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VIIALVAAISGMLYGYDTGVISWALLQLTQDFNITEGWQQVIAASILLGAVAGALTCSWLSDLRGRRGTL LMLAVVFIVGALWCADAADSVMLSLGRLVLGFAVGGATQTAPMYVAELAPPAYRGRLVLCFQIAIGVGIL TATLVGAGGSISWRGPIGLACVPAAIMLWLLLRLPESPRWLVKKDNRDAARAVLEHVRPEGYDVAAELDE ATELARVERTAATRGWRGLRDAWVRPALVLGCGIAVFTQLSGIEMIIYYSPTILTDDGVYRSVALQVSVC LGAAYLIAQLVGLAIIDRVGRRRLTLIMVPGAAISLFALGLLFITSDSGRDVIPYIMICLIAFMLFNGGG LQLMGWLTGSETYPLAVRPAATALQSATLWGTNLVITLTMLSLIKAIGVGPSMWLYALFNVAAWIFVFFR MPDLTGKTLEEIEYQLSEGKFRPSDFGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4814 | - | - | 100% (449) | metabolite/sugar transport protein |
| M. avium 104 | MAV_4306 | - | 3e-52 | 30.80% (448) | transporter, major facilitator superfamily protein |
| M. avium 104 | MAV_3053 | - | 6e-17 | 25.00% (356) | sugar transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 2e-53 | 32.09% (455) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_3055 | - | 6e-48 | 30.13% (468) | sugar transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 1e-52 | 31.87% (455) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | MLBr_01562 | - | 4e-06 | 26.77% (198) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_0365c | - | 2e-53 | 32.00% (450) | sugar-transport integral membrane protein |
| M. marinum M | MMAR_1191 | sugI | 2e-52 | 30.94% (446) | sugar-transport integral membrane protein SugI |
| M. smegmatis MC2 155 | MSMEG_5559 | - | 0.0 | 75.95% (449) | metabolite/sugar transport protein |
| M. thermoresistible (build 8) | TH_2640 | - | 1e-24 | 28.43% (313) | PUTATIVE sugar transporter |
| M. ulcerans Agy99 | MUL_1444 | sugI | 3e-53 | 31.17% (446) | sugar-transport integral membrane protein SugI |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 1e-46 | 30.45% (463) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4814|M.avium_104 --------------------------------------------------
MSMEG_5559|M.smegmatis_MC2_155 ------------------------------MSTDTQDSADARAKTPGQLT
Mflv_3055|M.gilvum_PYR-GCK --------------------------MAGQGGPAGESPELYEKGQDFSSG
Mvan_3472|M.vanbaalenii_PYR-1 --------------------------MAGQGGPVGDGPEIFEQGQEFSSG
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 --MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSG
Rv3331|M.tuberculosis_H37Rv --MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSG
MMAR_1191|M.marinum_M -------------------------------------------------M
MUL_1444|M.ulcerans_Agy99 -------------------------------------------------M
MAB_0365c|M.abscessus_ATCC_199 ---------------------------------------MSLITDLRSTS
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MAV_4814|M.avium_104 --MVIIALVAAISG--MLYGYDTGVISWALLQLTQDFNITEGWQQVIAAS
MSMEG_5559|M.smegmatis_MC2_155 GAVVIVALVSAVSG--MLYGYDTGIISGALLQITKDFSIAEAWKQVIAAS
Mflv_3055|M.gilvum_PYR-GCK KTAIRIASVAALGG--LLFGYDSAVINGAVASIQEDFGIGNYALGLAVAS
Mvan_3472|M.vanbaalenii_PYR-1 KTAVRIASVAALGG--LLFGYDSAVINGAVDSIQEDFGIGNAELGFAVAS
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 RRALLVGLTAASVG--VLYGYDLSAIAGALLSLSEEFELTTREQELLTTT
Rv3331|M.tuberculosis_H37Rv RRALLVGLTAASVG--VLYGYDLSAIAGALLSLSEEFELTTREQELLTTT
MMAR_1191|M.marinum_M QRGILVALTAASVG--LIYGYDLSIIAGAQLFITEEFGLSTHQQELLTTM
MUL_1444|M.ulcerans_Agy99 QRGILVALTAASVG--LIYGYDLSIIAGAQLFITEEFGLSTHQQELLTTM
MAB_0365c|M.abscessus_ATCC_199 RLGVMVAVTAAAVG--VIYGYDSSNIAGALLFLTEDLHLSTHDQQVAATA
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
MAV_4814|M.avium_104 ILLGAVAGALTCSWLSDLRGRRGTLLMLAVVFIVGALWCADAADSVMLSL
MSMEG_5559|M.smegmatis_MC2_155 ILLGAVIGALVCSHLSQKRGRKGTLLMLAVVFVIGSLWCAISPNPVLLSV
Mflv_3055|M.gilvum_PYR-GCK ALLGAAVGALSAGRIADRIGRIAVMKIAAVLFLLSAFGTAFAPETITLVI
Mvan_3472|M.vanbaalenii_PYR-1 ALLGAAAGAMTAGRIADRIGRIAVMKIAAVLFLVSAFGTGFAHEVWAVVL
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVV
Rv3331|M.tuberculosis_H37Rv AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVV
MMAR_1191|M.marinum_M VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGSLSVSLPMLLA
MUL_1444|M.ulcerans_Agy99 VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGALSVSLPMLLA
MAB_0365c|M.abscessus_ATCC_199 VVIGEIFGALIGGPLSNKIGRKRSMVLVAATFGIFSLLSALAVDLNTLAA
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
MAV_4814|M.avium_104 GRLVLGFAVGGATQTAPMYVAELAPPA-YRGRLVLCFQIAIGVGILTATL
MSMEG_5559|M.smegmatis_MC2_155 GRLVLGFAVGGATQTAPMYVAELSPPK-YRGRLVLCFQIAIGVGIVIATI
Mflv_3055|M.gilvum_PYR-GCK GRIVGGVGVGVASVIAPAYIAETSPPG-IRGRLGSLQQLAIVSGIFASFA
Mvan_3472|M.vanbaalenii_PYR-1 FRIVGGIGVGVASVIAPAYIAETSPPG-IRGRLGSLQQLAIVSGIFASFA
TH_2640|M.thermoresistible__bu --------------------------------------LAIVSGIFLSLL
Mb3364|M.bovis_AF2122/97 ARLLLGVTIGLSVVVVPVYVAESAPAA-VRGSLVTAYQLATLSGIVVGYL
Rv3331|M.tuberculosis_H37Rv ARLLLGVTIGLSVVVVPVYVAESAPAA-VRGSLVTAYQLATLSGIVVGYL
MMAR_1191|M.marinum_M ARFLLGLAVGVSIVVVPVYVAESAPAA-VRGSLLTVYQLTTVSGLIVGYL
MUL_1444|M.ulcerans_Agy99 ARFLLGLAVGVSIVVVPVYVAESAPAA-VRGSLLTVYQLTTVSGLIVGYL
MAB_0365c|M.abscessus_ATCC_199 ARFLLGLTVGVSVVVVPVFVAESSPTK-IRGSMLVLYQLACVTGIIAGYL
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
* . .
MAV_4814|M.avium_104 VG---------AGGSIS--------WRGPIGLACVPAAIMLWLLLRLPES
MSMEG_5559|M.smegmatis_MC2_155 VG---------ASEHIP--------WRWSIGAAAVPAAIMLVLLLRLPES
Mflv_3055|M.gilvum_PYR-GCK VNYLLQW---LAGGPNEPLWLGMDAWRWMFLAMAVPAVVYGGLAFTIPES
Mvan_3472|M.vanbaalenii_PYR-1 VNWLLQW---AAGGPNEPLWFGLDAWRWMFLAMALPAVLYGVLAFTIPES
TH_2640|M.thermoresistible__bu IDGILAA---LAGGSREELWLNMEAWRWMFLMMAVPAVLYGALTFTIPES
Mb3364|M.bovis_AF2122/97 VGYLLAGSHG---------------WRAMFGLAAAPATLLLPLLWRMPDT
Rv3331|M.tuberculosis_H37Rv VGYLLAGSHG---------------WRAMFGLAAAPATLLLPLLWRMPDT
MMAR_1191|M.marinum_M TGYLLAGTHS---------------WRWMLGLATVPAMLLLPLLIRMPDT
MUL_1444|M.ulcerans_Agy99 TGYLLAGTHS---------------WRWMLGLATVPAMLLLPLLIRMPDT
MAB_0365c|M.abscessus_ATCC_199 IAWALSSTGS---------------WRLMLGLAAVPAALVLIALLKLPDT
MLBr_01562|M.leprae_Br4923 VGGALTEVS----------------WRLAFLVNVPIGLVMIYLARTALHE
** : . : .
MAV_4814|M.avium_104 PRWLVKKDNRDAARAVLEHVRPEGYDVAAELDEATELARVERTAATR-GW
MSMEG_5559|M.smegmatis_MC2_155 PRWLIKDGDPDKAREVLERVRPDGYDIDGELDEMTTLVRKEQTAKTR-GW
Mflv_3055|M.gilvum_PYR-GCK PRYLVATHKIPEARRVLSMLLGQ-KNLEITITRIRETLEREDRPSWR-DL
Mvan_3472|M.vanbaalenii_PYR-1 PRYLVASHKIPEARRVLSMLLGK-KNLEITITRIRETLEREDKPSWR-DM
TH_2640|M.thermoresistible__bu PRYLVATHRVPEARRVLSRLLGA-KNLEITINRIERSLRAEKPPSWS-DL
Mb3364|M.bovis_AF2122/97 ARWYLLKGRIADARSALRRIQPE-ADIDAELADMAAAVDERGGG-----I
Rv3331|M.tuberculosis_H37Rv ARWYLLKGRIADARSALRRIQPE-ADIDAELADMAAAVDERGGG-----I
MMAR_1191|M.marinum_M PRWYVMKGRIQEARAALLRVDPA-ADVEEELAEIGTALSEGSGG-----V
MUL_1444|M.ulcerans_Agy99 PRWYVMKGRIQEARAALLRVDPA-ADVEEELAEIGTALSEGSGG-----V
MAB_0365c|M.abscessus_ATCC_199 ARWYMMRGDRARAREVLSMVDRD-VDIDHELDEIAEALRAEGGGSVRARL
MLBr_01562|M.leprae_Br4923 THKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVA
.: * . .
MAV_4814|M.avium_104 RGLRDAWVRPALVLGCGIAVFTQLSGIE--MIIYYSPTILTDDGVY----
MSMEG_5559|M.smegmatis_MC2_155 PGLRAAWVRPALILGCGIAIFTQLSGIE--MIIYYSPTILTDNGFS----
Mflv_3055|M.gilvum_PYR-GCK KKPTGGIYG-IVWVGLGLSIFQQFVGIN--VIFYYSNVLWQAVGFS----
Mvan_3472|M.vanbaalenii_PYR-1 RKPTGGLYG-IVWVGLGLSIFQQFVGIN--VIFYYSNVLWQAVGFS----
TH_2640|M.thermoresistible__bu RKPTGGMYG-IVWVGLGLSIFQQFVGIN--VIFYYSNVLWEAVGFD----
Mb3364|M.bovis_AF2122/97 GEMVRRPYLRATLFVIALGFLVQITGIN--AIIYYSPRLFAAMGFAG---
Rv3331|M.tuberculosis_H37Rv GEMVRRPYLRATLFVIALGFLVQITGIN--AIIYYSPRLFAAMGFAG---
MMAR_1191|M.marinum_M SEMLRPPFLRATIFVITLGFLIQITGIN--AIIYYSPRIFEAMGFTG---
MUL_1444|M.ulcerans_Agy99 SEMLRPPFLRATIFVITLGFLIQITGIN--AIIYYSPRIFEAMGFTG---
MAB_0365c|M.abscessus_ATCC_199 REMVTAPYRRATFFVVGLGFFIQITGIN--AVVYYGPRIFEAMGMSG---
MLBr_01562|M.leprae_Br4923 AIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLY
: .: : : .: . : .
MAV_4814|M.avium_104 RSVALQVSVCLGAAYLIAQLVGLAIIDRVG-------RRRLTLIMVPGAA
MSMEG_5559|M.smegmatis_MC2_155 ESVALQVSVALGVSYLVAQLVGLSIIDKVG-------RRRLTLIMIPGAA
Mflv_3055|M.gilvum_PYR-GCK ADESAVYTVITSVVNVLTTLIAIALIDKIG-------RKPLLLIGSVGMA
Mvan_3472|M.vanbaalenii_PYR-1 ADESAVYTVITSVINVLTTLIAIALIDKIG-------RKPLLLIGSSGMA
TH_2640|M.thermoresistible__bu ESQSFLITVITSVTNIVTTLIAIALIDKIG-------RKPLLLIGSTGMA
Mb3364|M.bovis_AF2122/97 YFAMLALPAMVQVAGLAAVCASLFLVDRLG-------RRPILLSGIATMI
Rv3331|M.tuberculosis_H37Rv YFAMLALPAMVQVAGLAAVCASLFLVDRLG-------RRPILLSGIATMI
MMAR_1191|M.marinum_M DFALLGLPALVQIAGVAAVITSLLLVDRVG-------RRPILLSGIAIMI
MUL_1444|M.ulcerans_Agy99 DFALLGLPALVQIAGVAAVITSLLLVDRVG-------RRPILLSGIAIMI
MAB_0365c|M.abscessus_ATCC_199 YFAKLGLPALVQVAALLAVFISMSSIDRMG-------RRPILMIGIGIMI
MLBr_01562|M.leprae_Br4923 IQDILGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLL
.. . . .: :. :
MAV_4814|M.avium_104 ISLFALGLLFITSDSG------------RDVIPYIMICLIAFMLFNGGGL
MSMEG_5559|M.smegmatis_MC2_155 VSLFVLGTLFATGHSG------------RDSVPFIVACLVVFMLFNAGGL
Mflv_3055|M.gilvum_PYR-GCK VTLSTMAFIFANAELIENEAGEMVPSLPGASGVIALIAANLFVVAFGMSW
Mvan_3472|M.vanbaalenii_PYR-1 VTLITMAVIFANATVGADGN----PSLPGASGVIALIAANLFVVAFGMSW
TH_2640|M.thermoresistible__bu GTLGVMAVIFGTAPVIDGQP-----QLGDVAGPVALVAANLFVVSFGMSW
Mb3364|M.bovis_AF2122/97 TADAVLITVFANDSD------------GGTGLVLGFAGVLLFIIGFNFGF
Rv3331|M.tuberculosis_H37Rv TADAVLITVFANDSD------------GGTGLVLGFAGVLLFIIGFNFGF
MMAR_1191|M.marinum_M VADVALMAVFAR---------------GQGAAILGFAGILLFIIGYTMGF
MUL_1444|M.ulcerans_Agy99 VADVALMAVFAR---------------GQGAAILGFAGILLFIIGYTMGF
MAB_0365c|M.abscessus_ATCC_199 VADALLVGVFAVGGSS----------FGGLLTFLGFLGIVLIAVGFTFGF
MLBr_01562|M.leprae_Br4923 MVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAG-VGF
* . : .
MAV_4814|M.avium_104 QLMGWLTGSETYPLAVR-----PAATALQSATLWGTNLVITLTMLSLIKA
MSMEG_5559|M.smegmatis_MC2_155 QLMGWLTGSETYPLAVR-----PAGTAAQSAALWGTNLLITLTLLTLISG
Mflv_3055|M.gilvum_PYR-GCK GPVVWVLLGEMFPNRIR-----AAALGLAAAGQWTANWVITVSFPELRNF
Mvan_3472|M.vanbaalenii_PYR-1 GPVVWVLLGEMFPNRIR-----AAALGLAAAGQWAANWLITVTFPGLREH
TH_2640|M.thermoresistible__bu GPVVWVLLGEMFPNRIR-----AAALGLAAAGQWTANWVITVTFPGLREH
Mb3364|M.bovis_AF2122/97 GSLVWVYAAESFPSRLR-----SMGSSLMLTSTLTANAIVAAFSLTMLRV
Rv3331|M.tuberculosis_H37Rv GSLVWVYAAESFPSRLR-----SMGSSPMLTSTLTANAIVAAFSLTMLRV
MMAR_1191|M.marinum_M GSLGWVYASESFPTRLR-----SIGSSTMLTANLIANAIVAGVFLTMLHS
MUL_1444|M.ulcerans_Agy99 GSLGWVYASESFPTRLR-----SIGSSTMLTANLIANAIVAAVFLTMLHS
MAB_0365c|M.abscessus_ATCC_199 GSLVWVYAGESFPARLR-----SYGASAMLTSDLVANAVVSMYFLTLLTA
MLBr_01562|M.leprae_Br4923 DRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQ
: : : . . : .
MAV_4814|M.avium_104 IGVGPSMWLYALFNVAAWIFVFFRMPDLTGKTLEEIEYQLSEGKFRPSDF
MSMEG_5559|M.smegmatis_MC2_155 IGVGPAMWLYGLFNVAAWLFVYFRMPDLTGRSLEEIEGKLRDGKFRPADF
Mflv_3055|M.gilvum_PYR-GCK LGA--AYGFYALCAVLSGLFVWKWVRETKGVSLEDMHGEILHGDKS-ATG
Mvan_3472|M.vanbaalenii_PYR-1 LGL--AYGFYGLCAVLSGLFVWRWVMETKGVSLEDMHGEILHADKT-ATG
TH_2640|M.thermoresistible__bu LGP--AYGFYALCAVLSLLFVWRWVAETKGRTLEDMQPDVPGHDRASAPG
Mb3364|M.bovis_AF2122/97 LGGAGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAER
Rv3331|M.tuberculosis_H37Rv LGGAGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAER
MMAR_1191|M.marinum_M LGGSGAFAVFGVLALVAFGVVYRYAPETKGRQLEEIRHFWENGGRWPEKL
MUL_1444|M.ulcerans_Agy99 LGGSGAFAVFGVLALVAFGVVYRYAPETKGRQLEEIRHFWENGGRWPEKL
MAB_0365c|M.abscessus_ATCC_199 LGGVVAFGVFGVLATAALVFVHVLAPETKGRNLEEIRHFWESGGTWPET-
MLBr_01562|M.leprae_Br4923 LRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGE
: :. . .: * *::
MAV_4814|M.avium_104 GR-----
MSMEG_5559|M.smegmatis_MC2_155 AR-----
Mflv_3055|M.gilvum_PYR-GCK -------
Mvan_3472|M.vanbaalenii_PYR-1 -------
TH_2640|M.thermoresistible__bu -------
Mb3364|M.bovis_AF2122/97 SPAADEP
Rv3331|M.tuberculosis_H37Rv SPAADEP
MMAR_1191|M.marinum_M TEAP---
MUL_1444|M.ulcerans_Agy99 TEAP---
MAB_0365c|M.abscessus_ATCC_199 -------
MLBr_01562|M.leprae_Br4923 L------