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VRITGIVERAVRLDAPGRGGPANAVVDFSGHTVSLVAVLTDAVRRGRPVAGVAFDSIGRFAQSGILRDRL IPRVLAAAPDALLDGSGFLDPAAVAACALTDEKPGGHGDRAAAVAALELACWDLNAKLRDEPACVTIARH AGRQPAPAVPVYAAGGYYRPAGGVDALRREMGEYLELGYRAVKMKIGGAALGEDLARVEAVIDVVGDAGR VAVDANGRFGRAEAIRWAGALAGYGLRWFEEPGDPLDYALHRAVTDCYDGPVATGENLFSVPDVTNLVRY GGMRPDHDVFQMDPGLSYGLSEYLRMLDVLADHGFDRGCAFPHGGHLINLHVAAGLGLGGCEAYPGVFAP FGGYPDGCVVSSGMIAPPDAAGFGLEQKPGLAELIAELTGERR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4624 | - | - | 100% (393) | mandelate racemase/muconate lactonizing enzyme |
| M. avium 104 | MAV_3096 | - | 3e-20 | 29.80% (302) | mandelate racemase/muconate lactonizing enzyme |
| M. avium 104 | MAV_4590 | - | 2e-07 | 30.60% (232) | O-succinylbenzoate synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0568 | menC | 1e-06 | 32.43% (185) | O-succinylbenzoate synthase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0553 | menC | 1e-06 | 32.43% (185) | O-succinylbenzoate synthase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0864 | - | 1e-166 | 74.04% (389) | mandelate racemase |
| M. smegmatis MC2 155 | MSMEG_0126 | - | 1e-20 | 34.20% (231) | mandelate racemase/muconate lactonizing enzyme |
| M. thermoresistible (build 8) | TH_0152 | menC | 2e-06 | 31.03% (174) | PROBABLE MUCONATE CYCLOISOMERASE MENC (CIS,CIS-MUCONATE |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0971 | - | 3e-08 | 30.00% (210) | O-succinylbenzoate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0152|M.thermoresistible__bu -----------------VGDTG-------------PVMPTLDELLER---
Mvan_0971|M.vanbaalenii_PYR-1 ---------MGRRPRRRVRSRGRAGACAFRLLRHDEAVPELADVLDR---
Mb0568|M.bovis_AF2122/97 ---------------------------------MIPVLPPLEALLDR---
Rv0553|M.tuberculosis_H37Rv ---------------------------------MIPVLPPLEALLDR---
MAV_4624|M.avium_104 --MRITGIVERAVRLDAPGRGGPANAVVDFSGHTVSLVAVLTDAVRRGRP
MMAR_0864|M.marinum_M --MRIVAILERPVRL----LGGPANAVVNFSQHTVSLVAVVSDVIRHGKP
MSMEG_0126|M.smegmatis_MC2_155 MTDRICRLALSHVVLPLPKPVSDAKVLTGRQKPLTETVLLFVEVSTSDGL
: .
TH_0152|M.thermoresistible__bu ------------LRVVALPMRVPFRGVTVREVALIEG-------------
Mvan_0971|M.vanbaalenii_PYR-1 ------------LHVVALPMRVRFRGITTRELALIDG-------------
Mb0568|M.bovis_AF2122/97 ------------LYVVALPMRVRFRGITTREVALIEG-------------
Rv0553|M.tuberculosis_H37Rv ------------LYVVALPMRVRFRGITTREVALIEG-------------
MAV_4624|M.avium_104 VAGVAFDSIGRFAQSGILRDRLIPRVLAAAPDALLDGSGFLDPAAVAACA
MMAR_0864|M.marinum_M LTGVAFNSIGRFAQSGILRDRMIPRVLAAPEDALLDQRGHLDPAAVLRHA
MSMEG_0126|M.smegmatis_MC2_155 QG-------MGFSYSKRAGGPAQYTHLHEIAEVALGQDPSDIDRIYQSLL
: . :
TH_0152|M.thermoresistible__bu -----PVAWGEFG---AFPEYGPAEAAAWLAAGIEAAFKSPPLIRRHR--
Mvan_0971|M.vanbaalenii_PYR-1 -----PAGWGEFG---AFVEYRPAEAAHWLAAGIEAAYRPLPEVRRPR--
Mb0568|M.bovis_AF2122/97 -----PAGWGEFG---AFVEYQSAQACAWLASAIETAYCAPPPVRRDR--
Rv0553|M.tuberculosis_H37Rv -----PAGWGEFG---AFVEYQSAQACAWLASAIETAYCAPPPVRRDR--
MAV_4624|M.avium_104 LTDEKPGGHGDRAAAVAALELACWDLNAKLRDEPACVTIARHAGRQPAPA
MMAR_0864|M.marinum_M VCDEKPGGHGDRAGAAAAVELACWDLAAKLNDEPAYATIARHFGRDPAPL
MSMEG_0126|M.smegmatis_MC2_155 WAGASVGRSGVATQAIAALDVALWDLKARRAGLPLAKLIG--AQRDSCRV
* * : : *
TH_0152|M.thermoresistible__bu IPINAT----VPAVPAQRVPEVLSRFPGARTAKVKVAEPGQTLTDDVARV
Mvan_0971|M.vanbaalenii_PYR-1 IPINAT----VPAVAAHDVPGVLARFPGVRTAKVKVAEPGQTLADDVARV
Mb0568|M.bovis_AF2122/97 VPINAT----VPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERV
Rv0553|M.tuberculosis_H37Rv VPINAT----VPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERV
MAV_4624|M.avium_104 VPVYAAGGYYRPAGGVDALRREMGEYLELGYRAVKMKIGGAALGEDLARV
MMAR_0864|M.marinum_M VSVYAAGGYYYPGGGLNALRDEMRRYLDLGYDAVKMKIGGVAQRDDLARI
MSMEG_0126|M.smegmatis_MC2_155 YNTSGG----FLQASLDEVKDAATASLESGIGGVKIKVGQPDWAEDLKRV
. : **: :*: *:
TH_0152|M.thermoresistible__bu NAVRELVP---TVRVDVNGAWTVDEAVKAAAALTADGPLEYLEQP--CAT
Mvan_0971|M.vanbaalenii_PYR-1 NAVRDAVP---TVRVDANGGWTVDEAVAAARALTADGPLEYLEQP--CRT
Mb0568|M.bovis_AF2122/97 NAVRELVP---MVRVDANGGWGVAEAVAAAAALTADGPLEYLEQP--CAT
Rv0553|M.tuberculosis_H37Rv NAVRELVP---MVRVDANGGWGVAEAVAAAAALTADGPLEYLEQP--CAT
MAV_4624|M.avium_104 EAVIDVVGDAGRVAVDANGRFGRAEAIRWAGALAGYG-LRWFEEPGDPLD
MMAR_0864|M.marinum_M EAVIDVVG-ADRVAVDANGRFDRAAATRWAATLAPYG-LRWYEEPGDPLD
MSMEG_0126|M.smegmatis_MC2_155 AAMRAHLG-DTPLMVDANQQWDRARARRMCRELEQFD-LVWIEEPLDAWD
*: : : **.* : * . * . * : *:*
TH_0152|M.thermoresistible__bu IAELAELRRRIDVPIAADESIRKADDPLRVVRAGAADIAVLKVAPLGGAY
Mvan_0971|M.vanbaalenii_PYR-1 VPELAEVRRRVDVPVAADESIRKAEDPLHVVRSGAADVAVLKVAPLGGVH
Mb0568|M.bovis_AF2122/97 VAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGIS
Rv0553|M.tuberculosis_H37Rv VAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGIS
MAV_4624|M.avium_104 YALHRAVTDCYDGPVATGENLFSVPDVTNLVRYGGMRPDHDVFQMDPGLS
MMAR_0864|M.marinum_M FELNRAVTGCYAGTVATGENLFSVPDVTNLVRYGGMRAGRDIFQMDAGLS
MSMEG_0126|M.smegmatis_MC2_155 AVGHADLSHTFDTPIATGEMLTSVPEHMALIDAG----YRGIVQPDAPRI
: .:*:.* : .. : :: .
TH_0152|M.thermoresistible__bu RLLEIATAIDIPIVVSSALDTAVGIGRGLLAAAALPQLNHACGLGTGRLF
Mvan_0971|M.vanbaalenii_PYR-1 AMLDIAAQIDIPVVVSSALDSAVGIGVGLVAAGSLPTLDHACGLGTGGLF
Mb0568|M.bovis_AF2122/97 ALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLF
Rv0553|M.tuberculosis_H37Rv ALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLF
MAV_4624|M.avium_104 YGLSEYLRM-LDVLADHGFDRGCAFPHG----GHLINLHVAAGLGLGG--
MMAR_0864|M.marinum_M YGLGEYVRM-LELIEAHGFDRRCAYPHG----GHMINLHIAAGLGLGG--
MSMEG_0126|M.smegmatis_MC2_155 GGITPFLRF-ATLASHAGLALAPHYAME-------IHLHLAATYPTEP-W
: : : .: *. *.
TH_0152|M.thermoresistible__bu VEDVAEPLELVDGHLPAAPVRPDPQRVLELAAPPDRRRWWMDRTRECFAL
Mvan_0971|M.vanbaalenii_PYR-1 VDDVAAPVVPVDGYLPAAPVTPDLDRIAALAAPPDRRQWWIARVRECFPL
Mb0568|M.bovis_AF2122/97 EEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSL
Rv0553|M.tuberculosis_H37Rv EEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSL
MAV_4624|M.avium_104 CEAYPGVFAPFGGYPDGCVVSS------GMIAPPDAAGFGLEQKPGLAEL
MMAR_0864|M.marinum_M CESYPGVFQPFGGYCDGCVLRD------GQIVPTDAPGFGLERKPGLGEL
MSMEG_0126|M.smegmatis_MC2_155 VEHFEWLNPLFN---ERIEIRD------GRMWLPDRPGLGFTLSDQMRAL
: .. .: : *
TH_0152|M.thermoresistible__bu LET------
Mvan_0971|M.vanbaalenii_PYR-1 VS-------
Mb0568|M.bovis_AF2122/97 LVPSFG---
Rv0553|M.tuberculosis_H37Rv LVPSFG---
MAV_4624|M.avium_104 IAELTGERR
MMAR_0864|M.marinum_M ISELTR---
MSMEG_0126|M.smegmatis_MC2_155 TREQAEFQA