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SDPENLAWLPFTIAEATTADKPDTPDLAEAWSHLLARLGEAAQMVESDPANQNRIDAAAGLRHLLVLLAA GIDEALRFDPDPVLRVQRTSTDDVVTWGMECPDCLYTRAVLRGGESYRLFGNRGTARYVGLQTMNGIAAT ANCLVDELETDAEGNFEVVLSASEQTRPGGNWMRIDGEHPTLTVRHFFYDWDVEVPSSLHIEQLGDVTRP ARYGVDPELAVTRQLVALGDFVKNNLTFFLQFGAAAPKNGFLPAIDRTDMGAAAENRPVIGRWELCPNEA LIVEVEPPQGIYWSFSIGNPWWETIHYGRHQSSLNAHQTAVDADGMVRVVLCAEDPGVANWLDTAGHGNG PIILRCVRTTTAPTPRTRVVAFDDISSELPSDTARVTAGQRESIVAARRRAVHERFGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2441 | - | - | 100% (409) | hypothetical protein MAV_2441 |
| M. avium 104 | MAV_0063 | - | 1e-36 | 29.90% (408) | hypothetical protein MAV_0063 |
| M. avium 104 | MAV_5268 | - | 5e-30 | 28.37% (356) | hypothetical protein MAV_5268 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3561c | - | 7e-30 | 29.43% (384) | hypothetical protein Mb3561c |
| M. gilvum PYR-GCK | Mflv_2496 | - | 2e-35 | 30.51% (413) | hypothetical protein Mflv_2496 |
| M. tuberculosis H37Rv | Rv3531c | - | 7e-30 | 29.43% (384) | hypothetical protein Rv3531c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3969 | - | 2e-31 | 29.87% (385) | hypothetical protein MAB_3969 |
| M. marinum M | MMAR_0906 | - | 1e-32 | 28.60% (437) | hypothetical protein MMAR_0906 |
| M. smegmatis MC2 155 | MSMEG_5932 | - | 2e-27 | 26.29% (388) | hypothetical protein MSMEG_5932 |
| M. thermoresistible (build 8) | TH_3890 | - | 2e-36 | 32.08% (318) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0659 | - | 5e-33 | 28.83% (437) | hypothetical protein MUL_0659 |
| M. vanbaalenii PYR-1 | Mvan_4829 | - | 9e-33 | 29.20% (387) | hypothetical protein Mvan_4829 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0906|M.marinum_M ------------------MSAETSQASLHAAWTDMIDALTRARDAVDSAE
MUL_0659|M.ulcerans_Agy99 ------------------MSAETSQASLHAAWTDMIDALTRARDAVDSAE
Mb3561c|M.bovis_AF2122/97 -----------------------------MYSDPLREAIAEAEQLVAAAP
Rv3531c|M.tuberculosis_H37Rv -----------------------------MYSDPLREAIAEAEQLVAAAP
MSMEG_5932|M.smegmatis_MC2_155 -----------------------------MYSQPLVDAIAEAERLVAAAP
Mvan_4829|M.vanbaalenii_PYR-1 -------MRYFIRNIDHSGPILEHMSEVKMYVQEFLDRIAAAERLVREAP
MAB_3969|M.abscessus_ATCC_1997 ------------------------MATDDAVTQPFTDAIAEAEKLVASAP
MAV_2441|M.avium_104 MSDPENLAWLPFTIAEATTADKPDTPDLAEAWSHLLARLGEAAQMVESDP
Mflv_2496|M.gilvum_PYR-GCK ----------------MAYGDGPDDVALRRAWETFCYQVKAAGQQIFKEH
TH_3890|M.thermoresistible__bu ------------------------------MTGTATAVLAPPGNIGAATP
: .
MMAR_0906|M.marinum_M LHAPPVTAAGLADGYGYLLGFVFSGIERAFGENPD--FPYFRRAIQPLDK
MUL_0659|M.ulcerans_Agy99 LHAPPVTAAGLADGYGYLLGFVFSGIERALGENPD--FPYFRRAIQPLDK
Mb3561c|M.bovis_AF2122/97 HIET---EADLLEGLQYLAGCIAGCMHLAFDYERD--HPFLQSGTGPFTK
Rv3531c|M.tuberculosis_H37Rv HIET---EADLLEGLQYLAGCIAGCMHLAFDYERD--HPFLQSGTGPFTK
MSMEG_5932|M.smegmatis_MC2_155 FIES---EADLTEGLQYLAGCVSGCLHLAFDYDRD--HPFLQSGTGPFTK
Mvan_4829|M.vanbaalenii_PYR-1 HVES---EADLLEGLQYLAGCIAACTRLAFDYDRD--HPFLHSGTGPFTK
MAB_3969|M.abscessus_ATCC_1997 HIES---EADLLEGLEYLAGSIAASLHLVYNFSTE--HPVLLSGTGPFTK
MAV_2441|M.avium_104 ANQN---RIDAAAGLRHLLVLLAAGIDEALRFDPDPVLRVQRTSTDDVVT
Mflv_2496|M.gilvum_PYR-GCK NPAS---ELHRVDALRFLTQNLGQAFDLALETRDTR-YPGMHAFCGPTRK
TH_3890|M.thermoresistible__bu EGDN-------------IAEMMALAQAQLLQQAADLVRPVWVPFLSKTIR
: :
MMAR_0906|M.marinum_M ATIDNADALYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHT---DYA--
MUL_0659|M.ulcerans_Agy99 ATIDNADALYLSAPIDGAQSYRVTGRFVGPKPPQYLIFEAHI---DYA--
Mb3561c|M.bovis_AF2122/97 MGLDNPDTLYFGTRLQANRDYVVSGRRGTTTDLSFQLLGGEY---TDY--
Rv3531c|M.tuberculosis_H37Rv MGLDNPDTLYFGTRLQANRDYVVSGRRGTTTDLSFQLLGGEY---TDY--
MSMEG_5932|M.smegmatis_MC2_155 MGLDNPDTLYFGTRVQPGHEYVVTGKRGTTTDLSFQVLGGEY---TDD--
Mvan_4829|M.vanbaalenii_PYR-1 MALDNPDTLYFGTWLQGGHEYVLTGRRGTTTDLSFQLLGGEY---TED--
MAB_3969|M.abscessus_ATCC_1997 MGLDNPDFLYFATQIDGHHDYVLSGTRGSTVDLNFQLLDSAY---TDR--
MAV_2441|M.avium_104 WGMECPDCLYTRAVLRGGESYRLFGNRGTARYVGLQTMNGIA---ATA--
Mflv_2496|M.gilvum_PYR-GCK LGGDCADFTYQQAWIDGDSVYRIHGERGTARFFNITVQGPRP---DGP--
TH_3890|M.thermoresistible__bu SAGANADTTYGVALLEPGGSYRISGRRGTVVFADLLVGAGLLGVVERQQP
.* * : : * : *
MMAR_0906|M.marinum_M GDTGGLAELMPGGRVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFI
MUL_0659|M.ulcerans_Agy99 GDTGGLAELMPGGRVVTGALDTADLAVGEDGRFEILLGPRRPGEHTGNFI
Mb3561c|M.bovis_AF2122/97 NVPA-----------SQAAFDDRELDIAADGSFEWRLRPS----------
Rv3531c|M.tuberculosis_H37Rv NVPA-----------SQAAFDDRELDIAADGSFEWRLRPS----------
MSMEG_5932|M.smegmatis_MC2_155 NVPA-----------SQAAFDDRELDIAEDGTFEWRITPT----------
Mvan_4829|M.vanbaalenii_PYR-1 NVPD-----------NQFAFDDRELDLAVDGSFEWRFTPN----------
MAB_3969|M.abscessus_ATCC_1997 DVPE-----------SVTAFDDRNLAIHEDGSYRVSIGAAPVTGCD----
MAV_2441|M.avium_104 NCLV------------------DELETDAEGNFEVVLSASEQTRPGG---
Mflv_2496|M.gilvum_PYR-GCK GVLHEPFG-----DVPEASLAGAELAVDHDGTFEVFLGGAPRASN-----
TH_3890|M.thermoresistible__bu ---------------NVGVVDFTDLDLGDDDTVELILSAERPAGYDG---
:* :. . :
MMAR_0906|M.marinum_M ATRTPDGTATARFLIARILFHDWEHEMSPDLHIVQIGKQGAQPEP--ADP
MUL_0659|M.ulcerans_Agy99 ATRTPDGTATARFLIARILFHDWEHEMSPDLHIVQIGKQGAQPEP--ADP
Mb3561c|M.bovis_AF2122/97 ---------APGQLVIREVYGDWSQQRG-TLAIARLDTVGTAPPP--LTR
Rv3531c|M.tuberculosis_H37Rv ---------APGQLVIREVYGDWSQQRG-TLAIARLDTVGTAPPP--LTR
MSMEG_5932|M.smegmatis_MC2_155 ---------SPSQLVIREVYNDWSAQRG-HLAIARTDTAGTAPPP--LTK
Mvan_4829|M.vanbaalenii_PYR-1 ---------SDAQLVVREVYNDWSAQRG-TIAIARTDSTGTAPRT--LTP
MAB_3969|M.abscessus_ATCC_1997 --THIPIAPRPAQLIVREAYNDWTENRG-TVAISRADTLGIGAAP--LTK
MAV_2441|M.avium_104 --NWMRIDGEHPTLTVRHFFYDWDVEVPSSLHIEQLGDVTRPARYGVDPE
Mflv_2496|M.gilvum_PYR-GCK ---WLPTTAGSRKLFVRQGFDSWD-EIPARIAIERVDMAEPKPLP---TA
TH_3890|M.thermoresistible__bu --HWFRLDPTADHVWLRQYFYDWETERPWSVTIERLDVAPTDPPK-----
: * : .* : : * : . .
MMAR_0906|M.marinum_M AVVAQNMRRLGTIVENQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNE
MUL_0659|M.ulcerans_Agy99 AVVAQNMRRLGTIVENQMRFWNEFYDVVLEAHGDKNGDGFTLMPRNSLNE
Mb3561c|M.bovis_AF2122/97 ELMEKRYATAGSQLVNRVKTWLQFPQWFYLNI-----------PVNTMVA
Rv3531c|M.tuberculosis_H37Rv ELMEKRYATAGSQLVNRVKTWLQFPQWFYLNI-----------PVNTMVA
MSMEG_5932|M.smegmatis_MC2_155 ELIEKRYAVAGKQLVQRVKTWLQFPQWFYNNL-----------PVNTMVA
Mvan_4829|M.vanbaalenii_PYR-1 ELIAIRYAAAGKHLTRRIRTWLSFPQWFYLNV-----------PVNTLTA
MAB_3969|M.abscessus_ATCC_1997 EFVLGRYIGAGHHLINRVKTWLQFPQWFYMNN-----------PPNVFEP
MAV_2441|M.avium_104 LAVTRQLVALGDFVKNNLTFFLQFGAAAPKNG-----------FLPAIDR
Mflv_2496|M.gilvum_PYR-GCK QQMVDAIAWAGDFLTGVMGDWPEFPFTHGGVD------------ADAPNR
TH_3890|M.thermoresistible__bu --PALRDVEINGFVDRYVSMWQSHVAAMADRG-----------YVNRLET
. : : : ..
MMAR_0906|M.marinum_M PALANLAMGGGQSTNVYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNL
MUL_0659|M.ulcerans_Agy99 PALANLAMGGGQSTNVYCGGVYDLRADEALLVEVVVPVPPAYMGFHLSNL
Mb3561c|M.bovis_AF2122/97 PRLT----PGGLATQYSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSM
Rv3531c|M.tuberculosis_H37Rv PRLT----PGGLATQYSSAGHFELRPGQALVITVPV-SDAPYLGFQLGSM
MSMEG_5932|M.smegmatis_MC2_155 PRLT----PGGLATQYSSVGHFDLRPDQAMVITLPV-TDAPYLGFQLGSL
Mvan_4829|M.vanbaalenii_PYR-1 PRIT----PGGLATQYSSVGHFDLGPGRAMVITLPA-SDAPYLGFQLGSM
MAB_3969|M.abscessus_ATCC_1997 PRIT----PGGLSSQFSSVGYFELEPGQALMVTVPK-SDAPYQGFQLGSM
MAV_2441|M.avium_104 TDMG------AAAENRPVIGRWELCPNEALIVEVEP-PQGIYWSFSIGNP
Mflv_2496|M.gilvum_PYR-GCK FPAVVSTDGDTKRGRAAVNMHWVLTPDEALVIEFDA--HDGFWSLTNMGV
TH_3890|M.thermoresistible__bu VGLP---DTTGMVAQSYFQGVYEIAEDEALLLEVRPPRRCRYWSVQLTDD
. : : ..*::: . : .. .
MMAR_0906|M.marinum_M WGESLDYANHACSLNGFQSEPDADARIRYVIADTDPGVPNWLDTAGRLGG
MUL_0659|M.ulcerans_Agy99 WGESLDYANHACSLNGFQSEPDADARMRYVIADTDPGVPNWLDTAGRLGG
Mb3561c|M.bovis_AF2122/97 WYISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRG
Rv3531c|M.tuberculosis_H37Rv WYISLDYINHQTSLNASQAQADPDGKVRIVVAEQNPGVTNWVETLGHRRG
MSMEG_5932|M.smegmatis_MC2_155 WYISLDYINHQTSLNGTQAQEDPDGKIRIVVSDANPGVTNWCETLGHRKG
Mvan_4829|M.vanbaalenii_PYR-1 WYISLDYINHQTSLNGTQAQVDPDGMIRIVVAHESPGIANWVETLGHRRG
MAB_3969|M.abscessus_ATCC_1997 WYVSLDYINHQTSLNSHQSHVDPDGKIRLVISDQNPGVVNWIETVGHRRG
MAV_2441|M.avium_104 WWETIHYGRHQSSLNAHQTAVDADGMVRVVLCAEDPGVANWLDTAGHGNG
Mflv_2496|M.gilvum_PYR-GCK FFNSMDFRYRPVSYTASRTAVDTDGKVRLVLAHTDPGFHNWIDTQGFERG
TH_3890|M.thermoresistible__bu RYISLDWMWRQTSLNGHQARLDPDGVFRAVISHRDPGVHNWLDAAGWTRG
::.: : * .. :: *.*. .* *:. .**. ** :: * *
MMAR_0906|M.marinum_M FLTLRWTYCD-PPSELPKASAVKVPLASVRQHLPADTR-TVSVEERRRQI
MUL_0659|M.ulcerans_Agy99 FLTLRWTYCD-PPSELPKASAVKVPLASVRQHLPADTR-TVSVEERRRQI
Mb3561c|M.bovis_AF2122/97 FLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARI
Rv3531c|M.tuberculosis_H37Rv FLQFRWQRVSRELTEADGPTVELVDFDAIPAALPHYQHNKISEDDWRARI
MSMEG_5932|M.smegmatis_MC2_155 YLQFRWQRLSRALTEADGPTVEVVDIDQVPEKLPYHESNKISEADWRARI
Mvan_4829|M.vanbaalenii_PYR-1 YLQFRWQRTSRKLTAAEGPIAEVVDFDAIPSRLPYFGHNTISNDDFRTRI
MAB_3969|M.abscessus_ATCC_1997 FLKFRWQRTNRPILDEDGPRAEVVDFDRIKVSLPFHADHIVTAQQWRSRI
MAV_2441|M.avium_104 PIILRCVRTT----TAPTPRTRVVAFDDISSELPSDTA-RVTAGQRESIV
Mflv_2496|M.gilvum_PYR-GCK NVTYRHMLDG----APVPLRTEVVKHSELAGVLPADTA-TVTAEERRAQM
TH_3890|M.thermoresistible__bu TILGRWNRAD----ANPVPSVKLVDFADLPGFLPADVP-RITSDERRAQL
: * . * : ** :: : . :
MMAR_0906|M.marinum_M SVRQEHVQRRYRQY
MUL_0659|M.ulcerans_Agy99 SVRQEHVQRRYRQY
Mb3561c|M.bovis_AF2122/97 ALRQRQIATRMLG-
Rv3531c|M.tuberculosis_H37Rv ALRQRQIATRMLG-
MSMEG_5932|M.smegmatis_MC2_155 ALRQQQIQNRMVG-
Mvan_4829|M.vanbaalenii_PYR-1 ALRQNQIANRMVA-
MAB_3969|M.abscessus_ATCC_1997 AARQTAVATRMLG-
MAV_2441|M.avium_104 AARRRAVHERFGR-
Mflv_2496|M.gilvum_PYR-GCK RVRFDAVGRRYTAL
TH_3890|M.thermoresistible__bu RAR-AAAAQRMG--
* *