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M. thermoresistible (build 8) TH_0608 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1291433 - 1292689
length: 419

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0608-100% (419)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2476c-1e-17371.29% (418) hypothetical protein Mb2476c
M. gilvum PYR-GCKMflv_2628-0.076.74% (417) saccharopine dehydrogenase
M. tuberculosis H37RvRv2449c-1e-17371.29% (418) hypothetical protein Rv2449c
M. leprae Br4923MLBr_00129-1e-15063.72% (419) hypothetical protein MLBr_00129
M. abscessus ATCC 19977MAB_4339c-1e-15668.43% (415) hypothetical protein MAB_4339c
M. marinum MMMAR_3775-1e-17573.06% (412) hypothetical protein MMAR_3775
M. avium 104MAV_1723-1e-17472.49% (418) saccharopine dehydrogenase
M. smegmatis MC2 155MSMEG_4632-0.076.76% (413) saccharopine dehydrogenase
M. ulcerans Agy99MUL_3722-1e-17472.57% (412) hypothetical protein MUL_3722
M. vanbaalenii PYR-1Mvan_3953-0.077.35% (415) saccharopine dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2628|M.gilvum_PYR-GCK          MDMSE-NDREHDIVLYGATGFVGKLTAQYLAS--AGTGARIALAGRSTDR
Mvan_3953|M.vanbaalenii_PYR-1       MSANEAHDREHDIVVYGATGFVGKLTAQYLAA--AGAGARIALAGRSTDR
TH_0608|M.thermoresistible__bu      MTAAQ---REFDIVLYGATGFVGKLTARYLAS--AGVGARIALAGRSEQK
MSMEG_4632|M.smegmatis_MC2_155      MTQ-----REFDLVLYGATGFAGKLTAQYLAG--AAGDARIALAGRSAEK
Mb2476c|M.bovis_AF2122/97           MTATP---REFDIVLYGATGFVGKLTAEYLAR--AGGDARIALAGRSTQR
Rv2449c|M.tuberculosis_H37Rv        MTATP---REFDIVLYGATGFVGKLTAEYLAR--AGGDARIALAGRSTQR
MAV_1723|M.avium_104                MTATP---REFDIVLYGATGFVGKLTAEYLAG--AAPDKRIALAGRSTEK
MMAR_3775|M.marinum_M               MSETP---REFDIILYGATGFVGKLTAQYLAR--AGGDARIALAGRSTDR
MUL_3722|M.ulcerans_Agy99           MSETP---REFDIILYGATGFVGKLTAQYLAR--AGGDARIALAGRSTDR
MAB_4339c|M.abscessus_ATCC_199      MS------REHDIVLYGATGYVGKLTALYLAGRVEATGARIALAGRSTEK
MLBr_00129|M.leprae_Br4923          MSPDK---REFDIVLYGATGFSGKLTAEHLAL--SESTARIALAGRSSER
                                    *       **.*:::*****: ***** :**        ******** ::

Mflv_2628|M.gilvum_PYR-GCK          LLAVRDSLGEQAKDWPLIVADASQPSTINAMAASTRVVVTTVGPYLRYGL
Mvan_3953|M.vanbaalenii_PYR-1       LLAVRESLGEAAQDWPLLVADASQPSTLNAMAASTRVVITTVGPYLRYGL
TH_0608|M.thermoresistible__bu      LAAVRESLGEAAASWPLLTADADQPATLDELASRTQVVVTTVGPYTKYGM
MSMEG_4632|M.smegmatis_MC2_155      LQAARDSIGGAAADWPLVIADADNPSTLADMAARTRVVVTTVGPYTRYGL
Mb2476c|M.bovis_AF2122/97           VLAVREALGESAQTWPILTADASLPSTLQAMAARAQVVVTTVGPYTRYGL
Rv2449c|M.tuberculosis_H37Rv        VLAVREALGESAQTWPILTADASLPSTLQAMAARAQVVVTTVGPYTRYGL
MAV_1723|M.avium_104                LHAVRDSLGDAAQSWPVLQADASSPATLNEMAARTQVVITTVGPYTRYGL
MMAR_3775|M.marinum_M               LLAVRQTLGEAAQSWPVVSADAGAPATLKEMAARTRVVVTTVGPYMRYGL
MUL_3722|M.ulcerans_Agy99           LLAVRQTLGEAAQSWPVVSADAGAPATLKEMAARTRVVVTTVGPYMRYGL
MAB_4339c|M.abscessus_ATCC_199      LAAVRDACGPAARDWPLIEADTTRPATLAAMAASTQVVLTTVGPYTKYGL
MLBr_00129|M.leprae_Br4923          LRNVRALLGPNAQDWPLIVADASQPSTLEAMAGRAQVVLTTVGPYTRYGL
                                    :  .*   *  *  **:: **:  *:*:  :*. ::**:****** :**:

Mflv_2628|M.gilvum_PYR-GCK          PLVAACAAAGTDYADLTGETLFVRRAIDLHHKQAVDTGARIVHACGFDSI
Mvan_3953|M.vanbaalenii_PYR-1       PLVAACAAAGTDYADLTGETLFVRECIDLYHKQAADTGARIVHACGFDSI
TH_0608|M.thermoresistible__bu      PLVAACAVAGTDYADLTGETMFIRRAIDLYHKQAADNGARIVHSCGFDSI
MSMEG_4632|M.smegmatis_MC2_155      PLVAACAAAGTDYADLTGETMFIRDSIDRYHQQAVDTGARIVHSCGFDSV
Mb2476c|M.bovis_AF2122/97           PLVAACAAAGTDYADLTGEPMFMRNSIDLYHKQAADTGARIVHACGFDSV
Rv2449c|M.tuberculosis_H37Rv        PLVAACAAAGTDYADLTGEPMFMRNSIDLYHKQAADTGARIVHACGFDSV
MAV_1723|M.avium_104                PLVAACAAAGTDYADLTGEAMFVRDSIDSYHKQAADTGARIVHACGFDSV
MMAR_3775|M.marinum_M               PLVAACAAAGTDYADLTGEPPFVRESIDLYHKQAADTGARIVHACGFDSI
MUL_3722|M.ulcerans_Agy99           PLVAACAAAGTDYADLTGEPPFVRESIDLYHKQAADTGARIVHACGFDSI
MAB_4339c|M.abscessus_ATCC_199      PLVAACAEAGTDYADLTGEVNFVRESIDVYGKQAADTGARIVHCCGFDSI
MLBr_00129|M.leprae_Br4923          PLVAACARTGTDYADLTGELMFCRNSIDLHHKQAAATGARIILACGFDSV
                                    ******* :**********  * * .** : :**. .****: .*****:

Mflv_2628|M.gilvum_PYR-GCK          PSDMTVFALYRQAERDGTGQLGDTNFVARSFAG-GVSGGTIASMTELARE
Mvan_3953|M.vanbaalenii_PYR-1       PSDMTVFALYRAAERDRTGELGDTNFVVRSFAG-GVSGGTVASMTELARQ
TH_0608|M.thermoresistible__bu      PSDITVYALYRRAVEDGTGELGDTNLVVRRFAG-GVSGGTAASMLEVMRT
MSMEG_4632|M.smegmatis_MC2_155      PSDLTVFALHRRATADGAGELVDTDLVLRSFAG-GVSGGTAASMIEVLRT
Mb2476c|M.bovis_AF2122/97           PSDLSVYALYHAAREDGAGELTDTNCVVRSFKG-GFSGGTIASMLEVLST
Rv2449c|M.tuberculosis_H37Rv        PSDLSVYALYHAAREDGAGELTDTNCVVRSFKG-GFSGGTIASMLEVLST
MAV_1723|M.avium_104                PSDLSVYALYRAARDDGAGELVDTDLVVRSFSG-GVSGGTVASMLEVLDT
MMAR_3775|M.marinum_M               PSDLTVYALYRAVRDDGAGELGRTDFVVRSFAG-GVSGGTVASMLEILRA
MUL_3722|M.ulcerans_Agy99           PSDLTVYALYRAVRDDGAGELGRTDFVVRSFAG-GVSGGTVASMLEILRA
MAB_4339c|M.abscessus_ATCC_199      PSDLSVYALYRRAQEDGTGELLDTTYVLSKFRG-GVSGGTAASMVEVMEA
MLBr_00129|M.leprae_Br4923          PSDLNVYQLYRRVIEDRTGELCDTDLVLRSFSQRWVSGGSVAAYSEAMLT
                                    ***:.*: *:: .  * :*:*  *  *   *    .***: *:  *    

Mflv_2628|M.gilvum_PYR-GCK          ASLDPEARRLLNDPYTLTPDRGAEPELGPQPDARWRRGREIAPELDGYWV
Mvan_3953|M.vanbaalenii_PYR-1       ASQDPEARRLLNDPYTLTPDRAAEPELGAQPDARWRRGREIAPELDGYWV
TH_0608|M.thermoresistible__bu      ASEDPEARRLMTDPYTLSPDRAAEPELGGQPDIRWRRGGEIAPELEGYWT
MSMEG_4632|M.smegmatis_MC2_155      SSTDPAARAAMTDPYTLSPDRSREPELGDQPDVRWRRGSEIAPELAGYWT
Mb2476c|M.bovis_AF2122/97           ASNDPDARRQLSDPYMLSPDRGAEPELGPQPDLPSRRGRRLAPELAGVWT
Rv2449c|M.tuberculosis_H37Rv        ASNDPDARRQLSDPYMLSPDRGAEPELGPQPDLPSRRGRRLAPELAGVWT
MAV_1723|M.avium_104                ASRDPEARRQLADPYTLSSDRGAEPDVGPQPDLPCRRGRQIAPELAGVWT
MMAR_3775|M.marinum_M               VSADPDLRRQFTDPYTLSTDRAAEPELGPQPDLPWRRGGRIAPELTGLWT
MUL_3722|M.ulcerans_Agy99           VSAAPDLRRQFTDPYTLSTDRAAEPELGPQPDLPWRRGGRIAPELTGLWT
MAB_4339c|M.abscessus_ATCC_199      SAEDPEVRRNAQDPYSLSPDRPAEPEVGRQREFQTLRGESVAPELTGKWL
MLBr_00129|M.leprae_Br4923          TSNDPEALRLVTDPYTLTTDRDAEPDLGPQPDFPRHRGSDLAPELAGFWT
                                     :  *       *** *:.**  **::* * :    **  :**** * * 

Mflv_2628|M.gilvum_PYR-GCK          GAFAMALPNTRVVRRSNALLDYAYGRRFEYAELMSTGRSIGAPVLAAVAT
Mvan_3953|M.vanbaalenii_PYR-1       GAFAMALPNTRVVRRSNALLGYAYGRRFEYAEQMSTGRSVGAPLVAAMAT
TH_0608|M.thermoresistible__bu      GAFVMAVANTRIVRRTNALLDYAYGRRFEYAEQMSLGKSIAAPVAAALAT
MSMEG_4632|M.smegmatis_MC2_155      GAFAMAGPNTRIVRRSNALLDYAYGRRFAYAEQMSCGRSPAAPIAAALVT
Mb2476c|M.bovis_AF2122/97           AGFIMAPTNTRIVRRSNALLDWAYGRRFRYSETMSVGSTVLAPVVSVVGG
Rv2449c|M.tuberculosis_H37Rv        AGFIMAPTNTRIVRRSNALLDWAYGRRFRYSETMSVGSTVLAPVVSVVGG
MAV_1723|M.avium_104                AGFVMAPYNTRIVRRSNALLDWAYGRSLRYSESMSLGSSPLAPVASAVVG
MMAR_3775|M.marinum_M               AGFMMAPTNTRIVRRSNALLDWAYGRRFQYTEHMSLGSSAVAPVASAMIS
MUL_3722|M.ulcerans_Agy99           AGFMMAPTNTRIVRRSNALLDWAYGKRFQYTEHMSLGSSAVAPVASAMIS
MAB_4339c|M.abscessus_ATCC_199      GAFFMGPVNTRIVRRSNALLDWAYGTRMRYREAMSLGSSVVAPVAAAAVT
MLBr_00129|M.leprae_Br4923          GGFVQAQFNTRIVRRSNALQNWSYGRQFRYSETMSLGKSWAAPVASAAVT
                                    ..*  .  ***:***:*** .::**  : * * ** * :  **: :.   

Mflv_2628|M.gilvum_PYR-GCK          AGNAATMQLGSRFLNRVPRAALERVLPKPGTGPNEQTRERGHYTVETYTT
Mvan_3953|M.vanbaalenii_PYR-1       AGNVATMELSSRFLDRVPRGALERILPKVGTGPSEQTRERGHYTVETYTT
TH_0608|M.thermoresistible__bu      AGNAAAFGLGSRFFHRVPDRLIEKVMPKPGTGPSERTRERGHYTVETYTT
MSMEG_4632|M.smegmatis_MC2_155      ASNAATMGLGGRFFDKIPSGLLERVLPKPGTGPSEQTRERGHYRVETYTT
Mb2476c|M.bovis_AF2122/97           GVGNAMFGLASRYIRLLPRGLVKRVVPKPGTGPSAAARERGYYRIETYTT
Rv2449c|M.tuberculosis_H37Rv        GVGNAMFGLASRYIRLLPRGLVKRVVPKPGTGPSAAARERGYYRIETYTT
MAV_1723|M.avium_104                GTAAATFGLGSRYFRFLPRRLVERIVPKPGTGPSPSARERGYYRIETYTT
MMAR_3775|M.marinum_M               GVGNAMTGLGSRYFRLLPQRLVERIAPKPGTGPSAATRERGYYRIETYTT
MUL_3722|M.ulcerans_Agy99           GVGNAMTGLGSRYFRLLPQRLVERIAPKPGTGPSAATRERGYYRIETYTT
MAB_4339c|M.abscessus_ATCC_199      GALTVGFGLGTRVP--LPKFIAQRVLPKPGTGPSERTRERGHYRVETYTT
MLBr_00129|M.leprae_Br4923          SVVAGAVGLGNKYFNRLPRRVVERVTPKSGTGPSRKTQARGHYTFETYTT
                                    .       *. :    :*    ::: ** ****.  :: **:* .*****

Mflv_2628|M.gilvum_PYR-GCK          TSTGARYVARMSQNGDPGYKATAVLLGESGLALALDRDKLSDLRGILTPA
Mvan_3953|M.vanbaalenii_PYR-1       TSTGARYLARMSQQGDPGYKATSVLLGESGLALALDRDKLSDLRGILTPA
TH_0608|M.thermoresistible__bu      TTTGARYVARMSQQGDPGYQATSVLLGESGLALALDRDKLSDLRGVLTPA
MSMEG_4632|M.smegmatis_MC2_155      TTSGARYVATMAQQGDPGYKATAVLLGECGLALATDRDKLSGLHGVLTPA
Mb2476c|M.bovis_AF2122/97           TTTGARYLARMAQDGDPGYKATSVLLGECGLALALDRDKLSDMRGVLTPA
Rv2449c|M.tuberculosis_H37Rv        TTTGARYLARMAQDGDPGYKATSVLLGECGLALALDRDKLSDMRGVLTPA
MAV_1723|M.avium_104                TTSGARYVARMEQRGDPGYKATSVLLGESGLALAFDRDKLPQLYGVLTPA
MMAR_3775|M.marinum_M               TTSGDRYVARMEQGGDPGYKATSVLLGECGLALAFDRDQLSGLHGVLTPA
MUL_3722|M.ulcerans_Agy99           TTSGDRYVARMEQDGDPGYKATSVLLGECGLALAFDRDQLSGLHGVLTPA
MAB_4339c|M.abscessus_ATCC_199      TTEGVRYRAIIAQEGDPGYKATAVLLGESGLTLALDRTELPDRLGVLTPA
MLBr_00129|M.leprae_Br4923          TTTGARYMATFAHNVD-AYKSTAGLLAASGLTLALDRDRLSELRGVLTPA
                                    *: * ** * : :  * .*::*: **. .**:** ** .*.   *:****

Mflv_2628|M.gilvum_PYR-GCK          AAMGDALLARCPGA-DVSLDVSRLN-
Mvan_3953|M.vanbaalenii_PYR-1       AAMGDALLARFPAA-GVSLDVSRLN-
TH_0608|M.thermoresistible__bu      AAMGDVLLTRLPAA-GVTLTVERLA-
MSMEG_4632|M.smegmatis_MC2_155      AAMGDALLTRLPAA-GVVLETTKLD-
Mb2476c|M.bovis_AF2122/97           AAMGDALLERLPAA-GVSLQTTRLAS
Rv2449c|M.tuberculosis_H37Rv        AAMGDALLERLPAA-GVSLQTTRLAS
MAV_1723|M.avium_104                AAMGDALLDRFPGA-GVSLQVDRLAG
MMAR_3775|M.marinum_M               AAMGDALLARLPAA-GVALATERLT-
MUL_3722|M.ulcerans_Agy99           AAMGDALLARLPAA-GVALATERLT-
MAB_4339c|M.abscessus_ATCC_199      AAMGDPLLERLRAARGVTVEVERL--
MLBr_00129|M.leprae_Br4923          AAMGEALLTRLPSA-GVVIGTTRLS-
                                    ****: ** *  .* .* : . :*