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M. leprae Br4923 MLBr_00129 (-)

annotation: hypothetical protein MLBr_00129
coordinates: 173197 - 174453
length: 418

SPDKREFDIVLYGATGFSGKLTAEHLALSESTARIALAGRSSERLRNVRALLGPNAQDWPLIVADASQPS
TLEAMAGRAQVVLTTVGPYTRYGLPLVAACARTGTDYADLTGELMFCRNSIDLHHKQAAATGARIILACG
FDSVPSDLNVYQLYRRVIEDRTGELCDTDLVLRSFSQRWVSGGSVAAYSEAMLTTSNDPEALRLVTDPYT
LTTDRDAEPDLGPQPDFPRHRGSDLAPELAGFWTGGFVQAQFNTRIVRRSNALQNWSYGRQFRYSETMSL
GKSWAAPVASAAVTSVVAGAVGLGNKYFNRLPRRVVERVTPKSGTGPSRKTQARGHYTFETYTTTTTGAR
YMATFAHNVDAYKSTAGLLAASGLTLALDRDRLSELRGVLTPAAAMGEALLTRLPSAGVVIGTTRLS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00129--100% (418)hypothetical protein MLBr_00129

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2977-0.086.60% (418) hypothetical protein Mb2977
M. gilvum PYR-GCKMflv_2628-1e-14462.05% (419) saccharopine dehydrogenase
M. tuberculosis H37RvRv2953-0.086.60% (418) hypothetical protein Rv2953
M. abscessus ATCC 19977MAB_4339c-1e-12859.62% (416) hypothetical protein MAB_4339c
M. marinum MMMAR_1757-0.079.38% (417) hypothetical protein MMAR_1757
M. avium 104MAV_1723-1e-14965.70% (414) saccharopine dehydrogenase
M. smegmatis MC2 155MSMEG_4632-1e-14663.29% (414) saccharopine dehydrogenase
M. thermoresistible (build 8)TH_0608-1e-15063.72% (419) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_2000-0.078.90% (417) hypothetical protein MUL_2000
M. vanbaalenii PYR-1Mvan_3953-1e-14261.59% (414) saccharopine dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2628|M.gilvum_PYR-GCK          MDMSE-NDREHDIVLYGATGFVGKLTAQYLAS--AGTGARIALAGRSTDR
Mvan_3953|M.vanbaalenii_PYR-1       MSANEAHDREHDIVVYGATGFVGKLTAQYLAA--AGAGARIALAGRSTDR
TH_0608|M.thermoresistible__bu      MTAAQ---REFDIVLYGATGFVGKLTARYLAS--AGVGARIALAGRSEQK
MSMEG_4632|M.smegmatis_MC2_155      MTQ-----REFDLVLYGATGFAGKLTAQYLAG--AAGDARIALAGRSAEK
MAV_1723|M.avium_104                MTATP---REFDIVLYGATGFVGKLTAEYLAG--AAPDKRIALAGRSTEK
MAB_4339c|M.abscessus_ATCC_199      MSR------EHDIVLYGATGYVGKLTALYLAGRVEATGARIALAGRSTEK
Mb2977|M.bovis_AF2122/97            MSPAE---REFDIVLYGATGFSGKLTAEHLAH--SGSTARIALAGRSSER
Rv2953|M.tuberculosis_H37Rv         MSPAE---REFDIVLYGATGFSGKLTAEHLAH--SGSTARIALAGRSSER
MLBr_00129|M.leprae_Br4923          MSPDK---REFDIVLYGATGFSGKLTAEHLAL--SESTARIALAGRSSER
MMAR_1757|M.marinum_M               MSSAQ---REFDIVLYGATGFSGMLTGQHLAQ--RDTNARIALAGRSPQR
MUL_2000|M.ulcerans_Agy99           MSSAQ---REFEIVLYGATGFSGMLTGQHLAQ--RDTNARIALAGRSPQR
                                    *        *.::*:*****: * **. :**        ******** ::

Mflv_2628|M.gilvum_PYR-GCK          LLAVRDSLGEQAKDWPLIVADASQPSTINAMAASTRVVVTTVGPYLRYGL
Mvan_3953|M.vanbaalenii_PYR-1       LLAVRESLGEAAQDWPLLVADASQPSTLNAMAASTRVVITTVGPYLRYGL
TH_0608|M.thermoresistible__bu      LAAVRESLGEAAASWPLLTADADQPATLDELASRTQVVVTTVGPYTKYGM
MSMEG_4632|M.smegmatis_MC2_155      LQAARDSIGGAAADWPLVIADADNPSTLADMAARTRVVVTTVGPYTRYGL
MAV_1723|M.avium_104                LHAVRDSLGDAAQSWPVLQADASSPATLNEMAARTQVVITTVGPYTRYGL
MAB_4339c|M.abscessus_ATCC_199      LAAVRDACGPAARDWPLIEADTTRPATLAAMAASTQVVLTTVGPYTKYGL
Mb2977|M.bovis_AF2122/97            LRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQVVLTTVGPYTRYGL
Rv2953|M.tuberculosis_H37Rv         LRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQVVLTTVGPYTRYGL
MLBr_00129|M.leprae_Br4923          LRNVRALLGPNAQDWPLIVADASQPSTLEAMAGRAQVVLTTVGPYTRYGL
MMAR_1757|M.marinum_M               LRAVRDKLGPLASDWPLVVADASQPATLEEMATRAQVILTTVGPYTRYGL
MUL_2000|M.ulcerans_Agy99           LRAVRDKLGPLASDWPLVVADASQPATLEEMATRAQVILTTVGPYTRYGL
                                    *  .*   *  * .**:: **:  * *:  :*  ::*::****** :**:

Mflv_2628|M.gilvum_PYR-GCK          PLVAACAAAGTDYADLTGETLFVRRAIDLHHKQAVDTGARIVHACGFDSI
Mvan_3953|M.vanbaalenii_PYR-1       PLVAACAAAGTDYADLTGETLFVRECIDLYHKQAADTGARIVHACGFDSI
TH_0608|M.thermoresistible__bu      PLVAACAVAGTDYADLTGETMFIRRAIDLYHKQAADNGARIVHSCGFDSI
MSMEG_4632|M.smegmatis_MC2_155      PLVAACAAAGTDYADLTGETMFIRDSIDRYHQQAVDTGARIVHSCGFDSV
MAV_1723|M.avium_104                PLVAACAAAGTDYADLTGEAMFVRDSIDSYHKQAADTGARIVHACGFDSV
MAB_4339c|M.abscessus_ATCC_199      PLVAACAEAGTDYADLTGEVNFVRESIDVYGKQAADTGARIVHCCGFDSI
Mb2977|M.bovis_AF2122/97            PLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSI
Rv2953|M.tuberculosis_H37Rv         PLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSI
MLBr_00129|M.leprae_Br4923          PLVAACARTGTDYADLTGELMFCRNSIDLHHKQAAATGARIILACGFDSV
MMAR_1757|M.marinum_M               PLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIVLACGFDSI
MUL_2000|M.ulcerans_Agy99           PLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIVLACGFDSI
                                    ******* :**********  * * .** : :**. .****: .*****:

Mflv_2628|M.gilvum_PYR-GCK          PSDMTVFALYRQAERDGTGQLGDTNFVARSFAG-GVSGGTIASMTELARE
Mvan_3953|M.vanbaalenii_PYR-1       PSDMTVFALYRAAERDRTGELGDTNFVVRSFAG-GVSGGTVASMTELARQ
TH_0608|M.thermoresistible__bu      PSDITVYALYRRAVEDGTGELGDTNLVVRRFAG-GVSGGTAASMLEVMRT
MSMEG_4632|M.smegmatis_MC2_155      PSDLTVFALHRRATADGAGELVDTDLVLRSFAG-GVSGGTAASMIEVLRT
MAV_1723|M.avium_104                PSDLSVYALYRAARDDGAGELVDTDLVVRSFSG-GVSGGTVASMLEVLDT
MAB_4339c|M.abscessus_ATCC_199      PSDLSVYALYRRAQEDGTGELLDTTYVLSKFRG-GVSGGTAASMVEVMEA
Mb2977|M.bovis_AF2122/97            PSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRT
Rv2953|M.tuberculosis_H37Rv         PSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRT
MLBr_00129|M.leprae_Br4923          PSDLNVYQLYRRVIEDRTGELCDTDLVLRSFSQRWVSGGSVAAYSEAMLT
MMAR_1757|M.marinum_M               PSDLNVHHLYRRAAEDGTGELAETNLVLRSFSQRWASGGSVATYSEAMRT
MUL_2000|M.ulcerans_Agy99           PSDLNVHHLYRRAAEDGTGELAETNLVLRSFSQRWASGGSVATYSEAMRT
                                    ***:.*. *:*    * :*:* :*  *   *    .***: *:  *    

Mflv_2628|M.gilvum_PYR-GCK          ASLDPEARRLLNDPYTLTPDRGAEPELGPQPDARWRRGREIAPELDGYWV
Mvan_3953|M.vanbaalenii_PYR-1       ASQDPEARRLLNDPYTLTPDRAAEPELGAQPDARWRRGREIAPELDGYWV
TH_0608|M.thermoresistible__bu      ASEDPEARRLMTDPYTLSPDRAAEPELGGQPDIRWRRGGEIAPELEGYWT
MSMEG_4632|M.smegmatis_MC2_155      SSTDPAARAAMTDPYTLSPDRSREPELGDQPDVRWRRGSEIAPELAGYWT
MAV_1723|M.avium_104                ASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPCRRGRQIAPELAGVWT
MAB_4339c|M.abscessus_ATCC_199      SAEDPEVRRNAQDPYSLSPDRPAEPEVGRQREFQTLRGESVAPELTGKWL
Mb2977|M.bovis_AF2122/97            ASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPELAGFWT
Rv2953|M.tuberculosis_H37Rv         ASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPELAGFWT
MLBr_00129|M.leprae_Br4923          TSNDPEALRLVTDPYTLTTDRDAEPDLGPQPDFPRHRGSDLAPELAGFWT
MMAR_1757|M.marinum_M               ASSDPEAYRLVNDPYTLTTDRSAEPDLGPQPDFSMRRGRDLAPELAGFWT
MUL_2000|M.ulcerans_Agy99           ASSDPEAYRLVNDPYTLTTDRSAEPDLGPQPDFSMRRGRDLAPELAGFWT
                                    :: ** .     ***:*:.**  **::* * :     * .:**** * * 

Mflv_2628|M.gilvum_PYR-GCK          GAFAMALPNTRVVRRSNALLDYAYGRRFEYAELMSTGRSIGAPVLAAVAT
Mvan_3953|M.vanbaalenii_PYR-1       GAFAMALPNTRVVRRSNALLGYAYGRRFEYAEQMSTGRSVGAPLVAAMAT
TH_0608|M.thermoresistible__bu      GAFVMAVANTRIVRRTNALLDYAYGRRFEYAEQMSLGKSIAAPVAAALAT
MSMEG_4632|M.smegmatis_MC2_155      GAFAMAGPNTRIVRRSNALLDYAYGRRFAYAEQMSCGRSPAAPIAAALVT
MAV_1723|M.avium_104                AGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVG
MAB_4339c|M.abscessus_ATCC_199      GAFFMGPVNTRIVRRSNALLDWAYGTRMRYREAMSLGSSVVAPVAAAAVT
Mb2977|M.bovis_AF2122/97            GGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVT
Rv2953|M.tuberculosis_H37Rv         GGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVT
MLBr_00129|M.leprae_Br4923          GGFVQAQFNTRIVRRSNALQNWSYGRQFRYSETMSLGKSWAAPVASAAVT
MMAR_1757|M.marinum_M               GAFVQGPFNTRIVRRSNALQDWAYGRQFRYSETMSLGRSFAAPIASAAVT
MUL_2000|M.ulcerans_Agy99           GAFVQGPFNTRIVRRSNALQDWAYGKQFRYSETMSLGRSFAAPIASAAVT
                                    ..*  .  ***:***:***  ::**  : * * ** * *  **: :* . 

Mflv_2628|M.gilvum_PYR-GCK          AGNAATMQLGSRFLNRVPRAALERVLPKPGTGPNEQTRERGHYTVETYTT
Mvan_3953|M.vanbaalenii_PYR-1       AGNVATMELSSRFLDRVPRGALERILPKVGTGPSEQTRERGHYTVETYTT
TH_0608|M.thermoresistible__bu      AGNAAAFGLGSRFFHRVPDRLIEKVMPKPGTGPSERTRERGHYTVETYTT
MSMEG_4632|M.smegmatis_MC2_155      ASNAATMGLGGRFFDKIPSGLLERVLPKPGTGPSEQTRERGHYRVETYTT
MAV_1723|M.avium_104                GTAAATFGLGSRYFRFLPRRLVERIVPKPGTGPSPSARERGYYRIETYTT
MAB_4339c|M.abscessus_ATCC_199      GALTVGFGLGTRVP--LPKFIAQRVLPKPGTGPSERTRERGHYRVETYTT
Mb2977|M.bovis_AF2122/97            GTVAGTIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTT
Rv2953|M.tuberculosis_H37Rv         GTVAGTIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTT
MLBr_00129|M.leprae_Br4923          SVVAGAVGLGNKYFNRLPRRVVERVTPKSGTGPSRKTQARGHYTFETYTT
MMAR_1757|M.marinum_M               GAIAGGIGLGNKYFSRLPQRALERVTPKPGTGPSQKSRERGHYRCETYTT
MUL_2000|M.ulcerans_Agy99           GAIAGGIGLGNKYFSRLPQRALERVTPKPGTGPSQKSRERGHYRCETYTT
                                    .  .  . *. :    :*    ::: ** ****.  :: **:*  *****

Mflv_2628|M.gilvum_PYR-GCK          TSTGARYVARMSQNGDPGYKATAVLLGESGLALALDRDKLSDLRGILTPA
Mvan_3953|M.vanbaalenii_PYR-1       TSTGARYLARMSQQGDPGYKATSVLLGESGLALALDRDKLSDLRGILTPA
TH_0608|M.thermoresistible__bu      TTTGARYVARMSQQGDPGYQATSVLLGESGLALALDRDKLSDLRGVLTPA
MSMEG_4632|M.smegmatis_MC2_155      TTSGARYVATMAQQGDPGYKATAVLLGECGLALATDRDKLSGLHGVLTPA
MAV_1723|M.avium_104                TTSGARYVARMEQRGDPGYKATSVLLGESGLALAFDRDKLPQLYGVLTPA
MAB_4339c|M.abscessus_ATCC_199      TTEGVRYRAIIAQEGDPGYKATAVLLGESGLTLALDRTELPDRLGVLTPA
Mb2977|M.bovis_AF2122/97            TTTGARYRATFAHNVD-AYKSTAVLLAQSGLALALDRDRLAELRGVLTPA
Rv2953|M.tuberculosis_H37Rv         TTTGARYRATFAHNVD-AYKSTAVLLAQSGLALALDRDRLAELRGVLTPA
MLBr_00129|M.leprae_Br4923          TTTGARYMATFAHNVD-AYKSTAGLLAASGLTLALDRDRLSELRGVLTPA
MMAR_1757|M.marinum_M               TTTGARYLATFAHNVD-AYASTAVLLGESGLALALDRDRLSELRGVLTPA
MUL_2000|M.ulcerans_Agy99           TTTGARYLATFAHNVD-AYASTAVLLGESGLALALDRDRLSELRGVLTPA
                                    *: *.** * : :. * .* :*: **. .**:** ** .*.   *:****

Mflv_2628|M.gilvum_PYR-GCK          AAMGDALLARCPGA-DVSLDVSRLN-
Mvan_3953|M.vanbaalenii_PYR-1       AAMGDALLARFPAA-GVSLDVSRLN-
TH_0608|M.thermoresistible__bu      AAMGDVLLTRLPAA-GVTLTVERLA-
MSMEG_4632|M.smegmatis_MC2_155      AAMGDALLTRLPAA-GVVLETTKLD-
MAV_1723|M.avium_104                AAMGDALLDRFPGA-GVSLQVDRLAG
MAB_4339c|M.abscessus_ATCC_199      AAMGDPLLERLRAARGVTVEVERL--
Mb2977|M.bovis_AF2122/97            AAMGDALLARLPGA-GVVMGTTRLS-
Rv2953|M.tuberculosis_H37Rv         AAMGDALLARLPGA-GVVMGTTRLS-
MLBr_00129|M.leprae_Br4923          AAMGEALLTRLPSA-GVVIGTTRLS-
MMAR_1757|M.marinum_M               AAMGDALLARLPQT-GVVVSATRLH-
MUL_2000|M.ulcerans_Agy99           AAMGDALLARLPQT-GVVVSATRLH-
                                    ****: ** *   : .* : . :*