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DQSDAPLLNALADYRDKNRYGFAPPGHRQGRGTDDRVLAVLGREPFLDDVLASGGLDDRRTSNGYLQRAE DLMAEAVGAEIAWFSTCGSSLSVRAAMMAVAGGQGSLLVGRDSHKSIVAGLIFSGVQPRWITPRWDAERH FSHPPSPQQVEEAWDKHPDAAGALVVSPSPYGTCADIAGIAEVCHRRGKPLILDEAWGAHLPFHEDLPTW AMDAGADVCVVSVHKMGAGFEQGSVFHVQGDLIDRDRLSACADLLMTTSPNVLIYAAMDGWRRQMVQHGH QLLGAALDLARQVRDEIELIPDVEVLDDELLGVQASHDLDRMQVLIDVCGTGTSGYQAADWLREHARIDV GMSDHRRILATLSMADDKETLGRLTDALRAWRTAAQDFDPAPRIALPSPGEMQLETVELPRDAFFGRVQE VPTKTAAGRIAAEQITPYPPGIPAVVPGERLNDAVLDYLCSGVAAGTNLPDAADPSLQTIRVLA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2031 | - | - | 100% (485) | Orn/Lys/Arg decarboxylase |
M. avium 104 | MAV_3408 | - | 2e-08 | 24.28% (313) | putative Orn/Lys/Arg decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2560c | - | 5e-05 | 29.67% (91) | amino acid decarboxylase |
M. gilvum PYR-GCK | - | - | - | - | - |
M. tuberculosis H37Rv | Rv2531c | - | 5e-05 | 29.67% (91) | amino acid decarboxylase |
M. leprae Br4923 | MLBr_00524 | adi | 1e-08 | 24.13% (315) | putative amino acid decarboxylase |
M. abscessus ATCC 19977 | MAB_2524 | - | 0.0 | 72.69% (487) | putative Orn/Lys/Arg decarboxylase |
M. marinum M | MMAR_2184 | - | 4e-05 | 28.57% (91) | amino acid decarboxylase |
M. smegmatis MC2 155 | MSMEG_0266 | - | 0.0 | 77.73% (485) | arginine decarboxylase |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_2916 | - | 4e-62 | 33.33% (492) | Orn/Lys/Arg decarboxylase, major region |
CLUSTAL 2.0.9 multiple sequence alignment Mb2560c|M.bovis_AF2122/97 MNPNSVRPRRLHVSALAAVANPSYTRLDTWNLLDDACRHLAEVDLAGLDT Rv2531c|M.tuberculosis_H37Rv MNPNSVRPRRLHVSALAAVANPSYTRLDTWNLLDDACRHLAEVDLAGLDT MMAR_2184|M.marinum_M MKRYSTRPRRLRVSALAAVANPSYARVDTWNLLDDACCHLAEVDLAGMDI MLBr_00524|M.leprae_Br4923 MNRDSGHPRRLRVSALAAVANPSYTRIDTWNVLDDACRHLAEVDRAGLDT MAV_2031|M.avium_104 -------------------------------------------------- MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2524|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_2916|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2560c|M.bovis_AF2122/97 THDVARAKRLMDRIGAYERYWLYPGAQNLATFRAHLDSHSTVRLTEEVSL Rv2531c|M.tuberculosis_H37Rv THDVARAKRLMDRIGAYERYWLYPGAQNLATFRAHLDSHSTVRLTEEVSL MMAR_2184|M.marinum_M THDMAKVRRLMDRIGAYERYWLYPGAQNLANFRAHLESKSTVRLKEEVSL MLBr_00524|M.leprae_Br4923 AHDVARVKRLLDRIGAYERYWLYPGAANLAAFRGYLATMATVQLTEEVSL MAV_2031|M.avium_104 -------------------------------------------------- MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2524|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_2916|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2560c|M.bovis_AF2122/97 AVRLLSEYGDRTALFDTSASLAEQELVAQAKQQQFYTVLLADDSPATAPD Rv2531c|M.tuberculosis_H37Rv AVRLLSEYGDRTALFDTSASLAEQELVAQAKQQQFYTVLLADDSPATAPD MMAR_2184|M.marinum_M AVRLLGEYGDRTALFDTSAPLAEQELVAQAKQQQFYTVLVADDAPTSAPD MLBr_00524|M.leprae_Br4923 AVRLLSEYGDRTALFDTSAPLADQELVAQAKQQQFYTVLLADDAPSTAPD MAV_2031|M.avium_104 -------------------------------------------------- MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2524|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_2916|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2560c|M.bovis_AF2122/97 SLAECLRQLRNPADEVQFELLVVASIEDAITAVALNGEIQAAIIRHDLPL Rv2531c|M.tuberculosis_H37Rv SLAECLRQLRNPADEVQFELLVVASIEDAITAVALNGEIQAAIIRHDLPL MMAR_2184|M.marinum_M SLAEHLRALHNPSDDVQFEVLLAPSVEDAITAVALNGEIQAAIIRHDLPL MLBr_00524|M.leprae_Br4923 CLAESLRELRNPSDDVQFELLVVSSVEDAITAVALNGEIQAAIIRHDLPL MAV_2031|M.avium_104 -------------------------------------------------- MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2524|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_2916|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2560c|M.bovis_AF2122/97 RSRDRVPLMTTLLGTDGDE---AVANETHDWVECAEWIRELRPHIDLYLL Rv2531c|M.tuberculosis_H37Rv RSRDRVPLMTTLLGTDGDE---AVANETHDWVECAEWIRELRPHIDLYLL MMAR_2184|M.marinum_M RSRDRLPLMNALLGANDDV---VAPDSPHDWIECGEWIRELRPHIDLYLL MLBr_00524|M.leprae_Br4923 RSRDRVPLMNTLLGANDSEGALVTIDRPHDWVECGEWIRELRPHIDLYLL MAV_2031|M.avium_104 -------------------------------------------------- MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2524|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_2916|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2560c|M.bovis_AF2122/97 TDESIAAETQDEPDVYDRTFYRLNDVTDLHSTVLAGLRNRYATPFFDALR Rv2531c|M.tuberculosis_H37Rv TDESIAAETQDEPDVYDRTFYRLNDVTDLHSTVLAGLRNRYATPFFDALR MMAR_2184|M.marinum_M TDESIAAGAEDDPDVYDRTFYRLNDVTDLHSTVLAGLRNRFATPFFDALR MLBr_00524|M.leprae_Br4923 TDESIAAGNDDEPDVYDRTFYRLNDVTDLNSTVLAGLRNRFATPFFDALR MAV_2031|M.avium_104 -------------------------------------MDQSDAPLLNALA MSMEG_0266|M.smegmatis_MC2_155 -------------------------------------MDQTETPLLDALN MAB_2524|M.abscessus_ATCC_1997 -------------------------------------MDHTQTPFLDAVD Mvan_2916|M.vanbaalenii_PYR-1 -----------------------------------MGFEHSRAPLFESLR :: :*::::: Mb2560c|M.bovis_AF2122/97 AYAAAPVGQFHALPVARGASIFNSKSLHDMGEFYGRNIFMAETSTTSGGL Rv2531c|M.tuberculosis_H37Rv AYAAAPVGQFHALPVARGASIFNSKSLHDMGEFYGRNIFMAETSTTSGGL MMAR_2184|M.marinum_M AYAAAPVGQFHALPVARGASIFNSKSLQDMGEFYGRNIFMAETSTTSGGL MLBr_00524|M.leprae_Br4923 AYAAAPVGQFHALPVARGASIFNSRSLQDMGEFYGRNIFMAETSTTSGGL MAV_2031|M.avium_104 DYRDKNRYGFAPPGHRQGRGTDDR-----VLAVLGREPFLDDVLASG-GL MSMEG_0266|M.smegmatis_MC2_155 EYHASNRYGYSPPGHRQGRGVDDR-----VLRVLGREPFLSDVLANG-GL MAB_2524|M.abscessus_ATCC_1997 RYHRDNRYGFTPPGHRQGRGVDAR-----VTGIMGMDPFRCDLLASG-GL Mvan_2916|M.vanbaalenii_PYR-1 TFVERDQAPFYSPGHKGGRTIDP---------WLRENIAAVDLNNLP-DT : : . * : : . Mb2560c|M.bovis_AF2122/97 DSLLDPHGNIKTAMDKAAVTWNANQTYFVTNGTSTANKIVVQALTRP-GD Rv2531c|M.tuberculosis_H37Rv DSLLDPHGNIKTAMDKAAVTWNANQTYFVTNGTSTANKIVVQALTRP-GD MMAR_2184|M.marinum_M DSLLDPHGNIKKAMDKAASTWNADHTYFVTNGTSTANKIVVQSLTRP-GD MLBr_00524|M.leprae_Br4923 DSLLDPHGNIKKAMDKAAVTWRANHTYFVTNGTSTANKIVVQSLTRP-GD MAV_2031|M.avium_104 DDRRTSNGYLQRAEDLMAEAVGAEIAWFSTCGSSLSVRAAMMAVAGG-QG MSMEG_0266|M.smegmatis_MC2_155 DDRRSSNGYLQKAEDLMAEAVGADTAWFSTCGSSLSVKAAMMAVAGG-DG MAB_2524|M.abscessus_ATCC_1997 DDRKSSGHYLAQAEELMADAVGASSAFFSTCGSSLSVKAAMMAVAGGCEG Mvan_2916|M.vanbaalenii_PYR-1 DTLHCPEGPILEAERLIADAWGVPQSFLMVQGSTGGNIAVALTALRP-DE * . : * * : . ::: . *:: . . : Mb2560c|M.bovis_AF2122/97 IVLIDRNCHKSHHYGLVLAGAYPMYLDAYPLPQYAIYGAVPLRTIKQALL Rv2531c|M.tuberculosis_H37Rv IVLIDRNCHKSHHYGLVLAGAYPMYLDAYPLPQYAIYGAVPLRTIKQALL MMAR_2184|M.marinum_M IVLIDRNCHKSHHYGLVLAGAYPLYLDAYPLPPFAIYGAVSLHTIKQVLL MLBr_00524|M.leprae_Br4923 IVLIDRNCHKSHHYGLVLAGAYPMYLDAYPLPQFAIYGAVSLRTIKKALL MAV_2031|M.avium_104 SLLVGRDSHKSIVAGLIFSGVQPRWITPRWDAERHFSHPPSPQQVEEAWD MSMEG_0266|M.smegmatis_MC2_155 SLLLSRDSHKSVVAGLIFSGVMPRWITPRWDADRHLSHPPSPEEVEETWR MAB_2524|M.abscessus_ATCC_1997 GLLVGRDSHKSIIAGLIFSGVQPRWITPRWDAQRHISHPPSPRQVEEAWQ Mvan_2916|M.vanbaalenii_PYR-1 PVLVARNAHKSVLAGLVQVGARPVWLEPRWDAEFGVAHGLDAAVVARAFE :*: *:.*** **: *. * :: . . . : .. Mb2560c|M.bovis_AF2122/97 DLEAAGQLHRVRMLLLTNCTFDGVVYNPRRVMEEVLAIKPDICFLWDEAW Rv2531c|M.tuberculosis_H37Rv DLEAAGQLHRVRMLLLTNCTFDGVVYNPRRVMEEVLAIKPDICFLWDEAW MMAR_2184|M.marinum_M DLEAAGQLHKVRMLLLTNCTFDGVVYNPRLVMEEVLAIKPDICFLWDEAW MLBr_00524|M.leprae_Br4923 DLEAVRQLDRVRMLLLTNCTFDGVVCNPQRVMEEVLAIKPDICFLWDEAW MAV_2031|M.avium_104 KHPDAAGALVVSPSPYGTCADIAGIAE--------VCHRRGKPLILDEAW MSMEG_0266|M.smegmatis_MC2_155 RYPDAAGALIVSPSPYGTCADLAGIAD--------VCHARGKPLIVDEAW MAB_2524|M.abscessus_ATCC_1997 QHPDAAGALIVSPSPYGTCADIGAIAQ--------VCHRRGKPLIVDEAW Mvan_2916|M.vanbaalenii_PYR-1 TT-GATALWALHPTYYGTTGDLAALAD--------LCRRYGARLLLDGAH . : . . : : :. . :: * * Mb2560c|M.bovis_AF2122/97 YAFATAVPWARQRTAMIAAERLEQMLSTAEYAEEYRNWCASMDGVDRSEW Rv2531c|M.tuberculosis_H37Rv YAFATAVPWARQRTAMIAAERLEQMLSTAEYAEEYRNWCASMDGVDRSEW MMAR_2184|M.marinum_M YAFATAVPWARQRTAMVSAEYLESMLASDEYGAVYEKWRASMQGIPRSQW MLBr_00524|M.leprae_Br4923 YAFATAVPWARQRTAMVSAEQLEQKLWSVEYAEEYRNWCASMAEIPRSQW MAV_2031|M.avium_104 G----------------------------------------------AHL MSMEG_0266|M.smegmatis_MC2_155 G----------------------------------------------AHL MAB_2524|M.abscessus_ATCC_1997 G----------------------------------------------AHL Mvan_2916|M.vanbaalenii_PYR-1 S----------------------------------------------PHF .. Mb2560c|M.bovis_AF2122/97 VDHRLLPDPNRARVRVYATHSTHKSLSALRQASMIHVRDQDFKALTRDAF Rv2531c|M.tuberculosis_H37Rv VDHRLLPDPNRARVRVYATHSTHKSLSALRQASMIHVRDQDFKALTRDAF MMAR_2184|M.marinum_M AEHRLLPDPKRARVRVYATHSTHKSLSALRQASMIHVRDQDFNALTRDAF MLBr_00524|M.leprae_Br4923 VDQRLLPDPNRARIRVYATHSTHKSLSALRQASMIHVRDQDFNALARDAF MAV_2031|M.avium_104 PFHEDLPTWAMDAGADVCVVSVHKMGAGFEQGSVFHVQG---DLIDRDRL MSMEG_0266|M.smegmatis_MC2_155 PFHENLPTWAMNAGADVCVVSVHKMGAGFEQGSAFHLQG---DLIDQDRL MAB_2524|M.abscessus_ATCC_1997 PFHEELPTWAMDAGADVCVVSVHKMGAGFEQGSVFHLQG---DRVDPARL Mvan_2916|M.vanbaalenii_PYR-1 AFHPDLPTPGEQSGAAATVHSVHKILSGLSQAAVLHVDT---AQLDEASV : ** . *.** :.: *.: :*: : . Mb2560c|M.bovis_AF2122/97 GEAFLTHTSTSPNQQLLASLDLARRQVDIEGFELVRHVYNMALVFRHRVR Rv2531c|M.tuberculosis_H37Rv GEAFLTHTSTSPNQQLLASLDLARRQVDIEGFELVRHVYNMALVFRHRVR MMAR_2184|M.marinum_M GEAFLTHTSTSPNQQLLASLDLARRQVDIEGFQLVRQVYDMALVFRHRVR MLBr_00524|M.leprae_Br4923 GEAFLTHTSTSPNQQLLASLDLARRQVDIEGFQLVRLVYDMALVFRHRVR MAV_2031|M.avium_104 SACADLLMTTSPNVLIYAAMDGWRRQMVQHGHQLLGAALDLARQVRDEIE MSMEG_0266|M.smegmatis_MC2_155 SACADLLMTTSPNVLVYSAIDGWRRQMVEHGHRLFGAALDLADDTRRRIE MAB_2524|M.abscessus_ATCC_1997 SACADLLMTTSPNVMVYAAMDGWRRQMVEHGHELLSHALDLAEQVRGEIA Mvan_2916|M.vanbaalenii_PYR-1 RRSLQLIQTTSPHFAIMASVDLARRQMVLDGHALLDATLTRAREAADRLS . :***: : :::* ***: .*. *. . * .: Mb2560c|M.bovis_AF2122/97 KDRLISKWFRILDESDLVPDAFRSSTVSSYRQVRQGALADWNEAWRSDQF Rv2531c|M.tuberculosis_H37Rv KDRLISKWFRILDESDLVPDAFRSSTVSSYRQVRQGALADWNEAWRSDQF MMAR_2184|M.marinum_M KDRLISKWFRILDEADLVPEEFRASSVSSYRQVRQGALAEWNEAWRSDQF MLBr_00524|M.leprae_Br4923 KDRLISKWFRILDESDLVPDEYRASAVSSYRQVRQGALAEWNEAWRSDQF MAV_2031|M.avium_104 L----------IPDVEVLDDELLGVQAS---------------------H MSMEG_0266|M.smegmatis_MC2_155 E----------IDDVEVLDEELLGAQAS---------------------H MAB_2524|M.abscessus_ATCC_1997 D----------IADVQVMESELLGAEAS---------------------H Mvan_2916|M.vanbaalenii_PYR-1 Q----------VPGLTVLRPEHLAGAGTGL-------------------C : :: . : Mb2560c|M.bovis_AF2122/97 VLDPTRLTLFIGATGMNGYDFREKILMERFGIQINKTSINSVLLIFTIGV Rv2531c|M.tuberculosis_H37Rv VLDPTRLTLFIGATGMNGYDFREKILMERFGIQINKTSINSVLLIFTIGV MMAR_2184|M.marinum_M VLDATRVTLFIGSTGMNGYDFREKILMERFGIQINKTSINSVLLIFTIGV MLBr_00524|M.leprae_Br4923 VLDPTRVTLFVGKTGMNGYDFREKILMERFGIQINKTSINSVLLIFTIGV MAV_2031|M.avium_104 DLDRMQVLIDVCGTGTSGYQAAD-WLREHARIDVGMSDHRRILATLSMAD MSMEG_0266|M.smegmatis_MC2_155 DLDRLQILIDVSATGTSGYQAAD-WLRENCQVDVGMSDHRRILATMSVAD MAB_2524|M.abscessus_ATCC_1997 DLDRLQVLVDISQTGTSGYQAAD-WLRQHKQLDLGLSDHRRFLATMSIAD Mvan_2916|M.vanbaalenii_PYR-1 QLDETKLLVGTAGVDADARDILG-RLNRIHGVQPELAGAGHILCISTIGN ** :: : .. .. : * . :: :. .* ::. Mb2560c|M.bovis_AF2122/97 TWSSVHYLLDVLRRVAIDLDRSQKAASGADLALHRRHVEEITQDLPHLPD Rv2531c|M.tuberculosis_H37Rv TWSSVHYLLDVLRRVAIDLDRSQKAASGADLALHRRHVEEITQDLPHLPD MMAR_2184|M.marinum_M TWSSVHYLLDVLRRIATDFDRSQRAASAADWALHERRVEEITQDLPHLPD MLBr_00524|M.leprae_Br4923 TWSSVHYLLDVLRRVASDFDRIQKVASGADLALHQRHVEEITQDLPHLPD MAV_2031|M.avium_104 DKETLGRLTDALRAWRTAAQDFDPAPR-IALPSPG----EMQLETVELP- MSMEG_0266|M.smegmatis_MC2_155 GSDTAGRLLHALSLWRKAADDFAPPPP-IDLPSPA----ELQLTTKTSP- MAB_2524|M.abscessus_ATCC_1997 RDLTVERLLGSLSAWRAAAEDFPRPRP-LYLPPPQ----QLQLESVMLP- Mvan_2916|M.vanbaalenii_PYR-1 IDDDFYRLTTAFEEVSAHFGRRDAEGAGAWTADVL----AVRPELVLTP- * : . : * Mb2560c|M.bovis_AF2122/97 FSEFDLAFRPDDASSFGDMRSAFYAGYEEADREYVQIGLAGRRLAEGKTL Rv2531c|M.tuberculosis_H37Rv FSEFDLAFRPDDASSFGDMRSAFYAGYEEADREYVQIGLAGRRLAEGKTL MMAR_2184|M.marinum_M FSEFDIAFRPDDASSFGDMRSAFYAGYDESDREYVQIGMAGRRLAEGRTL MLBr_00524|M.leprae_Br4923 FSEFDVAFRPENASSFGDMRSAFYAGYEESDREYVHIGTAGRQLAEGRTL MAV_2031|M.avium_104 -------------------RDAFFGRVQEVP------------TKTAAGR MSMEG_0266|M.smegmatis_MC2_155 -------------------RDAFFAEVEQIP------------VEHAVGR MAB_2524|M.abscessus_ATCC_1997 -------------------RDAFFGPTDTVA------------IGDAAGH Mvan_2916|M.vanbaalenii_PYR-1 -------------------REAFFAADETVA------------LADAAGR *.**:. : . Mb2560c|M.bovis_AF2122/97 VSTTFVVPYPPGFPVLVPGQLVSKEIIYFLAQLDVKEIHGYNPDLGLSVF Rv2531c|M.tuberculosis_H37Rv VSTTFVVPYPPGFPVLVPGQLVSKEIIYFLAQLDVKEIHGYNPDLGLSVF MMAR_2184|M.marinum_M VSTTFVVPYPPGFPVLVPGQVVSKEIVYFLAQLDVKEIHGYNHELGLSVF MLBr_00524|M.leprae_Br4923 VSTTFVVPYPPGFPVLVPGQVVSKEIIYFLAQLDVKEIHGYNHELGLSVF MAV_2031|M.avium_104 IAAEQITPYPPGIPAVVPGERLNDAVLDYLCSGVAAGTN----------- MSMEG_0266|M.smegmatis_MC2_155 IAAEQITPYPPGIPAVVPGERLNEAVLDYLVTGVQAGMN----------- MAB_2524|M.abscessus_ATCC_1997 IAAEQVTPYPPGIPVVVPGERLTSPVLEYLRSGVKAGMM----------- Mvan_2916|M.vanbaalenii_PYR-1 IAAEAITPYPPGIPVVMPGERLGKDVVDLLLR-LRAAGN----------- ::: :.*****:*.::**: : . :: * Mb2560c|M.bovis_AF2122/97 TQAALARMEAARN-AVATVGAALPAFEVPRDASALNGTVNGDSVLQGVAE Rv2531c|M.tuberculosis_H37Rv TQAALARMEAARN-AVATVGAALPAFEVPRDASALNGTVNGDSVLQGVAE MMAR_2184|M.marinum_M TDVALKRMEAARN-VIASAGAELPAFELAPASSVVN----GDGVLQAVAD MLBr_00524|M.leprae_Br4923 TEKALARMIARRNAASAAVGSAFAAFEIPSDSAAMGGDVNGDRV-EAVAE MAV_2031|M.avium_104 --------------LPDAADPSLQTIRVLA-------------------- MSMEG_0266|M.smegmatis_MC2_155 --------------LPDPADPQMGSIRVMA-------------------- MAB_2524|M.abscessus_ATCC_1997 --------------VPDPADSSLETIRVTAER------------------ Mvan_2916|M.vanbaalenii_PYR-1 --------------PISASDPTMGVVKTVR-------------------- . .. : .. Mb2560c|M.bovis_AF2122/97 DA Rv2531c|M.tuberculosis_H37Rv DA MMAR_2184|M.marinum_M DA MLBr_00524|M.leprae_Br4923 DA MAV_2031|M.avium_104 -- MSMEG_0266|M.smegmatis_MC2_155 -- MAB_2524|M.abscessus_ATCC_1997 -- Mvan_2916|M.vanbaalenii_PYR-1 --