For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. leprae Br4923 MLBr_02649 (-)

annotation: hypothetical protein MLBr_02649
coordinates: 3169193 - 3170008
length: 271

SALNRRSFLGALAVSTVTGLGAVRLVVGPQPRTFVQAPVVAELTPTPNAAGVLPPPPTSARIPLPGGGVL
SKIPGRGDLLALTVDDGVNTEVVRSYVQFVKDTDIRLTFFVNGVYDSWTDNMSMLRPLVESGQIQLGNHT
WSHPDLTAMTKSEIATQLNRNDDFLKKNYGIAAQPYWRPPYAKHNATVDAVAVDLGYTVPTLWSGSLSDS
TLITEDYIVKMADQYFTPQAIVIGHLNHLPVTHVYPQLIDIIRSRHLRTVTLNDVFLTTS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02649--100% (271)hypothetical protein MLBr_02649
M. leprae Br4923MLBr_01950-2e-1327.81% (187) carbohydrate degrading enzyme

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1126-3e-1025.52% (192) glycosyl hydrolase
M. gilvum PYR-GCKMflv_2063-5e-0630.25% (119) polysaccharide deacetylase
M. tuberculosis H37RvRv1096-3e-1025.52% (192) glycosyl hydrolase
M. abscessus ATCC 19977MAB_2590-3e-7361.72% (209) putative polysaccharide deacetylase
M. marinum MMMAR_4371-8e-1428.12% (192) glycosyl hydrolase
M. avium 104MAV_5248-1e-12377.61% (268) polysaccharide deacetylase domain-containing protein
M. smegmatis MC2 155MSMEG_5023-8e-0922.28% (202) chitooligosaccharide deacetylase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0184-4e-1428.12% (192) glycosyl hydrolase
M. vanbaalenii PYR-1Mvan_4651-2e-1226.67% (210) polysaccharide deacetylase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4371|M.marinum_M               --MRKRPDNQAWRYWRMVVGVVAAVAVLV---------------------
MUL_0184|M.ulcerans_Agy99           --MRKRPDDQAWRYWRMVVGVVAAVAVLV---------------------
Mb1126|M.bovis_AF2122/97            --MPKRPDNQTWRYWRTVTGVVVAGAVLV---------------------
Rv1096|M.tuberculosis_H37Rv         --MPKRPDNQTWRYWRTVTGVVVAGAVLV---------------------
Mflv_2063|M.gilvum_PYR-GCK          --MTSESGALDDAHRRQARPIRRLGAVVLG--------------------
Mvan_4651|M.vanbaalenii_PYR-1       --MTSGSGAQYDTRGARARRIR-SAAILLG--------------------
MSMEG_5023|M.smegmatis_MC2_155      ---MRRRVLTVCLALVLCVVVVLAGGYWLS--------------------
MLBr_02649|M.leprae_Br4923          MSALNRRSFLGALAVSTVTGLGAVRLVVGPQPRTFVQAPVVAELTPTPNA
MAV_5248|M.avium_104                ---MNRRQFLGSLAASVVAGVGAARLIVDPQPRTFAQTPAAAIPTSGPTA
MAB_2590|M.abscessus_ATCC_1997      --MFDRRRFLTLLAGAAAAGASFIEYVS-----------AAADPGTAAGS
                                                                                      

MMAR_4371|M.marinum_M               ----------IGSLTGHV---TRADDQSCAVVKCVALTFDDGP-SPFTDR
MUL_0184|M.ulcerans_Agy99           ----------IGSLTGHV---TRADDQSCAVVKCVALTFDDGP-SPFTDR
Mb1126|M.bovis_AF2122/97            ----------VGGLSGRV---TRAENLSCSVIKCVALTFDDGP-GPYTDR
Rv1096|M.tuberculosis_H37Rv         ----------VGGLSGRV---TRAENLSCSVIKCVALTFDDGP-GPYTDR
Mflv_2063|M.gilvum_PYR-GCK          ---------VITVFTAAP--TAAAGPVDCAAVPCVALTFDDGP-GPHTDR
Mvan_4651|M.vanbaalenii_PYR-1       ---------LVGGFIAAVPAPAAADSVDCARVKCVALTFDDGP-GPFTDR
MSMEG_5023|M.smegmatis_MC2_155      ---------NSRTFQVAG----ALVHRVSTPEKVVALTLDDGP-TDATRV
MLBr_02649|M.leprae_Br4923          -AGVLPPPPTSARIPLPGGGVLSKIPGRGD---LLALTVDDGVNTEVVRS
MAV_5248|M.avium_104                PQALLPPPPLSARIPLPGGGALMKIPGEGD---LLALTVDDGVNSEVVRA
MAB_2590|M.abscessus_ATCC_1997      SNSGLP------RVPLPGGGTLTALPSRTDGQRLLALTLDDGTDANVIAA
                                                 .                    :***.***        

MMAR_4371|M.marinum_M               LLQILKDNDAKATFFLIG--NKVAANPAAAKRIAEAG-MEIGSHTWEHPN
MUL_0184|M.ulcerans_Agy99           LLQILKDNDAKATFFLIG--NKVAANPAAAKRIAEAG-MEIGSHTWEHPN
Mb1126|M.bovis_AF2122/97            LLHILTDNDAKATFFLIG--NKVAANPAGARRIADAG-MEIGSHTWEHPN
Rv1096|M.tuberculosis_H37Rv         LLHILTDNDAKATFFLIG--NKVAANPAGARRIADAG-MEIGSHTWEHPN
Mflv_2063|M.gilvum_PYR-GCK          LLDVLRAQGAKATFFVIG--EKVAADPAATRRITGAG-MQVGNHTWQHLD
Mvan_4651|M.vanbaalenii_PYR-1       LLQTLRANNAEATFFLIG--DKVAADPAAARRIVDAG-MEIGNHTWSHPD
MSMEG_5023|M.smegmatis_MC2_155      VLRTLAAARVPATFYLTG--RELEAAPDLGAAIAAAG-HEIGNHSFSHRR
MLBr_02649|M.leprae_Br4923          YVQFVKDTDIRLTFFVNGVYDSWTDNMSMLRPLVESGQIQLGNHTWSHPD
MAV_5248|M.avium_104                YTQFAKDTGVRLTYFVNGVYDSWTENLQLLRPLVDSGQIQLGNHTWSHPD
MAB_2590|M.abscessus_ATCC_1997      YTQLARDTGMRLTYFVNGVNAGWTQNAPMLRPLVDSGQIQLGNHTWSHPN
                                                *::: *              :. :*  ::*.*::.*  

MMAR_4371|M.marinum_M               MTTIPEADIAGQFSRANDAIKAATGRTP-TLYRPAGGLSNAAVRQTAEKF
MUL_0184|M.ulcerans_Agy99           MTTIPEADIAGQFSRANDAIKAATGRTP-TLYRPAGGLSNAAVRQTAAKY
Mb1126|M.bovis_AF2122/97            MTTIPPEDIPGQFSRANDVIAAATGRTP-TLYRPAGGLSNDAVRQAAAKV
Rv1096|M.tuberculosis_H37Rv         MTTIPPEDIPGQFSRANDVIAAATGRTP-TLYRPAGGLSNDAVRQAAAKV
Mflv_2063|M.gilvum_PYR-GCK          MTTLAPPDVAAQFARATEAIAAATGQRT-PLARTGFGAIDDSVLAEAGRQ
Mvan_4651|M.vanbaalenii_PYR-1       LTAIPPQELPAQLSRATEVLERATGERP-TLMRPPFGAVDDAVLAAAGSQ
MSMEG_5023|M.smegmatis_MC2_155      MVLMSSKTVASELERTDAAIRATGYTGP-ITFRPPYGKKLWSLPRYLAEH
MLBr_02649|M.leprae_Br4923          LTAMTKSEIATQLNRNDDFLKKNYGIAAQPYWRPPYAKHNATVDAVAVDL
MAV_5248|M.avium_104                LTTLTKEQVAEQLSRNDAFLKKTYGIGAKPYWRPPYAKRNAAVDAVAADL
MAB_2590|M.abscessus_ATCC_1997      LTTLTAEQIADQMARNTKFLVNTYGVDPAPYFRPPYGKHNAATDSVTRGL
                                    :. :.   :. :: *    :       .    *.  .    :        

MMAR_4371|M.marinum_M               GQAEILWDVIPFDWANDSNTAATRYMLMRQIKPGSVVLFHDTYSS---TV
MUL_0184|M.ulcerans_Agy99           GQAEILWDVIPFDWANDSNTAATRYMLMRQIKPGSVVLFHDTYSS---TV
Mb1126|M.bovis_AF2122/97            GQAEILWDVIPFDWINDSNTAATRHMLMTQIKPGSVVLFHDTYSS---TV
Rv1096|M.tuberculosis_H37Rv         GQAEILWDVIPFDWINDSNTAATRHMLMTQIKPGSVVLFHDTYSS---TV
Mflv_2063|M.gilvum_PYR-GCK          GLTAVNWDVNPRDWHHDADPDAIRDAVLTQVRPGAVVLLHDTVAA---TV
Mvan_4651|M.vanbaalenii_PYR-1       GLAVVNWDVIPLDWENDTDIAATRAALTEQIRPNSVVLLHDTFAS---TV
MSMEG_5023|M.smegmatis_MC2_155      DRISVTWDVEP-DSATEPTADEIVAQTVDQVRPGSIILLHAMYGSRGPTR
MLBr_02649|M.leprae_Br4923          GYTVPTLWSGSLSDSTLITEDYIVKMADQYFTPQAIVIGHLNHLP---VT
MAV_5248|M.avium_104                GYQVPTLWSGSLSDSTLITEDYILQMADQYFTPQAIVIGHLNHLP---VT
MAB_2590|M.abscessus_ATCC_1997      GYGPPVLWYGSLSDSGVVTPEYIVDMARKYFNPQAIVIGHLNHPP---VT
                                    .         . .                 . * :::: *    .   . 

MMAR_4371|M.marinum_M               DLVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSRDNGPPVDELRDIPP
MUL_0184|M.ulcerans_Agy99           DLVYQFIPVLKANGYRLVTVSELLGPRAPGNSYGSRDNGPPVDELRDIPP
Mb1126|M.bovis_AF2122/97            DVVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSRENGPPVNELRDIPA
Rv1096|M.tuberculosis_H37Rv         DVVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSRENGPPVNELRDIPA
Mflv_2063|M.gilvum_PYR-GCK          GAMADVVPALRARGYHLVTVSQLLGPLTPGSLYGSRERA-----------
Mvan_4651|M.vanbaalenii_PYR-1       DLMAEFVPVLRANGYHLVTVSQMIGPRPPGSLYGTPP-------------
MSMEG_5023|M.smegmatis_MC2_155      AALPRIISELQSAGYRFVTVSQLIGMS-----------------------
MLBr_02649|M.leprae_Br4923          HVYPQLIDIIRSRHLRTVTLNDVFLTTS----------------------
MAV_5248|M.avium_104                HVYPQLVDIIRERNLRTVTLNDVFLKTP----------------------
MAB_2590|M.abscessus_ATCC_1997      TVYRQLLDVIGERQLRTVTLNDVYQH------------------------
                                         .:  :     : **:.::                           

MMAR_4371|M.marinum_M               SDIPPLPNTPSPKPMPNFPITDIAGQNSGGPNNGA
MUL_0184|M.ulcerans_Agy99           SDIPPLPNTPSPKPMPNFPITDIAGQNSGGPNNGA
Mb1126|M.bovis_AF2122/97            SEIPPLPNTSSPKPMSNFPITDIAGQNSGGPNNGA
Rv1096|M.tuberculosis_H37Rv         SEIPPLPNTSSPKPMPNFPITDIAGQNSGGPNNGA
Mflv_2063|M.gilvum_PYR-GCK          -----------------------------------
Mvan_4651|M.vanbaalenii_PYR-1       -----------------------------------
MSMEG_5023|M.smegmatis_MC2_155      -----------------------------------
MLBr_02649|M.leprae_Br4923          -----------------------------------
MAV_5248|M.avium_104                -----------------------------------
MAB_2590|M.abscessus_ATCC_1997      -----------------------------------