For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
QKPMTGVRVLEVAQFTFVPSAGAVLADWGADVIKVENPVTGDAQRGLVTVAGRSATAPGVSFSPMVEAPN RGKRSVGLSLALKQTRPVFEELVRRSDVFLTNLLPQARAKLRIHLEEIRRINPSIIYVTGSGFGSQGPDR ETGAHDTTAFWARAGNADGVTPSDSEVPTGIPAGAFGDNVGGITIAGAVAAALYGRQTTGQTSVIDVSLL AVGAWANQSNVNLAMLYGCPLPKIDHRTQAPGNPLTGAYRCSDGRFIQLAMLQPTRYWAPVCRLFGLDAA AADERFASLESLAAHTDEATALLAEAIGARTFDECMQLLKLLHGQWAPVQDAWEVANDESLVANGRIANV LDAQGNPQRLVANPVKFDEAATHLTRAPMFAEHTDEVLRELGMADHELIELKIEGAIT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1895 | - | - | 100% (409) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_2541 | - | e-161 | 68.00% (400) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_0945 | - | 5e-95 | 46.60% (412) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 9e-32 | 31.38% (392) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2503 | - | 3e-92 | 45.99% (411) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 9e-32 | 31.38% (392) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 9e-23 | 26.74% (359) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4713 | - | 4e-98 | 48.54% (412) | dehydratase |
| M. smegmatis MC2 155 | MSMEG_4798 | - | 5e-92 | 45.28% (413) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_4667 | - | 1e-95 | 47.50% (400) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_3873 | - | 8e-73 | 42.94% (347) | dehydratase |
| M. vanbaalenii PYR-1 | Mvan_4155 | - | 6e-91 | 45.45% (418) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2503|M.gilvum_PYR-GCK -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
Mvan_4155|M.vanbaalenii_PYR-1 -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
MSMEG_4798|M.smegmatis_MC2_155 -----MSGPLEGIRILEVAMYGFVPSAGAVLGEWGADVIKVEHAVTGDPQ
MMAR_4713|M.marinum_M ------MKPLEGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
TH_4667|M.thermoresistible__bu --------------VLEVAQWTFVPAAGAVLADWGADVIKVEHPRTGDSQ
MAV_1895|M.avium_104 -----MQKPMTGVRVLEVAQFTFVPSAGAVLADWGADVIKVENPVTGDAQ
MUL_3873|M.ulcerans_Agy99 ----------------------------MAFSTWGG--------IALDPE
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
MAB_4651c|M.abscessus_ATCC_199 -----MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPDPL
: *. .
Mflv_2503|M.gilvum_PYR-GCK RGLRQTGLLRVEG---DPNPNIEHANRLKRSIGLDMSVPEGKEVLLELAR
Mvan_4155|M.vanbaalenii_PYR-1 RGLRQTGLLRVEG---DPNPNIEHANRLKRSIGLDMSVAEGREVLLELAR
MSMEG_4798|M.smegmatis_MC2_155 RGLRQTGPLRVDG---DPNPNIEHANRGKRSIGLDMSVPAGREVLLELAR
MMAR_4713|M.marinum_M RGLRQTGMLRVEG---DPNPNIEHANRGKRSLGLDMSISEGKEVLHELAR
TH_4667|M.thermoresistible__bu RGLRSLGHITIEG---DRNPVMEHANRGKRSVAIDMSTPDGHELLMEIAR
MAV_1895|M.avium_104 RGLVTVAGRSATAPGVSFSPMVEAPNRGKRSVGLSLALKQTRPVFEELVR
MUL_3873|M.ulcerans_Agy99 R-----------------HPLIEHPNRGKRSVGIDLATSDGQDVLHELAR
Mb3300|M.bovis_AF2122/97 QITSVLPGRPPLA------TYFLPNNRGKKSVTVDLTTEQAKQQMLRLAD
Rv3272|M.tuberculosis_H37Rv QITSVLPGRPPLA------TYFLPNNRGKKSVTVDLTTEQAKQQMLRLAD
MAB_4651c|M.abscessus_ATCC_199 R---TWGQAEVDG----HHVFWTVHARNKKAITLDLRTEAGRALFLDLVD
: * *::: :.: : : :.
Mflv_2503|M.gilvum_PYR-GCK RADVFLTSFLPGHRQKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGG
Mvan_4155|M.vanbaalenii_PYR-1 RADVFLTSFLPGHRQKFGIDVDDIRAANPKIVYARGSALGPRGEESVKGG
MSMEG_4798|M.smegmatis_MC2_155 RADVFLTSFLPGHREKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGG
MMAR_4713|M.marinum_M RSDVFLTSFLPGARRKFGIDLEDIRAVNPSIIYARGSALGPRGEEAAKGG
TH_4667|M.thermoresistible__bu TSDVFLTNFLPEARKKLRIDVEDLRAVNPDIVYARGSAYGPLGAEAEIGG
MAV_1895|M.avium_104 RSDVFLTNLLPQARAKLRIHLEEIRRINPSIIYVTGSGFGSQGPDRETGA
MUL_3873|M.ulcerans_Agy99 SADVFLTNYLPSARQKNKFDVEHVRGANPDIIYARGTAYGDKGAERDVGG
Mb3300|M.bovis_AF2122/97 TADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPG
Rv3272|M.tuberculosis_H37Rv TADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPG
MAB_4651c|M.abscessus_ATCC_199 KSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAG
:**.: * : : : : * :: . :. * * . .
Mflv_2503|M.gilvum_PYR-GCK YDMTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALL
Mvan_4155|M.vanbaalenii_PYR-1 YDMTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALL
MSMEG_4798|M.smegmatis_MC2_155 YDMTAFWCRAGAAATITPPGIEGMIGPPGPAYGDTISGTNLAGGIAAALF
MMAR_4713|M.marinum_M YDMTAFWCRAGTAATITPMGYQGMINPPGPAYGDTISGTNLAGGIAAALL
TH_4667|M.thermoresistible__bu YDMTGFWSRAAGAMGSTPSDMEGVVPQPGPAYGDSIGGMTIAGGIAAALF
MAV_1895|M.avium_104 HDTTAFWARAGNADGVTPSDSEVPTGIPAGAFGDNVGGITIAGAVAAALY
MUL_3873|M.ulcerans_Agy99 YDGTAFWTRSGVGHALTPPELGAPLAQGIPAFGDSIGGMNIAGGISAALL
Mb3300|M.bovis_AF2122/97 IDLVVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVLAALL
Rv3272|M.tuberculosis_H37Rv IDLVVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVLAALL
MAB_4651c|M.abscessus_ATCC_199 YASVAEAASGLRHLNGFPGGPP---PRMALSIGDTLAGMFAAQGALAALY
. . * *. .* * . ***
Mflv_2503|M.gilvum_PYR-GCK KRERSGEPSVVDVSLLGSGLWALGHTVALTTHLGQRMEAFPPGVHGSPIN
Mvan_4155|M.vanbaalenii_PYR-1 KRERTGEPSIVDVSLLGSGLWALGHTVALTNHLHERMEAFPPGAHGSPIN
MSMEG_4798|M.smegmatis_MC2_155 KRERTGEPSVVDVSLLGSGLWAMGHTIALTSHLNELMVQPPPGVHGSPIN
MMAR_4713|M.marinum_M KRERTGEPSVVDVSLLGSGLWSLGHTVALTRHLGQRLEAPPPGIHGSPIN
TH_4667|M.thermoresistible__bu ERERTGVARVVDISLLGVGVWASGVAINAALISGQPWIPNPTGANVAPNN
MAV_1895|M.avium_104 GRQTTGQTSVIDVSLLAVGAWANQSNVNLAMLYGCPLPKIDHRTQ-APGN
MUL_3873|M.ulcerans_Agy99 HRERTGEALEVDVSLLSTAWWAAGASMTQGMDTGETMRSRMPQSGGMPMN
Mb3300|M.bovis_AF2122/97 HRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRR
Rv3272|M.tuberculosis_H37Rv HRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRR
MAB_4651c|M.abscessus_ATCC_199 RRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEGIAPS
* .* :: :: :
Mflv_2503|M.gilvum_PYR-GCK PLVG-------LYATADDRYISFVMMQPTKFWADVCKHMDLDELADDPRF
Mvan_4155|M.vanbaalenii_PYR-1 PLVG-------LYPTADDRYISFVMMQPTKFWADVCSHMDLDELVDDPRF
MSMEG_4798|M.smegmatis_MC2_155 PLVG-------LYGTADGRYISFVMMQPTKFWADVCRHMDLEHYIDDPRF
MMAR_4713|M.marinum_M PLVG-------VYATSDGRYISLVMMQPTKFWADVCRHIDRPDLAEDPRF
TH_4667|M.thermoresistible__bu PLVG-------FYRTADGRFLSLSMLQGFRFFGEFCKRIGVGELAADERF
MAV_1895|M.avium_104 PLTG-------AYRCSDGRFIQLAMLQPTRYWAPVCRLFGLDAAAADERF
MUL_3873|M.ulcerans_Agy99 PFMG-------NYQTSDGGTINLCILSPTGYIRDTFEHLGIPEAADDPRF
Mb3300|M.bovis_AF2122/97 KGVGFATQPSDAFRTADG-YIVISAYVP-KHWQKLCYLIGRPDLVEDQRF
Rv3272|M.tuberculosis_H37Rv KGVGFATQPSDAFRTADG-YIVISAYVP-KHWQKLCYLIGRPDLVEDQRF
MAB_4651c|M.abscessus_ATCC_199 ----------NIYQSADGSWVVIAANQDTVFRR-LCEAMGRPELSSDARF
: :*. : : . :. * **
Mflv_2503|M.gilvum_PYR-GCK ATAESIAEHTALANEILTEAMAKRPLTEWSERFATLAGPWAPVQDTLQAA
Mvan_4155|M.vanbaalenii_PYR-1 ATAESIAENTADAAEILKEAMSKRTLAEWSERFATLAGPWAPVQDTLQAA
MSMEG_4798|M.smegmatis_MC2_155 ATAESIAENTAAAVDILTEAMKKRTLPEWSERFATLAGPWAPVQDTLQAA
MMAR_4713|M.marinum_M ATVEKIAAHTADAVEILTKAISARTLAEWSERFATLAGPWAPVQDTLQAA
TH_4667|M.thermoresistible__bu ASHAALTANAAAATEILRATIAAQPLEHWRRVLDGFEGQWAVVQNTAEVA
MAV_1895|M.avium_104 ASLESLAAHTDEATALLAEAIGARTFDECMQLLKLLHGQWAPVQDAWEVA
MUL_3873|M.ulcerans_Agy99 GEAEQLLRNADAAGALIARAVAARPFEYWRQRLKTMKGQWAPFQSLIELA
Mb3300|M.bovis_AF2122/97 AEQRSRSINYAELTAELELALASKTATEWVQLLQAN-GLMACLAHTWKQV
Rv3272|M.tuberculosis_H37Rv AEQRSRSINYAELTAELELALASKTATEWVQLLQAN-GLMACLAHTWKQV
MAB_4651c|M.abscessus_ATCC_199 ANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADVV
. : : : : . . . .
Mflv_2503|M.gilvum_PYR-GCK EDAQIRAN----EYLVQ-AGE--LELVSNPVQFDVAAPVSGPAPGFA--E
Mvan_4155|M.vanbaalenii_PYR-1 EDAQVRAN----EYLVQ-AGE--LELVANPVQFDVAAPASGPAPGFA--E
MSMEG_4798|M.smegmatis_MC2_155 QDAQIRAN----EYLVQ-AGE--LELVTNPVQFDVSAPSPGPAPGFA--E
MMAR_4713|M.marinum_M DDAQVRAN----EYVVR-AGE--LELVANPVQFDVAAPQTGPAPGFA--E
TH_4667|M.thermoresistible__bu ADPQVRANGGIVEVETG-SGK--TELVASPVLFDETPLNLRPMPEFA--A
MAV_1895|M.avium_104 NDESLVANGRIANVLDA-QGNP-QRLVANPVKFDEAATHLTRAPMFA--E
MUL_3873|M.ulcerans_Agy99 DDEQALANDMVAEVDLG-AGGPPFRVVRGPVQFNHEPLTTTRAPQPG--E
Mb3300|M.bovis_AF2122/97 VDTPLFAES-DLTLEVG-RGADTITVIRTPARYASFRAVVTDPPPTA--G
Rv3272|M.tuberculosis_H37Rv VDTPLFAEN-DLTLEVG-RGADTITVIRTPARYASFRAVVTDPPPTA--G
MAB_4651c|M.abscessus_ATCC_199 QDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQD
* *. * *. *
Mflv_2503|M.gilvum_PYR-GCK QTDDILVELGLDWDRIIELKTAGAVT
Mvan_4155|M.vanbaalenii_PYR-1 QTDDILVELGLDWDRIIELKTAGAVT
MSMEG_4798|M.smegmatis_MC2_155 QTDDILAELGLDWDRIIELKTAGAVT
MMAR_4713|M.marinum_M QTDDILLELGFDWDRIIELKTAGAVT
TH_4667|M.thermoresistible__bu DTEQLILELGGDWDRITALKDSGAIA
MAV_1895|M.avium_104 HTDEVLRELGMADHELIELKIEGAIT
MUL_3873|M.ulcerans_Agy99 HTETVLLELGMDWDRIDQLKRSGAIS
Mb3300|M.bovis_AF2122/97 EHNAVFLARP----------------
Rv3272|M.tuberculosis_H37Rv EHNAVFLARP----------------
MAB_4651c|M.abscessus_ATCC_199 NDDVYVGLLGKSAQDIERLRAEGVL-
. : .