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VMAHRLETQGSLLTESWVQAGRLLLRWRRDQAVLMGSLLLPVFLLFCYQIVLGEQVHRVTGAQSVYGVVP MCAVISALFGSLGNSVGITMDRQSRLLSRMWVLPIHRASAITGWVMAEVVRALIGTTLITVIGLAMGLRF SQGWPAALLFLLVPSIVVTGFTALVMAMAIRNNGRAAMTWLLGITFALVFVNPGATPIKLFPHWAQPLIR MQPVSPPIETMRALAHGGPIAWPLEITVAWAVVLVAVFIPVAVRGYRLAAEASG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3252 | - | - | 100% (264) | daunorubicin resistance protein C |
| M. avium 104 | MAV_2004 | - | 1e-68 | 49.19% (248) | ABC-2 type transporter |
| M. avium 104 | MAV_3251 | - | 2e-14 | 26.24% (221) | ABC transporter efflux protein, DrrB family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2963 | drrC | 3e-39 | 32.53% (249) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. gilvum PYR-GCK | Mflv_3387 | - | 1e-45 | 36.65% (251) | multidrug ABC transporter inner membrane protein |
| M. tuberculosis H37Rv | Rv2938 | drrC | 3e-39 | 32.53% (249) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. leprae Br4923 | MLBr_02350 | - | 9e-40 | 34.00% (250) | putative antibiotic resistance membrane protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1769 | drrC | 2e-41 | 35.06% (251) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. smegmatis MC2 155 | MSMEG_6510 | - | 8e-13 | 26.27% (236) | ABC-type drug export system, membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2012 | drrC | 2e-41 | 35.06% (251) | daunorubicin-DIM-transport integral membrane protein ABC |
| M. vanbaalenii PYR-1 | Mvan_3120 | - | 5e-46 | 36.65% (251) | multidrug ABC transporter inner membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1769|M.marinum_M ---MTSQEIAFAPAQSQHTD-------HSARLLIWQTLVQTQRILTRWSR
MUL_2012|M.ulcerans_Agy99 MIGMTSQEIAFAPAQSQHTD-------HSARLLIWQTLVQTQRILTRWSR
Mb2963|M.bovis_AF2122/97 MITTTSQEIELAPTRLPGSQ-------NAARLFVAQTLLQTNRLLTRWAR
Rv2938|M.tuberculosis_H37Rv MITTTSQEIELAPTRLPGSQ-------NAARLFVAQTLLQTNRLLTRWAR
MLBr_02350|M.leprae_Br4923 MITMISQTVGLVPASLQYPN-------NSVRALVSQTLLQTKRLLTRWAR
Mflv_3387|M.gilvum_PYR-GCK MTVESSP---PASYRVSGKHRRAHVWENSPRQLVPQVAVLTGRILRRWSR
Mvan_3120|M.vanbaalenii_PYR-1 MTLESPESLVSAPYRPGGRHRREKVWENSPKRLVPQVAVLTGRILRRWSR
MAV_3252|M.avium_104 ----------MMAHRLETQG-----------SLLTESWVQAGRLLLRWRR
MSMEG_6510|M.smegmatis_MC2_155 ----MSVELVRAPRGLRRVR-----------AVAMRMGAFALVELQKLRH
. . . : * : :
MMAR_1769|M.marinum_M DFVTLIEALVFPILFMLVLKIVLGNLIYAVTH-HDAMYSIVPLIALGAAI
MUL_2012|M.ulcerans_Agy99 DFVTLIEALVFPILFMLVLKIVLGNLIYAVTH-HDAMYSIVPLIALGAAI
Mb2963|M.bovis_AF2122/97 DYITVIGAIVLPILFMVVLNIVLGNLAYVVTH-DSGLYSIVPLIALGAAI
Rv2938|M.tuberculosis_H37Rv DYITVIGAIVLPILFMVVLNIVLGNLAYVVTH-DSGLYSIVPLIALGAAI
MLBr_02350|M.leprae_Br4923 DYVTIIGALVLPILFLVVLNIVLGNLAYVVTY-DSGLYSFVPLITLGAAI
Mflv_3387|M.gilvum_PYR-GCK DPATLVQSMVMPAVFLIALDIVLGDVIEAVTG-HSGLYGQVPLVALVGGM
Mvan_3120|M.vanbaalenii_PYR-1 DPATLVQSLVMPAVFLVALDIVLGDVIEQVTG-HSGLYGQVPLVALVGGM
MAV_3252|M.avium_104 DQAVLMGSLLLPVFLLFCYQIVLGEQVHRVTG-AQSVYGVVPMCAVISAL
MSMEG_6510|M.smegmatis_MC2_155 DRTELFTRMVQPALWLLIFGQTFSRLHVVDTGGVPYLAFLAPGIIAQSAL
* :. :: * . :. .:. * : .* ..:
MMAR_1769|M.marinum_M TGSAFVAIDLMRERTSGLLSRLWVLPVHRMSGLMARILADAVRILFTTLV
MUL_2012|M.ulcerans_Agy99 TGSAFVAIDLMRERTSGLLSRLWVLPVHRMSGLMARILADAVRILFTTLV
Mb2963|M.bovis_AF2122/97 TGSTFVAIDLMRERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLV
Rv2938|M.tuberculosis_H37Rv TGSTFVAIDLMRERSFGLLARLWVLPVHRASGLISRILANAIRTLVTTLV
MLBr_02350|M.leprae_Br4923 TGSTFVAIDLVRERSIGLLSRLWVLPIHRASGLLARILANTIRTFVTTLV
Mflv_3387|M.gilvum_PYR-GCK TGSIIGAVGIMRERDAGLLSRLWVVPVHRAAGLLARLAADFIRITAITLV
Mvan_3120|M.vanbaalenii_PYR-1 TGAIIGAVGIMREREAGLLSRFWVVPVHRAAGLLARLAADFVRIVVITLV
MAV_3252|M.avium_104 FGSLGNSVGITMDRQSRLLSRMWVLPIHRASAITGWVMAEVVRALIGTTL
MSMEG_6510|M.smegmatis_MC2_155 FISIFYGIQIIWDRDAGILAKLMVTPAPASALVAGKAFAAGVRSVVQVIG
: .: : :* :*::: * * : : . * :* .
MMAR_1769|M.marinum_M MLGVGILMGFEFRQGLIASLMWLCVPVTLGIAFAVMVTTVA-LYSSQAVI
MUL_2012|M.ulcerans_Agy99 MLGVGILMGFEFRQGLIASLMWLCVPVTLGIAFAVMVTTVA-LYSSQAVI
Mb2963|M.bovis_AF2122/97 MLGTGVVLGFRFRQGLIPSLMWISVPVILGIAIAAMVTTVA-LYTAQTVV
Rv2938|M.tuberculosis_H37Rv MLGTGVVLGFRFRQGLIPSLMWISVPVILGIAIAAMVTTVA-LYTAQTVV
MLBr_02350|M.leprae_Br4923 MLVTGVILGFRFRQGVIASLMWVSVPVIFGIAIAVMVTTVA-LYTEQTFV
Mflv_3387|M.gilvum_PYR-GCK VMSVGLVLGFRFEQGIPAAIAWVFMPALFGVTLSAAVLTLA-LLSSSTIA
Mvan_3120|M.vanbaalenii_PYR-1 VMVVGLALGFRFEQGILAAVVWVFMPALFGVALSAAVLTLA-LFSSSTIA
MAV_3252|M.avium_104 ITVIGLAMGLRFSQGWPAALLFLLVPSIVVTGFTALVMAMA-IRNNGRAA
MSMEG_6510|M.smegmatis_MC2_155 VVALAYLMGIALTLNPLRILAAMGVVVLGAAFFACLSMTLAGLVRKRDRL
: . :*: : . : : : :: ::* :
MMAR_1769|M.marinum_M VEGVELTQAIAIFFSTGLIPLDQYPHWIQPVVAHQPVSYAVSAMRGLSMG
MUL_2012|M.ulcerans_Agy99 VEGVELTQAIAIFFSTGLIPLDQYPHWIQPVVAHQPVSYAVSAMRGLSMG
Mb2963|M.bovis_AF2122/97 VEGVELVQAIAIFFSTGLVPLNSYPGWIQPFVAHQPVSYAIAAMRGFAMG
Rv2938|M.tuberculosis_H37Rv VEGVELVQAIAIFFSTGLVPLNSYPGWIQPFVAHQPVSYAIAAMRGFAMG
MLBr_02350|M.leprae_Br4923 VEAVELVQAIAVFLSTGLVPLNQYPGWIQPLVAHQPVSYAIAAMRGLSMG
Mflv_3387|M.gilvum_PYR-GCK PQATEILIAILMFFSIGFVPLDQYPEWLQPFVEHQPVSTTIEAMKGLSLE
Mvan_3120|M.vanbaalenii_PYR-1 PQATEIVIAILMFFSIGFVPLDQYPKWLQPFVEHQPVSTTIKAMKGLSLE
MAV_3252|M.avium_104 MTWLLGITFALVFVNPGATPIKLFPHWAQPLIRMQPVSPPIETMRALAHG
MSMEG_6510|M.smegmatis_MC2_155 MGIGQAITMPLFFASNALYPVDIMPTWLRWLSAVNPLSYEVNALRGLLIG
.* . . *:. * * : . :*:* : :::.:
MMAR_1769|M.marinum_M GPVLLPMIGVLLWTAGICAVCAVPLAVGWRRASTH--
MUL_2012|M.ulcerans_Agy99 GPVLLPMIGVLLWTAGICAVCAVPLAVGWRRASTH--
Mb2963|M.bovis_AF2122/97 GPVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH--
Rv2938|M.tuberculosis_H37Rv GPVLSPMIGMLVWTAGICVVCAVPLAIGYRRASTH--
MLBr_02350|M.leprae_Br4923 GPVLASMVAMLVWTAGICASCAVPLGVGYRRACTH--
Mflv_3387|M.gilvum_PYR-GCK GPIAQPVLFSVLWAAGIAAVCAVPLAIGYRRASKRG-
Mvan_3120|M.vanbaalenii_PYR-1 GPIAQPVLLSVLWAAGIAAVCAVPLAIGFRKASKRG-
MAV_3252|M.avium_104 GPIAWPLEITVAWAVVLVAVFIPVAVRGYRLAAEASG
MSMEG_6510|M.smegmatis_MC2_155 TPTNWVLDITVLVAAAVLGVVAASALLRRLVR-----
* : : :. :