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M. bovis AF2122 / 97 Mb1126 (-)

annotation: glycosyl hydrolase
coordinates: 1225757 - 1226632
length: 291

VPKRPDNQTWRYWRTVTGVVVAGAVLVVGGLSGRVTRAENLSCSVIKCVALTFDDGPGPYTDRLLHILTD
NDAKATFFLIGNKVAANPAGARRIADAGMEIGSHTWEHPNMTTIPPEDIPGQFSRANDVIAAATGRTPTL
YRPAGGLSNDAVRQAAAKVGQAEILWDVIPFDWINDSNTAATRHMLMTQIKPGSVVLFHDTYSSTVDVVY
QFIPVLKANGYRLVTVSELLGPRAPGSSYGSRENGPPVNELRDIPASEIPPLPNTSSPKPMSNFPITDIA
GQNSGGPNNGA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1126--100% (291)glycosyl hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2063-1e-6250.88% (226) polysaccharide deacetylase
M. tuberculosis H37RvRv1096-1e-17199.66% (291) glycosyl hydrolase
M. leprae Br4923MLBr_01950-1e-13980.76% (291) carbohydrate degrading enzyme
M. abscessus ATCC 19977MAB_1240-1e-10465.48% (281) glycosylhydrolase
M. marinum MMMAR_4371-1e-14785.91% (291) glycosyl hydrolase
M. avium 104MAV_1218-1e-14483.51% (291) carbohydrate degrading enzyme
M. smegmatis MC2 155MSMEG_5023-3e-2233.49% (212) chitooligosaccharide deacetylase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0184-1e-14785.57% (291) glycosyl hydrolase
M. vanbaalenii PYR-1Mvan_4651-2e-7460.09% (218) polysaccharide deacetylase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2063|M.gilvum_PYR-GCK          MTSESGALDDAHRRQARPIRRLGAVVLGVITVFTAAP--TAAAGPVDCAA
Mvan_4651|M.vanbaalenii_PYR-1       MTSGSGAQYDTRGARARRIR-SAAILLGLVGGFIAAVPAPAAADSVDCAR
Mb1126|M.bovis_AF2122/97            MPKRPDNQTWRYWRTV-----TGVVVAGAVLVVGGLSGRVTRAENLSCSV
Rv1096|M.tuberculosis_H37Rv         MPKRPDNQTWRYWRTV-----TGVVVAGAVLVVGGLSGRVTRAENLSCSV
MMAR_4371|M.marinum_M               MRKRPDNQAWRYWRMV-----VGVVAAVAVLVIGSLTGHVTRADDQSCAV
MUL_0184|M.ulcerans_Agy99           MRKRPDDQAWRYWRMV-----VGVVAAVAVLVIGSLTGHVTRADDQSCAV
MAV_1218|M.avium_104                MAKRPDTLAWRYWRTV-----VGVLAAVAVLVIGGLTGHVTRADDLSCSV
MLBr_01950|M.leprae_Br4923          MLKRPDTQAWRYSRTV-----FGVVAAGAVLVIGALTGHVTRADDMSCAQ
MAB_1240|M.abscessus_ATCC_1997      MLSKRDVFRWTMVAAA-----VGSLIAAAIVVTDKQR---AFAEPVDCQR
MSMEG_5023|M.smegmatis_MC2_155      MRRRVLTVCLALVLCV-----VVVLAGGYWLSNSRTFQVAGALVHRVSTP
                                    *              .        :                      .  

Mflv_2063|M.gilvum_PYR-GCK          VPCVALTFDDGPGPHTDRLLDVLRAQGAKATFFVIGEKVAADPAATRRIT
Mvan_4651|M.vanbaalenii_PYR-1       VKCVALTFDDGPGPFTDRLLQTLRANNAEATFFLIGDKVAADPAAARRIV
Mb1126|M.bovis_AF2122/97            IKCVALTFDDGPGPYTDRLLHILTDNDAKATFFLIGNKVAANPAGARRIA
Rv1096|M.tuberculosis_H37Rv         IKCVALTFDDGPGPYTDRLLHILTDNDAKATFFLIGNKVAANPAGARRIA
MMAR_4371|M.marinum_M               VKCVALTFDDGPSPFTDRLLQILKDNDAKATFFLIGNKVAANPAAAKRIA
MUL_0184|M.ulcerans_Agy99           VKCVALTFDDGPSPFTDRLLQILKDNDAKATFFLIGNKVAANPAAAKRIA
MAV_1218|M.avium_104                VKCVALTFDDGPGPFDERLLQILKDNDAKATFFLIGNKVAANPAGAKRIA
MLBr_01950|M.leprae_Br4923          VKCIALTFDDGPGPYTDRLVQILKDNDAKATFFLIGNKVATNPAGAKRIV
MAB_1240|M.abscessus_ATCC_1997      EKCVALTFDDGPSPFTDRLLAILRANGAHSTFFEIGNKVQRDPAGAKRVV
MSMEG_5023|M.smegmatis_MC2_155      EKVVALTLDDGPTDATRVVLRTLAAARVPATFYLTGRELEAAPDLGAAIA
                                       :***:****      ::  *    . :**:  * ::   *     :.

Mflv_2063|M.gilvum_PYR-GCK          GAGMQVGNHTWQHLDMTTLAPPDVAAQFARATEAIAAATGQRTPLARTGF
Mvan_4651|M.vanbaalenii_PYR-1       DAGMEIGNHTWSHPDLTAIPPQELPAQLSRATEVLERATGERPTLMRPPF
Mb1126|M.bovis_AF2122/97            DAGMEIGSHTWEHPNMTTIPPEDIPGQFSRANDVIAAATGRTPTLYRPAG
Rv1096|M.tuberculosis_H37Rv         DAGMEIGSHTWEHPNMTTIPPEDIPGQFSRANDVIAAATGRTPTLYRPAG
MMAR_4371|M.marinum_M               EAGMEIGSHTWEHPNMTTIPEADIAGQFSRANDAIKAATGRTPTLYRPAG
MUL_0184|M.ulcerans_Agy99           EAGMEIGSHTWEHPNMTTIPEADIAGQFSRANDAIKAATGRTPTLYRPAG
MAV_1218|M.avium_104                DAGMEIGNHTWEHPNMTTIPTEDVAAQFTRANDAIHAATGRTPNLYRPAG
MLBr_01950|M.leprae_Br4923          DAGMEIGSHTWEHPNMTMLSTEDIADQFSRANHAITVATGRTPTLWRPAG
MAB_1240|M.abscessus_ATCC_1997      EAGMELGSHTWEHPNMTTIPPEAIAGQLSKASDAIEAATGQRPKLFRTAG
MSMEG_5023|M.smegmatis_MC2_155      AAGHEIGNHSFSHRRMVLMSSKTVASELERTDAAIRATGYTGPITFRPPY
                                     ** ::*.*::.*  :. :.   :. :: ::  .:  :    .   *.  

Mflv_2063|M.gilvum_PYR-GCK          GAIDDSVLAEAGRQGLTAVNWDVNPRDWHHDADPDAIRDAVLTQVRPGAV
Mvan_4651|M.vanbaalenii_PYR-1       GAVDDAVLAAAGSQGLAVVNWDVIPLDWENDTDIAATRAALTEQIRPNSV
Mb1126|M.bovis_AF2122/97            GLSNDAVRQAAAKVGQAEILWDVIPFDWINDSNTAATRHMLMTQIKPGSV
Rv1096|M.tuberculosis_H37Rv         GLSNDAVRQAAAKVGQAEILWDVIPFDWINDSNTAATRHMLMTQIKPGSV
MMAR_4371|M.marinum_M               GLSNAAVRQTAEKFGQAEILWDVIPFDWANDSNTAATRYMLMRQIKPGSV
MUL_0184|M.ulcerans_Agy99           GLSNAAVRQTAAKYGQAEILWDVIPFDWANDSNTAATRYMLMRQIKPGSV
MAV_1218|M.avium_104                GLSNPVVRQTAGQLGLAEILWDVIPFDWANDSNTAATRYMLMTYIKPGSV
MLBr_01950|M.leprae_Br4923          GLSNEAVRQVAGRYGQAEILWDVIPFDWTNDSDTVATRCMLMMQIKPGSV
MAB_1240|M.abscessus_ATCC_1997      GLINDQVLAEAKKQGLADINWDVIPFDWANDSNTDATRAILMSQIKPGSV
MSMEG_5023|M.smegmatis_MC2_155      GKKLWSLPRYLAEHDRISVTWDVEP-DSATEPTADEIVAQTVDQVRPGSI
                                    *     :       .   : *** * *   :.            ::*.::

Mflv_2063|M.gilvum_PYR-GCK          VLLHDTVAA---TVGAMADVVPALRARGYHLVTVSQLLGPLTPGSLYGSR
Mvan_4651|M.vanbaalenii_PYR-1       VLLHDTFAS---TVDLMAEFVPVLRANGYHLVTVSQMIGPRPPGSLYGTP
Mb1126|M.bovis_AF2122/97            VLFHDTYSS---TVDVVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSR
Rv1096|M.tuberculosis_H37Rv         VLFHDTYSS---TVDVVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSR
MMAR_4371|M.marinum_M               VLFHDTYSS---TVDLVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSR
MUL_0184|M.ulcerans_Agy99           VLFHDTYSS---TVDLVYQFIPVLKANGYRLVTVSELLGPRAPGNSYGSR
MAV_1218|M.avium_104                VLFHNTYSS---TVDLVYQFIPVLKANGYRLVTVSELLGPRAPGSSYGSR
MLBr_01950|M.leprae_Br4923          VLFHDTYSS---TVDLVYQFIPVLKANGYRLVTVTELLGPRAPGSSYGRR
MAB_1240|M.abscessus_ATCC_1997      VLFHDTYSS---TVDLVEQFLPVLRANGYHAVTVTQLLGPREPGTSYGSR
MSMEG_5023|M.smegmatis_MC2_155      ILLHAMYGSRGPTRAALPRIISELQSAGYRFVTVSQLIGMS---------
                                    :*:*   .:   *   :  .:. *:: **: ***::::*           

Mflv_2063|M.gilvum_PYR-GCK          ERA----------------------------------------------
Mvan_4651|M.vanbaalenii_PYR-1       P------------------------------------------------
Mb1126|M.bovis_AF2122/97            ENGPPVNELRDIPASEIPPLPNTSSPKPMSNFPITDIAGQNSGGPNNGA
Rv1096|M.tuberculosis_H37Rv         ENGPPVNELRDIPASEIPPLPNTSSPKPMPNFPITDIAGQNSGGPNNGA
MMAR_4371|M.marinum_M               DNGPPVDELRDIPPSDIPPLPNTPSPKPMPNFPITDIAGQNSGGPNNGA
MUL_0184|M.ulcerans_Agy99           DNGPPVDELRDIPPSDIPPLPNTPSPKPMPNFPITDIAGQNSGGPNNGA
MAV_1218|M.avium_104                ENGPPVNGLRDIPASDIPKLPDTPSPKPMPNFPITDIPGQNSGGPNNGA
MLBr_01950|M.leprae_Br4923          ENGPPVNQLHDIPANLIPALPNTSSPKPMPNFPITDISGQNSGGSNDGA
MAB_1240|M.abscessus_ATCC_1997      ENGPPVNLLKDIPASEIPPLPNTPSPLPATNIPITDLPNQGAGGPAVGQ
MSMEG_5023|M.smegmatis_MC2_155      -------------------------------------------------