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M. smegmatis MC2 155 MSMEG_6058 (-)

annotation: cadmium transporting P-type ATPase
coordinates: 6125473 - 6127611
length: 712

ADLTVVSDAAGRMRVHAPWFRGDAVRAVAIEQAVDQVPGVRAVHAYPRTGSVVVWYSPRRCDRDAVRSAM
TAAAGVARHLVPGRSPRSADVHNADIVRMAIGAVALILLGIRRYGFARPPLLGSTSRTLATGATIITGYP
FLRGALRTLTGNRSAGTDVLVSAATVASLVLRENVVALTVLWLLNIGEYLQDLTLRRTRRAIANLLQGTQ
DTVWLRLADRTEIEVAVDGVRVGDQVVIHEQVAIVVDGVVCDGEAIVDQSAITGENLPVAVGPGSKVYAG
SVVVRGRLVVTAEAVGSHTTIGRIITRVEEAQQHRAPIQTVGENFSRRFVPASFLLSAATLVVTRDVRRA
MTMLLVACPCAVGLATPTVISAAIGNGARRGILIKGGSHLEQAGRVDAMVFDKTGTLTLGRPIVTNVVAF
HKDWEPEQVLAYAASSEIHARHPLAEAVIRSTRERHIVIPPHEECEVLVGLGMRTRADGRTLLLGSPSLL
RQEKVRVTSRAAAWVDKLRKRAETPLLLAVDGKLVGLISLRDEVRPEAAEVLRALRTAGVRRMVMLTGDH
PDAAAAVADELGITEWRAEVLPEDKLAVVRRLHAEGHTVAVIGDGVNDAPALAAADIGIAMGLGGTDVAV
ETADVALASDDLRRLLDVRDLGARAVDVIQQNYAMSIAVNAIGLAVGAGGALSPVLAAVLHNASSVAVVA
NSARLIRYEID*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6058--100% (712)cadmium transporting P-type ATPase
M. smegmatis MC2 155MSMEG_5014-1e-9639.30% (542) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5403cadA2e-7933.66% (618) cadmium-translocating P-type ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3298ctpC0.077.23% (716) metal cation-transporting P-type ATPase C CtpC
M. gilvum PYR-GCKMflv_3179-3e-9535.52% (611) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv3270ctpC0.077.23% (716) metal cation-transporting P-type ATPase C CtpC
M. leprae Br4923MLBr_00747ctpC0.075.81% (711) putative cation transport ATPase
M. abscessus ATCC 19977MAB_4853c-2e-9435.01% (617) cation-transporting ATPase G
M. marinum MMMAR_1271ctpC0.076.89% (714) metal cation-transporting p-type ATPase C CtpC
M. avium 104MAV_4235cadA0.077.86% (709) cadmium-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-1e-8534.13% (756) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_2616ctpC0.076.47% (714) metal cation-transporting p-type ATPase C CtpC
M. vanbaalenii PYR-1Mvan_3641-2e-9536.07% (596) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3298|M.bovis_AF2122/97            ------------------MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEE
Rv3270|M.tuberculosis_H37Rv         ------------------MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEE
MMAR_1271|M.marinum_M               MTLAIVKEVPAGADGDDTTDLVVLSDAAGRMRVRADWVRGNSRRAVAVEE
MUL_2616|M.ulcerans_Agy99           MTLAIVKEVPAGADGDDTTDLVVLSDAAGRMRVRADWVRGNSRRAVAVEE
MAV_4235|M.avium_104                ---------------MEDPALQVISDAAGRMRVSVGWVRADSRRAVAVEE
MLBr_00747|M.leprae_Br4923          MTLAMAEQIAT----ADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEE
MSMEG_6058|M.smegmatis_MC2_155      -----------------MADLTVVSDAAGRMRVHAPWFRGDAVRAVAIEQ
Mflv_3179|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3641|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_4853c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4361|M.thermoresistible__bu      ----------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVVATVN
                                                                                      

Mb3298|M.bovis_AF2122/97            AVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIP
Rv3270|M.tuberculosis_H37Rv         AVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIP
MMAR_1271|M.marinum_M               AVAKQDGVRVVHAYPRTGSVVVWYSPRRCDRAAVLEAIGGAKHVAAELIP
MUL_2616|M.ulcerans_Agy99           AVAKQDGVRVVHAYPRTGSVVVWYSPRRCDRAAVLEAIGGAKHVAAELIP
MAV_4235|M.avium_104                AVAKCDGVRVVHAYPRTGSVVIWYSPRRCDRSAVLAAIGEAAHVAAELIP
MLBr_00747|M.leprae_Br4923          AIAKCNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIP
MSMEG_6058|M.smegmatis_MC2_155      AVDQVPGVRAVHAYPRTGSVVVWYSPRRCDRDAVRSAMTAAAGVARHLVP
Mflv_3179|M.gilvum_PYR-GCK          -----------------------------------MSDACGCGSDEPR--
Mvan_3641|M.vanbaalenii_PYR-1       -----------------------------------MSDACGCGNDEPRG-
MAB_4853c|M.abscessus_ATCC_199      -----------------------------------MSDACGCGHDEPATG
TH_4361|M.thermoresistible__bu      FATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGAATGA
                                                                            .         

Mb3298|M.bovis_AF2122/97            ARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATG
Rv3270|M.tuberculosis_H37Rv         ARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATG
MMAR_1271|M.marinum_M               ARAPHSTEIRNTDVLRMVIGGAALALLGVRRYVFARPPLLGPSGRMVATG
MUL_2616|M.ulcerans_Agy99           AHAPHSTEIRNTDVLRMVIGGAALALLGVRRYVFARPPLLGPSGRMVATG
MAV_4235|M.avium_104                ARAPHSSEIRNADVLRMVIGGAALALLGVRRYVFARPPLLGPSGRLFATG
MLBr_00747|M.leprae_Br4923          TRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTTSRLVASG
MSMEG_6058|M.smegmatis_MC2_155      GRSPRSADVHNADIVRMAIGAVALILLGIRRYGFARPPLLGSTSRTLATG
Mflv_3179|M.gilvum_PYR-GCK          SAEEQEREPERLWQITELQFAALSGVLLLAALIANLVGAADPVVLTLEAA
Mvan_3641|M.vanbaalenii_PYR-1       DDDDHDGEPEKLWQIKELQFAALSGVFLLAALITGVLDAAEPVVLALEAV
MAB_4853c|M.abscessus_ATCC_199      DEVDGEREPERLWEVSELRFAAVAGVVLLAGYVVGWTGGSHPVEIGLYAA
TH_4361|M.thermoresistible__bu      AGDDHDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLALTLTSP
                                         . : ..         .    :. :                 . : 

Mb3298|M.bovis_AF2122/97            VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATVASLILR----------
Rv3270|M.tuberculosis_H37Rv         VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATVASLILR----------
MMAR_1271|M.marinum_M               VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATIASLILR----------
MUL_2616|M.ulcerans_Agy99           VTIFTGYPFLRGALRSLRSGKAG-TDALVSAATIASLILR----------
MAV_4235|M.avium_104                VTVFTGYPFLRGALRSLRSGRAG-TDALVSAATVASLVLR----------
MLBr_00747|M.leprae_Br4923          VTIFTGYPFLRGALR---FGKTG-TDALVSAATIASLILR----------
MSMEG_6058|M.smegmatis_MC2_155      ATIITGYPFLRGALRTLTGNRSAGTDVLVSAATVASLVLR----------
Mflv_3179|M.gilvum_PYR-GCK          ALLAGAYTFVPSTLGRLAKGKIG-VGTLMTIAAVGAVLLG----------
Mvan_3641|M.vanbaalenii_PYR-1       ALVAGAYTFVPSTLKRLVTGKIG-VGTLMTIAAVGAVILG----------
MAB_4853c|M.abscessus_ATCC_199      ALAIGAYTFVPSTLRRLARGKIG-VGTLMTIAAIGAVILG----------
TH_4361|M.thermoresistible__bu      VVVWGAWPFHRAAVANLRHGTAT-MDTLISLGVTAAYLWSLWALFFTAAG
                                    .    .:.*  .::     .     ..*:: .. .: :            

Mb3298|M.bovis_AF2122/97            --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
Rv3270|M.tuberculosis_H37Rv         --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
MMAR_1271|M.marinum_M               --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
MUL_2616|M.ulcerans_Agy99           --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
MAV_4235|M.avium_104                --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
MLBr_00747|M.leprae_Br4923          --------------------ENVVALAVLWLLNIGEYLQDLTLRRTRRAI
MSMEG_6058|M.smegmatis_MC2_155      --------------------ENVVALTVLWLLNIGEYLQDLTLRRTRRAI
Mflv_3179|M.gilvum_PYR-GCK          --------------------EVGEAAMLAFLFSISEGLEEYSLARTRRGL
Mvan_3641|M.vanbaalenii_PYR-1       --------------------EVGEAAMLAFLFSISEGLEEYSVARTRRGL
MAB_4853c|M.abscessus_ATCC_199      --------------------EVGEAAMLAFLFSISEGLEEYALARTRRGL
TH_4361|M.thermoresistible__bu      MPGMTMTFTLLPADTGEPHIYLEVAAAVTTFIIAGRYFEARAKRQSGAAL
                                                            *  :  ::  .. ::  :  ::  .:

Mb3298|M.bovis_AF2122/97            SELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIP
Rv3270|M.tuberculosis_H37Rv         SELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIP
MMAR_1271|M.marinum_M               SELLRGNQDTAWIRLTD---GPEAGTEVQVPIDSVQIGDEVVVHDHVAIP
MUL_2616|M.ulcerans_Agy99           SELLRGNQDTAWIRLTD---GPEAGTEVQVPIDSVQIGDEVVVHDHVAIP
MAV_4235|M.avium_104                SELLRGSQDTAWIRLEH--------NEIQVATDTLQIGDEVVVHDHVAIP
MLBr_00747|M.leprae_Br4923          SALLSGTQDTAWIRLTD---GPQAGTEIQVPIGTVQIGDEVVVHEHVAIP
MSMEG_6058|M.smegmatis_MC2_155      ANLLQGTQDTVWLRLAD-------RTEIEVAVDGVRVGDQVVIHEQVAIV
Mflv_3179|M.gilvum_PYR-GCK          RALLSLVPDEATVRRDG--------TETTIAPTELRIGDLMVVKPGERVA
Mvan_3641|M.vanbaalenii_PYR-1       RALLSLVPDEATVLRDG--------TEKTVAPTDLQIGDRMLVKPGERVA
MAB_4853c|M.abscessus_ATCC_199      RALLSLAPEEATVLRDG--------TETTITATELQVGDTMLVRPGERVA
TH_4361|M.thermoresistible__bu      RALLDMGANDVAVLRDG--------AEKRVPIGELHVGDVFVVRPGEKIA
                                      **    : . :             *  :.   :::** .:::    : 

Mb3298|M.bovis_AF2122/97            VDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHAV
Rv3270|M.tuberculosis_H37Rv         VDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHAV
MMAR_1271|M.marinum_M               VDGEVVDGEAIVNQSAITGENLPVSVVAGATVHAGSVVVRGRLVVRAQAV
MUL_2616|M.ulcerans_Agy99           VDGEVVDGEAIVNQSAITGENLPVSVVAGATVHAGSVVVRGRLVVRAQAV
MAV_4235|M.avium_104                VDGEVIDGEAIVDQSAITGENLPVSVVVGMPVHAGSVVVRGRLVVRARAV
MLBr_00747|M.leprae_Br4923          VDGEVIDGEAVVNQSAITGENLPVSVMAGSHVHAGSVVVRGRLMVRASAV
MSMEG_6058|M.smegmatis_MC2_155      VDGVVCDGEAIVDQSAITGENLPVAVGPGSKVYAGSVVVRGRLVVTAEAV
Mflv_3179|M.gilvum_PYR-GCK          TDGIITRGRTALDLSAITGESVPVEAGPGDEVFAGSINGAGALEVEVSTT
Mvan_3641|M.vanbaalenii_PYR-1       TDGIIRHGRTALDVSAITGESVPVEAGPGDEVFAGSINGTGALEVEVSTT
MAB_4853c|M.abscessus_ATCC_199      TDGTITAGRTALNTSAITGESVPVEAGPGDEVFAGSINGNGVLQVRVSAT
TH_4361|M.thermoresistible__bu      TDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVRATRV
                                    .** :  *.: :: * :***.:** .  *  * ..::   * : * .  .

Mb3298|M.bovis_AF2122/97            GNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLIT-
Rv3270|M.tuberculosis_H37Rv         GNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLIT-
MMAR_1271|M.marinum_M               GNQTTIGRIITRVEEAQNDRAPIQTVGENFSRRFVPTSFIVSAITLLVT-
MUL_2616|M.ulcerans_Agy99           GNQTTIGRIITRVEEAQNDRAPIQTVGENFSRRFVPTSFIVSAITLLVT-
MAV_4235|M.avium_104                GNQTTIGRIITRVEEAQHDRAPIQTVGENFSRRFVPTSFIVSAITLAVT-
MLBr_00747|M.leprae_Br4923          GKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAITLAIT-
MSMEG_6058|M.smegmatis_MC2_155      GSHTTIGRIITRVEEAQQHRAPIQTVGENFSRRFVPASFLLSAATLVVT-
Mflv_3179|M.gilvum_PYR-GCK          AEDNSLARIVRIVEAEQSRKGAAQRLADRIAKPLVPAVMIAAALIAVAGS
Mvan_3641|M.vanbaalenii_PYR-1       AEDNSLARIVRIVEAEQSRKGASQRLADRIAKPLLPGIMIVAALIAVIGS
MAB_4853c|M.abscessus_ATCC_199      AADNSLARIVAIVEAEQSRKGASQRLADRIAKPLVPAIMITAAAIAVLGS
TH_4361|M.thermoresistible__bu      GADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSALTLAGWL
                                    . .. :.::   *   *  :.  * :.:..:  ::*  :  :*       

Mb3298|M.bovis_AF2122/97            --------GDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKG
Rv3270|M.tuberculosis_H37Rv         --------GDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKG
MMAR_1271|M.marinum_M               --------GDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKG
MUL_2616|M.ulcerans_Agy99           --------GDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKG
MAV_4235|M.avium_104                --------GDVRRAMTMLLIACPCAVGLATPTAISAAIGNGARRGILIKG
MLBr_00747|M.leprae_Br4923          --------KDVRRTMTVLLIACPCAVGLATPTAISAAIGNGARRGILIKG
MSMEG_6058|M.smegmatis_MC2_155      --------RDVRRAMTMLLVACPCAVGLATPTVISAAIGNGARRGILIKG
Mflv_3179|M.gilvum_PYR-GCK          LLGDP--ATWIERALVVLVAASPCALAISVPVTVVAAIGAASKLGALVKG
Mvan_3641|M.vanbaalenii_PYR-1       LLGDP--ATWIERALVVLVAASPCALAISVPVTVVAAIGAASKLGVLVKG
MAB_4853c|M.abscessus_ATCC_199      VFGDP--LVWIERALVVLVAASPCALAISVPVTVVAAIGAASKLGVLVKG
TH_4361|M.thermoresistible__bu      LLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGILIKG
                                              .  ::.:*: *.***:.::.*..: .. * .:: * *:**

Mb3298|M.bovis_AF2122/97            GSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASS
Rv3270|M.tuberculosis_H37Rv         GSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASS
MMAR_1271|M.marinum_M               GSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIIAMHKDWEPEQVLAYAASS
MUL_2616|M.ulcerans_Agy99           GSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIIAMHKDWEPEQVLAYAASS
MAV_4235|M.avium_104                GSHLEQAGQVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASS
MLBr_00747|M.leprae_Br4923          GSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSPEQVLAYAASS
MSMEG_6058|M.smegmatis_MC2_155      GSHLEQAGRVDAMVFDKTGTLTLGRPIVTNVVAFHKDWEPEQVLAYAASS
Mflv_3179|M.gilvum_PYR-GCK          GAALEALGRIRGVALDKTGTLTANRPTVIEVATTPD-VTPEHVLDLAAAV
Mvan_3641|M.vanbaalenii_PYR-1       GAALEGLGRIRGVALDKTGTLTANRPAVIDVATTNG-ATREQVLDVAAAL
MAB_4853c|M.abscessus_ATCC_199      GAALEALGVVRTIALDKTGTLTANRPTVIEVAATAG-ATGERVLSAAAAL
TH_4361|M.thermoresistible__bu      PQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADG-LSETELLRLAGAV
                                       **    :  : :*****:* .:  * .: .        .:*  *.: 

Mb3298|M.bovis_AF2122/97            EIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGS
Rv3270|M.tuberculosis_H37Rv         EIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGS
MMAR_1271|M.marinum_M               EIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGS
MUL_2616|M.ulcerans_Agy99           EIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGS
MAV_4235|M.avium_104                EIHSRHPLAEAVIRSTEERHITIPPHEECEVLVGLGMRTWADGRTLLLGS
MLBr_00747|M.leprae_Br4923          EIHSRHPLAEAVIRSTEERHISIPPHEECEVLVGLGMRTWADGRTLLLGS
MSMEG_6058|M.smegmatis_MC2_155      EIHARHPLAEAVIRSTRERHIVIPPHEECEVLVGLGMRTRADGRTLLLGS
Mflv_3179|M.gilvum_PYR-GCK          EARSEHPLAAAILAAAGTVTP----AADVEAVTGAGLTGHRDGHRIRLGR
Mvan_3641|M.vanbaalenii_PYR-1       ESRSEHPLAAAILAATDDVIP----ATDVEAVTGTGLTGHRDGHTLRLGR
MAB_4853c|M.abscessus_ATCC_199      ESRSEHPLAAAILAAAGSVDP----ADDVEAVTSAGLTGRRGGHTLRLGR
TH_4361|M.thermoresistible__bu      EHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGHDVRVGR
                                    *  :.**:* *:   :           : *   . *:    .*: : :* 

Mb3298|M.bovis_AF2122/97            PSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRP
Rv3270|M.tuberculosis_H37Rv         PSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRP
MMAR_1271|M.marinum_M               PSLLESEQVKVSKKASEWVGKLRQQAETPLLLAVDGTLVGLISLRDEVRP
MUL_2616|M.ulcerans_Agy99           PSLLESEQVKVSKKASEWVGKLRQQAETPLLLAVDGTLVGLISLRDEVRP
MAV_4235|M.avium_104                PSLLQAEKVKVSKKAKEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRP
MLBr_00747|M.leprae_Br4923          PSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLISLRDEVRP
MSMEG_6058|M.smegmatis_MC2_155      PSLLRQEKVRVTSRAAAWVDKLRKRAETPLLLAVDGKLVGLISLRDEVRP
Mflv_3179|M.gilvum_PYR-GCK          PGWLDRGP------LTAEVTRMQQAGATAVLVEDNGQVIGAIAVRDELRP
Mvan_3641|M.vanbaalenii_PYR-1       PGWLDPGP------LAGDVTRMQQAGATAVLVEHNGQVIGAIAVRDELRP
MAB_4853c|M.abscessus_ATCC_199      PGWIDPGS------LAPDVARMQQGGATAVLVEEDGQLLGAIAVRDELRP
TH_4361|M.thermoresistible__bu      LAWLGLSAG---DRLRNAAAQAEAAGHTPVWVAVDGRIAGVIVVSDTVKD
                                     . :              . : .    *.: .  :* : * * : * :: 

Mb3298|M.bovis_AF2122/97            EAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPEDKL
Rv3270|M.tuberculosis_H37Rv         EAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPEDKL
MMAR_1271|M.marinum_M               EAAEVLTKLRDNGVRRIVMLTGDHPDIAKVVAEELGIDEWRAEVMPEDKL
MUL_2616|M.ulcerans_Agy99           EAAEVLTKLRDNGVRRIVMLTGDHPDIAKVVAEELGIDEWRAEVMPEDKL
MAV_4235|M.avium_104                EAAGVLKKLRANGIRRIVMLTGDHPDIAAVVADELGIDEWRAEVMPEDKL
MLBr_00747|M.leprae_Br4923          EAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMPEDKL
MSMEG_6058|M.smegmatis_MC2_155      EAAEVLRALRTAGVRRMVMLTGDHPDAAAAVADELGITEWRAEVLPEDKL
Mflv_3179|M.gilvum_PYR-GCK          EATEVITQLRRDGYQ-VAMLTGDNHATAAALAREVGIDTVHADLRPEDKA
Mvan_3641|M.vanbaalenii_PYR-1       EAAEVVAQLRRDGYH-VAMLTGDNHATAAALARDVGIEDVHAELRPEDKA
MAB_4853c|M.abscessus_ATCC_199      EAAHVIAALHRSGYR-VAMLTGDNAATATTLARQVGIDTVHADLRPEDKA
TH_4361|M.thermoresistible__bu      HAAEAIAELRALGAT-PVLLTGDNDRAARTVAAQVGIDDVIAGVLPAEKV
                                    .*: .:  *:  *    .:****:   * .:* ::**    * : * :* 

Mb3298|M.bovis_AF2122/97            AAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVA
Rv3270|M.tuberculosis_H37Rv         AAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVA
MMAR_1271|M.marinum_M               EVVRDLQDEGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVA
MUL_2616|M.ulcerans_Agy99           EVVRDLQDEGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVA
MAV_4235|M.avium_104                AAVRDLQEEGFVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVA
MLBr_00747|M.leprae_Br4923          KVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVETADVA
MSMEG_6058|M.smegmatis_MC2_155      AVVRRLHAEGHTVAVIGDGVNDAPALAAADIGIAMGLGGTDVAVETADVA
Mflv_3179|M.gilvum_PYR-GCK          RLIEQLR-TQRPTAMVGDGVNDAPALATADLGIAMGAMGTDVAIETADVA
Mvan_3641|M.vanbaalenii_PYR-1       RLIEQLR-AQRPTAMVGDGVNDAPALATADIGIAMGAMGTDVAIETADVA
MAB_4853c|M.abscessus_ATCC_199      RIITELR-QQHPTAMVGDGVNDAPALATADLGIAMGAMGTDVAIETADVA
TH_4361|M.thermoresistible__bu      DHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIG-TGTDVAIEASDLT
                                      :  *:     ..::***:***.*** **:*:*:*  *****:*::*::

Mb3298|M.bovis_AF2122/97            LANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVL
Rv3270|M.tuberculosis_H37Rv         LANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVL
MMAR_1271|M.marinum_M               LANDDLHRLLDVRDLGGRAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVL
MUL_2616|M.ulcerans_Agy99           LANDDLHRLLDIRDLGGRAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVL
MAV_4235|M.avium_104                LSNDDLHRLLDVRDLGSRAVDVIRENYGMSIAVNAAGLIIGAGGALSPVL
MLBr_00747|M.leprae_Br4923          LANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGALSPVL
MSMEG_6058|M.smegmatis_MC2_155      LASDDLRRLLDVRDLGARAVDVIQQNYAMSIAVNAIGLAVGAGGALSPVL
Mflv_3179|M.gilvum_PYR-GCK          LMGEDLRHLPQTFTHARRARRIMLQNVGLSLGLIIVLMPLALFGVLGLAA
Mvan_3641|M.vanbaalenii_PYR-1       LMGEDLRHLPQAFTHARRARRIMLQNVGLSLGLIVVLMPLALFGVLGLAA
MAB_4853c|M.abscessus_ATCC_199      LMGEDLRHLTQALAHARRARTIMLQNVGLSLALIAVLIPLALLGILGLAA
TH_4361|M.thermoresistible__bu      LVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAAGLLNPLI
                                    *   **.   :    .  :   :  *   ::.     : :.  * *.   

Mb3298|M.bovis_AF2122/97            AAILHNASSVAVVANSSRLIRYRLDR--------------------
Rv3270|M.tuberculosis_H37Rv         AAILHNASSVAVVANSSRLIRYRLDR--------------------
MMAR_1271|M.marinum_M               AAILHNASSVAVVANSSRLIRYRLE---------------------
MUL_2616|M.ulcerans_Agy99           AAILHNASSVVVVANSSRLIRYRLE---------------------
MAV_4235|M.avium_104                AAILHNASSVAVVANSSRLIRYRLN---------------------
MLBr_00747|M.leprae_Br4923          AAVLHNASSVAVVANSSRLIRYRLD---------------------
MSMEG_6058|M.smegmatis_MC2_155      AAVLHNASSVAVVANSARLIRYEID---------------------
Mflv_3179|M.gilvum_PYR-GCK          VVLVHELAEIVVIANGVRAGRTTALTALTAQRSTNLATATAVGAPS
Mvan_3641|M.vanbaalenii_PYR-1       VVLVHELAEIVVIANGVRAGRTTPLAATPVDPAASHSGVAPVGAPS
MAB_4853c|M.abscessus_ATCC_199      VVAVHELAEIVVIANGVRAGRTQPLTAPEHANTPAAQLAQQE----
TH_4361|M.thermoresistible__bu      AGAAMAFSSVFVVSNSLRLRRFTPSR--------------------
                                    .      :.: *::*. *  *