANLGPELVPPSRYLAAPQATTAATQITPATPG
MSMEG_6919|M.smegmatis_MC2_155 ASAEPVLPMPPAPVPSPVVQQAAPLAPAAAPAAAAVPGTSSLGVTNQTPG
TH_0510|M.thermoresistible__bu ASAQPLVPQPPPPPAPATVTQTVTVAAAPVAPVAPVTPVGPVNRTPPVAV
Mflv_0852|M.gilvum_PYR-GCK ASAQPAVPQPTVP-QPVIPQASIPQVSVPAPAAV-------------ASA
Mvan_6055|M.vanbaalenii_PYR-1 ASAQPMIPQPALP-APATVTQTVIVTPDTAPAALGQPGVTPA--TTGAAA
MAB_4924|M.abscessus_ATCC_1997 AMADPQ-PAPVPPVPAATANAAVAPAPNAAPAPAVAPTTS----------
* *:* * * . .
Rv0040c|M.tuberculosis_H37Rv --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
Mb0041c|M.bovis_AF2122/97 --PAPIASPIPVGAPGSTAVP---------------------PLPPPVTP
MMAR_0056|M.marinum_M QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
MUL_0055|M.ulcerans_Agy99 QVPAPMQVPAATAAPVPAAIPATGQMPAAGQVPAAGQLPVAAPVAPAITP
MLBr_00031|M.leprae_Br4923 -------------APGPAALG---------------------QPPLAVAA
MAV_0054|M.avium_104 -------TPGPAPAPAPAQAP---------------------APAPAPAP
MSMEG_6919|M.smegmatis_MC2_155 VPAATVPTGTVP-TGAVPAAP-------------------AAVPQPAIVP
TH_0510|M.thermoresistible__bu DPATGVAIGTAPAAGTTPALP-------------------VAVPRETIVP
Mflv_0852|M.gilvum_PYR-GCK VPAA--ANALPAAAPVAPAVP-------------------PAPRPPTIVP
Mvan_6055|M.vanbaalenii_PYR-1 VPAG--VSAG-VGAPAAPALP-------------------TRP-VSTIAP
MAB_4924|M.abscessus_ATCC_1997 ---------ANPLQPAAP--------------------------IAGVAP
. ..
Rv0040c|M.tuberculosis_H37Rv AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
Mb0041c|M.bovis_AF2122/97 AISGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAF
MMAR_0056|M.marinum_M AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
MUL_0055|M.ulcerans_Agy99 AVTGTVRDYLNGKGVKLEAQRPQGFNALEITLPMPPRWTPVPDPNVPDAF
MLBr_00031|M.leprae_Br4923 PVSESLHDYFKAKNIKLVAQKPHGFKALDITLPVPTRWTQVPDPNVPDAF
MAV_0054|M.avium_104 ATSGTIREFLQSKGVKFEAQKPQGFKALDITLPMPARWTQVPDPNVPDAF
MSMEG_6919|M.smegmatis_MC2_155 ATSGTLSEFLAEHGVKMEPQVADNFTALNIVLPMPTNWTKVPDPNVPNAF
TH_0510|M.thermoresistible__bu ARSGTLRDFFTERGVKMEPQAADGFTALNIVLPMPRGWAHVPDPNVPDAF
Mflv_0852|M.gilvum_PYR-GCK ATSGTLAEFFAAKGVTLEPQNSRDFRALNIVLPMPRGWELIPDPNVPNAF
Mvan_6055|M.vanbaalenii_PYR-1 ATSGTLAEFFAAKGVAMEPQSSRDFRALNIVLPKPRGWEHIPDPNVPDAF
MAB_4924|M.abscessus_ATCC_1997 AADGTLSEFFASKNVKVEPLTKSSHGVPRISIPIPNNWANVPDPNVPNAY
. :: :.: :.: . . .. . * :* * * :******:*:
Rv0040c|M.tuberculosis_H37Rv VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
Mb0041c|M.bovis_AF2122/97 VVIADRLG-NSVYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTT
MMAR_0056|M.marinum_M AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
MUL_0055|M.ulcerans_Agy99 AVIADRVGGNSVYTSNAQVVVYKLVGDLDPAEAISHGFVDSQNLLAWRTT
MLBr_00031|M.leprae_Br4923 AVIADRLG-NSLYTSNAQLVVYNLVGNFDPKEAITHGFVDTQQLSAWQTT
MAV_0054|M.avium_104 AVIADRHG-SSIYSSNAQVVVYKLVGNFDPREAITHGYVDSQKLPAWQPT
MSMEG_6919|M.smegmatis_MC2_155 AVIADRTSK-DLYTPNAQVVVYKLIGDFDPRAAISHGYVDSQKLLGWRTT
TH_0510|M.thermoresistible__bu AVIADRVGG-GFYTSNAQVVVYKLIGDFDPKEAISHGYIDSLQLPAWRTT
Mflv_0852|M.gilvum_PYR-GCK AVLADRVGGNGLYSSNAQVIVYKLIGQFDPREAISHGFVESQKLPAWRTT
Mvan_6055|M.vanbaalenii_PYR-1 AVLADRVGGNGLYSSNAQVVVYKLVGAFDPKEAISHGFIDSQKLPAWRST
MAB_4924|M.abscessus_ATCC_1997 QVIVSKANGTGIYQSNAQLTMSKLIGEFDTNEAVSHGPVEVKALQGWQPT
*:..: . ..* .***: : .*:* :*. *::** :: * .*:.*
Rv0040c|M.tuberculosis_H37Rv NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
Mb0041c|M.bovis_AF2122/97 NASMANFDGFPSSIIEGTYRENDMTLNTSRRHVIATSGADKYLVSLSVT-
MMAR_0056|M.marinum_M NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
MUL_0055|M.ulcerans_Agy99 NASMAEFGGFPSSVIEGTYRENDMTLNTSRRHVIAASGSENYLVSLSVT-
MLBr_00031|M.leprae_Br4923 NASKADFDGFPSSIIEGTYRENGMTLNTSRRHVIASSGPDKYLVSLSVT-
MAV_0054|M.avium_104 NASMADFGGFPSSIVEGTYRDGDLTLNTSRRHVIATSGPDKYLVSLAVT-
MSMEG_6919|M.smegmatis_MC2_155 DMAMGDFYGFPSSFIEGSYTEGSQVLNTSRRHVIATSGDDRYLVSLSVNW
TH_0510|M.thermoresistible__bu AQSMADHHGWPSSLIEGTYRDNSVTLNTSRRHVIATSGSDRYLVSLSVT-
Mflv_0852|M.gilvum_PYR-GCK DASLAEFGGMPSSVIEGTYRENNMTLNTSRRNVIATVGPDNYLVSLAVT-
Mvan_6055|M.vanbaalenii_PYR-1 DASLADFGGMPSSLIEGTYRENNLTLNTSRRHVIATVGPDSYLVSLSVT-
MAB_4924|M.abscessus_ATCC_1997 DASLVTYQGFPSSIVEGTFRQDGETLNTSRRAVIITQGKDRFLVQLAVT-
: . * ***.:**:: :.. .****** ** : * : :**.*:*.
Rv0040c|M.tuberculosis_H37Rv TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
Mb0041c|M.bovis_AF2122/97 TALSQAV-TDGPATDAIVNGFQ------VVAHAAPAQAPA----------
MMAR_0056|M.marinum_M TAQSQAV-ADAPATDAIINGFR------VAAPTAAGHTPARAGAPAAVAP
MUL_0055|M.ulcerans_Agy99 TAQSQAV-ADAPATDAIINGFR------VATPTAAGHTPARAGAATAVAP
MLBr_00031|M.leprae_Br4923 TALSQAV-ADAPATNAIVNGFR------VSSPTVSAPVPP----------
MAV_0054|M.avium_104 TDRAVAV-ADAPATDAIVNGFR------VTVPGASAPAPTAAP------V
MSMEG_6919|M.smegmatis_MC2_155 SAANQGISAAADATDAIVSGFR------VSAPAPA---------------
TH_0510|M.thermoresistible__bu TEVDQAV-AAAEATDAIVNGFK------VTSPTRP---------------
Mflv_0852|M.gilvum_PYR-GCK TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVMPLPGA-------
Mvan_6055|M.vanbaalenii_PYR-1 TSVDQVV-AAADATEAIVNGFK------VSVPGPAPVAPLPGT-------
MAB_4924|M.abscessus_ATCC_1997 TTVGNAI-AEAPATDLIVNGLRFGDAAPVTAPVADPNALADPDAVPG---
: : : . **: *:.*:: *
Rv0040c|M.tuberculosis_H37Rv ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
Mb0041c|M.bovis_AF2122/97 ---------PAPGSAPVGLP-----GQAPGYPPAGTLT------------
MMAR_0056|M.marinum_M QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPVPNLTPALQAVPGQVAA
MUL_0055|M.ulcerans_Agy99 QTPARAASPAAPAQAPVSIPHHPAAATAPAQAPAPNLTPALQAVPGQVAA
MLBr_00031|M.leprae_Br4923 ----------QLGTR-----------------------------------
MAV_0054|M.avium_104 ALPAQAPAVAPVAPAPAPVAPAAPTAPAPAAAPLVPLAQTAPAAPAGLPA
MSMEG_6919|M.smegmatis_MC2_155 ----------PAAPPAAPAP-VAPPALPALPQ-LPGLPG-----------
TH_0510|M.thermoresistible__bu ----------SAPPAPVRAPSAAPVSLPASGAGLPAAQP-----------
Mflv_0852|M.gilvum_PYR-GCK ----------PALPLPAAAPQAPGAPAVAPPPQLLGLQG-----------
Mvan_6055|M.vanbaalenii_PYR-1 ----------PALPLASAPPPAPAVPTVAPAPQLLGLQG-----------
MAB_4924|M.abscessus_ATCC_1997 ------APATPAAGAPAAADPNAPASPAPGVPGLPPLPTLPALVPPAPPA
Rv0040c|M.tuberculosis_H37Rv -------PVPPR------------------
Mb0041c|M.bovis_AF2122/97 -------PVPPR------------------
MMAR_0056|M.marinum_M APPVAAAPAPSR------------------
MUL_0055|M.ulcerans_Agy99 APPVAAAPAPSR------------------
MLBr_00031|M.leprae_Br4923 ------------------------------
MAV_0054|M.avium_104 QPLPNQQHTPSLLAMVPGLPPLPNFSFLQH
MSMEG_6919|M.smegmatis_MC2_155 ------------------------------
TH_0510|M.thermoresistible__bu ------------------------------
Mflv_0852|M.gilvum_PYR-GCK ------------------------------
Mvan_6055|M.vanbaalenii_PYR-1 ------------------------------
MAB_4924|M.abscessus_ATCC_1997 A-----------------------------