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DFELDAGQRAWLAEIREFLRDNVTEELRAELAQHDLEFPDGEVARFRRKIGAKGWFGLNWPREYGGLGLG AVHLHLLMSEFEYWGVPGPDLTVTSVAPMIMRHGTERNKTEWLPLIAKGEMICAVGYSEPDAGTDLANLR TSAVRDGEEWVINGTKIWNSGAQRATHEWLCVRTDPTGTRHRGISVVIVPIDSPGIDIRPLYAWSGYRTN EVHFHDVRVPVTNLIGEVNHGWTYITGALDLERGALTNAGDLRRAVEELHELARRPRRDRTVPADDPWLR RRLAQAEADVAVATLMGYEAASILDSGVIPTVEVSVEKIFTSELRQRIADLALDLLGVDGLLAHRSENAP LAGKFERLYRAAPLMRFGGGTNEVLRDIIAQRGHAMPSYGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3008 | - | - | 100% (392) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1338 | - | 7e-73 | 39.95% (388) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_0652 | - | 2e-72 | 39.89% (376) | putative acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3534 | fadE26 | 1e-72 | 40.05% (387) | acyl-CoA dehydrogenase FADE26 |
| M. gilvum PYR-GCK | Mflv_1551 | - | 4e-69 | 39.01% (382) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3504 | fadE26 | 1e-72 | 40.05% (387) | acyl-CoA dehydrogenase FADE26 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-23 | 25.86% (379) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4158 | - | 7e-73 | 39.05% (379) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_4992 | fadE26 | 7e-73 | 40.26% (380) | acyl-CoA dehydrogenase FadE26 |
| M. smegmatis MC2 155 | MSMEG_5906 | - | 7e-70 | 39.01% (382) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4647 | - | 1e-82 | 42.53% (388) | PUTATIVE putative acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_4067 | fadE26 | 2e-71 | 39.74% (380) | acyl-CoA dehydrogenase FadE26 |
| M. vanbaalenii PYR-1 | Mvan_5206 | - | 4e-70 | 39.27% (382) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3534|M.bovis_AF2122/97 -MRISYTPQQEELRR-ELRSYFATLMTPERREALSSVQGEYGV-GNVYRE
Rv3504|M.tuberculosis_H37Rv -MRISYTPQQEELRR-ELRSYFATLMTPERREALSSVQGEYGV-GNVYRE
MMAR_4992|M.marinum_M -MRISYTPEQEELRR-ELRSYFTTLMTPERREALSSVQGEYGT-GNVYRE
MUL_4067|M.ulcerans_Agy99 -MRISYTPEQEELRR-ELRSYFTTLMTPERREALSSVQGEYGT-GNVYRE
MAB_4158|M.abscessus_ATCC_1997 -MHIAYTPEQEELRR-ELRAYFDKLLTPERREALASNQGEYGS-GNVYRE
Mflv_1551|M.gilvum_PYR-GCK -MRIGYTPEQEELRR-ELRSYFTKLMTPERAEALAASDGEMGR-GNVYRE
Mvan_5206|M.vanbaalenii_PYR-1 -MRIGYTPEQEELRR-ELRAYFTKLMTPERAEALAASDGEMGR-GNVYRE
MSMEG_5906|M.smegmatis_MC2_155 -MRIGYTPEQEELRR-ELRAYFSKLMTPERVEALSSSEGEMGR-GNVYRE
TH_4647|M.thermoresistible__bu -MDFDYTPEQEALRR-DFRRRLEAVMTPERRAAIA---GQLEG-GPAVAE
MAV_3008|M.avium_104 -MDFELDAGQRAWLA-EIREFLRDNVTEELRAELAQHDLEFPD-GEVAR-
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
: . : : : : :: : .
Mb3534|M.bovis_AF2122/97 TIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFL-TIN
Rv3504|M.tuberculosis_H37Rv TIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFL-TIN
MMAR_4992|M.marinum_M TVAQMGKDGWLTLNWPKEYGGQDRSPMDSLIFTDEAAIAGAPVPFL-TIN
MUL_4067|M.ulcerans_Agy99 TVAQMGKNGWLTLNWPKEYGGQDRSPMDSLIFTDEAAIAGAPVPFL-TIN
MAB_4158|M.abscessus_ATCC_1997 TVEQMGADGWLALGWPKEFGGQDRSVMDQLIFTDEAAIAGAPVPFL-TIN
Mflv_1551|M.gilvum_PYR-GCK TVAQMGKDGWLTLSWPEEFGGQARPPMDGLIFNDEAAIANVPVPFL-TIN
Mvan_5206|M.vanbaalenii_PYR-1 TVAQMGKDGWLTLSWPKEFGGQARPPMDGLIFNDEAAIANVPVPFL-TIN
MSMEG_5906|M.smegmatis_MC2_155 TVAQMGKDGWLTLSWPKEFGGQARPPMDGLIFTDEAAIAGAPVPFL-TIN
TH_4647|M.thermoresistible__bu CRRALGEAGLLGVSWPVEYGGGGLSALEQYIFAEEARRVNAPLPMI-TLN
MAV_3008|M.avium_104 FRRKIGAKGWFGLNWPREYGGLGLGAVHLHLLMSEFEYWGVPGPDL-TVT
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
:. * : * *:** : :. .* ... . : ::.
Mb3534|M.bovis_AF2122/97 SVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTA
Rv3504|M.tuberculosis_H37Rv SVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTA
MMAR_4992|M.marinum_M SVAPT-IMAFGTDEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLANLRTTA
MUL_4067|M.ulcerans_Agy99 SVAPT-IMAFGTDEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLANLRTTA
MAB_4158|M.abscessus_ATCC_1997 SVAPT-IMHFGTDEQKKFFLPKIAAGKLHFSIGYSEPGAGTDLASLRTSA
Mflv_1551|M.gilvum_PYR-GCK SVAPT-IMHFGTEEQKKFFLPRIAKGDLHFSIGYSEPGAGTDLASLRTTA
Mvan_5206|M.vanbaalenii_PYR-1 SVAPT-IMAFGTEEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLAALRTTA
MSMEG_5906|M.smegmatis_MC2_155 SVAPT-IMAFGTEEQKKFFLPKIASGELHFSIGYSEPGAGTDLASLRTTA
TH_4647|M.thermoresistible__bu TVGPT-LMQFGTEEQKQKFLPAILRGTVDFAIGYSEPGAGSDLASLRTTA
MAV_3008|M.avium_104 SVAPM-IMRHGTERNKTEWLPLIAKGEMICAVGYSEPDAGTDLANLRTSA
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
.:.. :: *::. * ** : : . ** **:* * :** *
Mb3534|M.bovis_AF2122/97 VRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVP
Rv3504|M.tuberculosis_H37Rv VRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVP
MMAR_4992|M.marinum_M VRDGDDYVINGQKMWTSLIAYADWVWLAVRTNPE---AKKHRGISMLVVP
MUL_4067|M.ulcerans_Agy99 VRDGDDYLINGQKMWTSLIAYADWVCLAVRTNPE---AKKHRGISMLVVP
MAB_4158|M.abscessus_ATCC_1997 VRDGDDYIVNGQKMWTSLIEYADYIWLAVRTNTE---VKKHRGISMLIVP
Mflv_1551|M.gilvum_PYR-GCK VHDGDDYVINGQKMWTSLIAYADYVWLAVRTNTE---AKKHRGISMLIVP
Mvan_5206|M.vanbaalenii_PYR-1 VRDGDDYVINGQKMWTSLIAYADYVWLAVRTNPE---AKKHRGISMLIVP
MSMEG_5906|M.smegmatis_MC2_155 VRDGDDYVINGQKMWTSLIAYADYVWLAVRTNPE---AKKHRGISMLIVP
TH_4647|M.thermoresistible__bu VRDGDEWVIDGSKMFTSGAEYADYIWLAARTDPE---ARKHKGITLFIVP
MAV_3008|M.avium_104 VRDGEEWVINGTKIWNSGAQRATHEWLCVRTDPT---GTRHRGISVVIVP
MLBr_00737|M.leprae_Br4923 KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD----KGANGISAFIVH
**::::::* * : : : : . *:. .**: .:*
Mb3534|M.bovis_AF2122/97 TTAEGFSWTPVHT---MAGPDTSATYYSDVRVPVANRVGEENAGWKLVTN
Rv3504|M.tuberculosis_H37Rv TTAEGFSWTPVHT---MAGPDTSATYYSDVRVPVANRVGEENAGWKLVTN
MMAR_4992|M.marinum_M TTAEGFSWTPVHT---MAGPDTSATYYTDVRVPVTNLIGEENAGWKLVTN
MUL_4067|M.ulcerans_Agy99 TTAEGFSWTPVHT---MAGPDTSATYYTDVRVPVTNLIGEENAGWKLVTN
MAB_4158|M.abscessus_ATCC_1997 TTAEGFSYTKVHT---MAGPGTSATYYQDVRVPVTSRVGEENAGWKLVTN
Mflv_1551|M.gilvum_PYR-GCK TTAEGFSWTPVHT---VSGVDTSATYYQDVRVPKSALVGEENGGWKLVTN
Mvan_5206|M.vanbaalenii_PYR-1 TTAEGFSWTPVHT---MSGVDTSATYYQDVRVPVSSLVGEENAGWKLVTN
MSMEG_5906|M.smegmatis_MC2_155 TTAEGFSWTPVHT---MSGVDTSATYYQDVRVPVTNLVGEENQGWKLVTN
TH_4647|M.thermoresistible__bu TDSPGFSWKPLHT---MPGVSTYYTFYDDVRVPDDNIVGNLNEGWKLVTN
MAV_3008|M.avium_104 IDSPGIDIRPLYA---WSGYRTNEVHFHDVRVPVTNLIGEVNHGWTYITG
MLBr_00737|M.leprae_Br4923 KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
*:. * * .: . *:* :*: . *:.
Mb3534|M.bovis_AF2122/97 QLNHERVALVSPAP-IFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLAR
Rv3504|M.tuberculosis_H37Rv QLNHERVALVSPAP-IFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLAR
MMAR_4992|M.marinum_M QLNHERVALVSSAP-ISMALREVREWAQNTKDAGGARLIDSEWVQLNLAR
MUL_4067|M.ulcerans_Agy99 QLNHERVALVSSAP-ISMALREVREWAQNTKDAGGARLIDSEWVQLNLAR
MAB_4158|M.abscessus_ATCC_1997 QLNHERVALVSSAP-IITALREVREWAQNTKGPGG-RIIDAEWVQLNLAR
Mflv_1551|M.gilvum_PYR-GCK QLNHERVALVSAQP-IFVALNGVREWAQNTKDVHGNRVIDSEWVQLNLAR
Mvan_5206|M.vanbaalenii_PYR-1 QLNHERVALVSAQP-IFVALNGVREWAQNTKDVHGKRLIDSEWVQLNLAR
MSMEG_5906|M.smegmatis_MC2_155 QLNHERVALVSAQP-IYVALNGVREWAQNTKDVHGKRLIDSEWVQLNLAR
TH_4647|M.thermoresistible__bu QLNLERAALGNLGA-LEPLFEKTLQWARTTP-ADGGHIIDIPWVQQVLAR
MAV_3008|M.avium_104 ALDLERGALTNAGD-LRRAVEELHELARRPR-RDRTVPADDPWLRRRLAQ
MLBr_00737|M.leprae_Br4923 TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
*: * :: : :: **
Mb3534|M.bovis_AF2122/97 VHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLL
Rv3504|M.tuberculosis_H37Rv VHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLL
MMAR_4992|M.marinum_M VHAKVEVLKLINWELASN-----DAAPSPADASAAKVFGTELATEAYRLL
MUL_4067|M.ulcerans_Agy99 VHAKVEVLKLINWELASN-----DAAPSPADASAAKVFGTELATEAYRLL
MAB_4158|M.abscessus_ATCC_1997 VHAKAEYLKLINWELAST----TDAAPSPADASATKVFGTELATEAYRLL
Mflv_1551|M.gilvum_PYR-GCK VHAKAEVLKLINWELASS----TDTAPSPADASAAKVFGTELATEAYRLL
Mvan_5206|M.vanbaalenii_PYR-1 VHAKAEVLKLINWELASA----TDAAPSPADASAAKVYGTELATEAYRLL
MSMEG_5906|M.smegmatis_MC2_155 VHAKAEVLKLINWELAS-----TEAAPSPADASAAKVYGTELATEAYRLL
TH_4647|M.thermoresistible__bu VEAQVSAYRLMNLRVNAS---MSSGGLGMAEASAAKVFGTELTQRVAREL
MAV_3008|M.avium_104 AEADVAVATLMGYEAASIL---DSGVIPTVEVSVEKIFTSELRQRIADLA
MLBr_00737|M.leprae_Br4923 MAMKVEAARLIVYAAAARAE--RGEPDLGFISAASKCFASDIAMEVTTDA
.. *: : :. * : ::: .
Mb3534|M.bovis_AF2122/97 MEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMV
Rv3504|M.tuberculosis_H37Rv MEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMV
MMAR_4992|M.marinum_M MEVLGTAATLRQDSPGALLHGRVERMHRACLILTFGGGTNEVQRDIIGMV
MUL_4067|M.ulcerans_Agy99 MEVLGTAATLRQDSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMV
MAB_4158|M.abscessus_ATCC_1997 MEVLGTAATLRQDSPGAQLRGRVERMHRACLILTFGGGTNEVQRDIIAMT
Mflv_1551|M.gilvum_PYR-GCK MEVLGTAATLRTNSPGAVLRGRIERMHRSCLILTFGGGTNEIQRDIIGMV
Mvan_5206|M.vanbaalenii_PYR-1 MEVLGTAATLRTNSPGALLRGRIERMHRSCLILTFGGGTNEIQRDIIGMV
MSMEG_5906|M.smegmatis_MC2_155 MEVLGTSATLRGDTRGALLRGRVERFHRSALILTFGGGTNEIQRDIIGMV
TH_4647|M.thermoresistible__bu LEVLGADGTRKG--ADAPLRGELEHAYRLAVINTFGGGANELQRDIIAMA
MAV_3008|M.avium_104 LDLLGVDGLLAHRSENAPLAGKFERLYRAAPLMRFGGGTNEVLRDIIAQR
MLBr_00737|M.leprae_Br4923 VQLFGGAG--------YTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRA
::::* . .*: * . : : *:*:: * ::.
Mb3534|M.bovis_AF2122/97 ALGLPRANR-------
Rv3504|M.tuberculosis_H37Rv ALGLPRANR-------
MMAR_4992|M.marinum_M ALGLPRANR-------
MUL_4067|M.ulcerans_Agy99 ALGLPRANR-------
MAB_4158|M.abscessus_ATCC_1997 ALGQPAASR-------
Mflv_1551|M.gilvum_PYR-GCK ALGLPRVNR-------
Mvan_5206|M.vanbaalenii_PYR-1 ALGLPRVNR-------
MSMEG_5906|M.smegmatis_MC2_155 ALGLPRVNR-------
TH_4647|M.thermoresistible__bu GLGMPRAPRDLRATAS
MAV_3008|M.avium_104 GHAMPSYGR-------
MLBr_00737|M.leprae_Br4923 LLR-------------