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VKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQAMYLDRLLNDGLARDWGICGIGVLPDDRRM RDALRSQDYLYTLILEHPDGTQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGYQPPLSA AFELVAEALNRRRERGLPSPTIVSCDNIIKNGDVARRAFTAHAEQVNPELAQWMRENTTFPNSMVDRITP TPTPDLVDRLAAEFGVQDAEPVVAEPFAMWVLEDDFADGRPPLDKAGVRLVDDVAPYEAIKLRLLNAGHQ GLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPTLPRMPGLEDFRDGLIPRFANAYVGDQVARLCA DSSDHIPKWLLPVVHDNLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEVVDRLADTLVPLARSQRENPD AFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4838 | - | - | 100% (467) | mannitol 2-dehydrogenase |
| M. avium 104 | MAV_1052 | - | e-170 | 62.28% (464) | mannitol 2-dehydrogenase |
| M. avium 104 | MAV_1054 | - | 1e-86 | 39.74% (463) | D-mannonate oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0571 | - | 0.0 | 79.23% (467) | mannitol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5576 | - | 1e-176 | 64.52% (465) | D-mannonate oxidoreductase |
| M. thermoresistible (build 8) | TH_0045 | - | 0.0 | 72.52% (484) | D-mannonate oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4838|M.avium_104 ----------MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQ
MMAR_0571|M.marinum_M ----------MKLTAANASALDIPVPNYDRSQISIGIAHFGVGGFHRAHQ
TH_0045|M.thermoresistible__bu ----------MKLNAANLSALSIPTPGYDRGQVRVGIVHFGVGGFHRAHQ
MSMEG_5576|M.smegmatis_MC2_155 MRGVTYTTPPTKLSSSTLEQLTIPHPSYDRAKVQIGIVHFGVGGFHRAHQ
**.: . * ** * ***.:: :**.************
MAV_4838|M.avium_104 AMYLDRLLNDGLARDWGICGIGVLPDDRRMRDALRSQDYLYTLILEHPDG
MMAR_0571|M.marinum_M AMYLDRLLNAGLARDWGICGIGVLPGDERMRDALRSQDHLYTLILEHPDG
TH_0045|M.thermoresistible__bu AMYLDRLLNDGLAGEWGICGVGVLPNDRRMQEALSRQDHLYTLMLAHPDG
MSMEG_5576|M.smegmatis_MC2_155 AMYVDKLLEMGLASEWGICGVGLLANDRRMAEVMEAQDGLYTLLLEHPDG
***:*:**: *** :*****:*:*..*.** :.: ** ****:* ****
MAV_4838|M.avium_104 TQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGY------
MMAR_0571|M.marinum_M TREPRVIGSIVDYRYAPDEPESVIELLADPAIRIISLTITEGGY------
TH_0045|M.thermoresistible__bu TREPRVIGSIVDFRYAPDDPEGVIELLADPAVRIISLTITEGGYNLRDSD
MSMEG_5576|M.smegmatis_MC2_155 HREARVIGSIVDYRYAPDDQEGVIELLAAPTTKIISMTITEGGYYID---
:*.********:****:: .*::*** *: :***:*******
MAV_4838|M.avium_104 ----------------QPPLSAAFELVAEALNRRRERGLPSPTIVSCDNI
MMAR_0571|M.marinum_M ----------------TAPRSAAFELVTEALNRRRQRGHGSPAIVSCDNI
TH_0045|M.thermoresistible__bu AGFDIDNPAVQRDLTGDGPPATVFGLVAAGLARRRERGLPSPTIVSCDNI
MSMEG_5576|M.smegmatis_MC2_155 ----------------SAPEINVFGLVTEALVRRRDRGIGSPTIVSCDNI
* .* **: .* ***:** **:*******
MAV_4838|M.avium_104 IKNGDVARRAFTAHAEQVNPELAQWMRENTTFPNSMVDRITPTPTPDLVD
MMAR_0571|M.marinum_M VENGKVAERAFTSYADMSNPALAQWMRENTRFPNSMVDRITPVTTPELIE
TH_0045|M.thermoresistible__bu VENGDVARRVFTSYAELADPGLAQWMREHTRFPNSMVDRITPVTTPEVID
MSMEG_5576|M.smegmatis_MC2_155 EGNGDVARKAFTTYAERVHPGLGEWMSANTRFPNSMVDRITPVTTPEVIS
**.**.:.**::*: .* *.:** :* ***********..**:::.
MAV_4838|M.avium_104 RLAAEFGVQDAEPVVAEPFAMWVLEDDFADGRPPLDKAGVRLVDDVAPYE
MMAR_0571|M.marinum_M RLDSEFGVRDAWPVAAEPFAMWVLEDDFSHGRPPLEQAGVELVDDVAPYE
TH_0045|M.thermoresistible__bu TLATDFDVEDSWPVVAEPFCMWVLEDDFADGRPPWERAGVKLVDDVRPYE
MSMEG_5576|M.smegmatis_MC2_155 TVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPYE
: :*.* * **.**** *****.*:.**** :..** :**** ***
MAV_4838|M.avium_104 AIKLRLLNAGHQGLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPT
MMAR_0571|M.marinum_M AMKLRLLNAGHQGLCYFAYLAGYRLVHEAAQDPLIADFLCRYFDEEAAPT
TH_0045|M.thermoresistible__bu AMKLRLLNAGHQSLCYFAYLSGYRLVHEAAQDPLFAEFLSRYMDSEAMPT
MSMEG_5576|M.smegmatis_MC2_155 LMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPT
:*******.**.****.**:*** **:**.**::*:** *:*.** **
MAV_4838|M.avium_104 LPRMPG--LEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWLLPVVHD
MMAR_0571|M.marinum_M LTAIGG--LTEFKNGLLPRFANAYVRDTVARLCAESSDRIPKWLLPVVRD
TH_0045|M.thermoresistible__bu LQPVPG--LHEFKDQLIPRFANAHVRDTIARLCAESSDRIPKWLLPVIRD
MSMEG_5576|M.smegmatis_MC2_155 LQPVPGIDLDEYKHTLIERFANPGVRDTIARLCYGSSDRIPKWLVPVIRE
* : * * :::. *: ****. * * :**** ***:*****:**:::
MAV_4838|M.avium_104 NLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEVVDRLADTLVPLARSQR
MMAR_0571|M.marinum_M NLRSTGPVRLSAAIVASWARYAEGIDEAGQPIEVVDRLADTLGPIARSQR
TH_0045|M.thermoresistible__bu NLASGGPVRLAAATVASWARYAEGVDEQGEPIDVVDRLADTLIPIARSQR
MSMEG_5576|M.smegmatis_MC2_155 NLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLADTLVPIALSQR
** : .*::*:** **********:** *.**:* *:***** *:* ***
MAV_4838|M.avium_104 ENPDAFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADG
MMAR_0571|M.marinum_M HDARAFLANRAVFGDLIDQPRFVQPYLWALDSLHRVGARATLQALLDKDG
TH_0045|M.thermoresistible__bu DNPPAFIENRAIFGDLVDQPRFVEAYRWALESLHRVGARATLEALLRERS
MSMEG_5576|M.smegmatis_MC2_155 EHPTAFIENTEVFGDLASSQRFVDEYLWALDSLHRHGARATLESLRS---
... **: * :**** . ** : * ***:**** ******.:*
MAV_4838|M.avium_104 S
MMAR_0571|M.marinum_M S
TH_0045|M.thermoresistible__bu -
MSMEG_5576|M.smegmatis_MC2_155 -