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MSTAAAILATTIPGEHVRIAVNKDTEPFWQAAKERRLVAPQCADCQTFRLPPTPFCPTCQSKAVNWVELS GAATVYSFAVVHGVPGMPDLVLVPAVLDLADAPGARLVSNVVDVAPADVFIGMSLRVDFSPIADGWLLPI FRVDQSAKE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1919 | - | - | 100% (149) | acyl dehydratase |
| M. avium 104 | MAV_2631 | - | 2e-71 | 84.11% (151) | hypothetical protein MAV_2631 |
| M. avium 104 | MAV_5258 | - | 3e-15 | 32.77% (119) | hypothetical protein MAV_5258 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 2e-10 | 33.58% (134) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 1e-13 | 33.88% (121) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 2e-10 | 33.58% (134) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0616 | - | 6e-07 | 31.67% (120) | hypothetical protein MAB_0616 |
| M. marinum M | MMAR_4248 | - | 8e-18 | 38.28% (128) | hypothetical protein MMAR_4248 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 1e-13 | 34.85% (132) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4577 | - | 2e-68 | 80.54% (149) | PUTATIVE acyl dehydratase |
| M. ulcerans Agy99 | MUL_0937 | - | 1e-16 | 37.50% (128) | hypothetical protein MUL_0937 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 3e-13 | 33.06% (121) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIG
Rv3542c|M.tuberculosis_H37Rv --------MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIG
MAB_0616|M.abscessus_ATCC_1997 --------MS-VVDIQEGFAKIKADGPSAPRLARDPVNQAMINNWVEAMG
MAV_1919|M.avium_104 MSTAAAILATTIPGEHVRIAVNKDTEPFWQAAKERRLVAPQCADCQTFRL
TH_4577|M.thermoresistible__bu MSTAEATLATTMPGEHVRIAVNNHTEPFWQAAKQRRLVAPQCADCGVFRM
Mflv_2483|M.gilvum_PYR-GCK --------MSRLP---LPLLTFDN-EFFWTSGADGVLRIQECGDCKSLIH
Mvan_4171|M.vanbaalenii_PYR-1 --------MSRLP---LPQLTFDN-EFFWKSGADGVLRIQECGDCKALIH
MSMEG_4814|M.smegmatis_MC2_155 --------MSQIPGRPLPTVTALN-EYFWTAGRDGVLRIQECRSCDALIH
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 DRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIK
Rv3542c|M.tuberculosis_H37Rv DRNPIYVDDAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIK
MAB_0616|M.abscessus_ATCC_1997 DRNPIYVDEEAAKAAGHPGIVAPPAMAQVWTMAGLYGERSGDDPLGRVMA
MAV_1919|M.avium_104 PPTPFCPTCQSKAVNWVE--LSGAATVYSFAVVH--GVPGMPDLVLVPAV
TH_4577|M.thermoresistible__bu PPTPFCPGCQSKAVNWVE--LSGEATLYSFAVVH--GIPELPELTLVPVV
Mflv_2483|M.gilvum_PYR-GCK PPQPVCRYCHSHNMGPRE--VSGRAVLSAFTVNHRFSIPGLEAP-YVVAQ
Mvan_4171|M.vanbaalenii_PYR-1 PPQPVCRYCHSHNMGPRE--VSGRAVLSAFTVNHRFSIPGLQAP-YVVAQ
MSMEG_4814|M.smegmatis_MC2_155 PPQPICRYCRSHDLGVRD--VSGRATLAGFTVNERFGFPDMPPP-YVVAE
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 LFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGW
Rv3542c|M.tuberculosis_H37Rv LFDDAGYIGVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGW
MAB_0616|M.abscessus_ATCC_1997 LLDSAGYESVVATNYEQIYHRYLELGEQVTTTNEVTEVFGPKQTALGESW
MAV_1919|M.avium_104 LDLADAPGARLVSNVVDVAPADVFIGMSLRVDFSPIADGWLLPIFRVDQS
TH_4577|M.thermoresistible__bu VDLPDAPGARLVSNVVDIAPADVTIGMMLRVDFSPIADGWMLPIFRPAVS
Mflv_2483|M.gilvum_PYR-GCK VAIEEDPRVRLTTNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEP
Mvan_4171|M.vanbaalenii_PYR-1 VAIEEDPRVRLTTNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAET
MSMEG_4814|M.smegmatis_MC2_155 VAIVEDPRVRLTTNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADT
MMAR_4248|M.marinum_M ----------------------------------------MA--SRLAPA
MUL_0937|M.ulcerans_Agy99 ----------------------------------------MA--SRLAPA
Mb3572c|M.bovis_AF2122/97 FINQHIVWQVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPD--AMMRPS
Rv3542c|M.tuberculosis_H37Rv FINQHIVWQVGDEDVAEMNWRILKFKP-AGSPSSVPDDLDPD--AMMRPS
MAB_0616|M.abscessus_ATCC_1997 FINIHAEWHVGDELVNEMNWRIMKFRPGAKKAADVPQDLDPS--KLMRPS
MAV_1919|M.avium_104 AKE-----------------------------------------------
TH_4577|M.thermoresistible__bu SIERKNNDQ-----------------------------------------
Mflv_2483|M.gilvum_PYR-GCK ETAALPDDEIAPQEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSP
Mvan_4171|M.vanbaalenii_PYR-1 ETAPLPEDEIAPQDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSP
MSMEG_4814|M.smegmatis_MC2_155 TPTPAPVEDIAPQDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPP
MMAR_4248|M.marinum_M ISPDTEFFWHGLREHKLLIQRCAECGELRHPPRPMCPKCRCLHWDTVE--
MUL_0937|M.ulcerans_Agy99 ISPDTEFFWHGLREHQLLIQRCAEFGELRHPPRPMCPKCRCLHWDTVE--
Mb3572c|M.bovis_AF2122/97 SSRDTAFFWDGVKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVV--
Rv3542c|M.tuberculosis_H37Rv SSRDTAFFWDGVKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVV--
MAB_0616|M.abscessus_ATCC_1997 WSRDSAYFWEGVAAHELRLQKRPD-GSLQHPPVPAVWQDKEAPIEYQV--
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK LSLTVEACEKAIADAGLTLADIDGLSTYPAMDAMGMGEGGCTVLEGALGI
Mvan_4171|M.vanbaalenii_PYR-1 LSLTVEACEAAIADAGLTLADIDGLSTYPAMDAMGMGEGGVTALEGALGI
MSMEG_4814|M.smegmatis_MC2_155 LSLTIEAAEQAVADAGLTFDDIDGLSTYPGLDIAGMGEGGVSVLEGALGL
MMAR_4248|M.marinum_M ---------------SGGLGTVYSFVMPHQPRFPFFDYPYIVVLVELDEG
MUL_0937|M.ulcerans_Agy99 ---------------SGGLGTVYSFVMPHQPRFPFFDYPYIVVLVELDEG
Mb3572c|M.bovis_AF2122/97 ---------------SSGRGTVFSFVVHHAPKVPGRTVPFVIALVELEEG
Rv3542c|M.tuberculosis_H37Rv ---------------SSGRGTVFSFVVHHAPKVPGRTVPFVIALVELEEG
MAB_0616|M.abscessus_ATCC_1997 ---------------ASGRGTVYSYVVHHAPQVPGRTLPFVIALVELDEG
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK RPTWINGGMDTFGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKE
Mvan_4171|M.vanbaalenii_PYR-1 RPTWINGGMDTFGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKE
MSMEG_4814|M.smegmatis_MC2_155 RPTWINGGMDTFGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKE
MMAR_4248|M.marinum_M ----------VRLVSNLCGIDPADVTVGMAVEVFYQDFDGP--DGSFVLH
MUL_0937|M.ulcerans_Agy99 ----------VRLVSNLCGIDPADVTVGMAVEVFYQDFDGP--DGSFVLH
Mb3572c|M.bovis_AF2122/97 ----------VRMLGELRGADPARVAIGMPVRATYIDFPD------WSLY
Rv3542c|M.tuberculosis_H37Rv ----------VRMLGELRGADPARVAIGMPVRATYIDFPD------WSLY
MAB_0616|M.abscessus_ATCC_1997 ----------VRMLGELRGVSPDDVQIGLPVRATYLDFPAEGEDPAWTLY
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK GKASPPGGARVNSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIAL
Mvan_4171|M.vanbaalenii_PYR-1 GRVSPPGGTRVNSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIAL
MSMEG_4814|M.smegmatis_MC2_155 GKMSPPMSARTNSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIAL
MMAR_4248|M.marinum_M QFRPVALDSEAVR-------------------------------------
MUL_0937|M.ulcerans_Agy99 QFRPVALDSEAVR-------------------------------------
Mb3572c|M.bovis_AF2122/97 AWEPDE--------------------------------------------
Rv3542c|M.tuberculosis_H37Rv AWEPDE--------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 AWEAA---------------------------------------------
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK NQRANAALNPTAIYRDPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIV
Mvan_4171|M.vanbaalenii_PYR-1 NQRANAALNPTAIYRDPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVV
MSMEG_4814|M.smegmatis_MC2_155 NQRANAALNPTAIYREPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIV
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK SAVDAAADAPKPPVFFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTR
Mvan_4171|M.vanbaalenii_PYR-1 SAVDAAVDLPKPPVYFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTR
MSMEG_4814|M.smegmatis_MC2_155 SAVDAARDLPRPPIRFEAVGTQIIERLDWDQTTLTHEPQVLGQSAHMWSR
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TSLRPDDVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDG
Mvan_4171|M.vanbaalenii_PYR-1 TSLRPADVDVAELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDG
MSMEG_4814|M.smegmatis_MC2_155 TSLRPSDVDVAELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDG
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1919|M.avium_104 --------------------------------------------------
TH_4577|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK VIPLNTHGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVADARVAVVSSGG
Mvan_4171|M.vanbaalenii_PYR-1 VIPLNTHGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVDGARVAVVSSGG
MSMEG_4814|M.smegmatis_MC2_155 IIPLNTHGGQLSHGRTHGMGLIHEAVTQLRGEAGERQVEDARVAVASSGG
MMAR_4248|M.marinum_M -------------
MUL_0937|M.ulcerans_Agy99 -------------
Mb3572c|M.bovis_AF2122/97 -------------
Rv3542c|M.tuberculosis_H37Rv -------------
MAB_0616|M.abscessus_ATCC_1997 -------------
MAV_1919|M.avium_104 -------------
TH_4577|M.thermoresistible__bu -------------
Mflv_2483|M.gilvum_PYR-GCK LTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 LTPSGALLLRTAT
MSMEG_4814|M.smegmatis_MC2_155 LTPSGVLLLRRDD