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MADESDSPAAEEKSDAATQLDTDEGDDQDQGRVARWRELARRRRLSRAATVLAVGAVMVAALAGLSGWLG YRAYQQHDAQARRNLFVATARQGAVNLTTINYTQVDRDVQRILDSATGAFRDEFEQRSKPFAEVVKAAQS KSEGTVTDAGLESQRGDSAQVLVAVAVKSHTAGGDEPPREWRMRIEVRSVGDDAKVSNVVFVP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2070 | - | - | 100% (203) | hypothetical protein MAV_2070 |
| M. avium 104 | MAV_2538 | - | 2e-48 | 53.37% (193) | hypothetical protein MAV_2538 |
| M. avium 104 | MAV_1969 | - | 1e-46 | 60.81% (148) | hypothetical protein MAV_1969 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 7e-33 | 34.93% (209) | hypothetical protein Mb1398c |
| M. gilvum PYR-GCK | Mflv_2107 | - | 6e-50 | 50.99% (202) | hypothetical protein Mflv_2107 |
| M. tuberculosis H37Rv | Rv1972 | - | 1e-36 | 44.92% (187) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02614 | - | 2e-07 | 25.00% (176) | hypothetical protein MLBr_02614 |
| M. abscessus ATCC 19977 | MAB_1004c | - | 4e-12 | 27.69% (195) | hypothetical protein MAB_1004c |
| M. marinum M | MMAR_4057 | - | 2e-49 | 48.02% (202) | Mce associated membrane protein |
| M. smegmatis MC2 155 | MSMEG_5208 | - | 1e-38 | 43.84% (203) | hypothetical protein MSMEG_5208 |
| M. thermoresistible (build 8) | TH_0481 | - | 8e-45 | 51.79% (195) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3924 | - | 2e-48 | 48.51% (202) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_4598 | - | 1e-50 | 51.49% (202) | hypothetical protein Mvan_4598 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2107|M.gilvum_PYR-GCK ------MADD----------AAAPEGE-------LTDAQEREASTAAEP-
Mvan_4598|M.vanbaalenii_PYR-1 ------MADEKRPAEESTTEVDAPAGSPDATPAPVADPAEMESDTAEDSE
TH_0481|M.thermoresistible__bu ----------------------------------MVDGNVAGAEDVAEA-
MMAR_4057|M.marinum_M ------------------MSDSTTLEEQPEPAEVVEPEGESGQAGVPEAQ
MUL_3924|M.ulcerans_Agy99 ------------------MSDSTTLEEQPEPAEVVEPEGESGQAGVPEAQ
Rv1972|M.tuberculosis_H37Rv ------------------MSVAV---------------------------
MAV_2070|M.avium_104 ----------------------------------MADESDSPAAE-----
MSMEG_5208|M.smegmatis_MC2_155 --------------------------------------------------
Mb1398c|M.bovis_AF2122/97 MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREA
MAB_1004c|M.abscessus_ATCC_199 -------------------MVTMTKEDVDSTNDADTDTADDKETVDSAAE
MLBr_02614|M.leprae_Br4923 -----------------------------------MNWPKTPGTLAAMPD
Mflv_2107|M.gilvum_PYR-GCK --TDTDIDTEDTE------DADAPEAVEDDS-VDADVDETDATPATGAMS
Mvan_4598|M.vanbaalenii_PYR-1 VIEEYDLEAEDSE------ADEAEASEADEA-EASEADEAEAAPRS-PMS
TH_0481|M.thermoresistible__bu ---EDVAEAEDVA------EAEDVAGAEDVAGSASPSDDRRSFPAG----
MMAR_4057|M.marinum_M PRDEDQDETADETQDETQEDADADPEAGEDDAQASDGEQESPKPAP---S
MUL_3924|M.ulcerans_Agy99 PRDEDQDETADET----QEDADADPEAGEDDAQASDGEQESPKPAP---S
Rv1972|M.tuberculosis_H37Rv -------------------DSDAEDDAVSEIAEAAGVSPAPAKPSM---S
MAV_2070|M.avium_104 -------EKSDAAT-----QLDTDEGDDQDQGRVARWRELARRRRL---S
MSMEG_5208|M.smegmatis_MC2_155 --------MADDD------SPDAVESTDAEEAEEAAEDGTPDVKEP--LS
Mb1398c|M.bovis_AF2122/97 LAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWRRRLRVR
MAB_1004c|M.abscessus_ATCC_199 TDSEIAEDAAST-------DTDAASSADSDSETASSDEDGDAAKGA---S
MLBr_02614|M.leprae_Br4923 -------------------EEQTELPVHKEFAGIADYSDPGLSDGS---V
:
Mflv_2107|M.gilvum_PYR-GCK HIKLALIAGLVGVLALAG---LAGWLGYQTYESHQAE-EQRNLFVQVGRQ
Mvan_4598|M.vanbaalenii_PYR-1 HVKVALIAGLVGVLALAG---LTAWMGYRTYEANRDE-HRRELFLQVGRQ
TH_0481|M.thermoresistible__bu ---WVLLAGGLGVLALCLT--LVGWLGYRAYDSRVDE-AQRQLFLQVGRQ
MMAR_4057|M.marinum_M KVRLAIVVGLAAVVAMAA---LASWFGFHAYQSHQAD-QQRKLYVQVARQ
MUL_3924|M.ulcerans_Agy99 KVRLAIVVGLAAVVAMAA---LASWFGFHAYQSHQAD-QQRKLYVQVARQ
Rv1972|M.tuberculosis_H37Rv APRRMLLFGLVVVVALAV---LLCCWGFRVQRARHAQ-DQRGHFLQAARQ
MAV_2070|M.avium_104 RAATVLAVGAVMVAALAG---LSGWLGYRAYQQHDAQ-ARRNLFVATARQ
MSMEG_5208|M.smegmatis_MC2_155 RVALGARVGIAVVVVLAV---LTGWLGYRAYQSYGVE-QQREAFLQAGRQ
Mb1398c|M.bovis_AF2122/97 LPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQ-QRAAAFAAGAKQ
MAB_1004c|M.abscessus_ATCC_199 WVRYAALGAVAAIMVGALV--FSGIFGWKVWQQHQID-AAGEQALAVAIP
MLBr_02614|M.leprae_Br4923 FSQYGIASTVLAVLSAAAV--VFGVVIWRAHHDNSAERAYLTHVMQTAFD
: . . :: : .
Mflv_2107|M.gilvum_PYR-GCK GALNLTTINWESAEADVQRILDSATGTFYDDFQQRAEPFVQVVKQAQSKS
Mvan_4598|M.vanbaalenii_PYR-1 GALNLTTIDWQNAEADVQRILDSATGTFYDDFQQRAQPFVEVVKQAQSKS
TH_0481|M.thermoresistible__bu AAINLTTIDHTRAEADVQRIIDGSTGGFREDFESRSAPFIEVVRQAESKS
MMAR_4057|M.marinum_M GAINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIQVVQHFQSKS
MUL_3924|M.ulcerans_Agy99 GAINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIKVVQHFQSKS
Rv1972|M.tuberculosis_H37Rv CALNLTTIDWRNAEADVRRILDGATGEFYNDFAQRSQPFVEVLRHAKAST
MAV_2070|M.avium_104 GAVNLTTINYTQVDRDVQRILDSATGAFRDEFEQRSKPFAEVVKAAQSKS
MSMEG_5208|M.smegmatis_MC2_155 AATALTNVGWETADADVQRVLDSASGTFFDDFQKRAESYLEVVKQVQSKS
Mb1398c|M.bovis_AF2122/97 GVINMNSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVT
MAB_1004c|M.abscessus_ATCC_199 YTETLTSIDSNDIDESFRKILNGATGDLKKDFTPASVQLRQLLLDNKAAS
MLBr_02614|M.leprae_Br4923 WTGVLINMNTSNVDASLQRLHAGTVGELNTDFDAAVQPYRKVVEKLQTQS
. : .:. . .. :: .: * : :* ::: : :
Mflv_2107|M.gilvum_PYR-GCK EGTIAEAGLESATDSE---------------------GQVLVAVTVRTTN
Mvan_4598|M.vanbaalenii_PYR-1 VGTVAEAGLESAGANE---------------------AQVLVAVTVKTSN
TH_0481|M.thermoresistible__bu EGTVTEAGLESMDDDE---------------------GQVLVAVSVRTTT
MMAR_4057|M.marinum_M VGTITAAALESESDDA---------------------AQVLVAVSVKTTT
MUL_3924|M.ulcerans_Agy99 VGTITAAALESESDDA---------------------AQVLVAVSVKTTT
Rv1972|M.tuberculosis_H37Rv VGTITEAGLQTQTADT---------------------AQALVAVSVQTSN
MAV_2070|M.avium_104 EGTVTDAGLESQRGDS---------------------AQVLVAVAVKSHT
MSMEG_5208|M.smegmatis_MC2_155 EGTITSSALESVDDNT---------------------AKVLVSVTVKSTN
Mb1398c|M.bovis_AF2122/97 EGTVNATAVESMNEHS---------------------AVVLVAATSRVTN
MAB_1004c|M.abscessus_ATCC_199 HGKVVNSAIQYKSTNK---------------------VVLLMMVDQSITN
MLBr_02614|M.leprae_Br4923 RGQIEAVAIESVHHDLDTQPGVAHPVVTTKLLPPAARTDSVMLVATSVSE
* : .:: :: .
Mflv_2107|M.gilvum_PYR-GCK AGTPEQQPRAWRMRISVQEIDGDAKVSNVEFVP
Mvan_4598|M.vanbaalenii_PYR-1 AGAPEQEPRAWRMRISVEKIGDDAKVSNVEFVP
TH_0481|M.thermoresistible__bu PADPEPQPRSWRMRITVQKDHDEAKVSNVEFVP
MMAR_4057|M.marinum_M AGAPEQRPRAWRMRITVQQVGDEAKVANVEFVP
MUL_3924|M.ulcerans_Agy99 AAAPEQRPRAWRMRITVQQVGDEAKVANVEFVP
Rv1972|M.tuberculosis_H37Rv AGEADPVPRAWRMRITVQRVGDRVKVSDVGFVP
MAV_2070|M.avium_104 AGGDEP-PREWRMRIEVRSVGDDAKVSNVVFVP
MSMEG_5208|M.smegmatis_MC2_155 AGVPEQAPQFWRMRLTVEENAGQAKVSDVEFIE
Mb1398c|M.bovis_AF2122/97 SAGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
MAB_1004c|M.abscessus_ATCC_199 TQRPDPRVDKSRMKITMEKIDGRWLASKLEYL-
MLBr_02614|M.leprae_Br4923 NVGGKPTTVHWSLRLDVSDVDGKLMISHLESIR
. ::: : . :.: :