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M. smegmatis MC2 155 MSMEG_5576 (-)

annotation: D-mannonate oxidoreductase
coordinates: 5664415 - 5665851
length: 478

MRGVTYTTPPTKLSSSTLEQLTIPHPSYDRAKVQIGIVHFGVGGFHRAHQAMYVDKLLEMGLASEWGICG
VGLLANDRRMAEVMEAQDGLYTLLLEHPDGHREARVIGSIVDYRYAPDDQEGVIELLAAPTTKIISMTIT
EGGYYIDSAPEINVFGLVTEALVRRRDRGIGSPTIVSCDNIEGNGDVARKAFTTYAERVHPGLGEWMSAN
TRFPNSMVDRITPVTTPEVISTVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPY
ELMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPTLQPVPGIDLDEYKHTLIER
FANPGVRDTIARLCYGSSDRIPKWLVPVIRENLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLA
DTLVPIALSQREHPTAFIENTEVFGDLASSQRFVDEYLWALDSLHRHGARATLESLRS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5576--100% (478)D-mannonate oxidoreductase
M. smegmatis MC2 155MSMEG_2907-2e-6531.66% (477) oxidoreductase YeiQ

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0571-0.066.88% (465) mannitol dehydrogenase
M. avium 104MAV_4838-1e-17664.52% (465) mannitol 2-dehydrogenase
M. thermoresistible (build 8)TH_0045-0.068.39% (484) D-mannonate oxidoreductase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0571|M.marinum_M               ----------MKLTAANASALDIPVPNYDRSQISIGIAHFGVGGFHRAHQ
MAV_4838|M.avium_104                ----------MKLNAHNLTGLKIPVPTYDRSQIGIGIAHFGVGGFHRAHQ
TH_0045|M.thermoresistible__bu      ----------MKLNAANLSALSIPTPGYDRGQVRVGIVHFGVGGFHRAHQ
MSMEG_5576|M.smegmatis_MC2_155      MRGVTYTTPPTKLSSSTLEQLTIPHPSYDRAKVQIGIVHFGVGGFHRAHQ
                                               **.: .   * ** * ***.:: :**.************

MMAR_0571|M.marinum_M               AMYLDRLLNAGLARDWGICGIGVLPGDERMRDALRSQDHLYTLILEHPDG
MAV_4838|M.avium_104                AMYLDRLLNDGLARDWGICGIGVLPDDRRMRDALRSQDYLYTLILEHPDG
TH_0045|M.thermoresistible__bu      AMYLDRLLNDGLAGEWGICGVGVLPNDRRMQEALSRQDHLYTLMLAHPDG
MSMEG_5576|M.smegmatis_MC2_155      AMYVDKLLEMGLASEWGICGVGLLANDRRMAEVMEAQDGLYTLLLEHPDG
                                    ***:*:**: *** :*****:*:*..*.** :.:  ** ****:* ****

MMAR_0571|M.marinum_M               TREPRVIGSIVDYRYAPDEPESVIELLADPAIRIISLTITEGGY------
MAV_4838|M.avium_104                TQEPRVIGSIVDFRYAPEDPGSVVDLLADPATRIISLTITEGGY------
TH_0045|M.thermoresistible__bu      TREPRVIGSIVDFRYAPDDPEGVIELLADPAVRIISLTITEGGYNLRDSD
MSMEG_5576|M.smegmatis_MC2_155      HREARVIGSIVDYRYAPDDQEGVIELLAAPTTKIISMTITEGGYYID---
                                     :*.********:****::  .*::*** *: :***:*******      

MMAR_0571|M.marinum_M               ----------------TAPRSAAFELVTEALNRRRQRGHGSPAIVSCDNI
MAV_4838|M.avium_104                ----------------QPPLSAAFELVAEALNRRRERGLPSPTIVSCDNI
TH_0045|M.thermoresistible__bu      AGFDIDNPAVQRDLTGDGPPATVFGLVAAGLARRRERGLPSPTIVSCDNI
MSMEG_5576|M.smegmatis_MC2_155      ----------------SAPEINVFGLVTEALVRRRDRGIGSPTIVSCDNI
                                                      *   .* **: .* ***:**  **:*******

MMAR_0571|M.marinum_M               VENGKVAERAFTSYADMSNPALAQWMRENTRFPNSMVDRITPVTTPELIE
MAV_4838|M.avium_104                IKNGDVARRAFTAHAEQVNPELAQWMRENTTFPNSMVDRITPTPTPDLVD
TH_0045|M.thermoresistible__bu      VENGDVARRVFTSYAELADPGLAQWMREHTRFPNSMVDRITPVTTPEVID
MSMEG_5576|M.smegmatis_MC2_155      EGNGDVARKAFTTYAERVHPGLGEWMSANTRFPNSMVDRITPVTTPEVIS
                                      **.**.:.**::*:  .* *.:**  :* ***********..**:::.

MMAR_0571|M.marinum_M               RLDSEFGVRDAWPVAAEPFAMWVLEDDFSHGRPPLEQAGVELVDDVAPYE
MAV_4838|M.avium_104                RLAAEFGVQDAEPVVAEPFAMWVLEDDFADGRPPLDKAGVRLVDDVAPYE
TH_0045|M.thermoresistible__bu      TLATDFDVEDSWPVVAEPFCMWVLEDDFADGRPPWERAGVKLVDDVRPYE
MSMEG_5576|M.smegmatis_MC2_155      TVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPYE
                                     :  :*.* *  **.****  *****.*:.**** :..** :**** ***

MMAR_0571|M.marinum_M               AMKLRLLNAGHQGLCYFAYLAGYRLVHEAAQDPLIADFLCRYFDEEAAPT
MAV_4838|M.avium_104                AIKLRLLNAGHQGLCYFAYLAGYREVHEAAQDPVIAEFLARYMDSEAMPT
TH_0045|M.thermoresistible__bu      AMKLRLLNAGHQSLCYFAYLSGYRLVHEAAQDPLFAEFLSRYMDSEAMPT
MSMEG_5576|M.smegmatis_MC2_155      LMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPT
                                     :*******.**.****.**:*** **:**.**::*:**  *:*.** **

MMAR_0571|M.marinum_M               LTAIGG--LTEFKNGLLPRFANAYVRDTVARLCAESSDRIPKWLLPVVRD
MAV_4838|M.avium_104                LPRMPG--LEDFRDGLIPRFANAYVGDQVARLCADSSDHIPKWLLPVVHD
TH_0045|M.thermoresistible__bu      LQPVPG--LHEFKDQLIPRFANAHVRDTIARLCAESSDRIPKWLLPVIRD
MSMEG_5576|M.smegmatis_MC2_155      LQPVPGIDLDEYKHTLIERFANPGVRDTIARLCYGSSDRIPKWLVPVIRE
                                    *  : *  * :::. *: ****. * * :****  ***:*****:**:::

MMAR_0571|M.marinum_M               NLRSTGPVRLSAAIVASWARYAEGIDEAGQPIEVVDRLADTLGPIARSQR
MAV_4838|M.avium_104                NLRSGGPVQLSAAIVASWARYAEGVDEQGRPIEVVDRLADTLVPLARSQR
TH_0045|M.thermoresistible__bu      NLASGGPVRLAAATVASWARYAEGVDEQGEPIDVVDRLADTLIPIARSQR
MSMEG_5576|M.smegmatis_MC2_155      NLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLADTLVPIALSQR
                                    ** : .*::*:** **********:** *.**:* *:***** *:* ***

MMAR_0571|M.marinum_M               HDARAFLANRAVFGDLIDQPRFVQPYLWALDSLHRVGARATLQALLDKDG
MAV_4838|M.avium_104                ENPDAFLANRAVFGDLIDAPRFREAYRWALDSLHRRGARATLRALIGADG
TH_0045|M.thermoresistible__bu      DNPPAFIENRAIFGDLVDQPRFVEAYRWALESLHRVGARATLEALLRERS
MSMEG_5576|M.smegmatis_MC2_155      EHPTAFIENTEVFGDLASSQRFVDEYLWALDSLHRHGARATLESLRS---
                                    ... **: *  :**** .  ** : * ***:**** ******.:*     

MMAR_0571|M.marinum_M               S
MAV_4838|M.avium_104                S
TH_0045|M.thermoresistible__bu      -
MSMEG_5576|M.smegmatis_MC2_155      -