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MVWPSSHGRTDHHKRSHYATIAGMAARPSPQTERVVNLFELLAADGSAGITLAEASRRLHVHKASCHSML SELLRAGWLLRDPVRKTYHLGPALVRLGREAAARYPALVLARSVMDELAAATGAHCVAFSVSEDYSTVVD QVRSRRGGGHPMPIGTQFPHRPPYGASTVAWAGTEDRERWLAALPDEVRDRYREAIAAARQRGYAVGLHL LPDLRLQELALLVRSAEVRSTRLSQLAQALTDELIHQEEWFPISLAPDRSYEVSHIDSPILGPGPSIALM LSLVPSAEPMSGAAVTRLGTQLAAATRRLSEALTESG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3545 | - | - | 100% (317) | hypothetical protein MAV_3545 |
| M. avium 104 | MAV_5235 | - | 3e-19 | 27.27% (297) | putative transcriptional regulator |
| M. avium 104 | MAV_5001 | - | 4e-15 | 29.28% (222) | hypothetical protein MAV_5001 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1528 | - | 3e-21 | 29.08% (251) | regulatory protein, IclR |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4180 | - | 1e-22 | 28.14% (295) | IclR family transcriptional regulator |
| M. marinum M | MMAR_3507 | - | 2e-19 | 28.77% (292) | IclR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5933 | - | 6e-16 | 30.98% (255) | hypothetical protein MSMEG_5933 |
| M. thermoresistible (build 8) | TH_4062 | - | 8e-38 | 36.63% (303) | PUTATIVE transcriptional regulator PadR family protein |
| M. ulcerans Agy99 | MUL_2762 | - | 2e-19 | 28.77% (292) | IclR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5230 | - | 4e-20 | 28.69% (251) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1528|M.gilvum_PYR-GCK ---------------------------MSVPVQ--PGRASPPTDRVVQIL
Mvan_5230|M.vanbaalenii_PYR-1 ---------------------------MSEPPA--PGRASPPTDRVVRVL
MSMEG_5933|M.smegmatis_MC2_155 ---------------------------MLEQTD--AGRASPPTARVVAIL
MAB_4180|M.abscessus_ATCC_1997 ---------------------------MIEDRDNGAGRTSPPTERVMAVL
MAV_3545|M.avium_104 -----------MVWPSSHGRTDHHKRSHYATIAGMAARPSPQTERVVNLF
TH_4062|M.thermoresistible__bu -----------------------------------MARPSPQTERIVSLV
MMAR_3507|M.marinum_M ------------------------MTDTVDPASVSSQGSSPPTERVIAVL
MUL_2762|M.ulcerans_Agy99 MPSPPALASVEISTYRSIDIPFDILTGTVDPASVSSQGLSPPTERVIAVL
** * *:: :.
Mflv_1528|M.gilvum_PYR-GCK DFLASRPTERYGVSDLARRVGLSKPTCLGIVTSLTEAGYLVR--DPADKT
Mvan_5230|M.vanbaalenii_PYR-1 DFLARHPQERFGVSELARRVDLTKPTCLGIVTSLRDAGYLVR--DPADKT
MSMEG_5933|M.smegmatis_MC2_155 DFLARHPHDRFGLSELSRRVGVSKPTCLGILTTLTESGYLVREGDGRDKC
MAB_4180|M.abscessus_ATCC_1997 DFLAQHRTERFGLSELARRLGLSKPTCLGIVTTLAESGFLIR--DDRDKT
MAV_3545|M.avium_104 ELLAADGSAGITLAEASRRLHVHKASCHSMLSELLRAGWLLR--DPVRKT
TH_4062|M.thermoresistible__bu ELLRSQPRTGRSLADIARHLGVAKATCYPMVVALTEAGWLVR--HPTRKT
MMAR_3507|M.marinum_M ELLGHNSAKQFSLAEICRGLGISRATGHAILTTLAAREWVIR--DPETFR
MUL_2762|M.ulcerans_Agy99 ELLGHNSAKQFSLAEICRGLGISRATGHAILTTLAAREWVIR--DPETFR
::* ::: .* : : :.: :: * :::* .
Mflv_1528|M.gilvum_PYR-GCK YRLGPSLITLGHRAQESMRVSPAARDHLRRLSARYGATAALSAVVDDRIT
Mvan_5230|M.vanbaalenii_PYR-1 YRLGPSLITLGHKAQESMRVSPAAREQLRRLSTRFGATAALSAVVDDRIT
MSMEG_5933|M.smegmatis_MC2_155 YRLGPALIALGHMAQESMRVNPFARAELRALSGAFDSTAAISAVIDDRIT
MAB_4180|M.abscessus_ATCC_1997 YSLGPALIRIGRAAQESLRAKPASRDQLLALTREFGHTAALSAVVSDRVT
MAV_3545|M.avium_104 YHLGPALVRLGREAAARYPALVLARSVMDELAAATGAHCVAFSVSEDYST
TH_4062|M.thermoresistible__bu YQLGPALVPIGAAAAAALDVLDLARPGMQELADTADMACVAFVPSGADLV
MMAR_3507|M.marinum_M YSWGPAIAGLDTPTTA-----QLHRGDLQELAAATGTQVMLARREDATLV
MUL_2762|M.ulcerans_Agy99 YSWGPAIAGLDTPTTA-----QLHRGDLQELAAATGTQVMLARREDATLV
* **:: :. : * : *: . .
Mflv_1528|M.gilvum_PYR-GCK LLDLVAPTGAR---PGVEVGQSYPFAPPVGLMFVLWD-DEAEQDWLRRQP
Mvan_5230|M.vanbaalenii_PYR-1 LLDLVAPVGAR---PGVEVGQSYPFAPPVGLMFVLWD-DEAVRDWLAMEP
MSMEG_5933|M.smegmatis_MC2_155 VLELVAPPGTD---VGVRVGQSYPFAPPVGLMYVLWD-DDALRAWLDKSP
MAB_4180|M.abscessus_ATCC_1997 VLEVVSDPDHP---VRVEVGQSYPFTPPVGLMFVLWDTDETITSWLAKDP
MAV_3545|M.avium_104 VVDQVRSRRG--GGHPMPIGTQFPHRPPYGASTVAWAGTEDRERWLAA--
TH_4062|M.thermoresistible__bu VSEIVQPAGGRRGTLGLRLGDRVQIIPPLGSVVAAWFSEDARWQWYRAGA
MMAR_3507|M.marinum_M VIDTVGECPR---GPRISRGMRTPFVAPIGRDYVAWWSPDAQQDWLRAFG
MUL_2762|M.ulcerans_Agy99 VIDTVGECPR---GPRISRGMRTPFVAPIGRDYVAWWSPDAQQDWLRAFG
: : * : * .* * . * : *
Mflv_1528|M.gilvum_PYR-GCK TIPLR---TDTERLKRVVASCRADGYLVERQTPGGRRLYALMAGMPTELP
Mvan_5230|M.vanbaalenii_PYR-1 TVPLHPSRTDPDRLHRVIRRCRADGYLVERLTPGGRRLYSLMAGMSSTLP
MSMEG_5933|M.smegmatis_MC2_155 TVPLR---TDSERLEKVIGECRNSGYLVERLTPAGQRLYGLMAGMSSRLP
MAB_4180|M.abscessus_ATCC_1997 TAPGR---TADDRLRKVIEECRADGYLVELLTPAGRQLYSLMAGVPGDIP
MAV_3545|M.avium_104 -----LPDEVRDRYREAIAAARQRGYAVGLHLLPDLRLQELALLVRSAEV
TH_4062|M.thermoresistible__bu EEFGVDPDAVEAAYGPVLELVRKRGFAVECLDQQERRLADAVAEVRGDGG
MMAR_3507|M.marinum_M ----APNPRFLQRMTLVLNQIQRRGFVVERLTRQYVRVYTALRALSADG-
MUL_2762|M.ulcerans_Agy99 ----APNPRFLQRMILVLNQIQRRGFVVERLTRQYVRVYTALRALSADG-
.: : *: * :: :
Mflv_1528|M.gilvum_PYR-GCK DELRALLGELVSDIGERVYLREE-----SSGRRKHDISVISAPVFDHYQ-
Mvan_5230|M.vanbaalenii_PYR-1 DELRALLGELVSDIGERVYLPDE-----KPGRKRHDISVISAPVFDHYG-
MSMEG_5933|M.smegmatis_MC2_155 DELQALLRELVSDIGERVHLRSE-----ATGRQRHDVSVISAPVHDHHQ-
MAB_4180|M.abscessus_ATCC_1997 NELRALLGEIVSGIGERVYLRSENYTVGSGAKVRHRVNVISAPVYDHNG-
MAV_3545|M.avium_104 RSTRLSQLAQALTDELIHQEEWFP--ISLAPDRSYEVSHIDSPILGPGPS
TH_4062|M.thermoresistible__bu PLGRGRQTVTLRTVAGRPTVDVLI--GEIEPKRRYQPISINAAVFTAEAV
MMAR_3507|M.marinum_M -EVDEITTQLARAYADLAIIDVLD--EELTSGATHSVATISAPIRGPDG-
MUL_2762|M.ulcerans_Agy99 -EVDEITTQLARAYADLAIIDVLD--EELTSGATHSVATISAPIRGPDG-
: *.:.:
Mflv_1528|M.gilvum_PYR-GCK RQVMVTSMHIGKALTDNEISERARAVVAAADAVTAQLGGMRP--------
Mvan_5230|M.vanbaalenii_PYR-1 RQVMVASMHIGKALTDNEIRERAKALIGTADAVTAQLGGARPTSWPHTVG
MSMEG_5933|M.smegmatis_MC2_155 RQVMVVSLHVGRALTDSEITKRARGVVAAADAVTAQLGGVKPTR------
MAB_4180|M.abscessus_ATCC_1997 KQAMVASLYIADDLTDAEITTRAKALVGTADGITEHIGGTKPF-------
MAV_3545|M.avium_104 IALMLSLVPSAEPMSGAAVTRLGTQLAAATRRLSEALTESG---------
TH_4062|M.thermoresistible__bu PALVLCLVDAPEPLTGRRVDDLGRRVASVAGRLTETLHGRVPDDRRVLRP
MMAR_3507|M.marinum_M SATMTVMATVFANLDGAGIRKLGERLRRSAHAIEQRSARSSA--------
MUL_2762|M.ulcerans_Agy99 SATMTVMATVFANLDGAGIRKLGERLRRSAHAIEQRSARSSA--------
: : . : . : : :
Mflv_1528|M.gilvum_PYR-GCK RDPD---
Mvan_5230|M.vanbaalenii_PYR-1 KGPDRDH
MSMEG_5933|M.smegmatis_MC2_155 -------
MAB_4180|M.abscessus_ATCC_1997 -------
MAV_3545|M.avium_104 -------
TH_4062|M.thermoresistible__bu ESR----
MMAR_3507|M.marinum_M -------
MUL_2762|M.ulcerans_Agy99 -------