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AYSSTRGDVGDRVGEVLRAWLPHRLTTADATAFNISEFTAPPAGYSGKTAFFTASWTDGSGTVHADDLVL RTQADDHQLFTTPDAPRQAEVMQRLGAQGIPVPDVIGIERDASILGSPFYVMRRVRGRTPPDVPSWHKRG WTVDLSSDERQLLCHNGLRALVDVHRVDDSDTLRFLRGDGDVSRTALQRYLDKLAGWYDWCRDNLVVGAD TLAQAIEVIQLSAPDNSAETVVWGDARVGNMCFGDDLSVVALFDWETAGTGPPDIDLGWWLMFERFLCEA LGFTRLPGVPDDDEFVRRYLQFGGTLTGDIVYYQLVAAFVLSLINNRLARLLVRDGLDAPTAMSYPQTSV ALVERYLDQI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1929 | - | - | 100% (361) | putative phosphotransferase |
| M. avium 104 | MAV_5060 | - | 4e-43 | 31.71% (328) | putative phosphotransferase |
| M. avium 104 | MAV_4058 | - | 6e-29 | 29.18% (305) | phosphotransferase enzyme family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3193 | - | 1e-29 | 28.10% (331) | hypothetical protein Mb3193 |
| M. gilvum PYR-GCK | Mflv_4497 | - | 1e-27 | 30.06% (326) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3168 | - | 2e-31 | 28.40% (331) | hypothetical protein Rv3168 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4482 | - | 4e-29 | 30.67% (326) | putative phosphotransferase |
| M. marinum M | MMAR_1393 | - | 2e-28 | 29.22% (332) | hypothetical protein MMAR_1393 |
| M. smegmatis MC2 155 | MSMEG_2042 | - | 5e-32 | 28.02% (364) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_2648 | - | 8e-35 | 31.66% (338) | PUTATIVE putative phosphotransferase enzyme family protein, |
| M. ulcerans Agy99 | MUL_2483 | - | 3e-27 | 28.61% (332) | hypothetical protein MUL_2483 |
| M. vanbaalenii PYR-1 | Mvan_1869 | - | 2e-25 | 29.07% (289) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3193|M.bovis_AF2122/97 --MA--NEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---E
Rv3168|M.tuberculosis_H37Rv --MA--NEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---E
MMAR_1393|M.marinum_M --MA--NETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---E
MUL_2483|M.ulcerans_Agy99 --MA--NETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---E
MSMEG_2042|M.smegmatis_MC2_155 --MA--NEPA-VEDVSHLQLSSRDVSTVPVALADWLSTVLPAGAEP---R
Mflv_4497|M.gilvum_PYR-GCK --MT--SEPA-VDNVDRLQRSSRDLSDVPAALSRWLSTKLPGVTPDAPVD
Mvan_1869|M.vanbaalenii_PYR-1 --MT--SEPA-VDNVDRLQRSSRDMSNVPAALSQWLSTLIPDITP----E
MAB_4482|M.abscessus_ATCC_1997 --MT--EQTATHEDVARPAESQRDPETLRGALTDWISGQLPADAAL---S
TH_2648|M.thermoresistible__bu MATPGT------------EDIRPTEAELPARLEPVIHRRLPDTAGT----
MAV_1929|M.avium_104 --------------MAYSSTRGDVGDRVGEVLRAWLPHRLTTADAT--AF
: : : :.
Mb3193|M.bovis_AF2122/97 VTVESGVDSTGMSSETIILTARRQ-QDGRSIQQKLVARVAPAAEDVPVFP
Rv3168|M.tuberculosis_H37Rv VTVESGVDSTGMSSETIILTARWQ-QDGRSIQQKLVARVAPAAEDVPVFP
MMAR_1393|M.marinum_M VTVESGVDSTGMSSETIILTARWH-EDHRPVQQKLVARVAPAAGDVPVFP
MUL_2483|M.ulcerans_Agy99 VTVESGVDSTGMSSETIILTARWH-EDHRPVQQKLVARVAPAAGDVPVFP
MSMEG_2042|M.smegmatis_MC2_155 VTVEDGVDSNGMSSETLLLTAEWT-EDGAPVQQRLVARVAPAPGDVPVFS
Mflv_4497|M.gilvum_PYR-GCK ITVEDGIDANGMSSETILLRGRWS-DGGDPVEHRWVARVAPTDADIPVFE
Mvan_1869|M.vanbaalenii_PYR-1 ITVESGIDANGMSSETILLRGRWL-QAGDPVEQRWVARVAPAEADIPVFE
MAB_4482|M.abscessus_ATCC_1997 VDHAELPSANGMSSETILADAQWT-ENGQRTAHRLVIRTAPQPDSSPVFP
TH_2648|M.thermoresistible__bu RITNWRAAERGMSTETFLFDLQRDGPDGPVTVRRLVFRRPP---AVSLFP
MAV_1929|M.avium_104 NISEFTAPPAGYSGKTAFFTASWTDGSGTVHADDLVLRTQAD--DHQLFT
* * :* : * * . :*
Mb3193|M.bovis_AF2122/97 TYRLDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVP
Rv3168|M.tuberculosis_H37Rv TYRLDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVP
MMAR_1393|M.marinum_M SYRLDHQFEVIKLVGELSDVPVPRVRWMEPTGEVLGTPFFLMDYVEGVVP
MUL_2483|M.ulcerans_Agy99 SYRLDHRFEVIKLVGELSDVPVPRVRWMVPTGEVLGTPFFLMDYVEGVVP
MSMEG_2042|M.smegmatis_MC2_155 SYRLDHQFELMRQIGELTDVPVPRVRWLESTGSVLGTPFFLMDRVDGIVP
Mflv_4497|M.gilvum_PYR-GCK HYRLDHQHEVMRLVAESTDVAVPAVRWLEDTGDVLGRPFFLMDRVDGVVP
Mvan_1869|M.vanbaalenii_PYR-1 HYRLDHQHEVMRLVAELTDVAVPPVRWLERRGDVLGRPFFLMDRVEGIVP
MAB_4482|M.abscessus_ATCC_1997 SYDMRRQFDVMDTLGRHSSAVVPPVRWYCDDTAVLGGEFFVMDRVDGDVP
TH_2648|M.thermoresistible__bu DYDLLRQVLVMNRLRDT-EVPVPTVCWLDRDGMELGTPYYVMEQIPTIGS
MAV_1929|M.avium_104 TPDAPRQAEVMQRLGAQ-GIPVPDVIGIERDASILGSPFYVMRRVRGRTP
:: :: : ** * ** :::* : .
Mb3193|M.bovis_AF2122/97 PDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQ
Rv3168|M.tuberculosis_H37Rv PDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQ
MMAR_1393|M.marinum_M PDVMPYTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSD
MUL_2483|M.ulcerans_Agy99 PDVMPYTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSD
MSMEG_2042|M.smegmatis_MC2_155 PDVMPYTFGGNWFADAPADRRRLLQDGTVAVLAKLHSIPDALNRFGFLLD
Mflv_4497|M.gilvum_PYR-GCK PDVMPYTFGDNWLYDASPEQQRALQDRTVEVLAALHSIPDAQRTFGFLQE
Mvan_1869|M.vanbaalenii_PYR-1 PDVMPYTFGDNWLFDATAEQQRQLQDRTVEVLAKLHSIPNAQQVFGFLQD
MAB_4482|M.abscessus_ATCC_1997 PDRMPYTFG-SWVTEASEADRRKMQRLTVDQLARIHAAP--VERFAFLND
TH_2648|M.thermoresistible__bu PGDFPSYHCAGMYFDATSQQRTTMWTGCVRAMADVHTLDWRALRLDALLM
MAV_1929|M.avium_104 PD-VPSWHKRGWTVDLSSDERQLLCHNGLRALVDVHRVDD-SDTLRFLRG
*. .* . . : . : : : :. :* : *
Mb3193|M.bovis_AF2122/97 G-RTSDTTLHRHFNWVRSWYDFAVE-GIGRSPLLERTFEWLQSHWPDDAA
Rv3168|M.tuberculosis_H37Rv G-RTSDTTLHRHFNWVRSWYDFAVE-GIGRSPLLERTFEWLQSHWPDDAA
MMAR_1393|M.marinum_M G-PSGDTALRRHFDWVRSWYDFAVP-GIGNSALIERTFQWLQEHWPSEVA
MUL_2483|M.ulcerans_Agy99 G-PSGDTALRRHFDWVRSWYDFAVP-GIGNSALIERTFQWLQEHWPSEVA
MSMEG_2042|M.smegmatis_MC2_155 VDPPGDTPLRRHFAWLKDWYEFAVT-DIGRSPLVEHALAWLEDNFPSDVA
Mflv_4497|M.gilvum_PYR-GCK IDPPGETALHRHFGWLTRWYAFSSA-DLGSSPLVERAISWLEEHFPHDVA
Mvan_1869|M.vanbaalenii_PYR-1 VDPPGPTALHRHFGWLKNWYEFSVP-DIGRSPLVERALAWLEDRFPEDVA
MAB_4482|M.abscessus_ATCC_1997 A-REGETGLDAHVRRTHEFYEWVRG-DGPTIPLIDRGFEWLRENWPEESL
TH_2648|M.thermoresistible__bu P-DRGRHPLEQVVDYYTDALHWASD-GDPR-PELAAAAEWLRRHLYEPEH
MAV_1929|M.avium_104 DGDVSRTALQRYLDKLAGWYDWCRDNLVVGADTLAQAIEVIQLSAPDNSA
. * . : : :.
Mb3193|M.bovis_AF2122/97 AREP----VLLWGDARVGNVLY-RDFQPVAVLDWEMVALGPRELDVAWMI
Rv3168|M.tuberculosis_H37Rv AREP----VLLWGDARVGNVLY-RDFQPVAVLDWEMVALGPRELDVAWMI
MMAR_1393|M.marinum_M AREP----VLLWGDARVGNVLY-RDFRPVAVLDWEMVTLGPRELDVAWMI
MUL_2483|M.ulcerans_Agy99 AREP----VLLWGDARVGNVLY-RDFRPVAVLDWEMVTLGPRELDVAWMI
MSMEG_2042|M.smegmatis_MC2_155 AGEP----VLAWGDSRIGNVLY-EDFEPVAVLDWEMATVGPRELDVSWII
Mflv_4497|M.gilvum_PYR-GCK ASEP----VLVWGDSRIGNVIY-RDFRPVAVLDWEMATIGPREFDLAWIS
Mvan_1869|M.vanbaalenii_PYR-1 AAEP----VLVWGDSRIGNVIY-QDFSPVAVLDWEMATVGPREFDVAWIS
MAB_4482|M.abscessus_ATCC_1997 SGVGRPIDVVSWGDSRPGNVIY-RDFEPVALLDWEMASVGPRELDLGWII
TH_2648|M.thermoresistible__bu LALC-------WGDSRLSNILYGEDFAVNAVVDWEIAYIGDHEADLAWFL
MAV_1929|M.avium_104 ETVV-------WGDARVGNMCFGDDLSVVALFDWETAGTGPPDIDLGWWL
***:* .*: : *: *:.*** . * : *:.*
Mb3193|M.bovis_AF2122/97 FAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSG
Rv3168|M.tuberculosis_H37Rv FAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSG
MMAR_1393|M.marinum_M FAHMVFEELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSG
MUL_2483|M.ulcerans_Agy99 FAHMVFEELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSG
MSMEG_2042|M.smegmatis_MC2_155 FAHMVFQELAGLAGLPGLPDVLREDDVRATYTRLTGAQLGDLRWFYIYSG
Mflv_4497|M.gilvum_PYR-GCK FAHMVFQELTKLAGLPGMPDFLREDDVRDTYRKLTGVEVGDLHWFHVYSA
Mvan_1869|M.vanbaalenii_PYR-1 FAHMVFQELTKLAGLPGMPDFLREDDVRETYRELTGVEIGDLHWFHVYSA
MAB_4482|M.abscessus_ATCC_1997 FLHRFFQDLAEVATLPGLPDFCKREDIAAEYAALTGHHAADLDFYTAYAA
TH_2648|M.thermoresistible__bu FIDWAFSEYEGTPRLPGTP---GRDETIELYQRLSGLPVRNLRYNELLAV
MAV_1929|M.avium_104 MFERFLCEALGFTRLPGVPD---DDEFVRRYLQFGGTLTGDIVYYQLVAA
: . : : . *** * :: * : * :: : :
Mb3193|M.bovis_AF2122/97 VMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH------
Rv3168|M.tuberculosis_H37Rv VMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH------
MMAR_1393|M.marinum_M VMWACVFMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER------
MUL_2483|M.ulcerans_Agy99 VMWACVFMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER------
MSMEG_2042|M.smegmatis_MC2_155 VIWCCVFMRTGARRVRFGEIEKPEDVESLFYHASLLRRLIEEA-------
Mflv_4497|M.gilvum_PYR-GCK VVWCCVFMRTGTRRVHFGEIERPDDIESLFYHASLLKRLIGEAD------
Mvan_1869|M.vanbaalenii_PYR-1 VVWCCVFMRTGARRVHFGEIERPADIETLFYHASLLKRLIGETD------
MAB_4482|M.abscessus_ATCC_1997 LQHAVIMARIQMRAMAFGQAQMPDDPDDLILHRATLEKMLNGTYWAGVKA
TH_2648|M.thermoresistible__bu LALSVPVTRLETKLRSDGLLAEG--FDLLGFCVERARQLLG---------
MAV_1929|M.avium_104 FVLSLINNRLARLLVRDG-LDAPTAMSYPQTSVALVERYLDQI-------
. . * * . .: :