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MEDPEAAMMRALYDEHATALWRYALRLTGDPARAEDVVQETLLRAWRHQPDLRTGGGADGIAGPDRSPRA WLFTVARNMIIDERRSARFRNETDVPDPEQVADHATSDQVDTALDRLLLGTALRQLSDDHRAVIRRAYYQ GLTTGQIAAELQIPEGTVKSRLHYAVRALKLSLQEMGVTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1486 | - | - | 100% (180) | RNA polymerase sigma factor SigL |
| M. smegmatis MC2 155 | MSMEG_5214 | - | 3e-42 | 50.85% (177) | RNA polymerase sigma-70 factor |
| M. smegmatis MC2 155 | MSMEG_3485 | - | 1e-12 | 36.26% (171) | putative ECF sigma factor RpoE1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0756 | sigL | 4e-59 | 66.48% (176) | RNA polymerase sigma factor SigL |
| M. gilvum PYR-GCK | Mflv_5019 | - | 1e-74 | 78.89% (180) | RNA polymerase sigma factor SigL |
| M. tuberculosis H37Rv | Rv0735 | sigL | 4e-59 | 66.48% (176) | RNA polymerase sigma factor SigL |
| M. leprae Br4923 | MLBr_01076 | sigE | 6e-12 | 31.29% (163) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_2163 | - | 5e-46 | 57.56% (172) | ECF subfamily RNA polymerase sigma factor |
| M. marinum M | MMAR_1073 | sigL | 3e-56 | 61.93% (176) | alternative RNA polymerase sigma factor (RpoE), SigL |
| M. avium 104 | MAV_4431 | - | 1e-58 | 64.77% (176) | RNA polymerase sigma factor SigL |
| M. thermoresistible (build 8) | TH_0545 | sigE | 3e-12 | 30.86% (162) | ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGE |
| M. ulcerans Agy99 | MUL_0831 | sigL | 4e-55 | 60.80% (176) | RNA polymerase sigma factor SigL |
| M. vanbaalenii PYR-1 | Mvan_1350 | - | 1e-72 | 77.22% (180) | RNA polymerase sigma factor SigL |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0756|M.bovis_AF2122/97 --------------------------------------------------
Rv0735|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4431|M.avium_104 --------------------------------------------------
MMAR_1073|M.marinum_M --------------------------------------------------
MUL_0831|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5019|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1350|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1486|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2163|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
TH_0545|M.thermoresistible__bu ---------------------------------------------MSVPA
Mb0756|M.bovis_AF2122/97 ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
Rv0735|M.tuberculosis_H37Rv ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
MAV_4431|M.avium_104 ----------------------MVGISRASGTAEAALMKALYDEHAAVLW
MMAR_1073|M.marinum_M ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
MUL_0831|M.ulcerans_Agy99 ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
Mflv_5019|M.gilvum_PYR-GCK ----------------------ME-------DADAAMMRVLYDEHAAALW
Mvan_1350|M.vanbaalenii_PYR-1 ----------------------MD-------DPEAAMMRVLYDEHAAALW
MSMEG_1486|M.smegmatis_MC2_155 ----------------------ME-------DPEAAMMRALYDEHATALW
MAB_2163|M.abscessus_ATCC_1997 -------------------------------------MRAFYDEYAGPLH
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
TH_0545|M.thermoresistible__bu SMTHFAPPQATEWAEPVEEPTGTAVFDATGDKSTMPSWDELVRQHADRVY
: ::* :
Mb0756|M.bovis_AF2122/97 RYALRLTGDAAQAEDVVQETLLRAWQHP---------EVIGDTARPARAW
Rv0735|M.tuberculosis_H37Rv RYALRLTGDAAQAEDVVQETLLRAWQHP---------EVIGDTARPARAW
MAV_4431|M.avium_104 RYALRLTGDASQSEDVVQETLLRAWQHP---------EVIGDTERSARAW
MMAR_1073|M.marinum_M RYAMRLTSDASYADDIVQETLLRAWQHP---------EVIDERGRSARAW
MUL_0831|M.ulcerans_Agy99 RYTMRLTSDASYADDIVQETLLRAWQHP---------EVIDERGRSARAW
Mflv_5019|M.gilvum_PYR-GCK RYALRLTGDRARSEDVVQETLLRAWRHP---------GVIADVDRPARAW
Mvan_1350|M.vanbaalenii_PYR-1 RYALRLTGDRARAEDVVQETLLRAWRHP---------EVTADVDRSARAW
MSMEG_1486|M.smegmatis_MC2_155 RYALRLTGDPARAEDVVQETLLRAWRHQPDLRTGGGADGIAGPDRSPRAW
MAB_2163|M.abscessus_ATCC_1997 RYVMHLTHDSALAEDIVQEVLLRAWRHP---------TLVNQTEGSARAW
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSV-----------QNYQPGTFEGW
TH_0545|M.thermoresistible__bu RLAYRLSGNQHDAEDLTQETFIRVFRSL-----------QNYQPGTFEGW
. :*: : ::*:.**.::*.:: . ..*
Mb0756|M.bovis_AF2122/97 LFTVARNMIIDERRS-ARFRNVVGSTDQSGTPEQSTPDE--VNAALDRLL
Rv0735|M.tuberculosis_H37Rv LFTVARNMIIDERRS-ARFRNVVGSTDQSGTPEQSTPDE--VNAALDRLL
MAV_4431|M.avium_104 LFTVARNMIIDDRRS-ARFRNVVGSTDTAGAPEQSTPDE--VNAALDRLL
MMAR_1073|M.marinum_M LFTVARNMIIDDRRS-ARYRYVVSSTDADGAPEQSTPDE--VGAALDRLL
MUL_0831|M.ulcerans_Agy99 LFTVARNMIIDDRRS-ARYRYVVSSTDADGAPEQSTPDE--VGAALGRLL
Mflv_5019|M.gilvum_PYR-GCK LFTVARNMIIDERRS-ARFRHETGVPDPEHVAEPASPDE--ADPTLDRIL
Mvan_1350|M.vanbaalenii_PYR-1 LFTVARNMIIDERRS-ARFKHESGVADTEYVPDSASPDE--ADTALDRIL
MSMEG_1486|M.smegmatis_MC2_155 LFTVARNMIIDERRS-ARFRNETDVPDPEQVADHATSDQ--VDTALDRLL
MAB_2163|M.abscessus_ATCC_1997 LFTVAHNLVRDNARS-SRFRSEIATAET---PEFASPDQ--VDATLDAWL
MLBr_01076|M.leprae_Br4923 LHRITTNLFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPD
TH_0545|M.thermoresistible__bu LHRITTNLFLDMVRRRGRIRMESLPEDYDRVPGNSPNPEQIYHDARLGPD
*. :: *:. * * .* : : . . : :
Mb0756|M.bovis_AF2122/97 IADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRA
Rv0735|M.tuberculosis_H37Rv IADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRA
MAV_4431|M.avium_104 IADAMAQLSAEHRAVIERSYYRGWTTAQIATDLGIAEGTVKSRLHYAVRA
MMAR_1073|M.marinum_M IADALAQLSGEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRA
MUL_0831|M.ulcerans_Agy99 IADALAQLSGEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRA
Mflv_5019|M.gilvum_PYR-GCK LGTALRQLSDEHRAVVRRAYYQGWTTGQIAADLQIPEGTVKSRLHYAVRA
Mvan_1350|M.vanbaalenii_PYR-1 LSTALSQLSDEHRAVVRRAYYQGWTTGQIAADLNIPEGTVKSRLHYAVRA
MSMEG_1486|M.smegmatis_MC2_155 LGTALRQLSDDHRAVIRRAYYQGLTTGQIAAELQIPEGTVKSRLHYAVRA
MAB_2163|M.abscessus_ATCC_1997 VAEALRTLSTDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRA
MLBr_01076|M.leprae_Br4923 LQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
TH_0545|M.thermoresistible__bu LQAALDSLPPDFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
: *: *. :.**.: . .* : :*. * : ***:**:* . :*
Mb0756|M.bovis_AF2122/97 LRLTLQELGVTR------------
Rv0735|M.tuberculosis_H37Rv LRLTLQELGVTR------------
MAV_4431|M.avium_104 LRLTLQELGVTR------------
MMAR_1073|M.marinum_M LRLTLQELGVTR------------
MUL_0831|M.ulcerans_Agy99 LRLTLQELGVTR------------
Mflv_5019|M.gilvum_PYR-GCK LKLGLQEMGVTR------------
Mvan_1350|M.vanbaalenii_PYR-1 LKLGLQEMGVTR------------
MSMEG_1486|M.smegmatis_MC2_155 LKLSLQEMGVTR------------
MAB_2163|M.abscessus_ATCC_1997 LRLSLQEMGVTR------------
MLBr_01076|M.leprae_Br4923 LRDYLLTAHPRDGATTDATHVKSA
TH_0545|M.thermoresistible__bu LRDYLARHSQNSGQSATTS-----
*: *