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SSGLLSYASYLPRYRLSGQDIGVRHGNRVVASYDEDSTTMAVAAASSALMHSAVSPRALYFATSSPAYAD KTNATAIHAALGLPADMPAADMCGTARSAFAALTLAASSGGLVVAADVRVGRPGSADEKLGGDGAAALIF GEGDVIAEYLASRSLTAEFLDRWRDPTSRTGQQWEERFGAQHYTALIRDAAREALDAAGIADPDHVVVAC PNSGVVKRAATLVKGQKTVATSVGFGGSADALIALCGTLDVAEAGDTILVLSATDGCDAMVLRATSRLPR ARQPRPLNDQRAEGTPVEYVTYLAWRGLVTMEPPRRPEPERPAAPPASRARLWKFGMTGARCRACGFMHL PPVRVCRSCNAIDEMDPQSAAGLRGTVVTYTVDRLAYSPSPPMVQAVVDVDGGGRCTLEVADARVEDLRV GTRVRFSFRRLFTASDVHNYFWKVVQDDAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5080 | - | - | 100% (451) | hypothetical protein MAV_5080 |
| M. avium 104 | MAV_2556 | - | 2e-09 | 26.72% (464) | hypothetical protein MAV_2556 |
| M. avium 104 | MAV_5258 | - | 1e-08 | 31.85% (135) | hypothetical protein MAV_5258 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2504 | - | 5e-09 | 24.88% (426) | hypothetical protein Mflv_2504 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3213 | pksG | 7e-06 | 24.15% (236) | hydroxymethylglutaryl-coenzyme A synthase, PksG |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 0.0001 | 26.98% (126) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3473 | - | 1e-172 | 67.11% (450) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5080|M.avium_104 -------------------MSSGLLSYASYLPRYRLSGQDIGVRHGNRVV
TH_3473|M.thermoresistible__bu --------------------VTGLLGYATYVPAYRL---------GKRVV
Mflv_2504|M.gilvum_PYR-GCK --------------------MPYVTSIGTYLPCWGT---------PLQRV
MMAR_3213|M.marinum_M ------------------MVSIGIHDLSIATAHYVLD------HATLAEH
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
.
MAV_5080|M.avium_104 ASYDEDSTTMAVAAASSALMH---------SAVSPRALYFATSSPAYADK
TH_3473|M.thermoresistible__bu AAYDEDSTTMAVAAAAELLRG---------PGAPPESVYFATSSPAYADK
Mflv_2504|M.gilvum_PYR-GCK AGDDEDAVTMAVEAGRAALTN---------GGAVER-VVFVSRDLPLLES
MMAR_3213|M.marinum_M HGVDVNKYLIGLGQQQMSIVA---------PDEDIVTLAAAAADPIIKRH
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
. * . :. : .
MAV_5080|M.avium_104 T---NATAIHAALGLPADMPAADMCGTARSAFAALTLAASSGG-LVVAAD
TH_3473|M.thermoresistible__bu T---NATAVHAALGLDAGVFAADMCGTGRSAFAAIRSAARSGG-LAVFAD
Mflv_2504|M.gilvum_PYR-GCK S---NAAVLLAGLGLDPELEVDERLGGAPATVDAVS-SARPRT-LIIGAD
MMAR_3213|M.marinum_M G---SQKIRTIVIGTETGVDQSKSAGIWVSSLLGLPSSARVLE-VKQACY
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
. :* : . . . . :: : .
MAV_5080|M.avium_104 VRVGRPGSADEKLGGDGAAALIFGEGDVIAEYLASRSLTAEFLDRWRDPT
TH_3473|M.thermoresistible__bu VRIGRPGSADERLGGDAAAALLFGTGEPIAEVLATASRTAEFLDRWRIPT
Mflv_2504|M.gilvum_PYR-GCK LAPAG-----------AAAILTAEQG---LQVRTAARVARSLPVRTRNAT
MMAR_3213|M.marinum_M GATGA-----------LQLALALVHRDPTQQVLVIAADVARYDLDS--PG
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
. .
MAV_5080|M.avium_104 SRTGQQWEERFGAQHYTALIRDAAREALDAAGIADP--------DHVVVA
TH_3473|M.thermoresistible__bu HPTGHQWEERFGYERYAPLIRATVEQALDAVGLADV--------DHVALA
Mflv_2504|M.gilvum_PYR-GCK GDVHDYGDPRLLHER--GLIASLAAAWLDTP---------------VAIA
MMAR_3213|M.marinum_M EPTQGAAAAAMLVSADPALLRLEEPTGIYTA-------------DIMDFW
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYPGLDIAGMGEGGVSVLEGALGLRPTWINGGMDTF
. . * : :
MAV_5080|M.avium_104 CPNSGVVKRAATLVKGQK-TVATS-VGFGGSADALIALCGTLDVAEAGDT
TH_3473|M.thermoresistible__bu CPNTAVLKRAAALVKGQK-SVVTSPVGFGGSADAGLALCAVLDTADPGDT
Mflv_2504|M.gilvum_PYR-GCK GVDH---DRAAELCLGDP-PALPT----TGASASLFALAGLAEQGRTG--
MMAR_3213|M.marinum_M RPNY----RSTALVDGKA-SVTAYMEAASGAWKDYTERGGRAFG------
MSMEG_4814|M.smegmatis_MC2_155 GPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKMSPPMSARTN
. : * . .:
MAV_5080|M.avium_104 ILVLSATDGCDAMVLRATSRLPRARQPRP-------LNDQRAEGTPVEYV
TH_3473|M.thermoresistible__bu VLMVSAADGCDAMVFRTTAALADRRQRRP-------LAEQRSGGRQVPQL
Mflv_2504|M.gilvum_PYR-GCK --PLVAVEQAILSGISVSGGHAQTHRREP-------GPQQEAERR-----
MMAR_3213|M.marinum_M ----EFAAFCYHQPFTKMAYKAHKQLAAE-------AGEDASGAA-----
MSMEG_4814|M.smegmatis_MC2_155 SWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQRANAALNPTA
. : . : :: :
MAV_5080|M.avium_104 TYLAWRGLVTMEPPRRPEPERPAAPPASRARLWKFGMTGARCRACGFMHL
TH_3473|M.thermoresistible__bu TYLSWRGLVEPEPPRRPDPDRPAAPPAARAAGWKFGFTGSRCSACGFTHL
Mflv_2504|M.gilvum_PYR-GCK --FSAGGDIPIS-----------LAAYERAFEAKVRWEAGQFAGSDQLDF
MMAR_3213|M.marinum_M VQAAVGNTVEYN----------RRIGNSYTASLYLALAALLDQADDLSDQ
MSMEG_4814|M.smegmatis_MC2_155 IYREPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAVDAARDLPRP
. . .
MAV_5080|M.avium_104 PPVRVCRSCNAIDEMDPQSAAGLRGTVVTYTVDRLAYS-PSPPMVQAVVD
TH_3473|M.thermoresistible__bu PPARVCRSCGARDAAVAVPAGGLTGTIATYTVDHLAYS-PSPPMIQAAVD
Mflv_2504|M.gilvum_PYR-GCK PPRYRVGADGALATHYELVPLPRTGTVYTETTVNIPVPGLHTPYSLVIVE
MMAR_3213|M.marinum_M PIAMLSYGSGCVAELFA-------GTVTPGYQQHLRTD-QHRAALETRIP
MSMEG_4814|M.smegmatis_MC2_155 PIRFEAVGTQIIERLDWDQTTLTHEPQVLGQSAHMWSRTSLRPSDVDVAE
* . . .: .
MAV_5080|M.avium_104 VDGGG-RCTLEVADAR--------------VEDLRVGTRVRFSFR-----
TH_3473|M.thermoresistible__bu VDGGG-RCTLEVADAD--------------PDQLAVGARVGFAFR-----
Mflv_2504|M.gilvum_PYR-GCK LDGVGVRALVKVTGAA--------------PGSVDIGDRGRLALR-----
MMAR_3213|M.marinum_M LSYEHYRRLHNLTLPT--------------NGNHHS---LPVETS-----
MSMEG_4814|M.smegmatis_MC2_155 LYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIPLNTHGGQLS
: . . .
MAV_5080|M.avium_104 --RLFTASDVHNY--FWKVVQDDAE-------------------------
TH_3473|M.thermoresistible__bu --RLFTAGDVHDY--FWKAVLIDGQ-------------------------
Mflv_2504|M.gilvum_PYR-GCK --RVAVRSGVPDYGYAFEPVRAGAES------------------------
MMAR_3213|M.marinum_M --RPFRLTAISEHKRMYGAV------------------------------
MSMEG_4814|M.smegmatis_MC2_155 HGRTHGMGLIHEAVTQLRGEAGERQVEDARVAVASSGGLTPSGVLLLRRD
* : :
MAV_5080|M.avium_104 -
TH_3473|M.thermoresistible__bu -
Mflv_2504|M.gilvum_PYR-GCK -
MMAR_3213|M.marinum_M -
MSMEG_4814|M.smegmatis_MC2_155 D