For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSTAAVTLATTIPGEHVRIAVNKDTEPFWIAAKERRLVAPQCGDCQTFRLPPTPFCPNCQSNAVNWVELS GQAVVYSFAVVHGFPGMPDLLLVPAVLDLPDAPGARLVSNIVDVAPADITIGMSVHVDFSPITDGWMLPV FRAAASPNAKE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2631 | - | - | 100% (151) | hypothetical protein MAV_2631 |
| M. avium 104 | MAV_1919 | - | 2e-71 | 84.11% (151) | acyl dehydratase |
| M. avium 104 | MAV_5258 | - | 8e-15 | 31.93% (119) | hypothetical protein MAV_5258 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 2e-08 | 32.28% (127) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 4e-17 | 38.10% (126) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 2e-08 | 32.28% (127) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2052 | - | 4e-08 | 30.40% (125) | hypothetical protein MAB_2052 |
| M. marinum M | MMAR_4248 | - | 5e-18 | 37.40% (131) | hypothetical protein MMAR_4248 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 1e-15 | 36.76% (136) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4577 | - | 4e-67 | 77.40% (146) | PUTATIVE acyl dehydratase |
| M. ulcerans Agy99 | MUL_0937 | - | 8e-17 | 36.64% (131) | hypothetical protein MUL_0937 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 1e-15 | 37.10% (124) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3572c|M.bovis_AF2122/97 MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
Rv3542c|M.tuberculosis_H37Rv MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
Rv3542c|M.tuberculosis_H37Rv DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
Rv3542c|M.tuberculosis_H37Rv GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
Rv3542c|M.tuberculosis_H37Rv QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
MMAR_4248|M.marinum_M -------------------------------MASRLAPAISPDTEFFWHG
MUL_0937|M.ulcerans_Agy99 -------------------------------MASRLAPAISPDTEFFWHG
MAB_2052|M.abscessus_ATCC_1997 -------------------MTAASSSLDGLHDPEALPPLTDVNRPYFAAA
MAV_2631|M.avium_104 -------------------MSTAAVTLATTIPGEHVRIAVNKDTEPFWIA
TH_4577|M.thermoresistible__bu -------------------MSTAEATLATTMPGEHVRIAVNNHTEPFWQA
Mflv_2483|M.gilvum_PYR-GCK ---------------------------MSRLP---LPLLTFDN-EFFWTS
Mvan_4171|M.vanbaalenii_PYR-1 ---------------------------MSRLP---LPQLTFDN-EFFWKS
MSMEG_4814|M.smegmatis_MC2_155 ---------------------------MSQIPGRPLPTVTALN-EYFWTA
: . * .
Mb3572c|M.bovis_AF2122/97 VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
Rv3542c|M.tuberculosis_H37Rv VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
MMAR_4248|M.marinum_M LREHKLLIQRCAECGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVMP
MUL_0937|M.ulcerans_Agy99 LREHQLLIQRCAEFGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVMP
MAB_2052|M.abscessus_ATCC_1997 ARG-VLVFQRCAN-GHPFLYPRLVCPVCHDGELAWETAAGTGEIVSFAPV
MAV_2631|M.avium_104 AKERRLVAPQCGDCQTFRLPPTPFCPNCQSNAVNWVELSGQAVVYSFAVV
TH_4577|M.thermoresistible__bu AKQRRLVAPQCADCGVFRMPPTPFCPGCQSKAVNWVELSGEATLYSFAVV
Mflv_2483|M.gilvum_PYR-GCK GADGVLRIQECGDCKSLIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVN
Mvan_4171|M.vanbaalenii_PYR-1 GADGVLRIQECGDCKALIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVN
MSMEG_4814|M.smegmatis_MC2_155 GRDGVLRIQECRSCDALIHPPQPICRYCRSHDLGVRDVSGRATLAGFTVN
* . . * : .* . : .*.
Mb3572c|M.bovis_AF2122/97 HAPKVP---GRTVPFVIALVELEEGVRMLGELRGADPARVAIGMPVRATY
Rv3542c|M.tuberculosis_H37Rv HAPKVP---GRTVPFVIALVELEEGVRMLGELRGADPARVAIGMPVRATY
MMAR_4248|M.marinum_M HQPRFP---FFDYPYIVVLVELDEGVRLVSNLCGIDPADVTVGMAVEVFY
MUL_0937|M.ulcerans_Agy99 HQPRFP---FFDYPYIVVLVELDEGVRLVSNLCGIDPADVTVGMAVEVFY
MAB_2052|M.abscessus_ATCC_1997 YRPPWDSF-PRSEPYVVVLVRLDEGPQLLASLEGVAPDEVAIGARVRAVF
MAV_2631|M.avium_104 H--GFPGMPDLLLVPAVLDLPDAPGARLVSNIVDVAPADITIGMSVHVDF
TH_4577|M.thermoresistible__bu H--GIPELPELTLVPVVVDLPDAPGARLVSNVVDIAPADVTIGMMLRVDF
Mflv_2483|M.gilvum_PYR-GCK HRFSIPGLEAPYVVAQVAIE-EDPRVRLTTNIVDCDPDELELGRVVEVVF
Mvan_4171|M.vanbaalenii_PYR-1 HRFSIPGLQAPYVVAQVAIE-EDPRVRLTTNIIDCDPDELELGRVVEVVF
MSMEG_4814|M.smegmatis_MC2_155 ERFGFPDMPPPYVVAEVAIV-EDPRVRLTTNIVDCDPQSLELGQPVEVSF
: :: .: . * : :* :.. :
Mb3572c|M.bovis_AF2122/97 IDF--PD--WSLYAWEPDE-------------------------------
Rv3542c|M.tuberculosis_H37Rv IDF--PD--WSLYAWEPDE-------------------------------
MMAR_4248|M.marinum_M QDFDGPDGSFVLHQFRPVALDSEAVR------------------------
MUL_0937|M.ulcerans_Agy99 QDFDGPDGSFVLHQFRPVALDSEAVR------------------------
MAB_2052|M.abscessus_ATCC_1997 ERVN---EDLGLVRFRPAAS------------------------------
MAV_2631|M.avium_104 SPITDG---WMLPVFRAAASPNAKE-------------------------
TH_4577|M.thermoresistible__bu SPIADG---WMLPIFRPAVSSIERKNNDQ---------------------
Mflv_2483|M.gilvum_PYR-GCK EQNED----VWLPLFRPTAEPETAALPDDEIAPQEFPKFVRPMLTTEKFE
Mvan_4171|M.vanbaalenii_PYR-1 EENDD----VWLPLFRPTAETETAPLPEDEIAPQDFGKFVRPMLTTEKFE
MSMEG_4814|M.smegmatis_MC2_155 QHIDD----VWLPVFTPSADTTPTPAPVEDIAPQDIGKFVRPMLTEDKFE
* : .
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK DAAAITGIGASKMGRRLMVSPLSLTVEACEKAIADAGLTLADIDGLSTYP
Mvan_4171|M.vanbaalenii_PYR-1 DAAAITGIGASRMGRRLMVSPLSLTVEACEAAIADAGLTLADIDGLSTYP
MSMEG_4814|M.smegmatis_MC2_155 DHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAVADAGLTFDDIDGLSTYP
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK AMDAMGMGEGGCTVLEGALGIRPTWINGGMDTFGPGGSLIAAVMAVATGM
Mvan_4171|M.vanbaalenii_PYR-1 AMDAMGMGEGGVTALEGALGIRPTWINGGMDTFGPGGSVIAAVMAVATGM
MSMEG_4814|M.smegmatis_MC2_155 GLDIAGMGEGGVSVLEGALGLRPTWINGGMDTFGPGGSVIAAMMAISAGL
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK ARHVLCFRTLWEATFNQLMKEGKASPPGGARVNSWQAPFGATSAAHTLAL
Mvan_4171|M.vanbaalenii_PYR-1 ARHVLCFRTLWEATFNQLMKEGRVSPPGGTRVNSWQAPFGATSAAHTLAL
MSMEG_4814|M.smegmatis_MC2_155 ARHVLCFRTLWEATFGQLVKEGKMSPPMSARTNSWQQPYGATSAAHTLAQ
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK NAQRHFHRYGTTKETLGWIALNQRANAALNPTAIYRDPMTMQDYLNARPI
Mvan_4171|M.vanbaalenii_PYR-1 NAQRHFHRYGTTKETLGWIALNQRANAALNPTAIYRDPMTMDDYLNARPI
MSMEG_4814|M.smegmatis_MC2_155 NAGRHFHRYGTTRETLGWIALNQRANAALNPTAIYREPLTMEDYLSARTI
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TTPFGLYDCDVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIERTDW
Mvan_4171|M.vanbaalenii_PYR-1 TTPFGLYDCDVPCDGAVAVVVSAVDAAVDLPKPPVYFEAVGTQIIERTDW
MSMEG_4814|M.smegmatis_MC2_155 TTPFGLYDCDVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIERLDW
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK DQTTLTHEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALG
Mvan_4171|M.vanbaalenii_PYR-1 DQTTLTHEPQVLGQAAHLWTRTSLRPADVDVAELYDGFTFNCLSWLEALG
MSMEG_4814|M.smegmatis_MC2_155 DQTTLTHEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGLG
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2631|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK FCGIGESKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVSQL
Mvan_4171|M.vanbaalenii_PYR-1 FCGIGEAKDFLDGGKAIARDGVIPLNTHGGQLSHGRTHGMGLIHEAVSQL
MSMEG_4814|M.smegmatis_MC2_155 FCGIGEAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQL
Mb3572c|M.bovis_AF2122/97 ----------------------------------
Rv3542c|M.tuberculosis_H37Rv ----------------------------------
MMAR_4248|M.marinum_M ----------------------------------
MUL_0937|M.ulcerans_Agy99 ----------------------------------
MAB_2052|M.abscessus_ATCC_1997 ----------------------------------
MAV_2631|M.avium_104 ----------------------------------
TH_4577|M.thermoresistible__bu ----------------------------------
Mflv_2483|M.gilvum_PYR-GCK RGEAGERQVADARVAVVSSGGLTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 RGEAGERQVDGARVAVVSSGGLTPSGALLLRTAT
MSMEG_4814|M.smegmatis_MC2_155 RGEAGERQVEDARVAVASSGGLTPSGVLLLRRDD