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MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGDACELSLLESVQLQEFDVVVA ATGDDKANVVLSLLAKTEFAVPRVVARVNDPRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLM EFRKGQANLVEITLPDDTPWGGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDELLFVAVAEAEE ELQKLLLG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3583 | - | - | 100% (218) | TrkB protein |
M. avium 104 | MAV_3582 | - | 6e-13 | 26.79% (209) | TrkA protein |
M. avium 104 | MAV_1443 | - | 4e-07 | 31.78% (107) | TrkA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2711 | ceoC | 1e-111 | 90.78% (217) | TRK system potassium uptake protein CEOC |
M. gilvum PYR-GCK | Mflv_3928 | - | 1e-106 | 86.18% (217) | TrkA domain-containing protein |
M. tuberculosis H37Rv | Rv2692 | ceoC | 1e-110 | 90.32% (217) | TRK system potassium uptake protein CEOC |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2995 | - | 4e-98 | 78.34% (217) | Trk system potassium uptake protein CeoC |
M. marinum M | MMAR_2022 | ceoC | 1e-111 | 92.17% (217) | TRK system potassium uptake protein CeoC |
M. smegmatis MC2 155 | MSMEG_2769 | - | 1e-105 | 84.79% (217) | TrkB protein |
M. thermoresistible (build 8) | TH_2213 | trkB | 1e-101 | 82.49% (217) | TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOC |
M. ulcerans Agy99 | MUL_3330 | ceoC | 1e-111 | 92.17% (217) | TRK system potassium uptake protein CeoC |
M. vanbaalenii PYR-1 | Mvan_2472 | - | 1e-108 | 86.64% (217) | TrkA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MAB_2995|M.abscessus_ATCC_1997 MKVAIGGAGAVGRSIARELIESRHEVTLLERNPDHIDPEAVPEAQWRLGD TH_2213|M.thermoresistible__bu MKVAIAGAGAVGRSIARELLAS-HEVLLVERNPDHFEPDVIPGAEWRLGD Mflv_3928|M.gilvum_PYR-GCK MKVAIAGAGAVGRSIARELVDA-HEVTLLERNAEHIDVNAIPAAHWRLGD Mvan_2472|M.vanbaalenii_PYR-1 MKVAIAGAGAVGRSIARELVES-HDVTLLERNPDHIDVDAVPAAHWRLGD MSMEG_2769|M.smegmatis_MC2_155 MKVAIAGAGAVGRSIARELLESNHEVTLLERNLDHIDVDAIPAAHWRLGD Mb2711|M.bovis_AF2122/97 MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGD Rv2692|M.tuberculosis_H37Rv MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGD MMAR_2022|M.marinum_M MKVVVAGAGAVGRSVARELIANAHDVTLIERNSDHVDDDAIPAAHWLLGD MUL_3330|M.ulcerans_Agy99 MKVVVAGAGAVGRSVARELIANAHDVTLIERNSDHVDDDAIPAAHWLLGD MAV_3583|M.avium_104 MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGD ***.:.********::***: *:: *:*** :*.: .:* *.* *** MAB_2995|M.abscessus_ATCC_1997 ACEISLLEAEELHTFDVVIAATGDDKANLVLSLLAKTEFAVARVVARVND TH_2213|M.thermoresistible__bu ACELSLLESVGLEQYDVVIAATGDDKANVVVSLLAKTEFGVSRVVARVND Mflv_3928|M.gilvum_PYR-GCK ACELSLLESVKLQEFDVVIAATGDDKANVVLSLLSKTEFAVPRVVARVND Mvan_2472|M.vanbaalenii_PYR-1 ACELSLLESVKLEEFDVVIAATGDDKANVVVSLLSKTEFAVPRVVARVND MSMEG_2769|M.smegmatis_MC2_155 ACEITMLESVRLEEFDVVIAATGDDKVNVVVSLLAKTEFAVPRVVARVND Mb2711|M.bovis_AF2122/97 ACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVND Rv2692|M.tuberculosis_H37Rv ACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVND MMAR_2022|M.marinum_M ACELSLLESVHLEDFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND MUL_3330|M.ulcerans_Agy99 ACELSLLESVHLEDFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND MAV_3583|M.avium_104 ACELSLLESVQLQEFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND ***:::**: *. :***:*******.*:*:***:****.*.******** MAB_2995|M.abscessus_ATCC_1997 PRNEWLFDDAWGVDVAVSTPRMLASLVEEAVAVGDVVRLMEFRKGQANLV TH_2213|M.thermoresistible__bu PRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRQGQANLV Mflv_3928|M.gilvum_PYR-GCK PRNEWLFDESWGVDVAVSTPRMLASLVEEAVSVGDLVRLMEFRKGQANLV Mvan_2472|M.vanbaalenii_PYR-1 PRNEWLFDESWGVDVAVSTPRMLASLVEEAVSVGDLVRLMEFRKGQANLV MSMEG_2769|M.smegmatis_MC2_155 PRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRKGQANLV Mb2711|M.bovis_AF2122/97 PRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTVGDLVRLMEFRTGQANLV Rv2692|M.tuberculosis_H37Rv PRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLV MMAR_2022|M.marinum_M PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV MUL_3330|M.ulcerans_Agy99 PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV MAV_3583|M.avium_104 PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV ******* : ****************:****::**:******* ****** MAB_2995|M.abscessus_ATCC_1997 EITLPDDTPWGGKPVRKLELPRDAVLVAILRGSRVIAAQPDEPLEGGDEL TH_2213|M.thermoresistible__bu EITLPDDTPWGGRPVRRLDLPRDAAMVAILRGPRVIVPEPDEPLEGGDEL Mflv_3928|M.gilvum_PYR-GCK EITLPDDTPWGGKPVKRLELPRDATLVTILRGPRVIVPERDEPLEGGDEL Mvan_2472|M.vanbaalenii_PYR-1 EITLPDDTPWGGKPVKRLELPRDATLVTILRGPRVIVPERDEPLEGGDEL MSMEG_2769|M.smegmatis_MC2_155 EITLPDDTPWGGKPVKRLELPRDAALVTILRGARVIVPEADEPLEGGDEL Mb2711|M.bovis_AF2122/97 EITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDEL Rv2692|M.tuberculosis_H37Rv EITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDEL MMAR_2022|M.marinum_M EITLPDDTPWGGKPVRKLQLPRDAVLVTILRGPRVIVPQADEPLEGGDEL MUL_3330|M.ulcerans_Agy99 EITLPDDTPWGGKPVRKLQLPRDAVLVTILRGPRVIVPQADEPLEGGDEL MAV_3583|M.avium_104 EITLPDDTPWGGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDEL ******:*****:**::*:*****.:*:****.***..: ********** MAB_2995|M.abscessus_ATCC_1997 ILVATADIEDELHRAVLPE--- TH_2213|M.thermoresistible__bu LFVAVAEVEDELREIILRPPRQ Mflv_3928|M.gilvum_PYR-GCK LFVTAAEAEDELRTLLLNPQQR Mvan_2472|M.vanbaalenii_PYR-1 LFVAVAESEDELRELVLNPQHR MSMEG_2769|M.smegmatis_MC2_155 LFVATTEVEDELLEVLLRPTRR Mb2711|M.bovis_AF2122/97 LFVAVTEAEEELSRLLLPSM-- Rv2692|M.tuberculosis_H37Rv LFVAVTEAEEELSRLLLPSM-- MMAR_2022|M.marinum_M LFVAVTEAEEELSQLLLPSS-- MUL_3330|M.ulcerans_Agy99 LFVAVTEAEEELSQLLLPSS-- MAV_3583|M.avium_104 LFVAVAEAEEELQKLLLG---- ::*:.:: *:** :*