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MTQVLSIGTYLPPWTVRDRRVKGPDEDALTMAVAAGRAADPEATAQRVALVSRDFPLLEGGNGAVLLAAL SLPADTPVAEVLGGAPAVLDQICSAGEGTLVIAADDNDLAVGAGAVLTGDGGASVTPLARQTRSLPLTAR GADGARHSYVDPRLQREVGVRSTLARLGLAPNSAVAAVAGVPVAQVGGDFDTSHAVGIPTVSATAIIRLL ADAIEAGAQGLLIAVEQSSVSAADLAQGGAKPRVARDEFPARELPKARVADGVGIPISMPAYARAFEPKI RWEAAVFEESPGIDAAPQFPPRLRVDNAGRLATEYRLESLPRTGTVYTHTTVRIPVPDLPSPYSLAVVQL DDSPVRVLLKVTGVPAGEATIGQPGSVVLRRIATRTGIPDYGYAFWPGRTLEGAVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2556 | - | - | 100% (406) | hypothetical protein MAV_2556 |
| M. avium 104 | MAV_1816 | - | 0.0 | 82.29% (401) | hypothetical protein MAV_1816 |
| M. avium 104 | MAV_5080 | - | 2e-09 | 26.72% (464) | hypothetical protein MAV_5080 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2504 | - | 3e-86 | 48.89% (407) | hypothetical protein Mflv_2504 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6041 | - | 6e-06 | 27.52% (218) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4155 | - | 1e-164 | 74.44% (399) | PUTATIVE hypothetical protein MAV_1816 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4154 | - | 7e-89 | 49.87% (399) | hypothetical protein Mvan_4154 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2504|M.gilvum_PYR-GCK ---------MPYVTSIGTYLPCWGTPLQRVAGDDED--------------
Mvan_4154|M.vanbaalenii_PYR-1 ---------MPYVASVGTYLPCWGTSLHRVAGDDED--------------
MAV_2556|M.avium_104 ---------MTQVLSIGTYLPPWTVRDRRVKGPDED--------------
TH_4155|M.thermoresistible__bu ---------MTHIVSIGTYLPPWTSGKRRVKGPDED--------------
MSMEG_6041|M.smegmatis_MC2_155 MSLLSAGAGTSEEFAARDMVRSWAAASGAVAAVRESETDPGAWRAAYQGF
. : : * * . *.
Mflv_2504|M.gilvum_PYR-GCK ---------AVTMAVEAGRAALTNGGAVERVVFVSRDLPLLESSNAAVLL
Mvan_4154|M.vanbaalenii_PYR-1 ---------AVTMAVEAGRAALTAGGAVERVVLVSRDLPLLESSNAAVLL
MAV_2556|M.avium_104 ---------ALTMAVAAGRAADP-EATAQRVALVSRDFPLLEGGNGAVLL
TH_4155|M.thermoresistible__bu ---------ALTMAVAAGRAADP-GAQARAVVLVTRNFPLVEGGNGAVLV
MSMEG_6041|M.smegmatis_MC2_155 AELGIFGVAVPDELGGAGSTVADLAAMIDEAAAALVPGPVVTTALATLLV
. ** :. . .. . *:: . .::*:
Mflv_2504|M.gilvum_PYR-GCK AGLGLDPELEVDERLGGAPATVDAVSSARPRT----LIIGAD-----LAP
Mvan_4154|M.vanbaalenii_PYR-1 AGLGLDPELEVDERLGGAPATVDAVSSARPRT----LIIGAD-----LAP
MAV_2556|M.avium_104 AALSLPADTPVAEVLGGAPAVLDQICSAGEGT----LVIAADDN---DLA
TH_4155|M.thermoresistible__bu AALGLPADTPVSEVLGGAPAVLDQLVSAAPGT----LVIGADDN---DAA
MSMEG_6041|M.smegmatis_MC2_155 TDTGLLEALMSGERTAGVALSADVTVVDGRASGTVEFVLGADAAGVLLLP
: .* * .*.. * : :::.** .
Mflv_2504|M.gilvum_PYR-GCK AGAAAILTAE--QGLQVRTAARVARSLPVRTRNATGD--------VHDYG
Mvan_4154|M.vanbaalenii_PYR-1 AGAAAILTAE--NGLQVRTAARVARSLPVRTRKATGD--------VHDYG
MAV_2556|M.avium_104 VGAGAVLTGD--GGASVTPLARQTRSLPLTARGADGA--------RHSYV
TH_4155|M.thermoresistible__bu AGAAAALTGD--RGAELVVRARQTRSLPLVARSDDGS--------RHTYP
MSMEG_6041|M.smegmatis_MC2_155 AGDDVLLLDAGADGVSVEPLTATDFSIPLARVELDNAPAEVLPVSRQRFS
.* . * * .: : *:*: . : :
Mflv_2504|M.gilvum_PYR-GCK DPRLLHERGLIASLAAAWLD------------------------------
Mvan_4154|M.vanbaalenii_PYR-1 DPRLLHERGLIASLAAAWLD------------------------------
MAV_2556|M.avium_104 DPRLQREVGVRSTLARLGLAPN----------------------------
TH_4155|M.thermoresistible__bu DPRLQREVGVRATLDRLDLR------------------------------
MSMEG_6041|M.smegmatis_MC2_155 DLAATLLAAEAAGLARWTLNTATEYAKVREQFGKPIGSFQAIKHMCAEML
* . : * *
Mflv_2504|M.gilvum_PYR-GCK ---TPVAIAGVD-HDRAAELCLGDPPALPTTGASASLFALAGLAEQ----
Mvan_4154|M.vanbaalenii_PYR-1 ---TPVAVAGVD-RQRAVELCLPDPPAVPTSGASASLFALAAMAEQ----
MAV_2556|M.avium_104 --SAVAAVAGVPVAQVGGDFDTSHAVGIPTVSATAIIRLLADAIEA----
TH_4155|M.thermoresistible__bu --GRVAAAAGVPAAQLGKAVDTSGAVEDRTVSASGLIRALAEAIEG----
MSMEG_6041|M.smegmatis_MC2_155 LRSEQIAVAAADAAKAVAESDGSDSATQLSIAAAVAVATGIDAAKANAKD
* *.. . . : .*: : :
Mflv_2504|M.gilvum_PYR-GCK -------------------------------------------GRTGPLV
Mvan_4154|M.vanbaalenii_PYR-1 -------------------------------------------GRTGPLV
MAV_2556|M.avium_104 -------------------------------------------GAQGLLI
TH_4155|M.thermoresistible__bu -------------------------------------------KGSGLVI
MSMEG_6041|M.smegmatis_MC2_155 CIQVLGGIGITWEHDAHLYLRRAYGIAHFLGGSRRWVRRVAALTRQGARR
*
Mflv_2504|M.gilvum_PYR-GCK AVEQAILSGISVSGG--HAQTHRREPGPQQEAERRFSAGGDIPISLAAYE
Mvan_4154|M.vanbaalenii_PYR-1 AVEQAILSGISVSGG--SAQICRREPPSRALPDGTFIADAEIPISLAAYE
MAV_2556|M.avium_104 AVEQSSVSAADLAQGGAKPRVARDEFPARELPKARVADGVGIPISMPAYA
TH_4155|M.thermoresistible__bu GVEQATISVADLAPG--EVTVTRDEVEPRELPRFTYAEGNGIPISMPAYN
MSMEG_6041|M.smegmatis_MC2_155 DIDIDLESVADLRPEISAAVAEVAALPEEKRQVALAESGLLAPHWPKPYG
:: * .: . . * .*
Mflv_2504|M.gilvum_PYR-GCK RAFEAKVR---------------------WEAGQFAGSDQLD----FPPR
Mvan_4154|M.vanbaalenii_PYR-1 RAFEAKVR---------------------WEAGRFDESGELD----FPPR
MAV_2556|M.avium_104 RAFEPKIR---------------------WEAAVFEESPGIDAAPQFPPR
TH_4155|M.thermoresistible__bu RAFEPKIR---------------------WEAAVFDERPGIDGAPQFPPR
MSMEG_6041|M.smegmatis_MC2_155 RNASPAEQLLIDQELAAAEVERPDLVIGWWAVPTILEHGSPEQIEQFVPA
* .. : * . : : * *
Mflv_2504|M.gilvum_PYR-GCK YRVG-----------ADGALATHYELVPLPRTG-----------------
Mvan_4154|M.vanbaalenii_PYR-1 YRVG-----------DDGALATDYELVPLPRTG-----------------
MAV_2556|M.avium_104 LRVD-----------NAGRLATEYRLESLPRTG-----------------
TH_4155|M.thermoresistible__bu LRVD-----------DGGTLATEYRLEPLPRTG-----------------
MSMEG_6041|M.smegmatis_MC2_155 TLRGDLFWCQLFSEPGAGSDLAALRTKAVRAEGPNGEPGWKLTGQKVWTS
. * : . .: *
Mflv_2504|M.gilvum_PYR-GCK -TVYTETTVNIPVPGLHTP------YSLVIVELDGVGVRALVKVTG----
Mvan_4154|M.vanbaalenii_PYR-1 -TVYTETTVHIPVPGLRTP------YTLVIVELDGVAVRALVKVTG----
MAV_2556|M.avium_104 -TVYTHTTVRIPVPDLPSP------YSLAVVQLDDSPVRVLLKVTG----
TH_4155|M.thermoresistible__bu -TVYTHTTIRIPVPDLPSP------YSLAVVQLDGSPVRVLLKVTG----
MSMEG_6041|M.smegmatis_MC2_155 AAQNAHWGVCLARTDPDAPKHKGITYFLVDMKTPGIVIRPLREITGDELF
: :. : :. .. :* * *. :: . :* * ::**
Mflv_2504|M.gilvum_PYR-GCK -----------------------------------AAPGSVDIGDRGRLA
Mvan_4154|M.vanbaalenii_PYR-1 -----------------------------------AQPGTVDIGHRGRLV
MAV_2556|M.avium_104 -----------------------------------VPAGEATIGQPGSVV
TH_4155|M.thermoresistible__bu -----------------------------------VPAGETTVGQPGAVV
MSMEG_6041|M.smegmatis_MC2_155 NEVFFDDVFVPDTMVVGTVNDGWRLARTTLANERVAMAGGTALGNPMEEV
. .* . :*. .
Mflv_2504|M.gilvum_PYR-GCK LRRVAVRSGVPDYGYAFEP--VRAGAES----------------------
Mvan_4154|M.vanbaalenii_PYR-1 LRRVAVRSGVPDYGYAFEPDPVPSGVRGAA--------------------
MAV_2556|M.avium_104 LRRIATRTGIPDYGYAFWPGRTLEGAVA----------------------
TH_4155|M.thermoresistible__bu LRRIAMRSGIPDYGYAFWPGR-AEGVAS----------------------
MSMEG_6041|M.smegmatis_MC2_155 LRAVEAQPEFDPADQDRLGALIVTAQVGSLLDQRIAQLAVSGQDTGAQAS
** : :. . . . .
Mflv_2504|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4154|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2556|M.avium_104 --------------------------------------------------
TH_4155|M.thermoresistible__bu --------------------------------------------------
MSMEG_6041|M.smegmatis_MC2_155 ARKLIGVRYRQALAEFHMELTEGGGAVRNREVHTFLNTRCLTIAGGTEQI
Mflv_2504|M.gilvum_PYR-GCK --------------
Mvan_4154|M.vanbaalenii_PYR-1 --------------
MAV_2556|M.avium_104 --------------
TH_4155|M.thermoresistible__bu --------------
MSMEG_6041|M.smegmatis_MC2_155 LLTLAGERLLGLPR