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EADGINLNNATLPTLPIEAPNYDRGSVTVGIAHIGAGHFHRAHQAMYIDRLLQAGLAREWGICGVGVMPA DWTMRDVLNDQDGLYTLILEKPDGSRDAHVIGSIIDYRYAPDDPESALEVLAAPTTRIISLTITEGGYRD PEGPAFAFIVEALDRRRRRGIAAPTIASCDNIENNGEIARRAVLANAEARSPELAEWVDEHVCFPSSMVD RITPSTTLQMAAEVRRDFGVNDRWPVVAEPFTAWVLEDKFADGRPPLERAGVLLVDDVAPYELMKLRMLN AGHQCLAYFAHLCGFEFVHEAARDPLFAEYLWAYFESEAIPTLPPVPGIDLYDYGHRLIERFTNPGVRDT IARLCAFSSDRIPKWLLPVINDNLANDGSVRIAAAAVASWARYAEGTDEWGKPFEVVDQLADSLIPIARS QYENPTAFIEIAGVFGDLAHQPRFVQAYSWALESLHRKGARATLEELVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1052 | - | - | 100% (470) | mannitol 2-dehydrogenase |
| M. avium 104 | MAV_4838 | - | e-170 | 62.28% (464) | mannitol 2-dehydrogenase |
| M. avium 104 | MAV_1054 | - | 9e-91 | 39.52% (458) | D-mannonate oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0571 | - | 1e-169 | 62.50% (464) | mannitol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5576 | - | 1e-176 | 64.66% (464) | D-mannonate oxidoreductase |
| M. thermoresistible (build 8) | TH_0045 | - | 1e-174 | 63.24% (487) | D-mannonate oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0571|M.marinum_M ----------MKLTAANASALDIPVPNYDRSQISIGIAHFGVGGFHRAHQ
TH_0045|M.thermoresistible__bu ----------MKLNAANLSALSIPTPGYDRGQVRVGIVHFGVGGFHRAHQ
MSMEG_5576|M.smegmatis_MC2_155 MRGVTYTTPPTKLSSSTLEQLTIPHPSYDRAKVQIGIVHFGVGGFHRAHQ
MAV_1052|M.avium_104 -----MEADGINLNNATLPTLPIEAPNYDRGSVTVGIAHIGAGHFHRAHQ
:*. :. * * *.***..: :**.*:*.* ******
MMAR_0571|M.marinum_M AMYLDRLLNAGLARDWGICGIGVLPGDERMRDALRSQDHLYTLILEHPDG
TH_0045|M.thermoresistible__bu AMYLDRLLNDGLAGEWGICGVGVLPNDRRMQEALSRQDHLYTLMLAHPDG
MSMEG_5576|M.smegmatis_MC2_155 AMYVDKLLEMGLASEWGICGVGLLANDRRMAEVMEAQDGLYTLLLEHPDG
MAV_1052|M.avium_104 AMYIDRLLQAGLAREWGICGVGVMPADWTMRDVLNDQDGLYTLILEKPDG
***:*:**: *** :*****:*::. * * :.: ** ****:* :***
MMAR_0571|M.marinum_M TREPRVIGSIVDYRYAPDEPESVIELLADPAIRIISLTITEGGY------
TH_0045|M.thermoresistible__bu TREPRVIGSIVDFRYAPDDPEGVIELLADPAVRIISLTITEGGYNLRDSD
MSMEG_5576|M.smegmatis_MC2_155 HREARVIGSIVDYRYAPDDQEGVIELLAAPTTKIISMTITEGGYYID---
MAV_1052|M.avium_104 SRDAHVIGSIIDYRYAPDDPESALEVLAAPTTRIISLTITEGGY------
*:.:*****:*:*****: *..:*:** *: :***:*******
MMAR_0571|M.marinum_M ----------------TAPRSAAFELVTEALNRRRQRGHGSPAIVSCDNI
TH_0045|M.thermoresistible__bu AGFDIDNPAVQRDLTGDGPPATVFGLVAAGLARRRERGLPSPTIVSCDNI
MSMEG_5576|M.smegmatis_MC2_155 ----------------SAPEINVFGLVTEALVRRRDRGIGSPTIVSCDNI
MAV_1052|M.avium_104 ----------------RDPEGPAFAFIVEALDRRRRRGIAAPTIASCDNI
* .* ::. .* *** ** :*:*.*****
MMAR_0571|M.marinum_M VENGKVAERAFTSYADMSNPALAQWMRENTRFPNSMVDRITPVTTPELIE
TH_0045|M.thermoresistible__bu VENGDVARRVFTSYAELADPGLAQWMREHTRFPNSMVDRITPVTTPEVID
MSMEG_5576|M.smegmatis_MC2_155 EGNGDVARKAFTTYAERVHPGLGEWMSANTRFPNSMVDRITPVTTPEVIS
MAV_1052|M.avium_104 ENNGEIARRAVLANAEARSPELAEWVDEHVCFPSSMVDRITPSTTLQMAA
**.:*.:.. : *: * *.:*: :. **.******** ** ::
MMAR_0571|M.marinum_M RLDSEFGVRDAWPVAAEPFAMWVLEDDFSHGRPPLEQAGVELVDDVAPYE
TH_0045|M.thermoresistible__bu TLATDFDVEDSWPVVAEPFCMWVLEDDFADGRPPWERAGVKLVDDVRPYE
MSMEG_5576|M.smegmatis_MC2_155 TVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPYE
MAV_1052|M.avium_104 EVRRDFGVNDRWPVVAEPFTAWVLEDKFADGRPPLERAGVLLVDDVAPYE
: :*.* * ***.**** *****.*:.**** *..** :**** ***
MMAR_0571|M.marinum_M AMKLRLLNAGHQGLCYFAYLAGYRLVHEAAQDPLIADFLCRYFDEEAAPT
TH_0045|M.thermoresistible__bu AMKLRLLNAGHQSLCYFAYLSGYRLVHEAAQDPLFAEFLSRYMDSEAMPT
MSMEG_5576|M.smegmatis_MC2_155 LMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPT
MAV_1052|M.avium_104 LMKLRMLNAGHQCLAYFAHLCGFEFVHEAARDPLFAEYLWAYFESEAIPT
****:***.** *.**.:*.*:.:**:** ***:*::* *::.** **
MMAR_0571|M.marinum_M LTAIGG--LTEFKNGLLPRFANAYVRDTVARLCAESSDRIPKWLLPVVRD
TH_0045|M.thermoresistible__bu LQPVPG--LHEFKDQLIPRFANAHVRDTIARLCAESSDRIPKWLLPVIRD
MSMEG_5576|M.smegmatis_MC2_155 LQPVPGIDLDEYKHTLIERFANPGVRDTIARLCYGSSDRIPKWLVPVIRE
MAV_1052|M.avium_104 LPPVPGIDLYDYGHRLIERFTNPGVRDTIARLCAFSSDRIPKWLLPVIND
* .: * * :: . *: **:*. ****:**** *********:**:.:
MMAR_0571|M.marinum_M NLRSTGPVRLSAAIVASWARYAEGIDEAGQPIEVVDRLADTLGPIARSQR
TH_0045|M.thermoresistible__bu NLASGGPVRLAAATVASWARYAEGVDEQGEPIDVVDRLADTLIPIARSQR
MSMEG_5576|M.smegmatis_MC2_155 NLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLADTLVPIALSQR
MAV_1052|M.avium_104 NLANDGSVRIAAAAVASWARYAEGTDEWGKPFEVVDQLADSLIPIARSQY
** . ..:*::** ********** ** *:*::* *:***:* *** **
MMAR_0571|M.marinum_M HDARAFLANRAVFGDLIDQPRFVQPYLWALDSLHRVGARATLQALLDKDG
TH_0045|M.thermoresistible__bu DNPPAFIENRAIFGDLVDQPRFVEAYRWALESLHRVGARATLEALLRERS
MSMEG_5576|M.smegmatis_MC2_155 EHPTAFIENTEVFGDLASSQRFVDEYLWALDSLHRHGARATLESLRS---
MAV_1052|M.avium_104 ENPTAFIEIAGVFGDLAHQPRFVQAYSWALESLHRKGARATLEELVR---
... **: :**** . ***: * ***:**** ******: *
MMAR_0571|M.marinum_M S
TH_0045|M.thermoresistible__bu -
MSMEG_5576|M.smegmatis_MC2_155 -
MAV_1052|M.avium_104 -