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KVAIAGAGAVGRSIARELVESHDVTLLERNPDHIDVDAVPAAHWRLGDACELSLLESVKLEEFDVVIAAT GDDKANVVVSLLSKTEFAVPRVVARVNDPRNEWLFDESWGVDVAVSTPRMLASLVEEAVSVGDLVRLMEF RKGQANLVEITLPDDTPWGGKPVKRLELPRDATLVTILRGPRVIVPERDEPLEGGDELLFVAVAESEDEL RELVLNPQHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2472 | - | - | 100% (221) | TrkA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0745 | - | 2e-56 | 48.66% (224) | TrkA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2473 | - | 8e-10 | 22.27% (211) | TrkA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2711 | ceoC | 1e-104 | 83.41% (217) | TRK system potassium uptake protein CEOC |
| M. gilvum PYR-GCK | Mflv_3928 | - | 1e-116 | 93.21% (221) | TrkA domain-containing protein |
| M. tuberculosis H37Rv | Rv2692 | ceoC | 1e-104 | 82.95% (217) | TRK system potassium uptake protein CEOC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2995 | - | 1e-98 | 82.03% (217) | Trk system potassium uptake protein CeoC |
| M. marinum M | MMAR_2022 | ceoC | 1e-104 | 83.87% (217) | TRK system potassium uptake protein CeoC |
| M. avium 104 | MAV_3583 | - | 1e-108 | 86.64% (217) | TrkB protein |
| M. smegmatis MC2 155 | MSMEG_2769 | - | 1e-109 | 88.74% (222) | TrkB protein |
| M. thermoresistible (build 8) | TH_2213 | trkB | 1e-105 | 85.32% (218) | TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOC |
| M. ulcerans Agy99 | MUL_3330 | ceoC | 1e-104 | 83.87% (217) | TRK system potassium uptake protein CeoC |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2472|M.vanbaalenii_PYR-1 MKVAIAGAGAVGRSIARELVES-HDVTLLERNPDHIDVDAVPAAHWRLGD
Mflv_3928|M.gilvum_PYR-GCK MKVAIAGAGAVGRSIARELVDA-HEVTLLERNAEHIDVNAIPAAHWRLGD
MSMEG_2769|M.smegmatis_MC2_155 MKVAIAGAGAVGRSIARELLESNHEVTLLERNLDHIDVDAIPAAHWRLGD
MAB_2995|M.abscessus_ATCC_1997 MKVAIGGAGAVGRSIARELIESRHEVTLLERNPDHIDPEAVPEAQWRLGD
TH_2213|M.thermoresistible__bu MKVAIAGAGAVGRSIARELLAS-HEVLLVERNPDHFEPDVIPGAEWRLGD
Mb2711|M.bovis_AF2122/97 MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGD
Rv2692|M.tuberculosis_H37Rv MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGD
MMAR_2022|M.marinum_M MKVVVAGAGAVGRSVARELIANAHDVTLIERNSDHVDDDAIPAAHWLLGD
MUL_3330|M.ulcerans_Agy99 MKVVVAGAGAVGRSVARELIANAHDVTLIERNSDHVDDDAIPAAHWLLGD
MAV_3583|M.avium_104 MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAHWRLGD
***.:.********::***: *:: *:*** :*.: .:* *.* ***
Mvan_2472|M.vanbaalenii_PYR-1 ACELSLLESVKLEEFDVVIAATGDDKANVVVSLLSKTEFAVPRVVARVND
Mflv_3928|M.gilvum_PYR-GCK ACELSLLESVKLQEFDVVIAATGDDKANVVLSLLSKTEFAVPRVVARVND
MSMEG_2769|M.smegmatis_MC2_155 ACEITMLESVRLEEFDVVIAATGDDKVNVVVSLLAKTEFAVPRVVARVND
MAB_2995|M.abscessus_ATCC_1997 ACEISLLEAEELHTFDVVIAATGDDKANLVLSLLAKTEFAVARVVARVND
TH_2213|M.thermoresistible__bu ACELSLLESVGLEQYDVVIAATGDDKANVVVSLLAKTEFGVSRVVARVND
Mb2711|M.bovis_AF2122/97 ACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVND
Rv2692|M.tuberculosis_H37Rv ACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVND
MMAR_2022|M.marinum_M ACELSLLESVHLEDFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND
MUL_3330|M.ulcerans_Agy99 ACELSLLESVHLEDFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND
MAV_3583|M.avium_104 ACELSLLESVQLQEFDVVVAATGDDKANVVLSLLAKTEFAVPRVVARVND
***:::**: *. :***:*******.*:*:***:****.*.********
Mvan_2472|M.vanbaalenii_PYR-1 PRNEWLFDESWGVDVAVSTPRMLASLVEEAVSVGDLVRLMEFRKGQANLV
Mflv_3928|M.gilvum_PYR-GCK PRNEWLFDESWGVDVAVSTPRMLASLVEEAVSVGDLVRLMEFRKGQANLV
MSMEG_2769|M.smegmatis_MC2_155 PRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRKGQANLV
MAB_2995|M.abscessus_ATCC_1997 PRNEWLFDDAWGVDVAVSTPRMLASLVEEAVAVGDVVRLMEFRKGQANLV
TH_2213|M.thermoresistible__bu PRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRQGQANLV
Mb2711|M.bovis_AF2122/97 PRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTVGDLVRLMEFRTGQANLV
Rv2692|M.tuberculosis_H37Rv PRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLV
MMAR_2022|M.marinum_M PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV
MUL_3330|M.ulcerans_Agy99 PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV
MAV_3583|M.avium_104 PRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEFRKGQANLV
******* : ****************:****::**:******* ******
Mvan_2472|M.vanbaalenii_PYR-1 EITLPDDTPWGGKPVKRLELPRDATLVTILRGPRVIVPERDEPLEGGDEL
Mflv_3928|M.gilvum_PYR-GCK EITLPDDTPWGGKPVKRLELPRDATLVTILRGPRVIVPERDEPLEGGDEL
MSMEG_2769|M.smegmatis_MC2_155 EITLPDDTPWGGKPVKRLELPRDAALVTILRGARVIVPEADEPLEGGDEL
MAB_2995|M.abscessus_ATCC_1997 EITLPDDTPWGGKPVRKLELPRDAVLVAILRGSRVIAAQPDEPLEGGDEL
TH_2213|M.thermoresistible__bu EITLPDDTPWGGRPVRRLDLPRDAAMVAILRGPRVIVPEPDEPLEGGDEL
Mb2711|M.bovis_AF2122/97 EITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDEL
Rv2692|M.tuberculosis_H37Rv EITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDEL
MMAR_2022|M.marinum_M EITLPDDTPWGGKPVRKLQLPRDAVLVTILRGPRVIVPQADEPLEGGDEL
MUL_3330|M.ulcerans_Agy99 EITLPDDTPWGGKPVRKLQLPRDAVLVTILRGPRVIVPQADEPLEGGDEL
MAV_3583|M.avium_104 EITLPDDTPWGGKPVRRLQLPRDAALVTILRGPRVIVPEEDEPLEGGDEL
******:*****:**::*:*****.:*:****.***..: **********
Mvan_2472|M.vanbaalenii_PYR-1 LFVAVAESEDELRELVLNPQHR
Mflv_3928|M.gilvum_PYR-GCK LFVTAAEAEDELRTLLLNPQQR
MSMEG_2769|M.smegmatis_MC2_155 LFVATTEVEDELLEVLLRPTRR
MAB_2995|M.abscessus_ATCC_1997 ILVATADIEDELHRAVLPE---
TH_2213|M.thermoresistible__bu LFVAVAEVEDELREIILRPPRQ
Mb2711|M.bovis_AF2122/97 LFVAVTEAEEELSRLLLPSM--
Rv2692|M.tuberculosis_H37Rv LFVAVTEAEEELSRLLLPSM--
MMAR_2022|M.marinum_M LFVAVTEAEEELSQLLLPSS--
MUL_3330|M.ulcerans_Agy99 LFVAVTEAEEELSQLLLPSS--
MAV_3583|M.avium_104 LFVAVAEAEEELQKLLLG----
::*:.:: *:** :*