For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSNELPGEWSGERRSFFSRTPVNDNPDKVVYRRGFVTRHQVTGWRFVMRRIASGIALHDTRMLVDPLRTQ SRSVLVGALLVITGLIGCFVFSFIRPNGAAGNNAVLADRSTAALYVRVGDELHPVLNLTSARLIVGRSVN PITVKSSELDRFPRGNLIGIPGAPERMVQNTTHDANWTVCDVVSGEGGHAAHSMGVTVIAGPPDSHGMRA AVLGSAHGVLVDAPSERGGSTWLLWDGKRSEIDLADHAVTDALGFGVGFAEVPAPRPIGAGLFNAIPEAP PLKAPVIPNAGATPSFGVRAPIGAVVVSFGLAALGKNPYDSVRYYAVLPDGLQPISPVLAAILRNINSYG LQQPPRLGADEVDKLPVSRMLDTERYPEQQISLIDAGYAPVSCAYWSKPAGAATSFLSLMSGAALPVPDA ARAVELVSAPSRGDSSTASRVVLTPGTGYFAQTVGVGSAAPATASLFWVSDTGVRYGIDTEADARSEATA GPGKIVEALGLKLPAVPIPWSILSLFAVGPTLSRADALLEHDGLAPDTRAGRTTTAYGEHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02536 | - | - | 100% (552) | hypothetical protein MLBr_02536 |
| M. leprae Br4923 | MLBr_01544 | - | 4e-85 | 36.59% (511) | hypothetical protein MLBr_01544 |
| M. leprae Br4923 | MLBr_00054 | - | 3e-67 | 34.49% (519) | hypothetical protein MLBr_00054 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0291 | - | 0.0 | 70.83% (552) | hypothetical protein Mb0291 |
| M. gilvum PYR-GCK | Mflv_0328 | - | 1e-167 | 58.52% (540) | hypothetical protein Mflv_0328 |
| M. tuberculosis H37Rv | Rv0283 | - | 0.0 | 70.83% (552) | hypothetical protein Rv0283 |
| M. abscessus ATCC 19977 | MAB_2233c | - | 1e-149 | 54.51% (532) | hypothetical protein MAB_2233c |
| M. marinum M | MMAR_0542 | - | 0.0 | 70.58% (554) | hypothetical protein MMAR_0542 |
| M. avium 104 | MAV_4870 | - | 0.0 | 70.31% (549) | hypothetical protein MAV_4870 |
| M. smegmatis MC2 155 | MSMEG_0616 | - | 0.0 | 61.54% (533) | hypothetical protein MSMEG_0616 |
| M. thermoresistible (build 8) | TH_3098 | - | 7e-80 | 76.09% (184) | PUTATIVE protein of unknown function DUF690 |
| M. ulcerans Agy99 | MUL_1205 | - | 0.0 | 69.86% (554) | hypothetical protein MUL_1205 |
| M. vanbaalenii PYR-1 | Mvan_0412 | - | 1e-176 | 61.94% (536) | hypothetical protein Mvan_0412 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0291|M.bovis_AF2122/97 MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTGWRFVMR
Rv0283|M.tuberculosis_H37Rv MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTGWRFVMR
MMAR_0542|M.marinum_M MTTNEPDGEWAGARRSFTSRTPVNDNPDKVEYRRGFVTRHQVTGWRFVMR
MUL_1205|M.ulcerans_Agy99 MTTNEPDGEWAGARRSFTSRTPVNDNPDKVEYRRGFVTRHQVTGWRFVMR
MLBr_02536|M.leprae_Br4923 MTSNELPGEWSGERRSFFSRTPVNDNPDKVVYRRGFVTRHQVTGWRFVMR
MAV_4870|M.avium_104 MTANNDPD----DRRSFTSRTPVNDNPDQVQYRRGFVTRHQVSGWRFVMR
MSMEG_0616|M.smegmatis_MC2_155 ----MTGPVNPDDRRSFSSRTPVNENPDGVQYRRGFVTRHQVSGWRFVMR
TH_3098|M.thermoresistible__bu ----VTAPE--DDRRSFSSRTPVNENPDRVVYRRGFVTRHQVSGWRFMMR
Mflv_0328|M.gilvum_PYR-GCK ----MSGAD--GDRRSFTSRTPTNENPDRVSFRRGFVTRHQVSGWRFMVR
Mvan_0412|M.vanbaalenii_PYR-1 ----MSAPE--EERRSFASRTPTNGNPDRVTYRRGFVTRHQVTGWRFVMR
MAB_2233c|M.abscessus_ATCC_199 -MSDNRDNNANSERRAFASRTPASENPEPLKYRRGFVTGHQVTGWRFVMR
**:* ****.. **: : :****** ***:****::*
Mb0291|M.bovis_AF2122/97 RIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQ
Rv0283|M.tuberculosis_H37Rv RIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQ
MMAR_0542|M.marinum_M RIASGIALHDTRMLVDPLRTQSRSVLMGVLIFITGLVGCFVFSLIRPNGQ
MUL_1205|M.ulcerans_Agy99 RIASGIALHDTRMLVDPLRTQSRSVLMGVLIFITGLVGCFVFSLIRPNGQ
MLBr_02536|M.leprae_Br4923 RIASGIALHDTRMLVDPLRTQSRSVLVGALLVITGLIGCFVFSFIRPNGA
MAV_4870|M.avium_104 RIASGIALHDTRMLVDPLRTQSRAVAMGAVLLVTGLAGCFVFSLIRPNGT
MSMEG_0616|M.smegmatis_MC2_155 RIASGVALHDTRMLVDPLRTQSRAVLTGALILVTGLVGCFIFSLFRPGGV
TH_3098|M.thermoresistible__bu RIASGVALHDTRMLVDPLRTQTRSVLVGVLILITGLAGCFVFSLIRPAGV
Mflv_0328|M.gilvum_PYR-GCK RMASGVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPAGD
Mvan_0412|M.vanbaalenii_PYR-1 RIASGVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPSGA
MAB_2233c|M.abscessus_ATCC_199 RIASGVALHDARMLVDPLRTQSRAFGMGAVVVVTGLVGCFVFSLLRPSGI
*:*:*:****:**********:*:. *.::.:*** *.*:**::** *
Mb0291|M.bovis_AF2122/97 AGSNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTEL
Rv0283|M.tuberculosis_H37Rv AGSNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTEL
MMAR_0542|M.marinum_M VGSNAVLADRSTAALYVRVGDTLHPVLNLTSARLIVGHPVNPTTVKSTEL
MUL_1205|M.ulcerans_Agy99 VGSNAVLADRSTAALYVRVGDTLHPVLNLTSARLIVGHPVNPTTVKSTEL
MLBr_02536|M.leprae_Br4923 AGNNAVLADRSTAALYVRVGDELHPVLNLTSARLIVGRSVNPITVKSSEL
MAV_4870|M.avium_104 AGTNAVLADRSTAALYVRVGDDLHPVLNLTSARLIVGKPVNPTTVKSAEL
MSMEG_0616|M.smegmatis_MC2_155 PGNNAILADRSTSALYVRVGEQLHPVLNLTSARLISGSPDNPTMVKTSEI
TH_3098|M.thermoresistible__bu AGEDAVLADRSTAALYVKVGEQLHPVLNLTSARLITGRAEDPKTVKTSEI
Mflv_0328|M.gilvum_PYR-GCK VGTDSILAERDTAALYVRLGDQVHPVLNLASARLITGRPDNPAMVKSSEL
Mvan_0412|M.vanbaalenii_PYR-1 AGTDAVLADRDTAALYVRLGEQLHPVLNLTSARLIAGRPDNPAMVKSSEL
MAB_2233c|M.abscessus_ATCC_199 AGTDPILADRSTAALYVRVGDNLHPVLNLTSARLIAGKAADPTMVKSTQL
* :.:**:*.*:****::*: :******:***** * . .* **::::
Mb0291|M.bovis_AF2122/97 DQFPRGNLIGIPGAPERMVQNTSTDANWTVCDGLNAPSRGG--ADGVGVT
Rv0283|M.tuberculosis_H37Rv DQFPRGNLIGIPGAPERMVQNTSTDANWTVCDGLNAPSRGG--ADGVGVT
MMAR_0542|M.marinum_M DRFPRGNLIGIPGAPERMVQSEARDSDWTVCDAISSGSQGGSAAHSTGVT
MUL_1205|M.ulcerans_Agy99 DRFPRGNLIGIPGAPERMVQSEARDSDWTVCDAISSGSQGGSAAHSTGVT
MLBr_02536|M.leprae_Br4923 DRFPRGNLIGIPGAPERMVQNTTHDANWTVCDVVSG--EGGHAAHSMGVT
MAV_4870|M.avium_104 DRFPRGNLLGIPGAPERMVQNPSTDANWTVCDSVSEPAPGGHGAHSTGVT
MSMEG_0616|M.smegmatis_MC2_155 DKFPRGNLLGIPGAPERMVQNAATDAEWTVCDAVGG--------ANPGVT
TH_3098|M.thermoresistible__bu DKFPRGNLLGIPGAPERMTQNPARDADWMVCDAVSG--------PHPXXX
Mflv_0328|M.gilvum_PYR-GCK DELPRGNMLGIPGAPGRMAVNTTRDAYWTVCDAAAG--------AVTGVT
Mvan_0412|M.vanbaalenii_PYR-1 DQFPRGNLIGIPGAPERMVANTTRDAYWTVCDAATG--------STAGVT
MAB_2233c|M.abscessus_ATCC_199 DKFPRGNLIGIPGAPERMVQAKATDAAWAVCEAGQTS------TDNRSVT
*.:****::****** **. : *: * **:
Mb0291|M.bovis_AF2122/97 VIAGPLEDTGARAAALGPGQAVLVDS----GAGTWLLWDGKRSPIDLADH
Rv0283|M.tuberculosis_H37Rv VIAGPLEDTGARAAALGPGQAVLVDS----GAGTWLLWDGKRSPIDLADH
MMAR_0542|M.marinum_M VIAGSPEPSGHRATALGAGQVILVND----GTSSWLLWDGKRSRMDLADH
MUL_1205|M.ulcerans_Agy99 VIAGSPEPSGHRATALGAGQVILVND----GTSSWLLWDGKRSRMDLADH
MLBr_02536|M.leprae_Br4923 VIAGPPDSHGMRAAVLGSAHGVLVDAPSERGGSTWLLWDGKRSEIDLADH
MAV_4870|M.avium_104 VIAGRPDSSGARAAALPSQQAILAER----DGGTWLLWNGRRSQINLADH
MSMEG_0616|M.smegmatis_MC2_155 VIAGPLGADGERAAPLPPDHAVLVHSDAEPNPGDWLLWDGKRSPIDLADR
TH_3098|M.thermoresistible__bu FSLG-----------CPP------------------KWPAHGGPLSLALP
Mflv_0328|M.gilvum_PYR-GCK VIAGAPDDTGERATVLPDGHAVLAENNGR----TWLLWDGRRSAIDLADR
Mvan_0412|M.vanbaalenii_PYR-1 VIAGRPADGGERAAALPAGHAVLAENGGR----TWLLWDGKRSPIDLADR
MAB_2233c|M.abscessus_ATCC_199 VIAGPLDTDGDKAADLPRDRAAVVSS----EAGTWLLWDGKRSALNLGDV
. * * .: . :.*.
Mb0291|M.bovis_AF2122/97 AVTSGLGLGA---DVPAPRIIASGLFNAIPEAPPLTAPIIPDAGNPASFG
Rv0283|M.tuberculosis_H37Rv AVTSGLGLGA---DVPAPRIIASGLFNAIPEAPPLTAPIIPDAGNPASFG
MMAR_0542|M.marinum_M AVTNALGFGT---DLPAPRPIAPGLFNAIPEAAPLAAPAIPDAGNPAAFA
MUL_1205|M.ulcerans_Agy99 AVTNALGFAT---DLPAPRPIAPGLFNAIPEAAPLAAPAIPDAGNPAAFA
MLBr_02536|M.leprae_Br4923 AVTDALGFGVGFAEVPAPRPIGAGLFNAIPEAPPLKAPVIPNAGATPSFG
MAV_4870|M.avium_104 AVTNALGLTENNSELPAPRPIALGLFNAIPEAPSLSAPGIPNAGAPAPFA
MSMEG_0616|M.smegmatis_MC2_155 AVTDALGLGG---QALAPRPIAAGLFNAVPAAPALTAPVIPDAGAAPQFE
TH_3098|M.thermoresistible__bu NVRES---------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK AVAGGVGIGV---GVAAPQPIATGLFNAIPEAPALITPVIPNAGLPSDLG
Mvan_0412|M.vanbaalenii_PYR-1 AVTGGLGIGV---DSAAPQPISVGLFNAIPEGPPLVTPAIPGAGSPSAAP
MAB_2233c|M.abscessus_ATCC_199 AVTSALGFTAP----PAVRPVTTRLLNAIPEAPALVIPAIAGAGAPTSYP
* .
Mb0291|M.bovis_AF2122/97 VPA--PIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLAAILRN
Rv0283|M.tuberculosis_H37Rv VPA--PIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLAAILRN
MMAR_0542|M.marinum_M VPG--PIGSVVQAYTLGD------NSIQYYAVLPDGLQPISPVLAAILRN
MUL_1205|M.ulcerans_Agy99 VPG--PIGSVVQAYTLGD------NSIQYYAVLPDGLQPISPVLAAIVRN
MLBr_02536|M.leprae_Br4923 VRA--PIGAVVVSFGLAALGKNPYDSVRYYAVLPDGLQPISPVLAAILRN
MAV_4870|M.avium_104 VPA--PIGAVVVSYTLDQSS---SGAPRYYAVLPDGLQQISPVLAAILRN
MSMEG_0616|M.smegmatis_MC2_155 LSLPVPVGAVVVAYDADN-------TARYYAVLSDGLQPISPVLAAILRN
TH_3098|M.thermoresistible__bu --------------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK LPEPFPVGSVVVSYDEDN-------TLRHYVVLTDGLQPISPVVAAILRN
Mvan_0412|M.vanbaalenii_PYR-1 LPEPLPIGAVVVAYDADN-------AIRHYVVLADGLQAVSPVVAAILRN
MAB_2233c|M.abscessus_ATCC_199 LPVAAPIGSVLVSYSTDN-------TPVHYAVLTDGVQQISPVIASALRN
Mb0291|M.bovis_AF2122/97 NNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAY
Rv0283|M.tuberculosis_H37Rv NNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAY
MMAR_0542|M.marinum_M TNSYGLQQPPRIGADDVAKLPVSRMLDTTRYPATPMHLVDTESNPITCAY
MUL_1205|M.ulcerans_Agy99 TNSYGLQQPPRIGADDVAKLPVSRMLDTTRYPATPMHLVDTESNPITCAY
MLBr_02536|M.leprae_Br4923 INSYGLQQPPRLGADEVDKLPVSRMLDTERYPEQQISLIDAGYAPVSCAY
MAV_4870|M.avium_104 TNSYGLDQPPRLGADAVAKLPVSRMLDTARYPDQHVSLVDTAKSPVTCAY
MSMEG_0616|M.smegmatis_MC2_155 TDSHGFAQPPRLGPDEVARTPMSRGLDTSAYPDNPVTLVEASAHPVTCAH
TH_3098|M.thermoresistible__bu --------------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK SNSWGLASPPRLDADLVARTPQAEVVDVDAYPAERVTLVDTAAEPVICAA
Mvan_0412|M.vanbaalenii_PYR-1 SNSYGLAQPPRLDADVVARIPEAAGVDNAAYPSDRVTLVDVAADPVTCAQ
MAB_2233c|M.abscessus_ATCC_199 ANSYGLEQPPRLTADQIAHLPTSSAIDTRVFPNVAVKPLAADEDPVLCTR
Mb0291|M.bovis_AF2122/97 WSKPVGAATSSLTLLAGSALPVPDAVHTVELVGAG---NGGVATRVALAA
Rv0283|M.tuberculosis_H37Rv WSKPVGAATSSLTLLAGSALPVPDAVHTVELVGAG---NGGVATRVALAA
MMAR_0542|M.marinum_M WSKPVGATTSSLTLLSGAALPVPDAVHTVDLVGGGSQ-NGAVATRVALAP
MUL_1205|M.ulcerans_Agy99 WSKPVGATTSSLTLLSGAALPVPGAVHTVDLVGGGSQ-NGAVATRVALAP
MLBr_02536|M.leprae_Br4923 WSKPAGAATSFLSLMSGAALPVPDAARAVELVSAPSRGDSSTASRVVLTP
MAV_4870|M.avium_104 WSKPAGAATSSLNLLSGSALPIAESIRPVDLVGGGSPQNGPVATRVALPP
MSMEG_0616|M.smegmatis_MC2_155 WTKPSDAAESSLSVLSGAVLPLAEGLHTVDLVGAGA---GGAANRVALTP
TH_3098|M.thermoresistible__bu --------------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK WSEHEGAQESSMELRSGAALPVADGVSTVALVSAGAP--GGPANQVALPQ
Mvan_0412|M.vanbaalenii_PYR-1 WAKPEGAQDASLTLRTGAVLPVADGARTVELVSSGTP--GGPADRVALPP
MAB_2233c|M.abscessus_ATCC_199 FTRTADATADSWSLLAGSVLPLSDSVHTVQLISPAAT-----PTRVAIAP
Mb0291|M.bovis_AF2122/97 GTGYFTQTVGGGPDAPGAGSLFWVSDTGVRYGIDNEPQG----VAGGGKA
Rv0283|M.tuberculosis_H37Rv GTGYFTQTVGGGPDAPGAGSLFWVSDTGVRYGIDNEPQG----VAGGGKA
MMAR_0542|M.marinum_M GTGYFTQTAGGGPAAPPTGSLFWVSDTGVRYGIDTEGE-------GGRKT
MUL_1205|M.ulcerans_Agy99 GTGYFTQTAGGGPAAPPTGSLFWVSDTGVRYGIDTEGE-------GGRKT
MLBr_02536|M.leprae_Br4923 GTGYFAQTVGVGSAAPATASLFWVSDTGVRYGIDTEADARSEATAGPGKI
MAV_4870|M.avium_104 GTGYFTQTASGGAGSPGAGSLFWVSDTGVRYGIDNEAEHS---AAGHGKT
MSMEG_0616|M.smegmatis_MC2_155 GTGYFVQTVGAEPGSPTAGSMFWVSDTGVRYGIDTAED---------DKV
TH_3098|M.thermoresistible__bu --------------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK GTGYFVDN---------AGSLFWLSDTGVRYGIDTGADA------DGADT
Mvan_0412|M.vanbaalenii_PYR-1 GTGYFVDS---------AGSLFWISDTGVRYGIDTGS--------DGVDT
MAB_2233c|M.abscessus_ATCC_199 GTGYLVQPGG-------RGGYQWISDTGVRYGIDTEAE--------GDKT
Mb0291|M.bovis_AF2122/97 VEALGLNPPPVPIPWSVLSLFVPGPTLSRADALLAHDTLVPDSRPARPVS
Rv0283|M.tuberculosis_H37Rv VEALGLNPPPVPIPWSVLSLFVPGPTLSRADALLAHDTLVPDSRPARPVS
MMAR_0542|M.marinum_M VEALGLQDPPVLIPWSVLSLFAPGPTLSRADALMAHDGLAPDSKPGRPAS
MUL_1205|M.ulcerans_Agy99 VEALGLQDPPVLIPWSVLSLFAPGPTLSRADALMAHDGLAPDSKPGRPAS
MLBr_02536|M.leprae_Br4923 VEALGLKLPAVPIPWSILSLFAVGPTLSRADALLEHDGLAPDTRAGRTTT
MAV_4870|M.avium_104 VEALGLSGSPLPIPWSVLSLFAKGPTLSRADALLAHDGLPPDQAPGRVAA
MSMEG_0616|M.smegmatis_MC2_155 VAALGLSTSPLPVPWSVLSQFAAGPALSRGDALVAHDAVSTNPNSARMEA
TH_3098|M.thermoresistible__bu --------------------------------------------------
Mflv_0328|M.gilvum_PYR-GCK VAALGLTTTPLPIPSSVLSLFAAGPTLSRGDALLAHDTLAPNPSPARVEA
Mvan_0412|M.vanbaalenii_PYR-1 VAALGLTTAPLPIPSSVLSQFAVGPTLSRTDALLAHDSLAPNPAPARLET
MAB_2233c|M.abscessus_ATCC_199 LEALGLHKPALTIPSSILDLFASGPSLSRADALLARDSLTPTDRQAVPVQ
Mb0291|M.bovis_AF2122/97 AE----GGYR---
Rv0283|M.tuberculosis_H37Rv AE----GGYR---
MMAR_0542|M.marinum_M AE----GEPR---
MUL_1205|M.ulcerans_Agy99 AE----GGPR---
MLBr_02536|M.leprae_Br4923 AY----GEHR---
MAV_4870|M.avium_104 AAPQAEGAPR---
MSMEG_0616|M.smegmatis_MC2_155 SR-----------
TH_3098|M.thermoresistible__bu -------------
Mflv_0328|M.gilvum_PYR-GCK LP----GLENP--
Mvan_0412|M.vanbaalenii_PYR-1 TS----ALEKP--
MAB_2233c|M.abscessus_ATCC_199 TDTQLAQNAQESR