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LINRCHGCGHYFHPPGPACWRCRSTDVAPEPVSGKGTVAAYTINRQPWIPGLDPPYIVAMVELADEPDVR LITNVVDVSADDIRVGLPVEVFFEDWTAMSGDEDSRVWLPLFRPVST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1967 | - | - | 100% (118) | hypothetical protein MAV_1967 |
| M. avium 104 | MAV_2667 | - | 3e-31 | 76.00% (75) | hypothetical protein MAV_2667 |
| M. avium 104 | MAV_0919 | - | 2e-24 | 41.74% (115) | hypothetical protein MAV_0919 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 1e-11 | 31.31% (99) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 1e-24 | 42.74% (117) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 1e-11 | 31.31% (99) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0616 | - | 7e-15 | 36.17% (94) | hypothetical protein MAB_0616 |
| M. marinum M | MMAR_4731 | - | 5e-23 | 41.74% (115) | 3-ketoacyl-CoA thiolase |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 3e-22 | 40.87% (115) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3582 | - | 3e-23 | 42.61% (115) | PUTATIVE protein of unknown function DUF35 |
| M. ulcerans Agy99 | MUL_3408 | - | 2e-17 | 41.49% (94) | hypothetical protein MUL_3408 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 2e-24 | 42.74% (117) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
TH_3582|M.thermoresistible__bu ----VTRPLPQLTFDNEFFWTAGADGQLKILGCRDCDALIHPPQPVCRYC
Mflv_2483|M.gilvum_PYR-GCK ---MSRLPLPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1 ---MSRLPLPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MMAR_4731|M.marinum_M MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MAV_1967|M.avium_104 ---------------------------MLINRCHGCGHYFHPPGPACWRC
MUL_3408|M.ulcerans_Agy99 -----------MSVSAEPIFS------LLIEHCDTCARWVHPATGRCDDC
Mb3572c|M.bovis_AF2122/97 --------------------------MTGVSDIQEAVAQIKAAGPSKPRL
Rv3542c|M.tuberculosis_H37Rv --------------------------MTGVSDIQEAVAQIKAAGPSKPRL
MAB_0616|M.abscessus_ATCC_1997 --------------------------MS-VVDIQEGFAKIKADGPSAPRL
: .:.
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
TH_3582|M.thermoresistible__bu RGHNLAPRVVSGQGILTGFTVNHRFGFPDLPPPYVVAQVAVAEDPRVRLT
Mflv_2483|M.gilvum_PYR-GCK HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1 HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MMAR_4731|M.marinum_M RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MAV_1967|M.avium_104 RSTDVAPEPVSGKGTVAAYTINRQPWIPGLDPPYIVAMVELADEPDVRLI
MUL_3408|M.ulcerans_Agy99 DAA-LVPRPVSGRGTVFTYTVNHHRYHPDIPTPYIIALVELSEQAGLRVA
Mb3572c|M.bovis_AF2122/97 ARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTM
Rv3542c|M.tuberculosis_H37Rv ARDPVNQPMINNWVEAIGDRNPIYVDDAAARAAGHPGIVAPPAMIQVWTM
MAB_0616|M.abscessus_ATCC_1997 ARDPVNQAMINNWVEAMGDRNPIYVDEEAAKAAGHPGIVAPPAMAQVWTM
: :.. .. . * :
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
TH_3582|M.thermoresistible__bu TNIVECDPDELTLGQRVEVLFEKIEDVWLPMFRPTGQTEPADLPADEIAP
Mflv_2483|M.gilvum_PYR-GCK TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1 TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MMAR_4731|M.marinum_M TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MAV_1967|M.avium_104 TNVVDVSADDIRVGLPVEVFF-----------------------------
MUL_3408|M.ulcerans_Agy99 ANIVDCEPDSVTCGMPVTIRPE----------------------------
Mb3572c|M.bovis_AF2122/97 MGLGGVRPKDDPLGPIIKLFDD----------------------------
Rv3542c|M.tuberculosis_H37Rv MGLGGVRPKDDPLGPIIKLFDD----------------------------
MAB_0616|M.abscessus_ATCC_1997 AGLYGERSGDDPLGRVMALLDS----------------------------
.: . * : :
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
TH_3582|M.thermoresistible__bu TDFAKHVRPMLTPDKFEDRAAITGIGASRIGRRLMVPPLSLTIEACEAAV
Mflv_2483|M.gilvum_PYR-GCK QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1 QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MMAR_4731|M.marinum_M QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MAV_1967|M.avium_104 ----------------EDWTAMSGDEDSRVWLPLFRP-------------
MUL_3408|M.ulcerans_Agy99 ----------------------RGTG----GAPLFAPAGR----------
Mb3572c|M.bovis_AF2122/97 ----------------AGYIGVVATNCEQTYHRYLLP-------------
Rv3542c|M.tuberculosis_H37Rv ----------------AGYIGVVATNCEQTYHRYLLP-------------
MAB_0616|M.abscessus_ATCC_1997 ----------------AGYESVVATNYEQIYHRYLEL-------------
. :
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYPGLDIAG-MGEGGVSVLEGALGLRPTWINGGMDT
TH_3582|M.thermoresistible__bu ADAGLTFDDIDGLSTYPGIDTAG-MGEGGVTALEGALGLRPTWINGGMDT
Mflv_2483|M.gilvum_PYR-GCK ADAGLTLADIDGLSTYPAMDAMG-MGEGGCTVLEGALGIRPTWINGGMDT
Mvan_4171|M.vanbaalenii_PYR-1 ADAGLTLADIDGLSTYPAMDAMG-MGEGGVTALEGALGIRPTWINGGMDT
MMAR_4731|M.marinum_M ADAGLTFDDIDGLSTYPGGGNLGGFGEGGVTALEAALGIRPVWHNGGIET
MAV_1967|M.avium_104 ------------VST-----------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 -------------------------------------GEQVSISAELGDV
Rv3542c|M.tuberculosis_H37Rv -------------------------------------GEQVSISAELGDV
MAB_0616|M.abscessus_ATCC_1997 -------------------------------------GEQVTTTNEVTEV
MSMEG_4814|M.smegmatis_MC2_155 FGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKMSPPMSART
TH_3582|M.thermoresistible__bu FGPGGSVIAAMMAVATGLARHVLCFRTLWEASFNQLMKEGRLAPPMGART
Mflv_2483|M.gilvum_PYR-GCK FGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGKASPPGGARV
Mvan_4171|M.vanbaalenii_PYR-1 FGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGRVSPPGGTRV
MMAR_4731|M.marinum_M FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATYNELMKRGKIAPP-GGRT
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 VGPKQTALGEGWFINQHIVWQVG------DEDVAEMNWRILKFKP-AGSP
Rv3542c|M.tuberculosis_H37Rv VGPKQTALGEGWFINQHIVWQVG------DEDVAEMNWRILKFKP-AGSP
MAB_0616|M.abscessus_ATCC_1997 FGPKQTALGESWFINIHAEWHVG------DELVNEMNWRIMKFRPGAKKA
MSMEG_4814|M.smegmatis_MC2_155 NSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQRANAALNPT
TH_3582|M.thermoresistible__bu TSWQMPFGATSAAHTLALNAQRHFHRYGTTRETLGWIALNQRANAALNPT
Mflv_2483|M.gilvum_PYR-GCK NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
Mvan_4171|M.vanbaalenii_PYR-1 NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
MMAR_4731|M.marinum_M TSWQYPFGATSAAHTLAINAQRHFHRYGTTKETLGWIALNQRANAELNPT
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 SSVPDDLDPD-AMMRPSSSRDTAFFWDGVKAHELRIQRLADGSLRHPPVP
Rv3542c|M.tuberculosis_H37Rv SSVPDDLDPD-AMMRPSSSRDTAFFWDGVKAHELRIQRLADGSLRHPPVP
MAB_0616|M.abscessus_ATCC_1997 ADVPQDLDPS-KLMRPSWSRDSAYFWEGVAAHELRLQKRPDGSLQHPPVP
MSMEG_4814|M.smegmatis_MC2_155 AIYREPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAVDAARDLPR
TH_3582|M.thermoresistible__bu AVYRDPLTMDDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAARDLRK
Mflv_2483|M.gilvum_PYR-GCK AIYRDPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAAADAPK
Mvan_4171|M.vanbaalenii_PYR-1 AIYRDPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVVSAVDAAVDLPK
MMAR_4731|M.marinum_M AVYRSPMTMDDYLNARPITTPFGLFDCDVPCDAAIAVIVSAVDAARDLAK
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 AVWQDKSVPINYVVS----------------SGRGTVFSFVVHHAPKVPG
Rv3542c|M.tuberculosis_H37Rv AVWQDKSVPINYVVS----------------SGRGTVFSFVVHHAPKVPG
MAB_0616|M.abscessus_ATCC_1997 AVWQDKEAPIEYQVA----------------SGRGTVYSYVVHHAPQVPG
MSMEG_4814|M.smegmatis_MC2_155 PPIRFEAVGTQIIERLDWDQTTLTHEPQVLGQSAHMWSRTSLRPSDVDVA
TH_3582|M.thermoresistible__bu PPVLVEAVGTQIIERTDWDQTTLTHEPQVLGQSAHLWSRTSLRPEDVDVA
Mflv_2483|M.gilvum_PYR-GCK PPVFFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPDDVDVA
Mvan_4171|M.vanbaalenii_PYR-1 PPVYFEAVGTQIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPADVDVA
MMAR_4731|M.marinum_M PPVLVEAVGTQIIERIDWDQSTLTHEPQVLGQAAHVWTRTTLRPADVDVA
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 RTVPFVIALVELEEGVRMLGELRGADP------ARVAIGMPVRATYIDFP
Rv3542c|M.tuberculosis_H37Rv RTVPFVIALVELEEGVRMLGELRGADP------ARVAIGMPVRATYIDFP
MAB_0616|M.abscessus_ATCC_1997 RTLPFVIALVELDEGVRMLGELRGVSP------DDVQIGLPVRATYLDFP
MSMEG_4814|M.smegmatis_MC2_155 ELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIPLNTHGGQL
TH_3582|M.thermoresistible__bu QLYDGFTFNCLSWIEALGFCGIGEAKDFLDGGRNIARDGVLPLNTHGGQL
Mflv_2483|M.gilvum_PYR-GCK ELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIPLNTHGGQL
Mvan_4171|M.vanbaalenii_PYR-1 ELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDGVIPLNTHGGQL
MMAR_4731|M.marinum_M ELYDGFTMNCLSWIEALGFCGIGEAKEFLDGGKNIARDGLIPLNTHGGQL
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 D------WSLYAWEPDE---------------------------------
Rv3542c|M.tuberculosis_H37Rv D------WSLYAWEPDE---------------------------------
MAB_0616|M.abscessus_ATCC_1997 AEGEDPAWTLYAWEAA----------------------------------
MSMEG_4814|M.smegmatis_MC2_155 SHGRTHGMGLIHEAVTQLRGEAGERQVEDARVAVASSGGLTPSGVLLLRR
TH_3582|M.thermoresistible__bu SHGRTHGMGLIHEAVSQLRGEAGERQVPDARVAVASSGGLXXXRWIPA--
Mflv_2483|M.gilvum_PYR-GCK SHGRTHGMGLVHEAVSQLRGEAGERQVADARVAVVSSGGLTPSGVMLLRT
Mvan_4171|M.vanbaalenii_PYR-1 SHGRTHGMGLIHEAVSQLRGEAGERQVDGARVAVVSSGGLTPSGALLLRT
MMAR_4731|M.marinum_M SHGRTHGMGLLHEAVTQLRGEADARQVAGARVGVVSSGGLTPSGVILLRA
MAV_1967|M.avium_104 --------------------------------------------------
MUL_3408|M.ulcerans_Agy99 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0616|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 DD
TH_3582|M.thermoresistible__bu --
Mflv_2483|M.gilvum_PYR-GCK GA
Mvan_4171|M.vanbaalenii_PYR-1 AT
MMAR_4731|M.marinum_M DT
MAV_1967|M.avium_104 --
MUL_3408|M.ulcerans_Agy99 --
Mb3572c|M.bovis_AF2122/97 --
Rv3542c|M.tuberculosis_H37Rv --
MAB_0616|M.abscessus_ATCC_1997 --