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ADEKRPAEESTTEVDAPAGSPDATPAPVADPAEMESDTAEDSEVIEEYDLEAEDSEADEAEASEADEAEA SEADEAEAAPRSPMSHVKVALIAGLVGVLALAGLTAWMGYRTYEANRDEHRRELFLQVGRQGALNLTTID WQNAEADVQRILDSATGTFYDDFQQRAQPFVEVVKQAQSKSVGTVAEAGLESAGANEAQVLVAVTVKTSN AGAPEQEPRAWRMRISVEKIGDDAKVSNVEFVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4598 | - | - | 100% (244) | hypothetical protein Mvan_4598 |
| M. vanbaalenii PYR-1 | Mvan_0519 | - | 4e-56 | 54.10% (183) | hypothetical protein Mvan_0519 |
| M. vanbaalenii PYR-1 | Mvan_0919 | - | 6e-36 | 41.27% (189) | hypothetical protein Mvan_0919 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 1e-33 | 32.28% (254) | hypothetical protein Mb1398c |
| M. gilvum PYR-GCK | Mflv_2107 | - | 8e-77 | 66.37% (223) | hypothetical protein Mflv_2107 |
| M. tuberculosis H37Rv | Rv1972 | - | 1e-49 | 54.69% (192) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02614 | - | 7e-06 | 21.71% (175) | hypothetical protein MLBr_02614 |
| M. abscessus ATCC 19977 | MAB_1004c | - | 3e-14 | 25.00% (228) | hypothetical protein MAB_1004c |
| M. marinum M | MMAR_4057 | - | 3e-63 | 50.22% (231) | Mce associated membrane protein |
| M. avium 104 | MAV_2538 | - | 6e-63 | 61.03% (195) | hypothetical protein MAV_2538 |
| M. smegmatis MC2 155 | MSMEG_5208 | - | 3e-52 | 51.31% (191) | hypothetical protein MSMEG_5208 |
| M. thermoresistible (build 8) | TH_0481 | - | 3e-53 | 52.58% (213) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3924 | - | 1e-61 | 49.35% (231) | Mce associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4598|M.vanbaalenii_PYR-1 ------------MADEKRPAEESTTEVDAPAGSPDATPAPVADPAEMESD
Mflv_2107|M.gilvum_PYR-GCK ------------MADD----------AAAPEGE-------LTDAQEREAS
MMAR_4057|M.marinum_M ------------MSDS-------TTLEEQPEPAEVVEPEGESGQAGVPEA
MUL_3924|M.ulcerans_Agy99 ------------MSDS-------TTLEEQPEPAEVVEPEGESGQAGVPEA
MAV_2538|M.avium_104 -------------------------------------------------M
Rv1972|M.tuberculosis_H37Rv ------------------------------------------------MS
TH_0481|M.thermoresistible__bu ---------------------------------------MVDGNVAGAED
MSMEG_5208|M.smegmatis_MC2_155 --------------------------------------------------
Mb1398c|M.bovis_AF2122/97 MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREA
MAB_1004c|M.abscessus_ATCC_199 ----------------------MVTMTKEDVDSTNDADTDTADDKETVDS
MLBr_02614|M.leprae_Br4923 -----------------------------------------MNWPKTPGT
Mvan_4598|M.vanbaalenii_PYR-1 TAEDSEVIEEYDLEAEDSEADEAEASEADEAEASEADEAEAAPRS-PMSH
Mflv_2107|M.gilvum_PYR-GCK TAAEP---TDTDIDTEDTEDADAPEAVEDDSVDADVDETDATPATGAMSH
MMAR_4057|M.marinum_M QPRDEDQDETADETQDETQEDADADPEAGEDDAQASDGEQESP-KPAPSK
MUL_3924|M.ulcerans_Agy99 QPRDEDQDETADET----QEDADADPEAGEDDAQASDGEQESP-KPAPSK
MAV_2538|M.avium_104 EARDDE------------VEDYDAS----VDDAAEPDAEDPAPAKKLRSP
Rv1972|M.tuberculosis_H37Rv VAVDSD------------AEDDAVS------EIAEAAGVSPAPAKPSMSA
TH_0481|M.thermoresistible__bu VAEAED-----------VAEAEDVAEAEDVAGAEDVAGSASPSDDRRSFP
MSMEG_5208|M.smegmatis_MC2_155 MADDD---------------SPDAVESTDAEEAEEAAEDGTPDVKEPLSR
Mb1398c|M.bovis_AF2122/97 LAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWRRRLRVR
MAB_1004c|M.abscessus_ATCC_199 AAETDS------EIAEDAASTDTDAASSADSDSETASSDEDGDAAKGASW
MLBr_02614|M.leprae_Br4923 LAAMPD---------------EEQTELPVHKEFAGIADYSDPGLSDGSVF
.
Mvan_4598|M.vanbaalenii_PYR-1 VKVALIAGLVGVLALAG-LTAWMGYRTYEANRDEHRRE---LFLQVGRQG
Mflv_2107|M.gilvum_PYR-GCK IKLALIAGLVGVLALAG-LAGWLGYQTYESHQAEEQRN---LFVQVGRQG
MMAR_4057|M.marinum_M VRLAIVVGLAAVVAMAA-LASWFGFHAYQSHQADQQRK---LYVQVARQG
MUL_3924|M.ulcerans_Agy99 VRLAIVVGLAAVVAMAA-LASWFGFHAYQSHQADQQRK---LYVQVARQG
MAV_2538|M.avium_104 ALLATVFGLVTVVGLAA-LGGWFGYQTYQSHQAQQQRE---LMVRIGRQG
Rv1972|M.tuberculosis_H37Rv PRRMLLFGLVVVVALAV-LLCCWGFRVQRARHAQDQRG---HFLQAARQC
TH_0481|M.thermoresistible__bu AGWVLLAGGLGVLALCLTLVGWLGYRAYDSRVDEAQRQ---LFLQVGRQA
MSMEG_5208|M.smegmatis_MC2_155 VALGARVGIAVVVVLAV-LTGWLGYRAYQSYGVEQQRE---AFLQAGRQA
Mb1398c|M.bovis_AF2122/97 LPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAAAFAAGAKQG
MAB_1004c|M.abscessus_ATCC_199 VRYAALGAVAAIMVGALVFSGIFGWKVWQQHQIDAAGE---QALAVAIPY
MLBr_02614|M.leprae_Br4923 SQYGIASTVLAVLSAAAVVFGVVIWRAHHDNSAERAYLT--HVMQTAFDW
: . : . .
Mvan_4598|M.vanbaalenii_PYR-1 ALNLTTIDWQNAEADVQRILDSATGTFYDDFQQRAQPFVEVVKQAQSKSV
Mflv_2107|M.gilvum_PYR-GCK ALNLTTINWESAEADVQRILDSATGTFYDDFQQRAEPFVQVVKQAQSKSE
MMAR_4057|M.marinum_M AINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIQVVQHFQSKSV
MUL_3924|M.ulcerans_Agy99 AINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIKVVQHFQSKSV
MAV_2538|M.avium_104 ALNLTTIDWQHADADVQRILDSATGTFYDDFSHRSKPFIDVVKKAQSKSV
Rv1972|M.tuberculosis_H37Rv ALNLTTIDWRNAEADVRRILDGATGEFYNDFAQRSQPFVEVLRHAKASTV
TH_0481|M.thermoresistible__bu AINLTTIDHTRAEADVQRIIDGSTGGFREDFESRSAPFIEVVRQAESKSE
MSMEG_5208|M.smegmatis_MC2_155 ATALTNVGWETADADVQRVLDSASGTFFDDFQKRAESYLEVVKQVQSKSE
Mb1398c|M.bovis_AF2122/97 VINMNSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVTE
MAB_1004c|M.abscessus_ATCC_199 TETLTSIDSNDIDESFRKILNGATGDLKKDFTPASVQLRQLLLDNKAASH
MLBr_02614|M.leprae_Br4923 TGVLINMNTSNVDASLQRLHAGTVGELNTDFDAAVQPYRKVVEKLQTQSR
. : .:. . .. :: .: * : ** .:: . : :
Mvan_4598|M.vanbaalenii_PYR-1 GTVAEAGLESAG---------------------ANEAQVLVAVTVKTSNA
Mflv_2107|M.gilvum_PYR-GCK GTIAEAGLESAT---------------------DSEGQVLVAVTVRTTNA
MMAR_4057|M.marinum_M GTITAAALESES---------------------DDAAQVLVAVSVKTTTA
MUL_3924|M.ulcerans_Agy99 GTITAAALESES---------------------DDAAQVLVAVSVKTTTA
MAV_2538|M.avium_104 GTITEAGLESQS---------------------GSEAQVLVAVSVKTSNL
Rv1972|M.tuberculosis_H37Rv GTITEAGLQTQT---------------------ADTAQALVAVSVQTSNA
TH_0481|M.thermoresistible__bu GTVTEAGLESMD---------------------DDEGQVLVAVSVRTTTP
MSMEG_5208|M.smegmatis_MC2_155 GTITSSALESVD---------------------DNTAKVLVSVTVKSTNA
Mb1398c|M.bovis_AF2122/97 GTVNATAVESMN---------------------EHSAVVLVAATSRVTNS
MAB_1004c|M.abscessus_ATCC_199 GKVVNSAIQYKS---------------------TNKVVLLMMVDQSITNT
MLBr_02614|M.leprae_Br4923 GQIEAVAIESVHHDLDTQPGVAHPVVTTKLLPPAARTDSVMLVATSVSEN
* : .:: :: . :
Mvan_4598|M.vanbaalenii_PYR-1 GAPEQEPRAWRMRISVEKIGDDAKVSNVEFVP
Mflv_2107|M.gilvum_PYR-GCK GTPEQQPRAWRMRISVQEIDGDAKVSNVEFVP
MMAR_4057|M.marinum_M GAPEQRPRAWRMRITVQQVGDEAKVANVEFVP
MUL_3924|M.ulcerans_Agy99 AAPEQRPRAWRMRITVQQVGDEAKVANVEFVP
MAV_2538|M.avium_104 GAAEQDPRHWRMRVIVQKVGNDMKVSNVAFVP
Rv1972|M.tuberculosis_H37Rv GEADPVPRAWRMRITVQRVGDRVKVSDVGFVP
TH_0481|M.thermoresistible__bu ADPEPQPRSWRMRITVQKDHDEAKVSNVEFVP
MSMEG_5208|M.smegmatis_MC2_155 GVPEQAPQFWRMRLTVEENAGQAKVSDVEFIE
Mb1398c|M.bovis_AF2122/97 AGAKDEPRAWRLKVTVTEEGGQYKMSKVEFVP
MAB_1004c|M.abscessus_ATCC_199 QRPDPRVDKSRMKITMEKIDGRWLASKLEYL-
MLBr_02614|M.leprae_Br4923 VGGKPTTVHWSLRLDVSDVDGKLMISHLESIR
. ::: : . :.: :