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VVMGCGRVGSSVADGLSRIGHDVAVIDRDSTAFNRLSPEYAGERVLGQGFDRDVLLRAGIEEADAFAAVS SGDNSNIISARLARETFGVKRVVARIYDAKRAEVYERLGIPTIATVPWTTDRLLNALLRETQTAKWRDPT GTVAVSEVVLHEDWIGHRVTDLEQATGARVAFLIRFGSGVLPEPKSVIQAGDQVYVAAISGRAAEAAAIA ALPPSEDL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3582 | - | - | 100% (218) | TrkA protein |
| M. avium 104 | MAV_3583 | - | 6e-13 | 26.79% (209) | TrkB protein |
| M. avium 104 | MAV_1443 | - | 4e-08 | 26.98% (215) | TrkA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2710 | ceoB | 1e-112 | 89.86% (217) | TRK system potassium uptake protein CEOB |
| M. gilvum PYR-GCK | Mflv_3927 | - | 3e-97 | 77.88% (217) | TrkA domain-containing protein |
| M. tuberculosis H37Rv | Rv2691 | ceoB | 1e-111 | 89.40% (217) | TRK system potassium uptake protein CEOB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2994 | - | 3e-95 | 76.50% (217) | Trk system potassium uptake protein CeoB |
| M. marinum M | MMAR_2023 | ceoB | 1e-110 | 91.71% (217) | TRK system potassium uptake protein CeoB |
| M. smegmatis MC2 155 | MSMEG_2771 | - | 2e-97 | 77.52% (218) | TrkA protein |
| M. thermoresistible (build 8) | TH_2212 | trkA | 6e-92 | 77.51% (209) | TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOB |
| M. ulcerans Agy99 | MUL_3329 | ceoB | 1e-110 | 91.71% (217) | TRK system potassium uptake protein CeoB |
| M. vanbaalenii PYR-1 | Mvan_2473 | - | 2e-98 | 78.80% (217) | TrkA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3927|M.gilvum_PYR-GCK MQRPWPGKDPQVRVVVMGCGRVGASLSDSLSRIGHDVAVIDRDGTAFHRL
Mvan_2473|M.vanbaalenii_PYR-1 -----------MRVVVMGCGRVGASLSDSLARIGHDVAVIDRDGTAFHRL
TH_2212|M.thermoresistible__bu ---------------------VGAMLSDSLSRIGHDVAVIDRDSTAFHRL
MSMEG_2771|M.smegmatis_MC2_155 -----------MRVVVMGCGRVGASLADSLARIGHEIAVIDRDATAFHRL
MAB_2994|M.abscessus_ATCC_1997 -----------MRVVVMGCGRVGAALAGGLARIGHEVAIIDKEAAAFNRL
MMAR_2023|M.marinum_M -----------MRVVVMGCGRVGSSVADALSRIGHDVSVIDRDGTAFNRL
MUL_3329|M.ulcerans_Agy99 -----------MRVVVMGCGRVGSSVADALSRIGHDVSVIDRDGTAFNRL
MAV_3582|M.avium_104 --------------MVMGCGRVGSSVADGLSRIGHDVAVIDRDSTAFNRL
Mb2710|M.bovis_AF2122/97 -----------MRVVVMGCGRVGASVADGLSRIGHEVAIIDRDSAAFNRL
Rv2691|M.tuberculosis_H37Rv -----------MRVVVMGCGRVGASVADGLSRIGHEVAIIDRDSAAFNRL
**: ::..*:****::::**::.:**:**
Mflv_3927|M.gilvum_PYR-GCK SPDFSGERVLGMGFDRDVLVRAGIENASAFAAVSSGDNSNIISARVARET
Mvan_2473|M.vanbaalenii_PYR-1 SPDFPGERVLGMGFDRDVLIRAGIEQASAFAAVSSGDNSNIISARVARET
TH_2212|M.thermoresistible__bu SPDFSGERIVGMGFDRDVLLRAGIEEAGAFAAVSSGDNSNIISARVARET
MSMEG_2771|M.smegmatis_MC2_155 SPDFPGERILGMGFDRDVLVRAGIEEAGAFAAVSSGDNSNIIAARVARET
MAB_2994|M.abscessus_ATCC_1997 GPEFTGERIVGMGFDRDVLLRAGIERAQAFAAVSSGDNSNIISARAARET
MMAR_2023|M.marinum_M SAEFAGERVLGQGFDRDVLLSAGIEGADAFAAVSSGDNSNIISARLARET
MUL_3329|M.ulcerans_Agy99 SAEFAGERVLGQGFDRDVLLSAGIEGADAFAAVSSGDNSNIISARLARET
MAV_3582|M.avium_104 SPEYAGERVLGQGFDRDVLLRAGIEEADAFAAVSSGDNSNIISARLARET
Mb2710|M.bovis_AF2122/97 SPQFAGERVLGQGFDRDVLLRAGIQGADAFAAVSSGDNSNIISARLARET
Rv2691|M.tuberculosis_H37Rv SPQFAGERVLGQGFDRDVLLRAGIQGADAFAAVSSGDNSNIISARLARET
..::.***::* *******: ***: * **************:** ****
Mflv_3927|M.gilvum_PYR-GCK FGVQRVVARIYDAKRAAVYERLGIPTVATVPWTTDRLLNVLTRETETTKW
Mvan_2473|M.vanbaalenii_PYR-1 FGVQRVVARIYDAKRAAVYERLGIPTVATVPWTTDRLLNALTRETETTKW
TH_2212|M.thermoresistible__bu FGVPRVVARIYDAKRAAVYERLGIPTVATVPWTTDRLLNILVQETETALW
MSMEG_2771|M.smegmatis_MC2_155 FGVQRVVARIYDAKRAAVYERLGIPTVATVPWTTDRLLNVLTRETETTKW
MAB_2994|M.abscessus_ATCC_1997 FGVERVVARIYDAKRAAVYERLGIPTVATVPWTTDRLLHALTRESDTTKW
MMAR_2023|M.marinum_M FGVKRVVARIYDAKRAEVYERLGIPTIATVPWTTDRLLNALLRETETAKW
MUL_3329|M.ulcerans_Agy99 FGVKRVVARIYDAKRAEVYERLGIPTIATVPWTTDRLLNALLRETETAKW
MAV_3582|M.avium_104 FGVKRVVARIYDAKRAEVYERLGIPTIATVPWTTDRLLNALLRETQTAKW
Mb2710|M.bovis_AF2122/97 FGVPRVVARIYDAKRAEVYERLGIPTIATVPWTTDRLLNALMQDTETAKW
Rv2691|M.tuberculosis_H37Rv FGVPRVVARIYDAKRAEVYERLGIPTITTVPWTTDRLLNALMQDTETAKW
*** ************ *********::**********: * ::::*: *
Mflv_3927|M.gilvum_PYR-GCK RDPSGNVGVMELALHEAWVGRRISELESATSGRVSFMIRFGAGLLPEAKT
Mvan_2473|M.vanbaalenii_PYR-1 RDPTGNVGVAELALHEEWVGRRLSELEAATAGRVAFIIRFGAGLLPDAKT
TH_2212|M.thermoresistible__bu RDPTGNVGVTELSLHEQWVGRPVADLEAATGGRVAFMIRFGSGLLPDGRT
MSMEG_2771|M.smegmatis_MC2_155 RDPTGSVGVAELDLHEGWAGRKVTDLEAATGGRVAFMIRFGNGYLPDAKT
MAB_2994|M.abscessus_ATCC_1997 RDPSGSVVVTELALHEDWIGKRVTALEAATGARAAFIIRFGTGVLPDAKT
MMAR_2023|M.marinum_M RDPTGTVAVCEVVLHEDWVGCRVSDLQQATGARVAFLLRFGTGVLPEPKT
MUL_3329|M.ulcerans_Agy99 RDPTGTVAVCEVVLHEDWVGCRVSDLQQATGARVAFLLRFGTGVLPEPKT
MAV_3582|M.avium_104 RDPTGTVAVSEVVLHEDWIGHRVTDLEQATGARVAFLIRFGSGVLPEPKS
Mb2710|M.bovis_AF2122/97 RDPTGTVAVAEVVLHEDWVGHRATDLEQATGARIAFLIRFGTGVLPEPKT
Rv2691|M.tuberculosis_H37Rv RDPTGTVAVAEVVLHEDWVGHRATDLEQATGARIAFLIRFGTGVLPEPKT
***:*.* * *: *** * * : *: **..* :*::*** * **: ::
Mflv_3927|M.gilvum_PYR-GCK VIQAGDQVYLAAVSGHIAEALAIAALPPGEDAEG------
Mvan_2473|M.vanbaalenii_PYR-1 VIQAGDQVYLAAISGHIAEAMAIAGLPPSEDAEG------
TH_2212|M.thermoresistible__bu VIQASDQVYLAAVSGRIAEALAIAALPPADSEEG------
MSMEG_2771|M.smegmatis_MC2_155 VIQSGDQVYLAAVSGHIAEALAIALLPPSDDLDSE-----
MAB_2994|M.abscessus_ATCC_1997 VIQDSDEVYVSAVSGRAAEAMAIAAQPPGEDADDDHGGAR
MMAR_2023|M.marinum_M VLQAGDQVYVAAISGRAAEAVAIAALPPSEDFESGTAK--
MUL_3329|M.ulcerans_Agy99 VLQAGDQVYVAAISGRAAEAVAIAALPPSEDFESGTAK--
MAV_3582|M.avium_104 VIQAGDQVYVAAISGRAAEAAAIAALPPSEDL--------
Mb2710|M.bovis_AF2122/97 VLQAGDKVYIAAISGRAAEAAAIAALPPSEDFESGARR--
Rv2691|M.tuberculosis_H37Rv VLQAGDKVYIAAISGRAAEAAAIAALPPSEDFESGARR--
*:* .*:**::*:**: *** *** **.:.