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VTAAPARHRPMSVIPAPPRLARLSITLHRLVAGWNRLGSQTAFYVKALSLMWDAVARYKAETLRLIATMS LGVGALAVIGGTVVVVTTLVMSTGSFIGIQLYRSLSDVGVEALSGFASAYLNTRFAAPLTSAIGLAATIG AGATAQLGAMRINEEIDALEVMGIRAISYLASTRIVAGVLVTVPLWCLSSLAGYLATRTLVVVAFGQAPG VYDHYFNTYLQPTDLIWSLLQVMATATVVMLVHTYYGFNATGGPAGVGEAVGRSVRASLVVAVTVQLAVA MAAYGVSGNFNLSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2531 | - | - | 100% (294) | TrnB2 protein |
| M. avium 104 | MAV_2060 | - | 4e-92 | 58.99% (278) | TrnB2 protein |
| M. avium 104 | MAV_0656 | - | 2e-81 | 55.64% (257) | ABC-transporter integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3530c | yrbE4B | 3e-82 | 54.14% (266) | integral membrane protein YrbE4b |
| M. gilvum PYR-GCK | Mflv_2100 | - | 1e-89 | 60.15% (261) | hypothetical protein Mflv_2100 |
| M. tuberculosis H37Rv | Rv1965 | yrbE3B | 2e-85 | 58.71% (264) | integral membrane protein YrbE3b |
| M. leprae Br4923 | MLBr_02588 | yrbE1B | 8e-72 | 47.67% (279) | hypothetical protein MLBr_02588 |
| M. abscessus ATCC 19977 | MAB_4154c | - | 5e-84 | 56.32% (261) | hypothetical protein MAB_4154c |
| M. marinum M | MMAR_2881 | yrbE3B | 2e-88 | 59.19% (272) | integral membrane protein, YrbE3B |
| M. smegmatis MC2 155 | MSMEG_0345 | - | 3e-90 | 57.72% (272) | hypothetical protein MSMEG_0345 |
| M. thermoresistible (build 8) | TH_0168 | - | 1e-93 | 59.27% (275) | TrnB2 protein |
| M. ulcerans Agy99 | MUL_3917 | yrbE3B_1 | 3e-88 | 58.33% (264) | integral membrane protein YrbE3B_1 |
| M. vanbaalenii PYR-1 | Mvan_0921 | - | 9e-96 | 61.23% (276) | hypothetical protein Mvan_0921 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3530c|M.bovis_AF2122/97 --------MS------YDVTIRFRRFFSRLQRPVDNFGEQALFYGETMRY
MAB_4154c|M.abscessus_ATCC_199 --------MSGPYLSTHTVTSYTVRYMRGLGRSFDKFGEQALFYAQSLSY
TH_0168|M.thermoresistible__bu -------------------MPRIRRTADKVLDSLARLGDQAQFYGRTFGS
Mvan_0921|M.vanbaalenii_PYR-1 ----------MTSSAPSTRAPRLRRTVVGLAAGWNRIGTQTEFYGRTVRS
Mflv_2100|M.gilvum_PYR-GCK ----------MTVSRPHSQFPWLKARFRSIADPWNQVGVQTKFYGRTLRS
MUL_3917|M.ulcerans_Agy99 ----------MTAVAAGSRWRGVRHKLDGWVAGWNQIGTQTKFFGRTLRS
MSMEG_0345|M.smegmatis_MC2_155 ----------------------MSNRLDRVRAAWDGIGVQTQFYARAIGS
Rv1965|M.tuberculosis_H37Rv ----------MTA-------------AKALVSEWNRMGSQMRFFVGTLAG
MMAR_2881|M.marinum_M ----------MTVSASRSSRHRLRRTAKSLVREWNRLGSQMRFYVTTLTG
MAV_2531|M.avium_104 MTAAPARHRPMSVIPAPPRLARLSITLHRLVAGWNRLGSQTAFYVKALSL
MLBr_02588|M.leprae_Br4923 -----MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIALGN
.* * :.
Mb3530c|M.bovis_AF2122/97 VPNAITRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIAVQ
MAB_4154c|M.abscessus_ATCC_199 IPAALTKYRKETIRVLAEITMGTGALVMIGGTVGVAVFLTLASGGVIAVQ
TH_0168|M.thermoresistible__bu IGEAFVHYKVEVVRLIAQMSLGVGALAVIGGTIVIVAFLTLSTGALVAVQ
Mvan_0921|M.vanbaalenii_PYR-1 IGDAVVHYRTEIAVQIAQMSLGTGALAVVGGTIVIVGFLTMSAGALIAVQ
Mflv_2100|M.gilvum_PYR-GCK IVIAVTRYRIELVRQIAQMGLGAGALIVIGGTVAIVGFLTVTTGALVAVQ
MUL_3917|M.ulcerans_Agy99 IHYMLIHYRVELIRLIAQMGLGAGALMVIGGTVAIVGFLTVTTGALVAVQ
MSMEG_0345|M.smegmatis_MC2_155 IGDAAMNYRTELIRLIATMGLGAGALAVVGGTVAIVGFLTMTTGALVAVQ
Rv1965|M.tuberculosis_H37Rv IPDALMHYRGELLRVIAQMGLGTGVLAVIGGTVAIVGFLAMTTGAIVAVQ
MMAR_2881|M.marinum_M IPDAVMHYRSELLRVIAQMGFGAGTLAVIGGTVVIVGFLAMTTGAIVAVQ
MAV_2531|M.avium_104 MWDAVARYKAETLRLIATMSLGVGALAVIGGTVVVVTTLVMSTGSFIGIQ
MLBr_02588|M.leprae_Br4923 IPNALSRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVAIQ
: .*: * :* : :*.*.: ::*** :. :.:: ...:.:*
Mb3530c|M.bovis_AF2122/97 GYSSLGDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLGAM
MAB_4154c|M.abscessus_ATCC_199 GYSSLGNIGIEALTGFLSAFLNVRIVAPVVAGIAMAATIGAGTTAQLGAM
TH_0168|M.thermoresistible__bu GYNQFADIGVEALTGFASAYFNVRLIAPITAGIALAATIGAGATAQLGAM
Mvan_0921|M.vanbaalenii_PYR-1 GYNTLAGVGVEALTGFASAYLNVRIIGPLTTGIGLAATIGAGATAQLGAM
Mflv_2100|M.gilvum_PYR-GCK GYTDFSEIGVEALTGFASAFFNVRLIAPATTAVALAATIGAGATAQLGAM
MUL_3917|M.ulcerans_Agy99 GYSDFSELGVEALTGFASAFFNVRLIAPATTAIALSATIGAGATAQLGAM
MSMEG_0345|M.smegmatis_MC2_155 GYNQFASVGVEALTGFASAFFNVRLIAPGTTAVALSATIGAGATAQLGAM
Rv1965|M.tuberculosis_H37Rv GYNQFASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGTTAALGAM
MMAR_2881|M.marinum_M GYNQFASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGATAQLGAM
MAV_2531|M.avium_104 LYRSLSDVGVEALSGFASAYLNTRFAAPLTSAIGLAATIGAGATAQLGAM
MLBr_02588|M.leprae_Br4923 GFASLGAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELGAM
: :. :*:**::** :* :*.* * : ::**:***:** ****
Mb3530c|M.bovis_AF2122/97 RVSEEIDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAARFT
MAB_4154c|M.abscessus_ATCC_199 RVAEEIDALETMAVHAISYLVSTRLVAGLIAIIPLYSLSVLAAFFASRAT
TH_0168|M.thermoresistible__bu RINEEIDALEVMGIRSLTYLASTRLIAGVIVVIPLYCVAILMSFLAARFG
Mvan_0921|M.vanbaalenii_PYR-1 RIAEEIDALEVMGVRSIAYLASTRLLAGMIVVIPLYCVAVLMSFVAARVG
Mflv_2100|M.gilvum_PYR-GCK RINEEIDALEVMGIRSVAYLASTRVLAGLLVVIPLYCVGVLASFWAARFG
MUL_3917|M.ulcerans_Agy99 RINDEIDALEVMGIRTIAFLAASRVVAGLLVVIPLYCVGVLASFWAARFG
MSMEG_0345|M.smegmatis_MC2_155 RINEEIDALEVIGIRSVSYLASTRVAAGVIVVIPLYCVAVIMSFISSRLG
Rv1965|M.tuberculosis_H37Rv RINEEIDALEVIGIRSISYLASTRVLAGVVVAVPLFCVGLMTAYLAARVG
MMAR_2881|M.marinum_M RINEEIDALEVIGIRSVSYLASTRVLAGVVVAIPLFCVGLITAYLAARAG
MAV_2531|M.avium_104 RINEEIDALEVMGIRAISYLASTRIVAGVLVTVPLWCLSSLAGYLATRTL
MLBr_02588|M.leprae_Br4923 RISEEIDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPHII
*: :****:* :.::::::*.::*: **::. :**:.:. : .: :.:
Mb3530c|M.bovis_AF2122/97 TVFVNGQSAGLYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGYNA
MAB_4154c|M.abscessus_ATCC_199 TVMINGQSPGVYDHYFNTFLVPTDLLWSFLQAIVMSVVVMLVHTSYGFNA
TH_0168|M.thermoresistible__bu TTFVYGQSTGVYDHYFNTFLRPTDVIWSFFQAVVMAIVIMIVHTYYGYNA
Mvan_0921|M.vanbaalenii_PYR-1 TTAIYGQSTGVYDHYFTTFLNPLDLVWSFVQAIAMAVTVMVIHTYYGFNA
Mflv_2100|M.gilvum_PYR-GCK TTVIYGQSTGVYDHYFRTFLNPTDLVWSFAQCIVLAIVIMLVHTYYGFSA
MUL_3917|M.ulcerans_Agy99 TTVLYSQATGVYDHYFRTFLNPTDLVWSFVQCIALSLVIMLVHTYYGYTA
MSMEG_0345|M.smegmatis_MC2_155 TTVIYGQGSGVYDHYFNTFLNTNDLLWSFGQSVAITVVIMLVHTYYGYTA
Rv1965|M.tuberculosis_H37Rv TTAIYGQGSGVYDHYFNTFLRPTDVLWSSVEVVVVALMIMLVCTYYGYAA
MMAR_2881|M.marinum_M TTAIYGQGSGVYDHYFNTFLRPTDVLWSSFEVVVVALMIMLVCTYYGYNA
MAV_2531|M.avium_104 VVVAFGQAPGVYDHYFNTYLQPTDLIWSLLQVMATATVVMLVHTYYGFNA
MLBr_02588|M.leprae_Br4923 TTVLYGQSNGTYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGYTA
.. .*. * *:*** *:* . *:.** : : : :*: **: *
Mb3530c|M.bovis_AF2122/97 SGGSVGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
MAB_4154c|M.abscessus_ATCC_199 SGGPVGVGVAVGQAVRTSLIVVVLVTLFISLAVYGGSGNFNLSG
TH_0168|M.thermoresistible__bu SGGPAGVGESVGRAVRTSLIATVFVTVFVSLAIYGQSGNFNLSG
Mvan_0921|M.vanbaalenii_PYR-1 SGGPAGVGEAVGRAVRASLIVVVFVTLVISLSVYGQSGNFNLSG
Mflv_2100|M.gilvum_PYR-GCK RGGPAGVGEAVGRAVRTSLILSAFVLVMISLAVYGQSGNFNLAG
MUL_3917|M.ulcerans_Agy99 RGGPAGVGEAVGRAVRTSLIFSAFVLVMISLAVYGQSGNFNLAG
MSMEG_0345|M.smegmatis_MC2_155 SGGPAGVGEAVGRAVRTSLIVAAIVVVMISLALYGQSGNFHLAG
Rv1965|M.tuberculosis_H37Rv HGGPAGVGEAVGRAVRASMVVASIAILVMTLAIYGQSPNFHLAT
MMAR_2881|M.marinum_M HGGPAGVGEAVGRAVRASMVVASIAIVIMTLAIYGQSPNFHLAS
MAV_2531|M.avium_104 TGGPAGVGEAVGRSVRASLVVAVTVQLAVAMAAYGVSGNFNLSG
MLBr_02588|M.leprae_Br4923 NGGPVGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
**..*** :**:::* *:: : ::: ** . ** *: