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TAEPLRPQTGPVPHASSPLSVPFWEGCRSRQLRYQRCRACDLANFPPTEHCRQCLSDDIGWQQSGGRGEI YSWTVVHRPVTAEFTPPYAPAIITLDEGYQMLTNVVGVPPGDLRVGLRVRVQFHTVAADVTLPYFTAETD GS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5258 | - | - | 100% (143) | hypothetical protein MAV_5258 |
| M. avium 104 | MAV_5264 | - | 9e-16 | 35.65% (115) | acyl dehydratase |
| M. avium 104 | MAV_2640 | - | 2e-15 | 34.96% (123) | hypothetical protein MAV_2640 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 1e-11 | 33.66% (101) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_0635 | - | 2e-16 | 34.88% (129) | hypothetical protein Mflv_0635 |
| M. tuberculosis H37Rv | Rv3542c | - | 2e-11 | 33.66% (101) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0616 | - | 5e-14 | 35.90% (117) | hypothetical protein MAB_0616 |
| M. marinum M | MMAR_4248 | - | 1e-16 | 36.45% (107) | hypothetical protein MMAR_4248 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 9e-16 | 35.61% (132) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3636 | - | 5e-17 | 35.43% (127) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0937 | - | 6e-16 | 36.45% (107) | hypothetical protein MUL_0937 |
| M. vanbaalenii PYR-1 | Mvan_0530 | - | 2e-16 | 34.88% (129) | hypothetical protein Mvan_0530 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
Rv3542c|M.tuberculosis_H37Rv MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
MAB_0616|M.abscessus_ATCC_1997 MS-VVDIQEGFAKIKADGPSAPRLARDPVNQAMINNWVEAMGDRNPIYVD
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
Rv3542c|M.tuberculosis_H37Rv DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
MAB_0616|M.abscessus_ATCC_1997 EEAAKAAGHPGIVAPPAMAQVWTMAGLYGERSGDDPLGRVMALLDSAGYE
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
Rv3542c|M.tuberculosis_H37Rv GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
MAB_0616|M.abscessus_ATCC_1997 SVVATNYEQIYHRYLELGEQVTTTNEVTEVFGPKQTALGESWFINIHAEW
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 ------------------------MTAEPLRPQTGPVPHASSPLSVPFWE
MSMEG_4814|M.smegmatis_MC2_155 ------------------------MSQIPGRPLP-----TVTALNEYFWT
Mflv_0635|M.gilvum_PYR-GCK -------------------------MRRTGPDVAAPPLPSLEGLTAQFYE
Mvan_0530|M.vanbaalenii_PYR-1 -------------------------MRRTGPDVAAPPLPSLEGLTAQFYE
Mb3572c|M.bovis_AF2122/97 QVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPDAMMRPSSSRDTAFFWD
Rv3542c|M.tuberculosis_H37Rv QVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPDAMMRPSSSRDTAFFWD
MAB_0616|M.abscessus_ATCC_1997 HVGDELVNEMNWRIMKFRPGAKKAADVPQDLDPSKLMRPSWSRDSAYFWE
MMAR_4248|M.marinum_M --------------------------------MASRLAPAISPDTEFFWH
MUL_0937|M.ulcerans_Agy99 --------------------------------MASRLAPAISPDTEFFWH
TH_3636|M.thermoresistible__bu ---------------------VSNQSNANEANTNGLPVPEPSAVSAPFWE
. *:
MAV_5258|M.avium_104 GCRSRQLRYQRCRACDLANFPPTEHCRQCLSDDIGWQQSGGRGEIYSWTV
MSMEG_4814|M.smegmatis_MC2_155 AGRDGVLRIQECRSCDALIHPPQPICRYCRSHDLGVRDVSGRATLAGFTV
Mflv_0635|M.gilvum_PYR-GCK HCRREELSFQRCSRCDRWRHVPRLTCAGCGSNSWSWQRSSGRGVVFSHTV
Mvan_0530|M.vanbaalenii_PYR-1 HCRREELSFQRCSRCDRWRHVPRLTCAGCGSNSWSWQRSSGRGVVFSHTV
Mb3572c|M.bovis_AF2122/97 GVKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVV
Rv3542c|M.tuberculosis_H37Rv GVKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVV
MAB_0616|M.abscessus_ATCC_1997 GVAAHELRLQKRPD-GSLQHPPVPAVWQDKEAPIEYQVASGRGTVYSYVV
MMAR_4248|M.marinum_M GLREHKLLIQRCAECGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVM
MUL_0937|M.ulcerans_Agy99 GLREHQLLIQRCAEFGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVM
TH_3636|M.thermoresistible__bu ATRKHRLVMQRCTACRHLVWYPRHVCPRCGGFSLEWEQLSGQGVVYAVSI
* *. * .* . : . :
MAV_5258|M.avium_104 VHRPVTA--EFTPPYAPAIITLDEG--YQMLTNVVGVPPG--DLRVGLRV
MSMEG_4814|M.smegmatis_MC2_155 NERFGFP--DMPPPYVVAEVAIVEDPRVRLTTNIVDCDPQ--SLELGQPV
Mflv_0635|M.gilvum_PYR-GCK IHRALHPGFDEAVPFVCAVVEMDEG--VRMVARIVDLVADGTAMLVDAAV
Mvan_0530|M.vanbaalenii_PYR-1 IHRALHPGFDEAVPFVCAVVEMDEG--VRMVARIVDLVADGTAMLVDAAV
Mb3572c|M.bovis_AF2122/97 HHAPKVP--GRTVPFVIALVELEEG--VRMLGELRGADPA--RVAIGMPV
Rv3542c|M.tuberculosis_H37Rv HHAPKVP--GRTVPFVIALVELEEG--VRMLGELRGADPA--RVAIGMPV
MAB_0616|M.abscessus_ATCC_1997 HHAPQVP--GRTLPFVIALVELDEG--VRMLGELRGVSPD--DVQIGLPV
MMAR_4248|M.marinum_M PHQPRFP--FFDYPYIVVLVELDEG--VRLVSNLCGIDPA--DVTVGMAV
MUL_0937|M.ulcerans_Agy99 PHQPRFP--FFDYPYIVVLVELDEG--VRLVSNLCGIDPA--DVTVGMAV
TH_3636|M.thermoresistible__bu HHRPAHPAFAERVPYSVVLVDLDEG--ARIMSNVFGPPPS-----VGDQV
. . *: . : : *. :: .: . . :. *
MAV_5258|M.avium_104 RVQFHTVAADVTLPYFTAETDGS---------------------------
MSMEG_4814|M.smegmatis_MC2_155 EVSFQHID-DVWLPVFTPSADTTPTPAPVEDIAPQDIGKFVRPMLTEDKF
Mflv_0635|M.gilvum_PYR-GCK EVVYVHAADDVVLPAFRLPAAEVRGNGRR---------------------
Mvan_0530|M.vanbaalenii_PYR-1 EVVYVHAADDVVLPAFRLPAAEVRGNGRR---------------------
Mb3572c|M.bovis_AF2122/97 RATYIDFPD------WSLYAWEPDE-------------------------
Rv3542c|M.tuberculosis_H37Rv RATYIDFPD------WSLYAWEPDE-------------------------
MAB_0616|M.abscessus_ATCC_1997 RATYLDFPAEGEDPAWTLYAWEAA--------------------------
MMAR_4248|M.marinum_M EVFYQDFDGP--DGSFVLHQFRPVALDSEAVR------------------
MUL_0937|M.ulcerans_Agy99 EVFYQDFDGP--DGSFVLHQFRPVALDSEAVR------------------
TH_3636|M.thermoresistible__bu SLTWLRLDDGRNLPVFEPR-------------------------------
: :
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 EDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAVADAGLTFDDIDGLSTY
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 PGLDIAGMGEGGVSVLEGALGLRPTWINGGMDTFGPGGSVIAAMMAISAG
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 LARHVLCFRTLWEATFGQLVKEGKMSPPMSARTNSWQQPYGATSAAHTLA
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 QNAGRHFHRYGTTRETLGWIALNQRANAALNPTAIYREPLTMEDYLSART
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 ITTPFGLYDCDVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIERLD
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 WDQTTLTHEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGL
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 GFCGIGEAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQ
Mflv_0635|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
TH_3636|M.thermoresistible__bu --------------------------------------------------
MAV_5258|M.avium_104 -----------------------------------
MSMEG_4814|M.smegmatis_MC2_155 LRGEAGERQVEDARVAVASSGGLTPSGVLLLRRDD
Mflv_0635|M.gilvum_PYR-GCK -----------------------------------
Mvan_0530|M.vanbaalenii_PYR-1 -----------------------------------
Mb3572c|M.bovis_AF2122/97 -----------------------------------
Rv3542c|M.tuberculosis_H37Rv -----------------------------------
MAB_0616|M.abscessus_ATCC_1997 -----------------------------------
MMAR_4248|M.marinum_M -----------------------------------
MUL_0937|M.ulcerans_Agy99 -----------------------------------
TH_3636|M.thermoresistible__bu -----------------------------------