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MVPSQSHPAKTPRKQLKPPIEAVQSHYDRSNEFFKLWLDPSMTYSCAYFERPDLTLEEAQRAKRDLALSK LGLEPGMTLLDIGCGWGSTMLHAIEKYDVNVIGLTLSANQLAHNKLKFAEIDHTRTDRTKDVRLQGWEQF DEPVDRIISLGAFEHFADGAGDAGFERYDSFFKMCYDVLPDDGRMLLHTIIVPDAKETKELGLTTPMSLL RFIKFILTEIFPGGRLPKISQVDHYSSNAGFTVERYHRIGSHYVPTLNAWAAALEAHKDEAIALQGRQIY DTYMHYLTGCSDLFRDRYTDVCQFTLVK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02426 | cmaA2 | - | 100% (308) | cyclopropane mycolic acid synthase |
| M. leprae Br4923 | MLBr_02459 | umaA2 | 2e-96 | 59.18% (294) | Mycolic acid synthase |
| M. leprae Br4923 | MLBr_01900 | mmaA1 | 7e-84 | 52.38% (294) | methyl mycolic acid synthase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0515c | cmaA2 | 1e-143 | 79.87% (298) | cyclopropane-fatty-acyl-phospholipid synthase 2 CMAA2 |
| M. gilvum PYR-GCK | Mflv_3304 | - | 1e-101 | 60.75% (293) | cyclopropane-fatty-acyl-phospholipid synthase |
| M. tuberculosis H37Rv | Rv0503c | cmaA2 | 1e-143 | 79.87% (298) | cyclopropane-fatty-acyl-phospholipid synthase 2 CMAA2 |
| M. abscessus ATCC 19977 | MAB_3881 | - | 8e-93 | 57.29% (295) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. marinum M | MMAR_0831 | cmaA2 | 1e-144 | 81.29% (294) | cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 |
| M. avium 104 | MAV_4647 | - | 1e-121 | 68.81% (295) | cyclopropane-fatty-acyl-phospholipid synthase 2 |
| M. smegmatis MC2 155 | MSMEG_1205 | - | 1e-105 | 62.50% (288) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. thermoresistible (build 8) | TH_2761 | - | 1e-101 | 62.37% (287) | PUTATIVE cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. ulcerans Agy99 | MUL_4575 | cmaA2 | 1e-143 | 80.95% (294) | cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 |
| M. vanbaalenii PYR-1 | Mvan_3025 | - | 1e-100 | 60.41% (293) | cyclopropane-fatty-acyl-phospholipid synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0515c|M.bovis_AF2122/97 ------MTSQGDT---TSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTY
Rv0503c|M.tuberculosis_H37Rv ------MTSQGDT---TSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTY
MAV_4647|M.avium_104 ------MTSQGE-------TQLKPPVEAVRSHYDKSNEFFKLWLDPSMTY
MMAR_0831|M.marinum_M ------MGKRGDQPSLP--DQLSPPVEAVQSHYDRSNEFFKLFLDPSMTY
MUL_4575|M.ulcerans_Agy99 ------MGKRGDQPSLP--DQLSPPVEAVQSHYDRSNEFFKLFLDPSMTY
MLBr_02426|M.leprae_Br4923 ------MVPSQSHPAKTPRKQLKPPIEAVQSHYDRSNEFFKLWLDPSMTY
MSMEG_1205|M.smegmatis_MC2_155 MKETPQKSNIAVKVGAPPGERHGSTADEVRSHYDLSNEFFRLWQDPTQTY
TH_2761|M.thermoresistible__bu ----------------------------VRSHYDLSNEFFRLWQDPTQTY
Mflv_3304|M.gilvum_PYR-GCK ------MSDTPNGS-----ADLQPHFDDVQSHYDLSDDFYRLFLDPTQTY
Mvan_3025|M.vanbaalenii_PYR-1 ------MPETTSGS-----ADLQPHFEDVQSHYDLSDDFYRLFLDPTQTY
MAB_3881|M.abscessus_ATCC_1997 -------------M-----SKLTPKFSDVQAHYDLSDDFFALFLDPSRTY
*::*** *::*: *: **: **
Mb0515c|M.bovis_AF2122/97 SCAYFERPDMTLEEAQYAKRKLALDKLNLEPGMTLLDIGCGWGSTMRHAV
Rv0503c|M.tuberculosis_H37Rv SCAYFERPDMTLEEAQYAKRKLALDKLNLEPGMTLLDIGCGWGSTMRHAV
MAV_4647|M.avium_104 SCGYWEEGAKTLEEAQYAKRKLALDKLNLEPGMTLLDIGCGWGSTMRHAV
MMAR_0831|M.marinum_M SCAYFERPDMTLEQAQYAKRKLSLDKLNLEPGMTLLDIGCGWGSTMRHAI
MUL_4575|M.ulcerans_Agy99 SCAYFERPDMTLEQAQYAKRKLSLDKLNLEPGMTLLDIGCGWGSTMRHAI
MLBr_02426|M.leprae_Br4923 SCAYFERPDLTLEEAQRAKRDLALSKLGLEPGMTLLDIGCGWGSTMLHAI
MSMEG_1205|M.smegmatis_MC2_155 SCAYFERDDMTLEEAQMAKVDLALGKLGLQPGMTLLDIGCGWGSTIMRAV
TH_2761|M.thermoresistible__bu SCAYFERDDMTLEEAQLAKVDLALGKLGLRPGMTLLDIGCGWGSTIMRAV
Mflv_3304|M.gilvum_PYR-GCK SCAYFERDDMTLEEAQRAKIDLALGKLGLEPGMTLLDIGCGWGGTLLRAL
Mvan_3025|M.vanbaalenii_PYR-1 SCAYFERDDMTLEEAQIAKIDLSLGKLGLQPGMTLLDIGCGWGATLLRAL
MAB_3881|M.abscessus_ATCC_1997 SCAYFEPETLTLEQAQQAKIDLALGKLNLEPGMTLLDVGCGWGSTMKRAL
**.*:* ***:** ** .*:*.**.*.*******:*****.*: :*:
Mb0515c|M.bovis_AF2122/97 AEYDVNVIGLTLSENQYAHDKAM-FDEVDSP---RRKEVRIQGWEEF-DE
Rv0503c|M.tuberculosis_H37Rv AEYDVNVIGLTLSENQYAHDKAM-FDEVDSP---RRKEVRIQGWEEF-DE
MAV_4647|M.avium_104 EEYDVDVIGLTLSENQYAHCVAE-FDKMDSP---RRKEVRIQGWEEFPDE
MMAR_0831|M.marinum_M EEYDVNVIGLTLSENQLVHDERK-FADMDSP---RHKEVRLQGWEQF-DE
MUL_4575|M.ulcerans_Agy99 EEYDVNVIGLTLSENQLVHDERK-FADMDSP---RHKEVRLQSWEQF-DE
MLBr_02426|M.leprae_Br4923 EKYDVNVIGLTLSANQLAHNKLK-FAEIDHTRTDRTKDVRLQGWEQF-DE
MSMEG_1205|M.smegmatis_MC2_155 EKYDVNVIGLTLSHNQRAHIEQR-FAESDSP---RRKEVRLQPWEDF-DE
TH_2761|M.thermoresistible__bu DEHDVDVIGLTLSENQRRHIEEHWFANSDSP---RRKEVRLQGWEDF-DE
Mflv_3304|M.gilvum_PYR-GCK EKYDVNVIGLTLSRNQQAHVQKV-LDEHDSP---RSKTVLLQGWEQF-DQ
Mvan_3025|M.vanbaalenii_PYR-1 DKYDVNVIGLTLSRNQQAHVQKR-LDAHGSG---RSKRVLLAGWEQF-DE
MAB_3881|M.abscessus_ATCC_1997 EHYDVNVIGLTLSKNQFAYVNTL-LDSAGSS---RNYEVRLAGWEEF-EG
.:**:******* ** : : . * * : **:* :
Mb0515c|M.bovis_AF2122/97 PVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLHTITI
Rv0503c|M.tuberculosis_H37Rv PVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLHTITI
MAV_4647|M.avium_104 PIDRIVSLGAFEHFADGAGDAGYERYATFFKKYYDLLPDDGRMLLHSIVV
MMAR_0831|M.marinum_M PVDRIVSLGAFEHFADGAGDASWERYDRFFKMCYNVLPDDGRMLLHTIIV
MUL_4575|M.ulcerans_Agy99 PVDRIVSLGAFEHFADGAGDASWERYDRFFKMCYNVLPDDGRMLLHTIIV
MLBr_02426|M.leprae_Br4923 PVDRIISLGAFEHFADGAGDAGFERYDSFFKMCYDVLPDDGRMLLHTIIV
MSMEG_1205|M.smegmatis_MC2_155 PVDRIVSIGAFEHFG-------FEKYADYFKKTFELMPDDGVMLLHTIVS
TH_2761|M.thermoresistible__bu PVDRIVSIGAFEHFG-------FDNYDFYFKKTYDLLPDDGVMLLHTIVS
Mflv_3304|M.gilvum_PYR-GCK PVDRIVSIGAFEHFG-------SDRYDEFFRRAYSVLPDDGVMLLHTIVK
Mvan_3025|M.vanbaalenii_PYR-1 PVDRIVSIGAFEHFG-------RDRYDEFFKKAYQVLPDGGVMMLHTIIK
MAB_3881|M.abscessus_ATCC_1997 TVDRIVSIGAFEHFG-------HERYDSFFAMAHRVLPSDGKMLLHTIVS
.:***:*:******. :.* :* . : *..* *:**:*
Mb0515c|M.bovis_AF2122/97 PDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWK
Rv0503c|M.tuberculosis_H37Rv PDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWK
MAV_4647|M.avium_104 PTREEGNAMGLKVNMTLLRFISFILKEIYPGGKLPQVNLVDKYATDAGFK
MMAR_0831|M.marinum_M PDAKEAKELGLTAPMSLMRFIKFILTEIFPGGRLPQIPQIDEYSSRAGFK
MUL_4575|M.ulcerans_Agy99 PDAKEAKELGLTAPMSLMRFIKFILTEIFPGGRLPQIPQIDEYSSRAGFK
MLBr_02426|M.leprae_Br4923 PDAKETKELGLTTPMSLLRFIKFILTEIFPGGRLPKISQVDHYSSNAGFT
MSMEG_1205|M.smegmatis_MC2_155 TSKEEVEEMGLPTTMSLMRFFRFIVTEIYPGGRIPLIAMVEDRATEAGFT
TH_2761|M.thermoresistible__bu TSREEVAELGLPTTMSLLRFFKFIVDEIYPGGRIPLIAQVEDAATNAGFR
Mflv_3304|M.gilvum_PYR-GCK PSDEEFAERKLPLTMTKLKFFKFIMDEIFPGGMLPKVDDVEKHATKASFK
Mvan_3025|M.vanbaalenii_PYR-1 PTDEEFADRGLKLTMSIVRFSKFIMDEIFPGGDLPKPTTVAEHATKAGFR
MAB_3881|M.abscessus_ATCC_1997 HHPDEWKRMGIPLLMSRVRFIYFIGTEIFPGGRLPSVPMVDKHAALAGFH
.* : *: ::* ** **:*** :* : :: *.:
Mb0515c|M.bovis_AF2122/97 VERYHRIGANYVPTLNAWADALQAHKDEAIALKGQETYDIYMHYLRGCSD
Rv0503c|M.tuberculosis_H37Rv VERYHRIGANYVPTLNAWADALQAHKDEAIALKGQETYDIYMHYLRGCSD
MAV_4647|M.avium_104 IERHHFIGKNYVPTLTAWGDALEAHKEEAIALKGQETYDIYLKYLRGCAE
MMAR_0831|M.marinum_M VERYHRIGSNYVPTLNSWAQALQANQEKAIELQGQEVYDIYMHYLTGCSD
MUL_4575|M.ulcerans_Agy99 VERYHRIGSNYVPTLNSWAQALQANQEKAIELQGQEVYDIYMHYLTGCSD
MLBr_02426|M.leprae_Br4923 VERYHRIGSHYVPTLNAWAAALEAHKDEAIALQGRQIYDTYMHYLTGCSD
MSMEG_1205|M.smegmatis_MC2_155 VTRKQRLRPHYVRTLDTWAANLEAKKDQAIEITSEEVYERYLKYLKGCAD
TH_2761|M.thermoresistible__bu ITQKQRLRPHYVKTLDAWAANLEANRRAAIEITSEEVYDRYLRYLTGCSD
Mflv_3304|M.gilvum_PYR-GCK VNRIQPLRLHYARTLQIWAASLESRRDDAIAIQSEEVYDRYMKYLTGCAE
Mvan_3025|M.vanbaalenii_PYR-1 LTREQRLREHYAKTLDIWADALRKREDDAVAIQSREDYDRYMKYLTGCAD
MAB_3881|M.abscessus_ATCC_1997 ITRHHSLQPHYARTLDCWATNLAAHEDEAISVQSQEVYDRYIKYLTGCAE
: : : : :*. ** *. * .. *: : ..: *: *::** **::
Mb0515c|M.bovis_AF2122/97 LFRDKYTDVCQFTLVK---
Rv0503c|M.tuberculosis_H37Rv LFRDKYTDVCQFTLVK---
MAV_4647|M.avium_104 LFRDGYTNVCQFTMVK---
MMAR_0831|M.marinum_M LFRDHYTDVCQFTMVK---
MUL_4575|M.ulcerans_Agy99 LFRDHYTDVCQFTMVK---
MLBr_02426|M.leprae_Br4923 LFRDRYTDVCQFTLVK---
MSMEG_1205|M.smegmatis_MC2_155 LFRDGYTDVCQFTCEKSVA
TH_2761|M.thermoresistible__bu LFAKGYTDVCQFTCRKGQ-
Mflv_3304|M.gilvum_PYR-GCK LFTEGYTDVCQFTLAK---
Mvan_3025|M.vanbaalenii_PYR-1 LFRDGYTDICQFTLEK---
MAB_3881|M.abscessus_ATCC_1997 GFREGWIDVVQFTCEK---
* . : :: *** *