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M. thermoresistible (build 8) TH_4647 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 1186016 - 1187203
length: 396

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4647--100% (396)putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_3993-e-10852.26% (398) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_4261-2e-8946.19% (394) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3534fadE261e-10751.25% (400) acyl-CoA dehydrogenase FADE26
M. gilvum PYR-GCKMflv_1551-1e-10450.76% (394) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3504fadE261e-10751.25% (400) acyl-CoA dehydrogenase FADE26
M. leprae Br4923MLBr_00737fadE251e-3129.38% (388) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_4158-1e-10550.64% (393) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_4992fadE261e-10650.63% (395) acyl-CoA dehydrogenase FadE26
M. avium 104MAV_1338-1e-17474.49% (392) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5906-1e-10651.27% (394) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4067fadE261e-10550.38% (395) acyl-CoA dehydrogenase FadE26
M. vanbaalenii PYR-1Mvan_5206-1e-10551.02% (394) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_4647|M.thermoresistible__bu      ---MDFDYTPEQEALRRDFRRRLEAVMTPERRAAIA---GQLEGGPAVAE
MAV_1338|M.avium_104                ---MDLEYTPEQQQLRAEIRATLQTVMTPERVAAVS---EQMDGGPAVRE
Mb3534|M.bovis_AF2122/97            ---MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRE
Rv3504|M.tuberculosis_H37Rv         ---MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRE
MMAR_4992|M.marinum_M               ---MRISYTPEQEELRRELRSYFTTLMTPERREALSSVQGEYGTGNVYRE
MUL_4067|M.ulcerans_Agy99           ---MRISYTPEQEELRRELRSYFTTLMTPERREALSSVQGEYGTGNVYRE
MAB_4158|M.abscessus_ATCC_1997      ---MHIAYTPEQEELRRELRAYFDKLLTPERREALASNQGEYGSGNVYRE
Mflv_1551|M.gilvum_PYR-GCK          ---MRIGYTPEQEELRRELRSYFTKLMTPERAEALAASDGEMGRGNVYRE
Mvan_5206|M.vanbaalenii_PYR-1       ---MRIGYTPEQEELRRELRAYFTKLMTPERAEALAASDGEMGRGNVYRE
MSMEG_5906|M.smegmatis_MC2_155      ---MRIGYTPEQEELRRELRAYFSKLMTPERVEALSSSEGEMGRGNVYRE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                              :   *  : .     : :  .    .        .    *

TH_4647|M.thermoresistible__bu      CRRALGEAGLLGVSWPVEYGGGGLSALEQYIFAEEARRVNAPLPMI-TLN
MAV_1338|M.avium_104                CVRALAAANLLGVGWPKEYGGRGFSAIEQFIFAEEARRVSAPIPLV-TLN
Mb3534|M.bovis_AF2122/97            TIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFL-TIN
Rv3504|M.tuberculosis_H37Rv         TIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPFL-TIN
MMAR_4992|M.marinum_M               TVAQMGKDGWLTLNWPKEYGGQDRSPMDSLIFTDEAAIAGAPVPFL-TIN
MUL_4067|M.ulcerans_Agy99           TVAQMGKNGWLTLNWPKEYGGQDRSPMDSLIFTDEAAIAGAPVPFL-TIN
MAB_4158|M.abscessus_ATCC_1997      TVEQMGADGWLALGWPKEFGGQDRSVMDQLIFTDEAAIAGAPVPFL-TIN
Mflv_1551|M.gilvum_PYR-GCK          TVAQMGKDGWLTLSWPEEFGGQARPPMDGLIFNDEAAIANVPVPFL-TIN
Mvan_5206|M.vanbaalenii_PYR-1       TVAQMGKDGWLTLSWPKEFGGQARPPMDGLIFNDEAAIANVPVPFL-TIN
MSMEG_5906|M.smegmatis_MC2_155      TVAQMGKDGWLTLSWPKEFGGQARPPMDGLIFTDEAAIAGAPVPFL-TIN
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                        :   .   :  * *:**     :   *. :*.  .... .:: ::*

TH_4647|M.thermoresistible__bu      TVGPT-LMQFGTEEQKQKFLPAILRGTVDFAIGYSEPGAGSDLASLRTTA
MAV_1338|M.avium_104                TVGPT-LMHYGTDEQKRRFLPAILDGTVEFAIGYSEPGAGSDLASVHTTA
Mb3534|M.bovis_AF2122/97            SVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTA
Rv3504|M.tuberculosis_H37Rv         SVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDLANLRTTA
MMAR_4992|M.marinum_M               SVAPT-IMAFGTDEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLANLRTTA
MUL_4067|M.ulcerans_Agy99           SVAPT-IMAFGTDEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLANLRTTA
MAB_4158|M.abscessus_ATCC_1997      SVAPT-IMHFGTDEQKKFFLPKIAAGKLHFSIGYSEPGAGTDLASLRTSA
Mflv_1551|M.gilvum_PYR-GCK          SVAPT-IMHFGTEEQKKFFLPRIAKGDLHFSIGYSEPGAGTDLASLRTTA
Mvan_5206|M.vanbaalenii_PYR-1       SVAPT-IMAFGTEEQKKFFLPKIAAGDLHFSIGYSEPGAGTDLAALRTTA
MSMEG_5906|M.smegmatis_MC2_155      SVAPT-IMAFGTEEQKKFFLPKIASGELHFSIGYSEPGAGTDLASLRTTA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                    .:..  ::  *::* *: .** :       : . **  **:* * ::* *

TH_4647|M.thermoresistible__bu      VRDGDEWVIDGSKMFTSGAEYADYIWLAARTDPE---ARKHKGITLFIVP
MAV_1338|M.avium_104                VRVGDEYVINGQKMFTSGAAYADYIWLAVRTDPD---AKKHKGISILIVP
Mb3534|M.bovis_AF2122/97            VRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVP
Rv3504|M.tuberculosis_H37Rv         VRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRGISVLIVP
MMAR_4992|M.marinum_M               VRDGDDYVINGQKMWTSLIAYADWVWLAVRTNPE---AKKHRGISMLVVP
MUL_4067|M.ulcerans_Agy99           VRDGDDYLINGQKMWTSLIAYADWVCLAVRTNPE---AKKHRGISMLVVP
MAB_4158|M.abscessus_ATCC_1997      VRDGDDYIVNGQKMWTSLIEYADYIWLAVRTNTE---VKKHRGISMLIVP
Mflv_1551|M.gilvum_PYR-GCK          VHDGDDYVINGQKMWTSLIAYADYVWLAVRTNTE---AKKHRGISMLIVP
Mvan_5206|M.vanbaalenii_PYR-1       VRDGDDYVINGQKMWTSLIAYADYVWLAVRTNPE---AKKHRGISMLIVP
MSMEG_5906|M.smegmatis_MC2_155      VRDGDDYVINGQKMWTSLIAYADYVWLAVRTNPE---AKKHRGISMLIVP
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD----KGANGISAFIVH
                                       **:::::* * : :    : :  : . *:.:    :  .**: ::* 

TH_4647|M.thermoresistible__bu      TDSPGFSWKPLHT---MPGVSTYYTFYDDVRVPDDNIVGNLNEGWKLVTN
MAV_1338|M.avium_104                TSSPGFSWQPLHT---MPGISTFYTFYDDVRVPVSALVGAENQGWQLITT
Mb3534|M.bovis_AF2122/97            TTAEGFSWTPVHT---MAGPDTSATYYSDVRVPVANRVGEENAGWKLVTN
Rv3504|M.tuberculosis_H37Rv         TTAEGFSWTPVHT---MAGPDTSATYYSDVRVPVANRVGEENAGWKLVTN
MMAR_4992|M.marinum_M               TTAEGFSWTPVHT---MAGPDTSATYYTDVRVPVTNLIGEENAGWKLVTN
MUL_4067|M.ulcerans_Agy99           TTAEGFSWTPVHT---MAGPDTSATYYTDVRVPVTNLIGEENAGWKLVTN
MAB_4158|M.abscessus_ATCC_1997      TTAEGFSYTKVHT---MAGPGTSATYYQDVRVPVTSRVGEENAGWKLVTN
Mflv_1551|M.gilvum_PYR-GCK          TTAEGFSWTPVHT---VSGVDTSATYYQDVRVPKSALVGEENGGWKLVTN
Mvan_5206|M.vanbaalenii_PYR-1       TTAEGFSWTPVHT---MSGVDTSATYYQDVRVPVSSLVGEENAGWKLVTN
MSMEG_5906|M.smegmatis_MC2_155      TTAEGFSWTPVHT---MSGVDTSATYYQDVRVPVTNLVGEENQGWKLVTN
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALA
                                    .   ***    ..   : *  *   :: . *:*    :*  . *::    

TH_4647|M.thermoresistible__bu      QLNLERAALGNLGA-LEPLFEKTLQWARTT-PADGGHIIDIPWVQQVLAR
MAV_1338|M.avium_104                QLNFERAALGNLGA-LEPLFDKTLDWALST-ELDGGRVIDQPWVRSALAR
Mb3534|M.bovis_AF2122/97            QLNHERVALVSPAP-IFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLAR
Rv3504|M.tuberculosis_H37Rv         QLNHERVALVSPAP-IFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLAR
MMAR_4992|M.marinum_M               QLNHERVALVSSAP-ISMALREVREWAQNTKDAGGARLIDSEWVQLNLAR
MUL_4067|M.ulcerans_Agy99           QLNHERVALVSSAP-ISMALREVREWAQNTKDAGGARLIDSEWVQLNLAR
MAB_4158|M.abscessus_ATCC_1997      QLNHERVALVSSAP-IITALREVREWAQNTKGPGG-RIIDAEWVQLNLAR
Mflv_1551|M.gilvum_PYR-GCK          QLNHERVALVSAQP-IFVALNGVREWAQNTKDVHGNRVIDSEWVQLNLAR
Mvan_5206|M.vanbaalenii_PYR-1       QLNHERVALVSAQP-IFVALNGVREWAQNTKDVHGKRLIDSEWVQLNLAR
MSMEG_5906|M.smegmatis_MC2_155      QLNHERVALVSAQP-IYVALNGVREWAQNTKDVHGKRLIDSEWVQLNLAR
MLBr_00737|M.leprae_Br4923          TLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLAD
                                     *:  * ::      :      .     .     *  :     ::  ** 

TH_4647|M.thermoresistible__bu      VEAQVSAYRLMNLRVNAS---MSSGGLGM-AEASAAKVFGTELTQRVARE
MAV_1338|M.avium_104                VEAQVAAYKLVNLRVNAA---MTKGALNM-GEASAAKVFGTELTQQVARE
Mb3534|M.bovis_AF2122/97            VHAKAEVLKLINWELASSQSGPKDAGPSP-ADASAAKVFGTELATEAYRL
Rv3504|M.tuberculosis_H37Rv         VHAKAEVLKLINWELASSQSGPKDAGPSP-ADASAAKVFGTELATEAYRL
MMAR_4992|M.marinum_M               VHAKVEVLKLINWELASN-----DAAPSP-ADASAAKVFGTELATEAYRL
MUL_4067|M.ulcerans_Agy99           VHAKVEVLKLINWELASN-----DAAPSP-ADASAAKVFGTELATEAYRL
MAB_4158|M.abscessus_ATCC_1997      VHAKAEYLKLINWELAST----TDAAPSP-ADASATKVFGTELATEAYRL
Mflv_1551|M.gilvum_PYR-GCK          VHAKAEVLKLINWELASS----TDTAPSP-ADASAAKVFGTELATEAYRL
Mvan_5206|M.vanbaalenii_PYR-1       VHAKAEVLKLINWELASA----TDAAPSP-ADASAAKVYGTELATEAYRL
MSMEG_5906|M.smegmatis_MC2_155      VHAKAEVLKLINWELAS-----TEAAPSP-ADASAAKVYGTELATEAYRL
MLBr_00737|M.leprae_Br4923          MAMKVEAARLIVYAAAAR---AERGEPDLGFISAASKCFASDIAMEVTTD
                                    :  :.   :*:     :          .    ::*:* :.:::: ..   

TH_4647|M.thermoresistible__bu      LLEVLGADGTRKG--ADAPLRGELEHAYRLAVINTFGGGANELQRDIIAM
MAV_1338|M.avium_104                LLEVLDGNGVRRG--AEAPLRGALESAYRQAVINTFGGGANEIQRDIIAM
Mb3534|M.bovis_AF2122/97            LMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGM
Rv3504|M.tuberculosis_H37Rv         LMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGM
MMAR_4992|M.marinum_M               LMEVLGTAATLRQDSPGALLHGRVERMHRACLILTFGGGTNEVQRDIIGM
MUL_4067|M.ulcerans_Agy99           LMEVLGTAATLRQDSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGM
MAB_4158|M.abscessus_ATCC_1997      LMEVLGTAATLRQDSPGAQLRGRVERMHRACLILTFGGGTNEVQRDIIAM
Mflv_1551|M.gilvum_PYR-GCK          LMEVLGTAATLRTNSPGAVLRGRIERMHRSCLILTFGGGTNEIQRDIIGM
Mvan_5206|M.vanbaalenii_PYR-1       LMEVLGTAATLRTNSPGALLRGRIERMHRSCLILTFGGGTNEIQRDIIGM
MSMEG_5906|M.smegmatis_MC2_155      LMEVLGTSATLRGDTRGALLRGRVERFHRSALILTFGGGTNEIQRDIIGM
MLBr_00737|M.leprae_Br4923          AVQLFGG--------AGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSR
                                     ::::.                 :*   * . *  :  *:*::** ::. 

TH_4647|M.thermoresistible__bu      AGLGMPRAPRDLRATAS
MAV_1338|M.avium_104                AALGMPRAPRDLRAAN-
Mb3534|M.bovis_AF2122/97            VALGLPRANR-------
Rv3504|M.tuberculosis_H37Rv         VALGLPRANR-------
MMAR_4992|M.marinum_M               VALGLPRANR-------
MUL_4067|M.ulcerans_Agy99           VALGLPRANR-------
MAB_4158|M.abscessus_ATCC_1997      TALGQPAASR-------
Mflv_1551|M.gilvum_PYR-GCK          VALGLPRVNR-------
Mvan_5206|M.vanbaalenii_PYR-1       VALGLPRVNR-------
MSMEG_5906|M.smegmatis_MC2_155      VALGLPRVNR-------
MLBr_00737|M.leprae_Br4923          ALLR-------------
                                    . *