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TEAYIYEAIRTPRGKGRASGALHSVKPISLVVGLIDELRRRFPDLDEDRISDVVLGVVTPVGDQGMDIAR TAVTVAGLPDTVGGVQLNRFCGSGLDAVNVAAKAVRSGFDELVIAGGVESMSRVEMGSDRGAMAYDAATA YDNYFIPQGVAADLLATIEGYTREDVDAYAARSQRRAAEAWSGGYFAKSVVPVRDINGLTILDHDEHMRP DSTVEDLAKLAPAFAGIGEFGGFDAVAMQRYHWVEAINHVHTGGNSSGIVDGASLVLVGSEQAGAASGLT PRARIVSAATSGADPVLMFGGPIPAVRKALDLAGLTIDDIDLFEMNEAFAAIAIKIQQYFGIPDQKYNVN GGAIAMGHPLGATGAMLLGTVLDELERRGGRYGLITLCVAGGMGVATIIERV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2702 | - | - | 100% (403) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_0980 | - | e-173 | 74.56% (401) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_4185 | - | 8e-85 | 44.94% (405) | FadA6_4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0882 | fadA | 1e-174 | 74.56% (401) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_1691 | - | 1e-171 | 73.82% (401) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv0859 | fadA | 1e-173 | 74.31% (401) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_02162 | fadA | 1e-170 | 72.32% (401) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0850 | - | 1e-171 | 72.70% (403) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_4677 | fadA | 1e-170 | 72.82% (401) | acyl-CoA thiolase FadA |
| M. smegmatis MC2 155 | MSMEG_5721 | - | 1e-173 | 74.56% (401) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0255 | - | 2e-73 | 42.08% (404) | acetyl-CoA acetyltransferase |
| M. ulcerans Agy99 | MUL_0296 | fadA | 1e-169 | 72.57% (401) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5067 | - | 1e-169 | 73.32% (401) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1691|M.gilvum_PYR-GCK --------------MSEEAFIYEAIRTPRGKQRG-GALNEIKPVNLVVGL
MSMEG_5721|M.smegmatis_MC2_155 --------------MSEEAFIYEAIRTPRGKQRG-GALNEIKPVNLVVGL
Mvan_5067|M.vanbaalenii_PYR-1 --------------MSEEAFIYEAIRTPRGKQRN-GALNEIKPVNLVVGL
MAB_0850|M.abscessus_ATCC_1997 ---------------MTEAFIYEAVRTPRGKQRG-GALNEIKPLNLVVGL
Mb0882|M.bovis_AF2122/97 --------------MSEEAFIYEAIRTPRGKQKN-GSLHEVKPLSLVVGL
Rv0859|M.tuberculosis_H37Rv --------------MSEEAFIYEAIRTPRGKQKN-GSLHEVKPLSLVVGL
MLBr_02162|M.leprae_Br4923 --------------MSEEAFIYEAIRTPRGKQKN-GSLHEVKPVSLVVGL
MMAR_4677|M.marinum_M MTDLNPNFCEQEVDMSEEAFIYEAIRTPRGKQKN-GSLNEVKPISLVVGL
MUL_0296|M.ulcerans_Agy99 --------------MSEEAFIYEAIRTPRGKQKY-GSLNEVKPISLVVGL
MAV_2702|M.avium_104 ---------------MTEAYIYEAIRTPRGKGRASGALHSVKPISLVVGL
TH_0255|M.thermoresistible__bu ---------------MRETVIVEAVRTAVGKRNG--ALADVHAADLSAVV
*: * **:**. ** . :* .::. .* . :
Mflv_1691|M.gilvum_PYR-GCK IDEMRTRFPDLDENLISDLILGVVSPVGDQGGDIARTAGLVAKLPETTGG
MSMEG_5721|M.smegmatis_MC2_155 IDELRVRFPNLDETLISDLVLGVVSPVGDQGGDIARTATLVANLPETTGG
Mvan_5067|M.vanbaalenii_PYR-1 IDEMRVRFPDLDENLISDLILGCVSPVGDQGGDIARTAGLVAGLPDTTGG
MAB_0850|M.abscessus_ATCC_1997 IEEIRHRHPDLDENLISDVVLGVVSPVGDQGGDIARTAVLAAGLPDTTGG
Mb0882|M.bovis_AF2122/97 IDELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGG
Rv0859|M.tuberculosis_H37Rv IDELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGG
MLBr_02162|M.leprae_Br4923 VEELRKRNPDLDENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGG
MMAR_4677|M.marinum_M IEELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGG
MUL_0296|M.ulcerans_Agy99 IEELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGG
MAV_2702|M.avium_104 IDELRRRFPDLDEDRISDVVLGVVTPVGDQGMDIARTAVTVAGLPDTVGG
TH_0255|M.thermoresistible__bu LSELVER-AGIDPELIDDVIWGCVSQVGDQSSNIGRYAVLAAGWPETIPG
:.*: * ..:* *.*:: * *: ****. :*.* : .: * * *
Mflv_1691|M.gilvum_PYR-GCK VQLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
MSMEG_5721|M.smegmatis_MC2_155 VQLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
Mvan_5067|M.vanbaalenii_PYR-1 FQLNRFCASGLEAVNLGAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
MAB_0850|M.abscessus_ATCC_1997 VQLNRFCASGLEAINIGAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
Mb0882|M.bovis_AF2122/97 VQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
Rv0859|M.tuberculosis_H37Rv VQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
MLBr_02162|M.leprae_Br4923 VQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GG
MMAR_4677|M.marinum_M VQLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGAD---GG
MUL_0296|M.ulcerans_Agy99 VQLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGAD---GG
MAV_2702|M.avium_104 VQLNRFCGSGLDAVNVAAKAVRSGFDELVIAGGVESMSRVEMGSD---RG
TH_0255|M.thermoresistible__bu TTVNRACGSSQQALDFAVHAVMSGQQDVVVAGGVEVMSRVPLGAARATGM
:** *.*. :*:: ..: * ** :::*:***** **** :*:
Mflv_1691|M.gilvum_PYR-GCK AWAADPETNYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQERAAAAW
MSMEG_5721|M.smegmatis_MC2_155 AWAGDPETNYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQERAAAAW
Mvan_5067|M.vanbaalenii_PYR-1 AWAGDPETNYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQERAAAAW
MAB_0850|M.abscessus_ATCC_1997 AWASDPATNYDVSFVPQGIGADLIATIEGFTRDDVDAYAARSQERAAAAW
Mb0882|M.bovis_AF2122/97 AMGLDPATNYDVMFVPQGIGADLIATIEGFSREDVDAYALRSQQKAAEAW
Rv0859|M.tuberculosis_H37Rv AMGLDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQQKAAEAW
MLBr_02162|M.leprae_Br4923 AMGLDPATNYDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAW
MMAR_4677|M.marinum_M AMGLDPVTNYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQEKAAEAW
MUL_0296|M.ulcerans_Agy99 AMGLDPVTNYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQEKAAEAW
MAV_2702|M.avium_104 AMAYDAATAYDNYFIPQGVAADLLATIEGYTREDVDAYAARSQRRAAEAW
TH_0255|M.thermoresistible__bu PYGPKVLERYDNFGFNQGISAELIAERWNLSRTRLDEYSAQSHERAAAAQ
. . . * . *.:.*:*:* . :* :* *: :*:.:** *
Mflv_1691|M.gilvum_PYR-GCK SGGYFAKSVVPVKDQNGLVVLDHDEHIRPGTTIESLGKLKSAFEGVGAMG
MSMEG_5721|M.smegmatis_MC2_155 SGGYFSKSVVPVKDQNGLVVLDHDEHMRPGTTVESLGKLKPAFEGVGAMG
Mvan_5067|M.vanbaalenii_PYR-1 AGGYFAKSVVPVKDQNGLVVLDHDEHMRPGSTVESLGKLKTAFDGIGAMG
MAB_0850|M.abscessus_ATCC_1997 SGGYFAKSVVPVKDQNGLLVLDHDEHMRPGTTAADLGKLKPAFEGLAALG
Mb0882|M.bovis_AF2122/97 SGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALG
Rv0859|M.tuberculosis_H37Rv SGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALG
MLBr_02162|M.leprae_Br4923 SGGYFAKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLKPAFEGLAAMG
MMAR_4677|M.marinum_M SGGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAFEGLAAMG
MUL_0296|M.ulcerans_Agy99 SGGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAFEGLAAMG
MAV_2702|M.avium_104 SGGYFAKSVVPVRDINGLTILDHDEHMRPDSTVEDLAKLAPAFAGIGEFG
TH_0255|M.thermoresistible__bu SSGAFKDQIVPVFTDD--AVVTEDEGIRRGTTVEKLATLKPAFT------
:.* * ..:*** : :: .** :* :: *..* .**
Mflv_1691|M.gilvum_PYR-GCK GFDDVALQKYHFVEKINHVHTGGNSSGIVDGAALVLIGSESAGTSQGLTP
MSMEG_5721|M.smegmatis_MC2_155 GFDDVALQKYHSIEKINHVHTGGNSSGIVDGAALVLIGSESAGKAAGLTP
Mvan_5067|M.vanbaalenii_PYR-1 GFDDVALQKYHFVEKINHVHTGGNSSGIVDGAALLLIGSEAAGKSQGLTP
MAB_0850|M.abscessus_ATCC_1997 GFDDVARIKYHYVEKINHVHTGGNSSGIVDGAALVLIGSEEAGKSQGLTP
Mb0882|M.bovis_AF2122/97 GFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTP
Rv0859|M.tuberculosis_H37Rv GFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTP
MLBr_02162|M.leprae_Br4923 GFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLTP
MMAR_4677|M.marinum_M GFDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAGAAINATP
MUL_0296|M.ulcerans_Agy99 GFDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAGAAINATP
MAV_2702|M.avium_104 GFDAVAMQRYHWVEAINHVHTGGNSSGIVDGASLVLVGSEQAGAASGLTP
TH_0255|M.thermoresistible__bu ---------------ENGVIHAGNSSQISDGAAALLVMTAETAVTLGLTP
* * .**** * ***: ::: : .. . **
Mflv_1691|M.gilvum_PYR-GCK RARIVATATSGADPVIMLTGPTPATKKVLDRAGLTVDDIDLFELNEAFAS
MSMEG_5721|M.smegmatis_MC2_155 RARVVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFAS
Mvan_5067|M.vanbaalenii_PYR-1 RARIVATATSGADPVIMLTGPTPATQKVLDRAGLTVDDIDLFELNEAFAS
MAB_0850|M.abscessus_ATCC_1997 RARIVATATSGSEPLIMLTGPTPATKKVLDRAGLTVDDIDLFELNEAFAS
Mb0882|M.bovis_AF2122/97 RARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFAS
Rv0859|M.tuberculosis_H37Rv RARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFAS
MLBr_02162|M.leprae_Br4923 RARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFAS
MMAR_4677|M.marinum_M RARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFELNEAFAS
MUL_0296|M.ulcerans_Agy99 RARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFELNEAFAS
MAV_2702|M.avium_104 RARIVSAATSGADPVLMFGGPIPAVRKALDLAGLTIDDIDLFEMNEAFAA
TH_0255|M.thermoresistible__bu IVRYRAGAVTGADPVLMLTGPIPATEKVLRKTGLNIDDIGVFEVNEAFAP
.* : *.:*::*::*: ** **..*.* :**.:***.:**:*****.
Mflv_1691|M.gilvum_PYR-GCK VVLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGAR
MSMEG_5721|M.smegmatis_MC2_155 VVLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGAR
Mvan_5067|M.vanbaalenii_PYR-1 VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGAK
MAB_0850|M.abscessus_ATCC_1997 VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGLK
Mb0882|M.bovis_AF2122/97 VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNAR
Rv0859|M.tuberculosis_H37Rv VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNAR
MLBr_02162|M.leprae_Br4923 VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERCNAR
MMAR_4677|M.marinum_M VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNAR
MUL_0296|M.ulcerans_Agy99 VVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNAR
MAV_2702|M.avium_104 IAIKIQQYFGIPDQKYNVNGGAIAMGHPLGATGAMLLGTVLDELERRGGR
TH_0255|M.thermoresistible__bu VPLAWQAETGADPAKLNPLGGAIALGHPLGASGAVLMTRMVHHMRANGIR
: : * . * * *****:******:**:: ::..:. . :
Mflv_1691|M.gilvum_PYR-GCK RALITLCVGGGMGVATIIERV-
MSMEG_5721|M.smegmatis_MC2_155 RALITLCVGGGMGVATIIERV-
Mvan_5067|M.vanbaalenii_PYR-1 RALMTLCVGGGMGVATIIERV-
MAB_0850|M.abscessus_ATCC_1997 RALITLCVGGGMGVATIIERV-
Mb0882|M.bovis_AF2122/97 RALITLCIGGGMGVATIIERV-
Rv0859|M.tuberculosis_H37Rv RALITLCIGGGMGVATIIERV-
MLBr_02162|M.leprae_Br4923 RALVTLCIGAGMGVATIIERV-
MMAR_4677|M.marinum_M RALVTLCIGGGMGVATIIERV-
MUL_0296|M.ulcerans_Agy99 RALVTLCIGGGMGAATIIERV-
MAV_2702|M.avium_104 YGLITLCVAGGMGVATIIERV-
TH_0255|M.thermoresistible__bu YGLQTMCEGGGTANATVVELLA
.* *:* ..* . **::* :