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M. avium 104 MAV_3148 (ligD)

annotation: DNA polymerase LigD ligase subunit
coordinates: 3238982 - 3239980
length: 332

VTDFAALPDSVRAALRDEPVPQWCSPTLATLTEQRFSDPHWIFERKFDGMRCLAFRDGDRVRLLSRNRKP
LNGTYPELVEALAAQRETRFVLDGEVVAFEGRRTSFARLQGRLGITDPDVARASSVRIYYYVFDLLHLDG
KSTVAVPLIWRKRLLRKAIDFTDPLRYAPHRVGDGMAAYRAACGRGDEGVIAKRAESAYDGRRSENWLKF
KCVRDQEFVVGGYTSPKGKRLELGALLLGYYQGDQLRYAGKVGTGFDEATLHRLHQLLSGIACDTTPFTR
SLVPEAGAHWVRPELVVQIGFTEWTRDGKLRHPRYLGIRTDKDPTEVIRETR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3148ligD-100% (332)DNA polymerase LigD ligase subunit
M. avium 104MAV_1056-3e-4337.97% (295) ATP-dependent DNA ligase
M. avium 104MAV_0360ligC6e-2233.76% (237) ATP-dependent DNA ligase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0963-1e-4235.58% (312) ATP-dependent DNA ligase
M. gilvum PYR-GCKMflv_1828-2e-4135.53% (318) ATP-dependent DNA ligase
M. tuberculosis H37RvRv0938-1e-4235.58% (312) ATP-dependent DNA ligase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1033-9e-3935.74% (291) ATP-dependent DNA ligase
M. marinum MMMAR_4573-2e-4237.97% (295) ATP dependent DNA ligase
M. smegmatis MC2 155MSMEG_5570-7e-4436.08% (316) ATP-dependent DNA ligase
M. thermoresistible (build 8)TH_3391-2e-4138.56% (319) PUTATIVE ATP dependent DNA ligase
M. ulcerans Agy99MUL_4434-3e-4237.97% (295) ATP-dependent DNA ligase
M. vanbaalenii PYR-1Mvan_4915-1e-4436.81% (326) ATP-dependent DNA ligase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5570|M.smegmatis_MC2_155      -MERYER---------VRLTNPDKVLYPATG-----TTKAEVFDYYLSIA
TH_3391|M.thermoresistible__bu      -MERYER---------VKLTNPDKVLYPASG-----TTKAEVFEYYIEIA
Mflv_1828|M.gilvum_PYR-GCK          MVDRYDR---------VKLTNPDKVLYPASG-----TTKAQVFEYYVNVA
Mvan_4915|M.vanbaalenii_PYR-1       MVDRYER---------VKLTNPDKVLYPATGDRRRAVTKAEVFDYYVNVA
Mb0963|M.bovis_AF2122/97            MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYAGVA
Rv0938|M.tuberculosis_H37Rv         MGSASEQ--------RVTLTNADKVLYPATG-----TTKSDIFDYYAGVA
MMAR_4573|M.marinum_M               MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYTGIA
MUL_4434|M.ulcerans_Agy99           MGSAQAWPPGQANGPQVTLTNADKVLYPATG-----TTKSDVFGYYTGIA
MAB_1033|M.abscessus_ATCC_1997      ------------------------MLYPATDTSP-ATTKADVFGYYTAIA
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      QVMVPHIAGRPVTRKRWPNGVAEEAFFEKQLASSAPSWLERGSITHKSGT
TH_3391|M.thermoresistible__bu      DAMLPHIAGRPVTRKRWPNGVHEASFFEKQLASSAPDWLARGTITHKSRT
Mflv_1828|M.gilvum_PYR-GCK          EGMLPHIAGRAVTRKRWPNGVEESSFFEKQLASSAPDWLDRGTIAHKSGT
Mvan_4915|M.vanbaalenii_PYR-1       AAMLPHIAGRAVTRKRWPNGVTEESFFEKQLASSAPDWLGRGTIVHKSGT
Mb0963|M.bovis_AF2122/97            EVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHRSGT
Rv0938|M.tuberculosis_H37Rv         EVMLGHIAGRPATRKRWPNGVDQPAFFEKQLALSAPPWLSRATVAHRSGT
MMAR_4573|M.marinum_M               EVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHRSGT
MUL_4434|M.ulcerans_Agy99           EVMIPHIAGRPATRKRWPNGVDQASFFEKQLASSAPDWLPRASVVHRSGT
MAB_1033|M.abscessus_ATCC_1997      PFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHKSRY
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      TTYPIINTREGLAWVAQQASLEVHVPQWRFEDGDQ-----------GPAT
TH_3391|M.thermoresistible__bu      TTYPIIDTREGLAWIAQQAALEVHVPQWRFVAGGRSGR--DGKLTMGPAT
Mflv_1828|M.gilvum_PYR-GCK          TTYPVIDTVEGLAWIAQQAALEVHVPQWRFTRGGQSGAADGGDGKPGPAT
Mvan_4915|M.vanbaalenii_PYR-1       TTYPVIDTVEGLAWIAQQAALEVHVPQWRFV-----------DGSVGPAT
Mb0963|M.bovis_AF2122/97            TTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPGSGE-----LNPGPAT
Rv0938|M.tuberculosis_H37Rv         TTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEPGSGE-----LNPGPAT
MMAR_4573|M.marinum_M               TTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTSKGE---ILTPGPAT
MUL_4434|M.ulcerans_Agy99           TTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTSKGE---ILTPGPAT
MAB_1033|M.abscessus_ATCC_1997      VSYPLIDTSVALAWIAQQAALEVHVPQWRFAGE-----------NPGPAT
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      RIVFDLDPGEGVTMTQLCEIAHEVRALMTDLDLETYPLTSGSKGLHLYVP
TH_3391|M.thermoresistible__bu      RIVFDLDPGEGVTMRELCRVAHEVRDLITDIGLDTFPLTSGSKGLHLYVP
Mflv_1828|M.gilvum_PYR-GCK          RIVFDLDPGEGVTFRQLCEVAHEVRELITDIGLTTFPLTSGSKGLHLYVP
Mvan_4915|M.vanbaalenii_PYR-1       RIVFDLDPGEGVTFRQLCEVANEVRDLLADIGLRTFPLTSGSKGLHLYVP
Mb0963|M.bovis_AF2122/97            RLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHLYTP
Rv0938|M.tuberculosis_H37Rv         RLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHLYTP
MMAR_4573|M.marinum_M               RLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHLYTP
MUL_4434|M.ulcerans_Agy99           RLVFDLDPGEGVTMAQLAQVARAVRDLLADIGLSTLPLTSGSKGLHFYTP
MAB_1033|M.abscessus_ATCC_1997      RLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHLYVP
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      LAEPISSRGASVLARRVAQQLEQAMPKLVTATMTKSLRAGKVFLDWSQNN
TH_3391|M.thermoresistible__bu      LDEPISSQGASVLAKRVALQLEKAMPTLVTATMTKSVRTGKVFLDWSQNN
Mflv_1828|M.gilvum_PYR-GCK          LEDPISSRGASVLAKRVAQQLEQSMPKRVTATMTKSLRDGKVFLDWSQNN
Mvan_4915|M.vanbaalenii_PYR-1       LDEPISSRGASVLAKRVAQQLEQAMPMQVTATMTKSLRTGKVFVDWSQNN
Mb0963|M.bovis_AF2122/97            LDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWSQNS
Rv0938|M.tuberculosis_H37Rv         LDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWSQNS
MMAR_4573|M.marinum_M               LDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWSQNS
MUL_4434|M.ulcerans_Agy99           LDEPVSSKGATVLAKRVAQQLETVMPALVTATMTKSLRAGKVFLDWSQNS
MAB_1033|M.abscessus_ATCC_1997      LAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNS
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      AAKTTIAPYSLRGRDHPTVAAPRTWDEIADPELRHLRFDEVLDRLDEYGD
TH_3391|M.thermoresistible__bu      AAKTTIAPYSLRGREHPTVAAPRTWDEIDDPDLRHLTFTEVLDRVDRLGD
Mflv_1828|M.gilvum_PYR-GCK          GNKTTIAPYSLRGRERPTVAAPRTWDEIEDPDLRHLTFDEVLDRLERDGD
Mvan_4915|M.vanbaalenii_PYR-1       ANKTTIAPYSLRGREHPTVAAPRTWEEISDPDLRQLTFDEVLDRLDRDGD
Mb0963|M.bovis_AF2122/97            GSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARDGD
Rv0938|M.tuberculosis_H37Rv         GSKTTIAPYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARDGD
MMAR_4573|M.marinum_M               GSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTRDGD
MUL_4434|M.ulcerans_Agy99           GSKTTIAPYSLRGREQPTVAAPRSWEELDDPGLRQLTYDEVLARLTRDGD
MAB_1033|M.abscessus_ATCC_1997      GSKTTVAPYSLRGRAVPTVAAPRTWEELDDPGLRQLRYDEVLTRAQRDGD
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      LLAPLDADAPIADKLTTYRSMRDASKTPEPVPKEIPKTGNNDKFVIQEHH
TH_3391|M.thermoresistible__bu      LLAPMDADAPVADRLSSYRSMRDPARTPEPVPKTVAATGDDNRFVIQEHH
Mflv_1828|M.gilvum_PYR-GCK          LLADLDPPLPATDKLTRYRSMRDRTKTPEPVPAEPPETGANDKFVIQEHH
Mvan_4915|M.vanbaalenii_PYR-1       LLAGLDPPVPVPDRLTRYRSMRDTAKTPEPIPGDAPTTGNNDKFVIQEHH
Mb0963|M.bovis_AF2122/97            LLERLDADAPVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTFVIQEHH
Rv0938|M.tuberculosis_H37Rv         LLERLDADAPVADRLTRYRRMRDASKTPEPIPTAKPVTGDGNTFVIQEHH
MMAR_4573|M.marinum_M               LIAALDADLPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTFVIQEHH
MUL_4434|M.ulcerans_Agy99           LIAALDADLPGDDRLLKYRSMRNASKTPEPVPRARPVVGQGNTFVIQEHH
MAB_1033|M.abscessus_ATCC_1997      LLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSFVIQEHH
MAV_3148|M.avium_104                --------------------MTDFAALPDSVRAALR--------------
                                                        * : :  *:.:                   

MSMEG_5570|M.smegmatis_MC2_155      ARRLHYDLRLERDGVLVSFAVPKNLPETTAENRLAVHTEDHPIEYLAFHG
TH_3391|M.thermoresistible__bu      ARRLHYDLRLERDGVLVSWAIPKNLPDDPSVNHLAVHTEDHPLEYLTFHG
Mflv_1828|M.gilvum_PYR-GCK          ARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPMDYIDFAG
Mvan_4915|M.vanbaalenii_PYR-1       ARRLHYDFRLERDGVLVSWAVPKNLPDTPSVNHLAVHTEDHPMEYLTFAG
Mb0963|M.bovis_AF2122/97            ARRPHYDFRLERDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLEYATFEG
Rv0938|M.tuberculosis_H37Rv         ARRPHYDFRLECDGVLVSWAVPKNLPDNTSVNHLAIHTEDHPLEYATFEG
MMAR_4573|M.marinum_M               ARRLHYDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLEYATFEG
MUL_4434|M.ulcerans_Agy99           ARRLHDDFRLERDGVLVSWAVPKNLPETTSVNHLAVHTEDHPLEYATFEG
MAB_1033|M.abscessus_ATCC_1997      ATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYGSFEG
MAV_3148|M.avium_104                ------------DEPVPQWCSPT----------LATLTEQR---------
                                                *  : .:. *.          **  **::         

MSMEG_5570|M.smegmatis_MC2_155      SIPKGEYGAGDMVIWDSGSYETEKFRVP-EELDNPDDSHGEIIVTLHGEK
TH_3391|M.thermoresistible__bu      EIPEGEYGGGKMLIWDTGTYEAEKFN---DVGPDEDAEGGEVIITLHGEK
Mflv_1828|M.gilvum_PYR-GCK          EIPKGEYGGGEVHIWDTGTYETEKFR---DNPPDGPAKGGEVIVTLHGQK
Mvan_4915|M.vanbaalenii_PYR-1       EIPRGEYGGGEVYIWDTGTYETEKFR---DNPPDGPDRGGEVIVTLHGEK
Mb0963|M.bovis_AF2122/97            AIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIVNLHGGR
Rv0938|M.tuberculosis_H37Rv         AIPSGEYGAGKVIIWDSGTYDTEKFH----DDPHTG----EVIVNLHGGR
MMAR_4573|M.marinum_M               NIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGSEKGEVIVNLHGSR
MUL_4434|M.ulcerans_Agy99           NIPKGEYGAGKVIIWDSGTYDTEKFR----DDSRNGAEKGEVIVNLHGSR
MAB_1033|M.abscessus_ATCC_1997      TIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIVTLHGKR
MAV_3148|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      VDGRYALIQTKGKNWLAHRMKDQK---NARPEDFAPMLATEGSVAKYKAK
TH_3391|M.thermoresistible__bu      ISGRYALIQTDGKNWLAHKMKDQKPRTEIRPEDFTPMLATHGSVARLSAE
Mflv_1828|M.gilvum_PYR-GCK          IEGRYALIQTDGKNWLAHRMKDQQ---KPTAADLAPMLTTEGSVERLTRG
Mvan_4915|M.vanbaalenii_PYR-1       IDGRYALIQTDGKNWLAHRMKDQQ---RPTAADLAPMLTTHGSVQRLTKG
Mb0963|M.bovis_AF2122/97            ISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTVAGLKAS
Rv0938|M.tuberculosis_H37Rv         ISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTVAGLKAS
MMAR_4573|M.marinum_M               ISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSVAGLESG
MUL_4434|M.ulcerans_Agy99           ISGRYALIQTNGDQWLAHRMK---DQTAFDFDTLAPMLTSHGSVAGLESG
MAB_1033|M.abscessus_ATCC_1997      ITGRYALIRTNGKQWLVHRMKDQRPAGSMPVG-LAPMLPTTGSVAGLTAE
MAV_3148|M.avium_104                ----------------------------------------------FSDP
                                                                                      

MSMEG_5570|M.smegmatis_MC2_155      QWAFEGKWDGYRVIIDADHGQLQIRSRTGREVTGEYPQFKALAADLAEHH
TH_3391|M.thermoresistible__bu      THAFEGKWDGYRLLVHIDHGKLCLRSRSGRDVTKEFPTLQAMAADLADHQ
Mflv_1828|M.gilvum_PYR-GCK          QWAFEGKWDGYRLLVDADHGKLTLRSRRGRDVTAEYPQLKALAADLADHH
Mvan_4915|M.vanbaalenii_PYR-1       QWAFEGKWDGYRLLVEADHGRLALRSRNGRDVTAEYPQLQALAADLADHH
Mb0963|M.bovis_AF2122/97            QWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAEDLADHH
Rv0938|M.tuberculosis_H37Rv         QWAFEGKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAEDLADHH
MMAR_4573|M.marinum_M               QWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTAEYPQLRSLAADLADHH
MUL_4434|M.ulcerans_Agy99           QWAFEGKWDGYRLLVEADHGALRLRSRSGRDVTTEYPQLRSLAADLADHH
MAB_1033|M.abscessus_ATCC_1997      EWAFEGKWDGYRLILECDRGQLRALARSGRDVTAEFPALQRLAHELSDHR
MAV_3148|M.avium_104                HWIFERKFDGMRCLAFRDGDRVRLLSRNRKPLNGTYPELVEALAAQRETR
                                       ** *:** * :   * . :   :*  : :.  :* :        : :

MSMEG_5570|M.smegmatis_MC2_155      VVLDGEAVALDESGVPSFGQMQ----------NRARSTRVEFWAFDILWL
TH_3391|M.thermoresistible__bu      VVLDGEVVALDGSGVPSFGEMQ----------NRARATHIEFWAFDILWL
Mflv_1828|M.gilvum_PYR-GCK          VILDGEAVALDEDGVPSFGEMQ----------NRARSTRVEFWAFDILFL
Mvan_4915|M.vanbaalenii_PYR-1       VILDGEAVALDESGVPSFREMQ----------NRARSTRVEFWAFDILFL
Mb0963|M.bovis_AF2122/97            VVLDGEAVVLDSSGVPSFSQMQ----------NRGRDTRVEFWAFDLLYL
Rv0938|M.tuberculosis_H37Rv         VVLDGEAVVLDSSGVPSFSQMQ----------NRGRDTRVEFWAFDLLYL
MMAR_4573|M.marinum_M               VVLDGELVALDSSGVPSFNEMQ----------NRVRATRIEFWAFDLLFL
MUL_4434|M.ulcerans_Agy99           VVLDGELVALDSSGVPSFNEMQ----------NRVRATRIEFWAFDLLFL
MAB_1033|M.abscessus_ATCC_1997      VVLDGEVVVPDRKGLPSFALLQ----------NRTPGADIRFWAFDLLYL
MAV_3148|M.avium_104                FVLDGEVVAFEGR-RTSFARLQGRLGITDPDVARASSVRIYYYVFDLLHL
                                    .:**** *. :    .**  :*           *   . : ::.**:* *

MSMEG_5570|M.smegmatis_MC2_155      DGRSLLRAKYSDRRKILEALADG-GGLIVPDQLPGD-GPEAMEHVRKKRF
TH_3391|M.thermoresistible__bu      DGRSLLRAKHSDRRRVLLALAEK-DGLIVPDLLPGDTGAEALEYARERGF
Mflv_1828|M.gilvum_PYR-GCK          DGRLLTKATYTDRRKLLEALAEG-GGLIVPPALEGD-GPEALEYARSQRW
Mvan_4915|M.vanbaalenii_PYR-1       DGRSLLRAKYTDRRRVLEALADG-GGLIVPPLIGADTGAEALETARKRGW
Mb0963|M.bovis_AF2122/97            DGRALLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGW
Rv0938|M.tuberculosis_H37Rv         DGRALLGTRYQDRRKLLETLANA-TSLTVPELLPGD-GAQAFACSRKHGW
MMAR_4573|M.marinum_M               DGRSLLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGW
MUL_4434|M.ulcerans_Agy99           DGRSLLRARYRDRRKLLETLGSA-GNLIVPELLPGD-GAEALAYSHKRGW
MAB_1033|M.abscessus_ATCC_1997      DGKSLLRTKYRDRRRLLEVLVTGTESMTVPQQLSGD-GAAALAYSQDQGW
MAV_3148|M.avium_104                DGKSTVAVPLIWRKRLLRKAIDFTDPLRYAPHRVGD-GMAAYRAACGRGD
                                    **:    .    *:::*         :  .    .* *  *      :  

MSMEG_5570|M.smegmatis_MC2_155      EGVVAKKWDSTYQPGRRSSSWIKDKIWNTQEVVIGGWRQGEGGRSSGIGA
TH_3391|M.thermoresistible__bu      EGVVAKRHDSIYQPGRRSKAWIKDKIWNMQEVVIGGWRKGEGGRSSGIGA
Mflv_1828|M.gilvum_PYR-GCK          EGVIAKKRDSTYQPGRRSSAWIKDKIWNTQEVVIGGWRQGEGGRTSGIGA
Mvan_4915|M.vanbaalenii_PYR-1       EGVVAKKRDSTYQPGRRSSSWIKDKLWNTQEVVIGGWRQGEGGRTSGIGA
Mb0963|M.bovis_AF2122/97            EGVIAKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGS
Rv0938|M.tuberculosis_H37Rv         EGVIAKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGRSSGVGS
MMAR_4573|M.marinum_M               EGVIAKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGS
MUL_4434|M.ulcerans_Agy99           EGVIAKRRDSGYQPGRRSSAWIKDKHWNTQEVVIGGWRVGEGGRSSGIGS
MAB_1033|M.abscessus_ATCC_1997      EGVVAKRLDSTYVPG-RTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGS
MAV_3148|M.avium_104                EGVIAKRAES-AYDGRRSENWLKFKCVRDQEFVVGGYTSPKGKR-LELGA
                                    ***:**: :*    * *   *:* *    **.*:**:   :* *   :*:

MSMEG_5570|M.smegmatis_MC2_155      LVLGIPGP---EGLQFVGRVGTGFTEKELSKLKDMLKPLHTDESPFNAPL
TH_3391|M.thermoresistible__bu      LVLGIPTE---GGLQFVGRVGTGFTDKQLAELKQLLAPLETDESPFVDPL
Mflv_1828|M.gilvum_PYR-GCK          LVLGVPDD---DGLHFVGRVGTGFTDKQLASLKKTLEPLRTDESPFAAEL
Mvan_4915|M.vanbaalenii_PYR-1       LMLGIPAGGVAGGLQFVGRVGTGFTEKELASLKETLAPLHTDESPFATEL
Mb0963|M.bovis_AF2122/97            LLMGIPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPL
Rv0938|M.tuberculosis_H37Rv         LLMGIPGP---GGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPL
MMAR_4573|M.marinum_M               LLMGIPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAAL
MUL_4434|M.ulcerans_Agy99           LLMGIPGP---SGLHFAGRVGTGFTERDLANLKKTLAPLHTDESPFDAAL
MAB_1033|M.abscessus_ATCC_1997      LLMGIPVE---GGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPL
MAV_3148|M.avium_104                LLLGYYQG---DQLRYAGKVGTGFDEATLHRLHQLLSGIACDTTPFTRSL
                                    *::*         *::.*:****: :  *  *:. *  :    :**   *

MSMEG_5570|M.smegmatis_MC2_155      PKVDARGVTFVRPELVGEVRYSERTSDGRLRQPSWRGLRPDKTPDEVVWE
TH_3391|M.thermoresistible__bu      PRPDAKGVTYVRPELVGEVRYSERTADNRLRQPSWRGLRPDKSPDEVRWE
Mflv_1828|M.gilvum_PYR-GCK          PKQDAKGVTFVRPELVGEVRYSERTSDGRLRQASWRGLRDDKVPEDVRWE
Mvan_4915|M.vanbaalenii_PYR-1       PKQDAKGVTFVRPELVGEVRYSERTSDNRLRQPSWRGLRTDKTPDEVVWE
Mb0963|M.bovis_AF2122/97            PARDAKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE
Rv0938|M.tuberculosis_H37Rv         PARDAKGITYVKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE
MMAR_4573|M.marinum_M               PAREAKGVTFVAPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE
MUL_4434|M.ulcerans_Agy99           PAREAKGVTFVVPTLVGEVRYSEWTPDDRLRQSSWRGLRPDKNPSEVVRE
MAB_1033|M.abscessus_ATCC_1997      STVEAKDVQFVEPVLVAEVRYGDRTPGGILKHSSWRGLRTDKSVRDVELD
MAV_3148|M.avium_104                VP--EAGAHWVRPELVVQIGFTEWTRDGKLRHPRYLGIRTDKDPTEVIRE
                                          .  :* * ** :: : : *  . *::. : *:* **   :*  :

MSMEG_5570|M.smegmatis_MC2_155      --
TH_3391|M.thermoresistible__bu      --
Mflv_1828|M.gilvum_PYR-GCK          G-
Mvan_4915|M.vanbaalenii_PYR-1       --
Mb0963|M.bovis_AF2122/97            --
Rv0938|M.tuberculosis_H37Rv         --
MMAR_4573|M.marinum_M               --
MUL_4434|M.ulcerans_Agy99           --
MAB_1033|M.abscessus_ATCC_1997      LG
MAV_3148|M.avium_104                TR