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SDFDNITTADDVFKLAAQRTGLSEIDSDSWREGLALIVDEVNTSPVFTPFGRQRVLDDATNALGRRLQVH AYIQDHPEVLDAPVERPLIVLGMPRTGTTVISYLLDQDPARRSLLHWQCVHPIPPASTETLRTDPRCLAL LDEQRKILDAVTRAKMPLPHWEDADGPTEDMFIHNQDFKGLSWDSFLPTDRYARWLFDEADMSSTYEYQK RYLQVLQSTAPGSWSLKMPSHSVHIEALLKVFPDARLIWAHRDPYKATGSLCNLWRLPQSLVMNTELLDQ TEMGRLAMWQMRYHVDRPLRARERIGDERFFHMYYHEMMRDPMDVMRRIYEWADEPLTAETEARMRNWLA HHPQDRFALNAYRLDEYGLTVEALQPIFAEYLDTFDIELEGRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4174 | - | - | 100% (394) | hypothetical protein MAV_4174 |
| M. avium 104 | MAV_3100 | - | 3e-49 | 31.55% (374) | sulfotransferase |
| M. avium 104 | MAV_5269 | - | 3e-44 | 30.26% (380) | hypothetical protein MAV_5269 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 7e-32 | 28.39% (384) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_3480 | - | 1e-175 | 72.63% (391) | hypothetical protein Mflv_3480 |
| M. tuberculosis H37Rv | Rv3529c | - | 7e-32 | 28.39% (384) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 3e-42 | 28.19% (376) | putative sulfotransferase |
| M. marinum M | MMAR_0220 | - | 3e-40 | 28.12% (377) | hypothetical protein MMAR_0220 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 6e-32 | 27.63% (380) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 4e-32 | 26.99% (389) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4091 | - | 4e-33 | 28.53% (389) | hypothetical protein MUL_4091 |
| M. vanbaalenii PYR-1 | Mvan_2324 | - | 9e-57 | 33.60% (378) | hypothetical protein Mvan_2324 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3559c|M.bovis_AF2122/97 ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
Rv3529c|M.tuberculosis_H37Rv ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
MUL_4091|M.ulcerans_Agy99 -------------------MADRTDVGTVDELHASATKLVGLDDFGSD--
MSMEG_5930|M.smegmatis_MC2_155 -------------------------MGTVEDLHASATKATGLDDFGTD--
TH_0375|M.thermoresistible__bu -------------------MTPRTDVGTVEDLHASAVKACGLEDFGSD--
MAB_3968|M.abscessus_ATCC_1997 MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQWLRSAARRATGLEWV
MAV_4174|M.avium_104 -------------------MSDFDNITTADDVFKLAAQRTGLSEIDSD--
Mflv_3480|M.gilvum_PYR-GCK -------------------MGEFDDIATPDDVLRLAAQRTGLSDVDGD--
Mvan_2324|M.vanbaalenii_PYR-1 -------------------------MASSDDLLRAARGSSGLDDFGDD--
MMAR_0220|M.marinum_M -------------------MSMPQDRFKPERLIATACEEAGSDDFGADG-
: . . :
Mb3559c|M.bovis_AF2122/97 -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
Rv3529c|M.tuberculosis_H37Rv -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
MUL_4091|M.ulcerans_Agy99 -QDTYREALEVLLDSYRREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQ
MSMEG_5930|M.smegmatis_MC2_155 -DDNYREALGVLLESYQRDAHLTELGSKMSRFFLRNALVARLLSEASWKA
TH_0375|M.thermoresistible__bu -DDNYKEALAVLLDSYQREADLTELGSKMSRFFLRNALVARLVSEAAWKQ
MAB_3968|M.abscessus_ATCC_1997 ADAYLDDALEVLAASLRNDAKLSFLGRKMVQVRLVGMLSTRLRLRELIRK
MAV_4174|M.avium_104 ---SWREGLALIVDEVNTSPVFTPFGRQRVLDDATNALGRRLQVHAYIQD
Mflv_3480|M.gilvum_PYR-GCK ---SWREGLAIVLDEVNNCPAFTETGRARIIDDATKALARRLQVHDYIQQ
Mvan_2324|M.vanbaalenii_PYR-1 ---AFREGLDILVGALDREARLNARGEAFMYPRIVGHLRQRLQVEDWYRR
MMAR_0220|M.marinum_M ----WQDGLQRVTDALIHEARLSAIGVEIAHLDLMRALRNRLGVIAWRRQ
:.* : . :. * * ** :
Mb3559c|M.bovis_AF2122/97 YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
Rv3529c|M.tuberculosis_H37Rv YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
MUL_4091|M.ulcerans_Agy99 YPQYAEVPIQRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPR
MSMEG_5930|M.smegmatis_MC2_155 NPQYADVEIERPIFVTGLPRTGTTVLHRLLTADPAHQGLEMWLAEFPQPR
TH_0375|M.thermoresistible__bu YPQHADVVIERPIFVTGLPRTGTTALHRLLAADPAHQGLELWLAEFPQPR
MAB_3968|M.abscessus_ATCC_1997 NPGIAQLPVEPPIVIVGLQRTGTTLLHRLLAADPSAGSMSSWEGASPLPH
MAV_4174|M.avium_104 HPEVLDAPVERPLIVLGMPRTGTTVISYLLDQDPARRSLLHWQCVHPIPP
Mflv_3480|M.gilvum_PYR-GCK HPEVLEVPVERPLVTLGMPRTGTTVISYLLAADPKRRSLLHWECLNPVPP
Mvan_2324|M.vanbaalenii_PYR-1 HPEIDDERVDAPLFGLGLPRTGSTALSFLLAQDPGIRYLHSWEAARPCPP
MMAR_0220|M.marinum_M HPEIATKAIDQPIVIVGQPRTGTTILYDLLAQDPDLRAPLTWEVDAPCPV
* :. *:. * ***:* : ** ** * * *
Mb3559c|M.bovis_AF2122/97 PPRETWESNPLYRQLDAQFTQ--HHAENPGYTGLHFMAAYELEECWQLLR
Rv3529c|M.tuberculosis_H37Rv PPRETWESNPLYRQLDAQFTQ--HHAENPGYTGLHFMAAYELEECWQLLR
MUL_4091|M.ulcerans_Agy99 PPRETWETNPFYRQLDAQLTQ--HRKDNTGYTGLHFMAAYELEECWQLLR
MSMEG_5930|M.smegmatis_MC2_155 PPRETWPDNPVYQQLAASFSQ--HHQENPDYTGLHFMTADEVEECWQLLR
TH_0375|M.thermoresistible__bu PPRETWPDNPIYRQLEAQFTK--AHQENPDYTGLHFMTAGEVEECWQLLR
MAB_3968|M.abscessus_ATCC_1997 PEQPSGAPDLRIAQAAKDERS--LRYLAPQFFAIHSVEAEAPEEDVLLLD
MAV_4174|M.avium_104 ASTETLRTDPRCLALLDEQRKILDAVTRAKMPLPHWEDADGPTEDMFIHN
Mflv_3480|M.gilvum_PYR-GCK ATTDTLRSDPRCVALLGEQKLILDMVKAAKMPIPHWEDADGPTECMFIHN
Mvan_2324|M.vanbaalenii_PYR-1 PSTVAG-DDPRIPPGVTEVP----AGSRHHVPS----DPDGPAECLDLMA
MMAR_0220|M.marinum_M PAPETYLSDPRIAQTQASIELS--EQIIPGFLSFHPMGAQVGQECVRITA
. : : . . * :
Mb3559c|M.bovis_AF2122/97 QSLHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEKRW
Rv3529c|M.tuberculosis_H37Rv QSLHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEKRW
MUL_4091|M.ulcerans_Agy99 QSLHSVSYETLAHLPSYAQWLA-KQDWTPSYQRHRKNLQLIGLNDAEKRW
MSMEG_5930|M.smegmatis_MC2_155 QSLHSVSYETLAHLPTYANWLA-QQDWTRPYQRHRRNLQLIGLNDAEKRW
TH_0375|M.thermoresistible__bu QSVHSVSYETLAHVPSYARWLA-RQDWTKPYQRHRRNLQLIGLNDVEKRW
MAB_3968|M.abscessus_ATCC_1997 FALHSQMPEVMFHVPGYAKWLA-DQDMTPAYELHRLLLQVLQWQQPRGRW
MAV_4174|M.avium_104 QDFKGLSWDSFLPTDRYARWLFDEADMSSTYEYQKRYLQVLQSTAPG-SW
Mflv_3480|M.gilvum_PYR-GCK QDFKGLSWDAFMATPRYAEWLLNDADMISAYEYQKRYLQVLQSKAPG-TW
Mvan_2324|M.vanbaalenii_PYR-1 LDFTSQIFQAFAHIPSYSQWLVERADFTSTYTYQRRVLKLLQWGQPTRPW
MMAR_0220|M.marinum_M SEFTSMIYSVQYRLPSYYRWLLYEADHRGAYRFHRIFLQHLQSGVAG-QW
. . . * ** * .* :: *: : *
Mb3559c|M.bovis_AF2122/97 VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLA--QHTTEGW
Rv3529c|M.tuberculosis_H37Rv VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLA--QHTTEGW
MUL_4091|M.ulcerans_Agy99 VLKNPSHLFALDALMASYPDALVIQTHRPVETIMASMCSLA--QHTSEGW
MSMEG_5930|M.smegmatis_MC2_155 VLKNPSHLFALDALFATYPDALVIQCHRPAETIMASMCSLS--AHTTAGW
TH_0375|M.thermoresistible__bu VLKNPSHLFALDALFATYPDALVVQCHRPAETIMASMCSLS--QHTTAGW
MAB_3968|M.abscessus_ATCC_1997 VLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTASSSSML--AHYQALF
MAV_4174|M.avium_104 SLKMPSHSVHIEALLKVFPDARLIWAHRDPYKATGSLCNLWRLPQSLVMN
Mflv_3480|M.gilvum_PYR-GCK SLKMPSHSVHIEALLTVFPDARLIWAHRDPYKATGSLGNLLTLPKSMVLN
Mvan_2324|M.vanbaalenii_PYR-1 RLKSPAHVLSLDCLDAVFPDARFVMTHRDPTDVLLSVADVY--ADIVGGF
MMAR_0220|M.marinum_M LLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALT--HHLRRMA
** *:* :: * :*.* .: ** * : .
Mb3559c|M.bovis_AF2122/97 STKFVGAQIGADAMDTWSRGLERFNAARA--KYDSAQFYDVDYHDLIADP
Rv3529c|M.tuberculosis_H37Rv STKFVGAQIGADAMDTWSRGLERFNAARA--KYDSAQFYDVDYHDLIADP
MUL_4091|M.ulcerans_Agy99 STNFVGAQIGADAMETWSRGLQPFDSART--NYDPAQFYDVDYRDLIADP
MSMEG_5930|M.smegmatis_MC2_155 SNTFVGAQIGADAMDTWARGLEAFTAERA--KHDPAQFLDVDYDDFVADP
TH_0375|M.thermoresistible__bu SNTFVGAQIGADAMETWTRGLRLFNEARA--NYDPAQFHDVEYADFVKDP
MAB_3968|M.abscessus_ATCC_1997 SDRVDHHELARYWLGKNAQIIDRAIAVRA--EHP-AAFVDINYTELLDDP
MAV_4174|M.avium_104 TELLDQTEMGRLAMWQMRYHVDRPLRARE--RIGDERFFHMYYHEMMRDP
Mflv_3480|M.gilvum_PYR-GCK PEAMTTTEWGANLKDQMRQHVERPLRTRE--RIGDDRFFDMYYHEMMRDP
Mvan_2324|M.vanbaalenii_PYR-1 SDHVDRRYLGELNTYQWSVGMGRAVAFRE--DGADHRFFDIDFRTMAQDP
MMAR_0220|M.marinum_M SDESSIAECAAQCYEEIVVGLDREMALRAGGALPAGQVIDVLYTDFINDP
. . : * . .: : : **
Mb3559c|M.bovis_AF2122/97 LGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTV
Rv3529c|M.tuberculosis_H37Rv LGTVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTV
MUL_4091|M.ulcerans_Agy99 MGTVADIYRHFGLTLTDEARAAMAKIHAESQTGERAPKHRYSLADYGLTA
MSMEG_5930|M.smegmatis_MC2_155 LATVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPKHTYSLADYGLTS
TH_0375|M.thermoresistible__bu IGTVEGIYRHFGLEFTDAARDAMTRLHTESQRGPRAPRHSYSLADYGLTA
MAB_3968|M.abscessus_ATCC_1997 IAAVQRIYHAADRRLSDDALTAMRVSLQQNRQHKHG-EHRYSLAQFGLTI
MAV_4174|M.avium_104 MDVMRRIYEWADEPLTAETEARMRNWLAHHPQ-DRFALNAYRLDEYGLTV
Mflv_3480|M.gilvum_PYR-GCK MDVMRRLYDWAGDPLTPDTETRMQSWLAEHPQ-GLLGHSSYSLDQYGLSV
Mvan_2324|M.vanbaalenii_PYR-1 VGEVRALYAWLGDPVTVEFESGMRGWWAHNAQ-NREAKPTADPGAFGLDP
MMAR_0220|M.marinum_M WSTIRGVYRKLGRELAPETEQRMRDFLRAHPG--DGGRGRYTWSDTGLDA
: :* . : : **
Mb3559c|M.bovis_AF2122/97 EMVKERFAGL-----------------
Rv3529c|M.tuberculosis_H37Rv EMVKERFAGL-----------------
MUL_4091|M.ulcerans_Agy99 EAVKERFAGF-----------------
MSMEG_5930|M.smegmatis_MC2_155 EAVKERFTGL-----------------
TH_0375|M.thermoresistible__bu ESVRDAFSGL-----------------
MAB_3968|M.abscessus_ATCC_1997 AEVDAAYRRYIDHFAIQTERGGVRGDR
MAV_4174|M.avium_104 EALQPIFAEYLDTFDIELEGRP-----
Mflv_3480|M.gilvum_PYR-GCK EELTPVFAEYLGTFDIELEDA------
Mvan_2324|M.vanbaalenii_PYR-1 GRIRPLFADYVAHARRWIGPRDAPEER
MMAR_0220|M.marinum_M SVVRDRVRPYQDRYGVPTEQLR-----
: